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| 1 | MnO_(2) cathode materials with the improved stability via nitrogen doping for aqueous zinc-ion batteries显示文摘The research and exploration of manganese-based aqueous zinc-ion batteries have been controversial of cycle stability and mechanism investigation,thus improving the stability and exploring storage mechanism are still the most main issue.Defect engineering has become an effective method to improve cycle stability.Herein,a nitrogen-doped ε-MnO_(2)(MnO_(2)@N)has been prepared using electrochemical deposition and heat treatment under nitrogen atmosphere.As the cathode for zinc-ion batteries,the capacity retention rate of MnO_(2)@N cathode is close to 100%after 500 cycles at 0.5 A g^(-1),while the capacity retention rate for the initial MnO_(2) cathode is 62%.At 5 A g^(-1),the capacity retention rate of MnO_(2)@N cathode is 83%after 1000 cycles,which is much higher than the 27%capacity retention rate for the original MnO_(2) cathode.And it can be found that the oxygen vacancies increase after nitrogen doping,which can improve the conductivity of the MnO_(2)@N cathode.Also,there is Mn-N bond in MnO_(2)@N,which can enhance the electrochemical stability of MnO_(2)@N cathode.In addition,the electrochemical mechanism of MnO_(2)@N cathode has been explored by the CV,GCD and GITT tests.It is found that nitrogen doping promotes the intercalation of H^(+) and the corresponding capacity contribution.Compared with the original MnO_(2) cathode,the diffusion coefficient of H^(+) and Zn^(2+) in MnO_(2)@N cathode increases.Also,the reactions during the charging and discharging process are explored through the ex-situ XRD test.And this work may provide some new ideas for improving the stability of manganese-based zinc-ion batteries. | Yanan Zhang Yanpeng Liu Zhenhua Liu Xiaogang Wu Yuxiang Wen Hangda Chen Xia Ni Guohan Liu Juanjuan Huang Shanglong Peng | 2022 | Journal of Energy Chemistry2022，31，1： | 6 |
| 2 | Genome-wide Investigation of micro RNAs and Their Targets in Brassica rapa ssp. pekinensis Root with Plasmodiophora brassicae Infection显示文摘Increasing evidence has revealed that micro RNAs play a pivotal role in the post transcriptional regulation of gene expression in response to pathogens in plants. However, there is little information available about the expression patterns of mi RNAs and their targets in Chinese cabbage(Brassica rapa ssp. pekinensis) under Plasmodiophora brassicae stress. In the present study, using deep sequencing and degradome analysis, a genome-wide identification of mi RNAs and their targets during P. brassicae stress was performed. A total of 221 known and 93 potentially novel mi RNAs were successfully identified from two root libraries of one control(635-10CK) and P. brassicae-treated Chinese cabbage samples(635-10T). Of these, 14 known and 10 potentially novel mi RNAs were found to be differentially expressed after P. brassicae treatment. Degradome analysis revealed that the 223 target genes of the 75 mi RNAs could be potentially cleaved. KEGG(Kyoto Encyclopedia of Genes and Genomes)pathway analysis suggested that the putative target genes of the mi RNAs were predominately involved in selenocompound metabolism and plant hormone signal transduction. Then the expression of 12 mi RNAs was validated by quantitative real-time PCR(q RT-PCR). These results provide insights into the mi RNA-mediated regulatory networks underlying the stress response to the plant pathogen P. brassicae. | WEI Xiaochun XU Wen YUAN Yuxiang YAO Qiuju ZHAO Yanyan WANG Zhiyong JIANG Wusheng ZHANG Xiaowei | 2016 | Horticultural Plant Journal2016，2，4： | 3 |
| 3 | Characteristics of cow’s milk allergy and sensitization in Chinese patients显示文摘Globally,the prevalence of food allergy in children is estimated to be approximately 4%to 10%.[1]Food allergy usually begins early in the allergic march,and cow's milk allergy(CMA)is one of the most common food allergens in infants and children.In Europe,the overall incidence of challenge-proven CMA is 0.54%,and in the United States,the overall prevalence is 0.4%and pediatric prevalence is 1.9%.[2–4]In China,the prevalence of oral food challenge(OFC)-confirmed CMA is 0.83%to 3.5%in various cities.[5]Double-blind placebo-controlled food challenge is not applied widely in clinical practice because of its complex process and the risk of anaphylaxis for patients that receive the test.Allergen-specific IgE(sIgE)is usually used as a critical assessment method for food allergy. | Sainan Bian Ruiqi Wang Tao Xu Kai Guan Liping Wen Lianglu Wang- Jjanqing Gu Jinlyu Sun Rui Tang Yuxiang Zhi Hong Li Jia Yin | 2022 | Chinese Medical Journal2022，135，22： | 1 |
| 4 | Identification of Stable Quantitative Trait Loci for Sheath Blight Resistance Using Recombinant Inbred Line显示文摘To identify stable quantitative trait loci(QTLs)responsible for sheath blight resistance,a recombinant inbred line mapping population consisting of 219 lines was developed by crossing Lemont and Yangdao 4.Average disease rating,average lesion length,maximum disease rating and maximum lesion length were assayed in six different environments.A total of 128 minor effect QTLs were detected by multiple interval mapping.These QTLs explained less than 11.2%of the phenotypic variations individually,and 106 QTLs were clustered in 20 QTL-rich regions/putative loci.Significant QTL×environment interactions were detected at three putative loci(qSBR11.1,qSBR11.2 and qSBR11.3),indicating that these three loci were not stable.The other 17 stable loci(qSBR1.1,qSBR1.2,qSBR2.1,qSBR2.3,qSBR3.1,qSBR3.2,qSBR3.5,qSBR3.6,qSBR5.1,qSBR7.1,qSBR8.1,qSBR9.1,qSBR9.2,qSBR9.3,qSBR12.1,qSBR12.2 and qSBR12.4)provided a foundation for marker-assisted selection in breeding.Analysis of allelic effect on the 20 putative loci identified 7 highly stable loci,including qSBR3.2,qSBR7.1,qSBR8.1,qSBR9.2,qSBR9.3,qSBR12.1 and qSBR12.2. | CHEN Yuan ZENG Yuxiang JI Zhijuan LIANG Yan WEN Zhihua YANG Changdeng | 2019 | Rice science2019，26，5： | 1 |
| 5 | Designable heteronanocrystals via interface redox reaction显示文摘The synergistic interaction of different components in heteronanocrystals induces interfacial phenomena and novel functionalities.Nonetheless,effective technologies to design and fabricate heteronanocrystals with materials on demand are still missing.Rich heterostructures in a copper patina are known to form at room temperature and under atmospheric pressure.The redox process of copper tarnish inspired the discovery of a simple strategy to achieve heteronanocrystals that contained elements from group 3-11 and group 14-16.The interface redox-induced method is self-regulating at ambient conditions and applicable for metal,semiconductor,and dielectric materials.The enhanced interface bonding endows the heteronanocrystals with outstanding stability and catalytic performance,while the modular approach enables the design and fabrication of heteronanocrystals with intended materials to meet different purposes. | Zhihua Li Yang Li Nannan Luo Yuanyuan Qie Dingyi Yang Guowei Cao Yuxiang Liu Ying Fu Na Li Wen Hu Min Zhang Rusen Yang Bo Tang | 2023 | Nano Research2023，16，4： | 0 |
| 6 | Statistical delay distribution analysis on high-speed railway trains显示文摘The focus of this study is to explore the statis-tical distribution models of high-speed railway (HSR) train delays. Based on actual HSR operational data, the delay causes and their classification, delay frequency, number of affected trains, and space–time delay distributions are discussed. Eleven types of delay events are classified, and a detailed analysis of delay distribution for each classifica-tion is presented. Models of delay probability delay prob-ability distribution for each cause are proposed. Different distribution functions, including the lognormal, exponen-tial, gamma, uniform, logistic, and normal distribution, were selected to estimate and model delay patterns. The most appropriate distribution, which can approximate the delay duration corresponding to each cause, is derived. Subsequently, the Kolmogorov–Smirnov (K–S) test was used to test the goodness of fit of different train delay distribution models and the associated parameter values. The test results show that the distribution of the test data is consistent with that of the selected models. The fitting distribution models show the execution effect of the timetable and help in finding out the potential conflicts in real-time train operations. | Yuxiang Yang Ping Huang Qiyuan Peng Jie LI Chao Wen | 2019 | Journal of Modern Transportation2019，27，3： | 0 |
| 7 | Tilianin extracted from Xiangqinglan(Herba Dracocephali Moldovicae)inhibits apoptosis induced by mitochondrial pathway and endoplasmic reticulum stress in H9c2 cells after oxygen-glucose deprivation/reoxygenation显示文摘OBJECTIVE:To investigate the efficacy of tilianin extracted from Xiangqinglan(Herba Dracocephali Moldovicae)on apoptosis of H9c2 cell after oxygenglucose deprivation/reoxygenation(OGD/R)and the mechanism.METHODS:Tilianin was obtained from Beijing Inluck Science and Technology Development Co.Ltd.,with purity≥98%.The OGD/R model was established in H9c2 cells.Flow cytometry detected the mitochondrial membrane potential,apoptosis rates,mitochondrial reactive oxygen species(ROS)and calcium ion concentration.Succinate dehydrogenase(SDH)activity,succinate content and levels of tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and interleukin-1β(IL-1β)were detected with enzyme-linked immunosorbent assay.Western blot measured protein levels.RESULTS:Tilianin significantly reduced the apoptotic rates,ROS levels,calcium ion concentration,succinate content,and,levels of TNF-α,IL-6 and IL-1βof OGD/R cells,while significantly increased the membrane potential and SDH activity in mitochondria.Western blot analysis showed that tilianin significantly up-regulated pCalmodulin-dependent protein kinaseⅡand voltagedependent anion selective channel levels in OGD/R cells,while significantly down-regulated p-protein kinase B,Bcl-2-associated X,and dynamin-related protein 1 levels related to apoptosis in the mitochondrial pathway.Moreover,tilianin significantly up-regulated B-cell lymphoma-2 and mitochondrial protein 2 related to the inhibition of apoptosis.Furthermore,tilianin downregulated phosphorylated-apoptosis signal-regulated kinase 1,phosphorylated-p38 and C/EBP homologous protein related to endoplasmic reticulum stress.CONCLUSIONS:Tilianin may inhibit OGD/R-induced H9c2 cell apoptosis mediated by mitochondrial pathway and endoplasmic reticulum stress,thus protecting cardiomyocytes. | JIANG Wen ZHANG Wei ZHANG Yuxiang YANG Hao PAN Xiaomei CHEN Qiang CHEN Junhui | 2023 | Journal of Traditional Chinese Medicine2023，43，1： | 0 |
| 8 | Root nutrient capture and leaf resorption efficiency modulated by different influential factors jointly alleviated P limitation in Quercus acutissima across the North–South Transect of Eastern China显示文摘Soil and climatic conditions are known to have close associations with plant morphological and stoichiometric traits at a regional scale along latitudinal gradients;however,how latitude drives biotic and abiotic factors affecting plant nutrient acquisition to accommodate environmental nutrient deficiency remains unclear.We quantified soil,root,leaf,and leaf litter nitrogen(N)and phosphorus(P)concentrations to determine the potentially limiting nutrient and the simultaneous responses of root capture and leaf resorption to nutrient deficiency in seven Quercus acutissima forests across the North–South Transect of Eastern China.The results showed that the mean leaf and root N:P ratios in Q.acutissima were 21.58 and 20.23,respectively,which markedly exceeded the P limitation threshold of 16 for terrestrial plants.The mean leaf litter N and P were 10.63 mg/g and 0.51 mg/g,respectively,indicating that P resorption proficiency was relatively higher than N resorption proficiency.N displayed higher stoichiometric homeostasis than P in the leaf.The leaf and root N:P ratios showed a quadratic variation that first decreased and then increased as latitude increased,whereas the phosphorus resorption efficiency and root-soil accumulation factor of P displayed the opposite trend.Partial least square path modeling(PLS-PM)analysis demonstrated that root nutrient capture and leaf nutrient resorption were regulated by different influential factors.Overall,these findings provide new insights into plant strategies to adapt to environmental nutrient deficiency,as well as the scientific basis for predicting the spatial and temporal patterns of nutrient acquisition in the context of climate change. | Ran Tong Yuxiang Wen Jingyuan Wang Chenyang Lou Cong Ma Nianfu Zhu Wenwen Yuan GGeoff Wang Tonggui Wu | 2022 | Forestry Research2022，2，1： | 0 |
| 9 | Diagnostic accuracy and safety of Dermatophagoides pteronyssinus extracts used for skin prick test显示文摘Background:Dermatophagoides pteronyssinus is a common allergen causing allergic diseases in China.The aim of this study was to evaluate the efficacy and safety of D.pteronyssinus extracts produced by Peking Union Medical College Hospital(PUMCH)for the skin prick test(SPT)in the diagnosis of D.pteronyssinus allergy.Methods:A total of 910 subjects with allergic diseases were prescribed D.pteronyssinus SPT and specific sIgE(sIgE)test among the Outpatients of Department of Allergy,PUMCH from August 10,2015 to August 30,2017.Receiver operating characteristic curve(ROC)analysis was performed according to the results of D.pteronyssinus-sIgE detection.The accuracy of D.pteronyssinus extracts used for SPT in the diagnosis of D.pteronyssinus allergy was evaluated under different cutoff values.Adverse events after SPT were recorded to evaluate safety.Results:There were 796 and 618 subjects in the full analysis set(FAS)and the per protocol set(PPS),respectively.The areas under the curve of FAS and PPS were 0.871 and 0.873,respectively.According to the ROC of PPS,the optimal and 95%specificity diagnostic cutoff values of D.pteronyssinus SPT mean wheal diameter were 3.25 and 3.75 mm,respectively.No adverse events occurred.Conclusion:The extracts of D.pteronyssinus for SPT were simple,highly accurate,and safe and should be considered for recommendation in the clinical diagnosis of D.pteronyssinus allergy. | Rui Tang Xiaohong Lyu Yuxi Liu Ruiqi Wang Lianglu Wang Hong Li Jinlyu Sun Yuxiang Zhi Jianqing Gu Kai Guan Liping Wen Zixi Wang Lisha Li Le Cui Yingyang Xu Junxiong Zhou Tao Xu Jia Yin | 2022 | Chinese Medical Journal2022，135，21： | 0 |
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