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| 1 | Dynamic modeling and optimal control of cystic echinococcosis显示文摘Background:Cystic echinococcosis is one of the most severe helminth zoonosis with a drastic impact on human health and livestock industry.Investigating optimal control strategy and assessing the crucial factors are essential for developing countermeasures to mitigate this disease.Methods:Two compartment models were formulated to study the dynamics of cystic echinococcosis transmission,to evaluate the effectiveness of various control measures,and to find the optimal control strategy.Sensitive analyses were conducted by obtaining PRCCs and contour plot was used to evaluate the effect of key parameters on the basic reproduction number.Based on forward-backward sweep method,numerical simulations were employed to investigate effects of key factors on the transmission of cystic echinococcosis and to obtain the optimal control strategy.Results:The food resources of stray dog and invalid sheep vaccination rate,which are always neglected,were significant to the transmission and control of cystic echinococcosis.Numerical simulations suggest that,the implementation of optimal control strategy can significantly reduce the infections.Improving the cost of health education and domestic dog deworming could not decrease human infections.Conclusions:Our study showed that only a long-term use of the optimal control measures can eliminate the disease.Meanwhile,during the intervention,sheep vaccination and stray dogs disposing should be emphasized ahead of domestic dogs deworming to minimize the control cost.Simultaneously reducing other wild intermediate hosts and strengthening the sheep vaccination as well as disposing the stray dogs would be most effective. | Xinmiao Rong Meng Fan Huaiping Zhu Yaohui Zheng | 2021 | Infectious Diseases of Poverty2021，10，2： | 4 |
| 2 | Different responses to selection in two stocks of the bay scallop, Argopecten irradians irradians Lamarck (1819)显示文摘 | Huaiping Zheng Guofan Zhang Xiao Liu Fusui Zhang Ximing Guo | 2004 | Journal of Experimental Marine Biology and Ecology2004，，2： | 2 |
| 3 | Effects of phenanthrene on hepatic enzymatic activities in tilapia(Oreochromis niloticus ♀×O.aureus ♂)显示文摘The effects of phenanthrene(Phe) on hepatosomatic index(HSI) and hepatic enzymatic activities in hybrid tilapia(Oreochromis niloticus ♀× O.aureus ♂) were investigated via the static freshwater exposure at dosage of 50,100,and 400 μg/L for 4-14 d.Compared with the control group,HSI was significantly decreased(P < 0.05) at 400 μg/L at day 14.Increased enzymatic activities(P < 0.05) were observed for catalase(CAT),glutathione peroxidase(GPx) and superoxide dismutase(SOD) at either 100 or 400 μg/L at day 8 and 14,as well as for CAT at 50 μg/L at day 14,except for GPx at 400 μg/L at day 8.Ethoxyresorufin O-deethylase(EROD) activity was significantly increased(P < 0.05) at all dosage at day 4 as well as at 50 μg/L at day 8,but significantly decreased at either 100 or 400 μg/L at day 14(P < 0.05).Glutathione-S-transferase(GST) activity was not affected.The results suggest that CAT,GPx,SOD and EROD,as well as HSI in tilapia may be used as the biomarkers or indexes for evaluating or monitoring the pollution of polycyclic aromatic hydrocarbons(PAHs) such as Phe. | XU Wenju LI Yuanyou WU Qingyang WANG Shuqi ZHENG Huaiping LIU Wenhua | 2009 | Journal of Environmental Sciences2009，21，6： | 1 |
| 4 | Sustained response to selection in an introduced population of the hermaphroditic bay scallop Argopecten irradians irradians Lamarck (1819)显示文摘 | Huaiping Zheng Guofan Zhang Xiao Liu Ximing Guo | 2005 | Aquaculture2005，，1： | 1 |
| 5 | Sustained response to selection in an introduced population of the hermaphroditic bay scallop Argopecten irradians irradians Lamarck (1819)显示文摘 | Huaiping Zheng Guofan Zhang Xiao Liu Ximing Guo | 2005 | Aquaculture2005，，1： | 1 |
| 6 | Different responses to selection in two stocks of the bay scallop, Argopecten irradians irradians Lamarck (1819)显示文摘 | Huaiping Zheng Guofan Zhang Xiao Liu Fusui Zhang Ximing Guo | 2004 | Journal of Experimental Marine Biology and Ecology2004，，2： | 1 |
| 7 | Total carote- noid differences in scallop tissues of Chlamys nobilis (Bivalve: Pectinidae) with regard to gender and shell colour 显示文摘 | ZHENG Huaiping LIU Helu ZHANG Tao | 2010 | Food Chem2010，122，4： | 1 |
| 8 | Total carotenoid differences in scallop tissues of Chlamys nobilis (Bivalve:Pectinidae) with regard to gender and shell colour显示文摘 | ZHENG Huaiping LIU Helu ZHANG Tao | 2010 | Food Chem2010，122，4： | 1 |
| 9 | Different response to selection in two stock of bay scallop,Argopecten irradians Lamarck(1819)显示文摘 | Zheng Huaiping Zhang Guofan Liu Xiao | 2004 | Journal of Experimental Marine Biology and Ecology2004，，： | 1 |
| 10 | Inbreeding depression for various traits in two stocks of the bay scallop,Argopecten irradians irradians Lamarck(1819)显示文摘 | Zheng Huaiping Zhang Guofan Liu Xiao | | Aquaculture(accepted)0，，： | 1 |
| 11 | Myo-inositol accelerates the metamorphosis from megalopa to crablet of Scylla paramamosain by modulating cuticle decomposition and reconstruction显示文摘The mud crab Scylla paramamosain is a key species in China due to its high nutritional value and great economic worth and has grown in popularity.Myo-inositol can modulate versatile physiological functions in aquatic animals.In the present study,S.paramamosain megalopa were given graded concentrations of myo-inositol(0,1,2,4,and 8 ppm)by water immersion to explore how their metamorphosis would be affected.The results showed that supplementing with myo-inositol remarkably increased transformation and survival rate from megalopa to crablet by at least 1.16 and 1.26 times,respectively.To decipher the molecular mechanism of how myo-inositol increases metamorphosis and survival rate,we further performed transcriptome-based gene expression profiling of both megalopa and crablet treated with myo-inositol.The integrative transcriptome analyses predicted that the differentially expressed genes(DEGs)were significantly enriched in chitinase activity,structural constituent of cuticle,and chitin binding,which are associated with the decomposition and reconstruction of cuticle.qPCR results confirmed that myo-inositol mediated gene expression levels of the above cuticle-related pathways.Considering the importance of the cuticle in exoskeleton formation and molting,it can be concluded that myo-inositol-induced changes in the cuticle decomposition and reconstruction might have accelerated the transformation from megalopa to crablet of S.paramamosain.Besides,numerous DEGs were significantly enriched in protein digestion and absorption,amino sugar and nucleotide sugar metabolism.It implies that myo-inositol may improve survival by regulating energy or nutrient absorption.Additionally,the accelerated metamorphosis by myo-inositol may improve survival from megalopa to crablet of S.paramamosain.Overall,this study will provide the first insights into the underlying molecular mechanisms by which myo-inositol increases metamorphosis and survival. | Wenxiao Cui Hafiz Sohaib Ahmed Saqib Weifeng Gao Ruibo Wang Yang He Yang Yu Zhen Lin Qingyu Zhang Yin Zhang Shengkang Li Huaiping Zheng Yueling Zhang Mhd Ikhwanuddin Hongyu Ma | 2023 | Aquaculture and Fisheries2023，8，6： | 0 |
| 12 | Identification and Characterization of Gene SpDMRT99B and Its Sex-Biased Expression Profile in the Mud Crab,Scylla paramamosain显示文摘The doublesex and mab-3 related transcription factor(DMRT)gene family is conserved from invertebrates to humans.The functions of DMRT are mainly involved in sex development and the formation of many tissues and organs.In this study,a DM(Doublesex/Mab-3-domain gene was identified in the mud crab Scylla paramamosain,and was named SpDMRT99B because of its many similarities to arthropod DMRT99B and phylogenetically close relationship with arthropod DMRT99B.The cDNA of SpDMRT99B gene is 1249 bp in length,encoding 224 amino acids.From 254 bp to 928 bp there is a conserved DM domain.No transmembrane domain was identified.Through multiple amino acid alignment and phylogenetic tree analysis,the closest gene to SpDMRT99B is Eriocheir sinensis DMRT99B,followed by Macrobrachium rosenbergii and Drosophila melanogaster DMRT99B.The expressions of the gene were characterized in different tissues of female and male crabs during early development period of crab individuals,as well as in different development periods of gonads.The results showed that SpDMRT99B gene is significantly highly expressed in testis than in ovary and other tissues.The expression level of SpDMRT99B in testis at different stages is significantly higher than that in ovary,and it is particularly highly expressed in immature testis.In early developmental stages of larvae,the expressions of SpDMRT99B remain at a low level and reach a peak at zoea stage I when the body segments shape up.It is speculated that SpDMRT99B gene might be involved in the gonadal development process and somitogenesis of S.paramamosain. | ZHANG Yin FANG Shaobin LIN Fei LI Shengkang ZHENG Huaiping ZHANG Yueling IKHWANUDDIN Mhd MA Hongyu | 2021 | Journal of Ocean University of China2021，20，6： | 0 |
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