|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Long noncoding RNA(lncRNA)HOTAIR:Pathogenic roles and therapeutic opportunities in gastric cancer显示文摘Gastric cancer is one of the first malignant cancers in the world and a large number of people die every year due to this disease.Many genetic and epigenetic risk factors have been identified that play a major role in gastric cancer.HOTAIR is an effective epigenetic agent known as long noncoding RNA(lncRNA).HOTAIR has been described to have biological functions in biochemical and cellular processes through interactions with many factors,leading to genomic stability,proliferation,survival,invasion,migration,metastasis,and drug resistance.In the present article,we reviewed the prognostic value of the molecular mechanisms underlying the HOTAIR regulation and its function in the development of Gastric Cancer,whereas elucidation of HOTAIR–protein and HOTAIR–DNA interactions can be helpful in the identification of cancer processes,leading to the development of potential therapeutic strategies. | Wencheng Kong Guang Yin Sixin Zheng Xinchun Liu Akao Zhu Panpan Yu Jian Zhang Yuqiang Shan Rongchao Ying Huicheng Jin | 2022 | Genes & Diseases2022，9，5： | 3 |
| 2 | Adjustable thermal expansion in La(Fe,Si)13-based conductive composites by high-pressure synthesis显示文摘Providing a suitable contact interface, where a high conductivity material with a desirable coefficient of thermal expansion(CTE) adjoins the target micro-electric devices, is very crucial to optimize the properties and service life of the relevant instruments. Regrettably, a high conductivity, low thermal expansion and relatively inexpensive material is very rare. Composites, fortunately, can offer a method to design materials with adjustable properties by mixing two or more diverse constituents. In this paper, high conductivity composites with adjustable thermal expansion were successfully prepared by a high-pressure synthesis. The composites are based on combining La(Fe,Si)13-based compounds, the materials showing a giant, isotropic negative thermal expansion(NTE) properties, within Cu matrix. The La(Fe,Si)13-based compounds were used to adjust the CTE of the composites, while the Cu phase is in charge of tuning the thermal conductivity properties. Thus, by changing the relative amount of the two components, the composites with high conductivities and adjustable CTE were achieved. Furthermore, the thermal expansion and magnetic properties of the composites were investigated by a physical property measurement system. The present results highlight the potential applications of the Cu-based high conductivity composites with room-temperature NTE properties in the thermal contacts to various semiconductor and microelectronic devices. | Wei Wang Rongjin Huang Yi Shan Yuqiang Zhao Xinran Shan Shibin Guo Chuanjun Huang Laifeng Li | 2019 | Progress in Natural Science:Materials International2019，29，1： | 2 |
| 3 | An Improved Path Delay Variability Model via Multi-Level Fan-Out-of-4 Metric for Wide-Voltage-Range Digital CMOS Circuits显示文摘In advanced CMOS technology,process,voltage,and temperature(PVT)variations increase the paths’latency in digital circuits,especially when operating at a low supply voltage.The fan-out-of-4 inverter chain(FO4 chain)metric has been proven to be a good metric to estimate the path’s delay variability,whereas the previous work ignored the non-independent characteristic between the adjacent cells in a path.In this study,an improved model of path delay variability is established to describe the relationship between the paths’max-delay variability and an FO4 chain,which is based on multilevel FO4 metric and circuit-level parameters knobs(i.e.,cell topology and driving strength)of the first few cells.We take the slew and load into account to improve the accuracy of this framework.Examples of 28 nm and 40 nm digital circuits show that our model conforms with Monte Carlo simulations as well as fabricated chips’measurements.It is able to model the delay variability effectively to speed up the design process with limited accuracy loss.It also provides a deeper understanding and quick estimation of the path delay variability from the near-threshold to nominal voltages. | CUI Yuqiang SHAN Weiwei DAI Wentao LIU Xinning GUO Jingjing CAO Peng | 2023 | Chinese Journal of Electronics2023，32，2： | 0 |
| 4 | An efficient path delay variability model for wide-voltage-range digital circuits显示文摘Dear editor,As process technology advances, the parasitic effects of integrated circuits become increasingly prominent, posing serious challenges for integrated circuit design [1, 2]. Variations in the process corner, voltage, and temperature(PVT) have a more significant impact on path delay in digital circuits in advanced processes, especially at the near-threshold voltage(NTV) [3, 4]. The delay variability of the critical path needs to be evaluated to minimize the timing margin while ensuring reliability. | Weiwei SHAN Yuqiang CUI Wentao DAI Xinning LIU Jingjing GUO Peng CAO Jun YANG | 2023 | Science China(Information Sciences)2023，66，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员