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| 1 | Human enamel thickness and ENAM polymorphism显示文摘The tooth enamel development gene, enamelin(ENAM), showed evidence of positive selection during a genome-wide scan of human and primate DNA for signs of adaptive evolution. The current study examined the hypothesis that a single-nucleotide polymorphism(SNP) C14625T(rs7671281) in the ENAM gene identified in the genome-wide scan is associated with a change in enamel phenotype. African Americans were selected as the target population, as they have been reported to have a target SNP frequency of approximately 50%, whereas non-Africans are predicted to have a 96% SNP frequency. Digital radiographs and DNA samples from 244 teeth in 133 subjects were analysed, and enamel thickness was assessed in relation to SNP status,controlling for age, sex, tooth number and crown length. Crown length was found to increase with molar number, and females were found to have thicker enamel. Teeth with larger crowns also had thicker enamel, and older subjects had thinner enamel.Linear regression and generalized estimating equations were used to investigate the relationship between enamel thickness of the mandibular molars and ENAM SNP status; enamel in subjects with the derived allele was significantly thinner(P = 0.040)when the results were controlled for sex, age, tooth number and crown length. The derived allele demonstrated a recessive effect on the phenotype. The data indicate that thinner dental enamel is associated with the derived ENAM genotype. This is the first direct evidence of a dental gene implicated in human adaptive evolution as having a phenotypic effect on an oral structure. | Diane M Daubert Joanna L Kelley Yuriy G Udod Carolina Habor Chris G Kleist Ilona K Furman Igor N Tikonov Willie J Swanson Frank A Roberts | 2016 | International Journal of Oral Science2016，8，2： | 2 |
| 2 | Production of dimethylfuran for liquid fuels from biomass-derived carbohydrates显示文摘 | Yuriy R L Christopher J B Zhen Y L | 2007 | Nature2007，447，： | 1 |
| 3 | Production of dimethylfuran for liquid fuels from biomass-derived carbohydrates 显示文摘 | Yuriy R L Christopher J B Zhen Y L | 2007 | Nature2007，447，： | 1 |
| 4 | Production of dimethylfuran for liquid fuels from biomass-derived carbohydrates 显示文摘 | YURIY R L CHRISTOPHER J B ZHEN Y | 2007 | Nature2007，447，7147： | 1 |
| 5 | Perfluoroalkylation of heterocumulenes with trimethyl(perfluoroalkyl)silanes in the presence of fluoride ions:synthesis of perfluoroalkanesulfiny amides from N-organylsulfinyl amines显示文摘 | Yurii L Yagupolskii Nataliya V Kirij Aleksey V Shevchenko | 2002 | Tetrahedron Lett2002，43，： | 1 |
| 6 | XPS and TEM studies on the role of the support and alkali promoter in Ru/MgO and Ru-Cs+/MgO catalysts for ammonia synthesis显示文摘 | Larichev Yurii V Moroz Boris L Zaikovskii Vladimir I | 2007 | J Phys Chem C2007，111，： | 1 |
| 7 | Structure and biological activity of the short-chain lipopolysaccharide from Bartonella henselae ATCC 49882T显示文摘 | Ulrich Z Buko L Yuriy AK | 2004 | Journal of Biological Chemistry2004，279，21： | 1 |
| 8 | Phase modifiers promote efficient production of hydroxymethylfurfural from fructose显示文摘 | YURIY R L JUBEN N C JAMES A D | 2006 | Science2006，312，5782： | 1 |
| 9 | Association betweenreport of insomnia and daytime functioning显示文摘 | Yuriy Ustinov Kenneth L Lichstein | 2010 | Sleep Medicine2010，11，： | 1 |
| 10 | Production of dimethylfuran for liquid fuels from biomass-derived carbohydrates 显示文摘 | YURIY R L CHRISTOPHER J B ZHEN Y L | 2007 | Nature2007，447，： | 1 |
| 11 | Use of halophytic plants for recycling NaC1 in human liquid waste in a bioregen- erative life support system显示文摘 | Yurii B Myasoedov N Popova L | 2010 | Advances in Space Research2010，46，2010： | 1 |
| 12 | Liver resection for early hepatocellular cancer: Comparison of centers in 3 different countries显示文摘AIM To compare patients who underwent resection of early stage hepatocellular cancer(HCC) in three different countries. METHODS This retrospective study characterizes 573 stage Ⅰ/Ⅱ HCC patients treated with liver resection in 3 tertiaryreferral centers: Tokyo(n = 250), Honolulu(n = 146) and Shanghai(n = 177).RESULTS Shanghai patients were younger, predominantly male, hepatitis-B seropositive(94%) and cirrhotic(93%). Tokyo patients were older and more likely to have hepatitis-C(67%), smaller tumors, low albumin, and normal alpha-fetoprotein. The Honolulu cohort had the largest tumors and 30% had no viral hepatitis. Ageadjusted mortality at 1 and 5-years were lower in theTokyo cohort compared to Honolulu and there was no difference in mortality between Shanghai and Honolulu cohorts. Elevated alpha-fetoprotein, low albumin and tumor > 5 cm were associated with increased 1-year mortality. These factors and cirrhosis were independently associated with increased 5-year mortality. Independent risk factors of survival varied when examined separately by center. CONCLUSION The profile of early-stage HCC patients is strikingly different across countries and likely contributes to survival differences. Underlying differences in patient populations including risk factors/comorbidities influencing disease progression may also account for variation in outcomes. | Linda L Wong Brenda Y Hernandez Yurii B Shvetsov Yoichi Kawano Zhao-You Tang Jun-Fang Ji | 2016 | World Journal of Hepatology2016，8，31： | 1 |
| 13 | Production of dimethylfuran for liquid fuels from biomass-derived carbo- hydrates显示文摘 | Yuriy R L Barrett C J Dumesic J A | 2007 | Nature2007，447，7147： | 1 |
| 14 | Preparation and Characterization of Energetic A1-Mg Mechanical Alloy Powders 显示文摘 | Yuriy L Shoshin Ruslan S Mudryy Edward L Dreizin | 2002 | Combustion and Flame2002，128，3： | 1 |
| 15 | Constant Pressure Flames of Aluminum and Aluminum- Magnesium Mechanical Alloy Aerosols in Microgravity 显示文摘 | Edward L Dreizin Yuriy L Shoshin Ruslan S Mudeyy | 2002 | Combustion and Flame2002，130，4： | 1 |
| 16 | XPS and TEM studies on the role of the support and alkali promoter in Ru/MgO and Ru-Cs +/MgO catalysts for ammonia synthesis显示文摘 | Larichev Yurii V Moroz Boris L Zaikovskii Vladimir I | | 0，，： | 1 |
| 17 | Preparation and characterization of engertic Al-Mg mechanical alloy powders显示文摘 | Shoshin Yuriy L Mudryy Ruslan S Dreizin Edward L | 2002 | Combustion and Flame2002，128，3： | 1 |
| 18 | Expression profiling identifies microRNA signature in pancreatic cancer显示文摘 | Eun J L Yuriy G Jinmai J | 2007 | Int J Cancer2007，120，5： | 1 |
| 19 | Preparation and characterization of energetic AI-Mg mechanical alloy powders 显示文摘 | Yuriy L Shoshin Ruslan S | 2002 | Combustion and Flame2002，128，： | 1 |
| 20 | Active control of slow light on a chip with photonic crystal waveguides显示文摘 | YURII A VLASOV L MARTIN O | 2005 | Nature2005，438，3： | 1 |
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