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| 1 | Facile Synthesis of Mo2C Nanocrystals Embedded in Nanopo- rous Carbon Network for Efficient Hydrogen Evolution显示文摘为综合探索灵巧、容易可伸缩的方法地球丰富、划算、有效的氢进化反应(她的) electrocatalysts 作为一个干净、持续的精力搬运人为氢的大量生产是必要的。我们这里报导简单策略生产瞬间 2 在碳网络嵌入的 C nanocrystals (瞬间 2 C@C ) 由铵 molybdate 和 polyvinylpyrrolidone (PVP ) 的直接热分解。PVP 能有效地被用作单身的来源形成碳化物和碳网络,这被发现。有 PVP 的转变金属的长聚合物链和协调能力使形成连接的多孔的碳网络和分散得好的瞬间 2 在几纳米的 C nanocrystals。PVP 的碳化不仅在原处有效地阻止瞬间 2 C nanocrystals 在他们的形成期间,而且提供传导性的多孔的矩阵。作为结果,瞬间 2 C@C 合成展览为她的优异 electrocatalytic 性能,能从很多的小瞬间 2 | Yuyun Chen Yun Zhang Yuling Ma Tang Tang Zhihui Dai Jinsong Hu Lijun Wan | 2017 | Chinese Journal of Chemistry2017，35，6： | 4 |
| 2 | Corrosion engineering boosting bulk Fe_(50)Mn_(30)Co_(10)Cr_(10)high-entropy alloy as high-efficient alkaline oxygen evolution reaction electrocatalyst显示文摘Oxygen evolution reaction(OER)is a critical process in electrocatalytic water splitting.However,the development of low-cost,highly efficient OER electrocatalysts by a simple method that can be used for industrial application on a large scale is still a huge challenge.Recently,high entropy alloy(HEA)has acquired extensive attention,which may provide answers to the current dilemma.Here,we report bulk Fe_(50)Mn_(30)Co_(10)Cr_(10),which is prepared by 3D printing on a large scale,as electrocatalyst for OER with high catalytic performance.Especially,an easy approach,corrosion engineering,is adopted for the first time to build an active layer of honeycomb nanostructures on its surface,leading to ultrahigh OER performance with an overpotential of 247 mV to achieve a current density of 10 mA cm^(-2),a low Tafel slope of 63 mV dec^(-1),and excellent stability up to 60 h at 100 mA cm^(-2)in 1 M KOH.The excellent catalytic activity mainly originates from:(1)the binder-free self-supported honeycomb nanostructures and multi-component hydroxides,which improve intrinsic catalytic activity,provide rich active sites,and reduce interfacial resistance;and(2)the diverse valence states for multiple active sites to enhance the OER kinetics.Our findings show that corrosion engineering is a novel strategy to improve the bulk HEA catalytic performance.We expect that this work would open up a new avenue to fabricate large-scale HEA electrocatalysts by 3D printing and corrosion engineering for industrial applications. | Pengfei Zhou Dong Liu Yuyun Chen Mingpeng Chen Yunxiao Liu Shi Chen Chi Tat Kwok Yuxin Tang Shuangpeng Wang Hui Pan | 2022 | Journal of Materials Science & Technology2022，，14： | 3 |
| 3 | Nanopolyphenol rejuvenates microglial surveillance of multiple misfolded proteins through metabolic reprogramming显示文摘Microglial surveillance plays an essential role in clearing misfolded proteins such as amyloid-beta,tau,andα-synuclein aggregates in neurodegenerative diseases.However,due to the complex structure and ambiguous pathogenic species of the misfolded proteins,a universal approach to remove the misfolded proteins remains unavailable.Here,we found that a polyphenol,α-mangostin,reprogrammed metabolism in the disease-associated microglia through shifting glycolysis to oxidative phosphorylation,which holistically rejuvenated microglial surveillance capacity to enhance microglial phagocytosis and autophagy-mediated degradation of multiple misfolded proteins.Nanoformulation ofα-mangostin efficiently deliveredα-mangostin to microglia,relieved the reactive status and rejuvenated the misfolded-proteins clearance capacity of microglia,which thus impressively relieved the neuropathological changes in both Alzheimer’s disease and Parkinson’s disease model mice.These findings provide direct evidences for the concept of rejuvenating microglial surveillance of multiple misfolded proteins through metabolic reprogramming,and demonstrate nanoformulatedα-mangostin as a potential and universal therapy against neurodegenerative diseases. | Dayuan Wang Xiao Gu Xinyi Ma Jun Chen Qizhi Zhang Zhihua Yu Juan Li Meng Hu Xiaofang Tan Yuyun Tang Jianrong Xu Minjun Xu Qingxiang Song Huahua Song Gan Jiang Zaiming Tang Xiaoling Gao Hongzhuan Chen | 2023 | Acta Pharmaceutica Sinica B2023，13，2： | 1 |
| 4 | Generalized Split-Window Algorithm for Estimate of Land Surface Temperature from Chinese Geostationary FengYun Meteorological Sat-ellite (FY-2C) Data显示文摘 | Bohui Tang Yuyun Bi | 2008 | Sensors2008，，8： | 1 |
| 5 | Gener-alized split-window algorithm for estimate of land surfacetemperature from Chinese geostationary FengYun meteoro-logical satellite(FY-2C)data显示文摘 | TANG BOHUI BI YUYUN LI ZHAOLIANG el al | 2008 | Sensors2008，8，： | 1 |
| 6 | Optimization of synergistic energy storage density and efficiency for eco-friendly (Na_(0.5)Bi_(0.5))_(0.6)Sr_(0.4)TiO_(3)-based relaxor ferroelectric ceramics显示文摘Inspired by increasing demand of advanced pulsed power capacitors,the development of lead-free dielectric ceramic capacitors with high energy storage density and temperature-insensitive performance are extremely crucial.Herein,the lead-free relaxor ferroelectric ceramics based on(1-x)(Na_(0.5)Bi_(0.5))0.6Sr_(0.4)TiO_(3-x)Sr_(0.7)La_(0.2)ZrO_(3)[abbreviated as(1-x)NBST-xSLZ]are prepared by the solid-state reaction route.The large recoverable energy density(Wrec)of 3.45 J/cm^(3) and efficiency(h)of 90.1%are simultaneously realized in 0.86NBST-0.14SLZ ceramic due to increased breakdown strength.Furthermore,both the Wrec and h of 0.86NBST-0.14SLZ ceramic display superior of thermal stability(20e180C),frequency stability(1e1000 Hz),and cycle stability(10^(4))within a satisfactory range of variation.In addition,the 0.86NBST-0.14SLZ ceramic can also achieve a large current density(CD)of 625 A/cm^(2),an ultrahigh power density(PD)of 50 MW/cm^(3) and a fast discharge rate(t0.90)of 160.8 ns at 160 kV/cm.These results demonstrate that the 0.86NBST-0.14SLZ ceramic could be a highly competitive and ecofriendly relaxor ferroelectric material for next-generation pulsed power capacitors. | Hu Di Pan Zhongbin Wu Lukang Yang Fan Tang Luomeng Zhao Jinghao Shen Yihao Chen Yuyun Li Peng Zhai Jiwei Liu Jinjun | 2021 | Journal of Materiomics2021，7，4： | 0 |
| 7 | The effect of drug loading and multiple administration on the protein corona formation and brain delivery property of PEG-PLA nanoparticles显示文摘The presence of protein corona on the surface of nanoparticles modulates their physiological interactions such as cellular association and targeting property.It has been shown that α-mangostin(αM)-loaded poly(ethylene glycol)-poly(l-lactide)(PEG-PLA)nanoparticles(NP-αM)specifically increased low density lipoprotein receptor(LDLR)expression in microglia and improved clearance of amyloid beta(Aβ)after multiple administration.However,how do the nanoparticles cross the blood‒brain barrier and access microglia remain unknown.Here,we studied the brain delivery property of PEG-PLA nanoparticles under different conditions,finding that the nanoparticles exhibited higher brain transport efficiency and microglia uptake efficiency afterαM loading and multiple administration.To reveal the mechanism,we performed proteomic analysis to characterize the composition of protein corona formed under various conditions,finding that both drug loading and multiple dosing affect the composition of protein corona and subsequently influence the cellular uptake of nanoparticles in b.End3 and BV-2 cells.Complement proteins,immunoglobulins,RAB5A and CD36 were found to be enriched in the corona and associated with the process of nanoparticles uptake.Collectively,we bring a mechanistic understanding about the modulator role of protein corona on targeted drug delivery,and provide theoretical basis for engineering brain or microglia-specific targeted delivery system. | Yuyun Tang Jinchao Gao Tao Wang Qian Zhang Antian Wang Meng Huang Renhe Yu Hongzhuan Chen Xiaoling Gao | 2022 | Acta Pharmaceutica Sinica B2022，12，4： | 0 |
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