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| 1 | A facile and general method for synthesis of antibiotic-free protein-based hydrogel:Wound dressing for the eradication of drug-resistant bacteria and biofilms显示文摘Antibacterial protein hydrogels are receiving increasing attention in the aspect of bacteria-infected-wound healing. However, bacterial drug resistance and biofilm infections lead to hard healing of wounds, thus the construction of biological agents that can overcome these issues is essential. Here, a simple and universal method to construct antibiotic-free protein hydrogel with excellent biocompatibility and superior antibacterial activity against drug-resistant bacteria and biofilms was developed. The green industrial microbicide tetrakis (hydroxymethyl) phosphonium sulfate (THPS) as cross-linking agent can be quickly cross-linked with model protein bovine serum albumin (BSA) to form antibacterial hydrogel through simple mixing without any other initiators, subsequently promoting drug-resistance bacteria-infected wound healing. This simple gelatinization strategy allows at least ten different proteins to form hydrogels (e.g. BSA, human serum albumin (HSA), egg albumin, chymotrypsin, trypsin, lysozyme, transferrin, myohemoglobin, hemoglobin, and phycocyanin) under the same conditions, showing prominent universality. Furthermore, drug-resistance bacteria and biofilm could be efficiently destroyed by the representative BSA hydrogel (B-Hydrogel) with antibacterial activity, overcoming biofilm-induced bacterial resistance. The in vivo study demonstrated that the B-Hydrogel as wound dressing can promote reepithelization to accelerate the healing of methicillin-resistant staphylococcus aureus (MRSA)-infected skin wounds without inducing significant side-effect. This readily accessible antibiotic-free protein-based hydrogel not only opens an avenue to provide a facile, feasible and general gelation strategy, but also exhibits promising application in hospital and community MRSA disinfection and treatment. | Jiang Ouyang Qingyue Bu Na Tao Mingkai Chen Haijun Liu Jun Zhou Jinggong Liu Bo Deng Na Kong Xingcai Zhang Tianfeng Chen Yihai Cao Wei Tao | 2022 | Bioactive Materials2022，7，12： | 2 |
| 2 | Combustion characteristics and influential factors of isooctane active-thermal atmosphere combustion assisted by two-stage reaction of n -heptane显示文摘 | Xingcai Lu Libin Ji Junjun Ma Xiaoxin Zhou Zhen Huang | 2010 | Combustion and Flame2010，，2： | 1 |
| 3 | Bioresource Upgrade for Sustainable Energy,Environment,and Biomedicine显示文摘We conceptualize bioresource upgrade for sustainable energy,environment,and biomedicine with a focus on circular economy,sustainability,and carbon neutrality using high availability and low utilization biomass(HALUB).We acme energy-efficient technologies for sustainable energy and material recovery and applications.The technologies of thermochemical conversion(TC),biochemical conversion(BC),electrochemical conversion(EC),and photochemical conversion(PTC)are summarized for HALUB.Microalgal biomass could contribute to a biofuel HHV of 35.72 MJ Kg^(-1)and total benefit of 749$/ton biomass via TC.Specific surface area of biochar reached 3000 m^(2)g^(-1)via pyrolytic carbonization of waste bean dregs.Lignocellulosic biomass can be effectively converted into bio-stimulants and biofertilizers via BC with a high conversion efficiency of more than 90%.Besides,lignocellulosic biomass can contribute to a current density of 672 mA m^(-2)via EC.Bioresource can be 100%selectively synthesized via electrocatalysis through EC and PTC.Machine learning,techno-economic analysis,and life cycle analysis are essential to various upgrading approaches of HALUB.Sustainable biomaterials,sustainable living materials and technologies for biomedical and multifunctional applications like nano-catalysis,microfluidic and micro/nanomotors beyond are also highlighted.New techniques and systems for the complete conversion and utilization of HALUB for new energy and materials are further discussed. | Fanghua Li Yiwei Li KSNovoselov Feng Liang Jiashen Meng Shih‑Hsin Ho Tong Zhao Hui Zhou Awais Ahmad Yinlong Zhu Liangxing Hu Dongxiao Ji Litao Jia Rui Liu Seeram Ramakrishna Xingcai Zhang | 2023 | Nano-Micro Letters2023，15，3： | 1 |
| 4 | Auto- ignition and combustion characteristics of n-butanol trig- gered by low- and high-temperature reactions of pre- mixed n-heptane 显示文摘 | Lu Xingcai Yang Zheng Zhou Xiaoxin | 2013 | Fuel2013，112，： | 1 |
| 5 | Auto?ignition and combustion characteristics of n-butanol triggered by low- and high-temperature reactions of premixed n-heptane显示文摘 | Ltl Xingcai Yang Zheng Zhou Xiaoxin | 2013 | Fuel2013，112，： | 1 |
| 6 | Climate change and water security in the northern slope of the Tianshan Mountains显示文摘Water security is under threat worldwide from climate change. A warming climate would accelerate evaporationand cryosphere melting, leading to reduced water availability and unpredictable water supply. However, thewater crisis in the Northern Slope of Tianshan Mountains(NSTM) faces dual challenges because water demandsforfast-growing urban areas have put heavy pressure on water resources. The mountain-oasis-desert system featuresglacier-fed rivers that sustain intensive water use in the oasis and end in the desert as fragile terminal lakes.The complex balance between water conservation and economic development is subtle. This paper investigateschanges in hydroclimatic variables and water security-related issues on the NSTM. The spatiotemporal variationsin glaciers, climatic variables, rivers, lakes and reservoirs, groundwater, surface water, human water use, andstreamflow were analyzed for the past four decades. The results show that temperature in the NSTM exhibitedan apparent upward trend with a more significant warming rate in the higher altitude regions. Glacier massloss and shrinkage was strong. The average annual streamflow increased from 1980-1989 to 2006–2011 at mosthydrological stations. The monthly dynamics of surface water area showed notable variability at both inter-annual and seasonal scales, revealing the impacts of both natural and anthropogenic drivers on surface wateravailability in the region. The terrestrial water storage anomaly showed a decreasing trend, which might berelated to groundwater pumping for irrigation. Human water use for agriculture and industry grew with theincrease in cultivated land area and gross domestic product (GDP). The increased agricultural water use wasstrongly associated with the expansion of oases. It is unclear whether water availability would remain high underfuture climatic and hydrological uncertainties, posing challenges to water management. In the context of rapidurban growth and climate change, balancing water for humans and nature is vital in achieving the SustainableDevelopment Goals (SDGs) in NSTM. This study provides a baseline understanding of the interplay among water,climate change, and socio-economic development in NSTM. It would also shed light on wise water managementunder environmental changes for other rapidly developing mountain-oasis-desert systems worldwide. | Qiuhong Tang Xingcai Liu Yuanyuan Zhou Puyu Wang Zhongqin Li Zhixin Hao Suxia Liu Gang Zhao Bingqi Zhu Xinlin He Fadong Li Guang Yang Li He Haoxin Deng Zongxia Wang Xiang Ao Zhi Wang Paul P.J.Gaffney Lifeng Luo | 2022 | Geography and Sustainability2022，3，3： | 1 |
| 7 | Triple-synergistic MOF-nanozyme for efficient antibacterial treatment显示文摘The abuse of antibiotics makes bacterial infection an increasingly serious global health threat. Reactive oxygen species (ROS) are the ideal alternative antibacterial approach for quick and effective sterilization. Although various antibacterial strategies based on ROS have been developed, many of them are still limited by insufficient antibacterial efficiency. Here, we have developed an acid-enhanced dual-modal antibacterial strategy based on zeolitic imidazolate frameworks-8 (ZIF8) -derived nanozyme. ZIF8, which can release Zn2+, is chosen as the carrier to integrate glucose oxidase (GOx) and gold nanoparticles (Au NPs) which can produce ROS via a cascade catalytic reaction. Thus, the bactericidal capability of ROS and Zn2+ have been integrated. More importantly, gluconic acid, a “by-product” of the catalytic reaction, can generate an acidic environment to promote both the ROS-producing and Zn2+-releasing, enhancing the overall antibacterial performance further. This triple-synergistic strategy exhibits extraordinary bactericidal ability at a low dosage of 4 μg/mL (for S. aureus) and 8 μg/mL (for E. coli), which shows a great potential of MOF-derived nanozyme for efficient bacterial eradication and diverse biomedical applications. | Muxue Wang Xi Zhou Yunhong Li Yuqing Dong Jiashen Meng Shuai Zhang Linbo Xia Zhaozhi He Lei Ren Zhiwei Chen Xingcai Zhang | 2022 | Bioactive Materials2022，7，11： | 1 |
| 8 | The Asymptotic Properties of Scad Penalized Generalized Linear Models with Adaptive Designs显示文摘This paper discusses the asymptotic properties of the SCAD(smoothing clipped absolute deviation)penalized quasi-likelihood estimator for generalized linear models with adaptive designs,which extend the related results for independent observations to dependent observations.Under certain conditions,the authors proved that the SCAD penalized method correctly selects covariates with nonzero coefficients with probability converging to one,and the penalized quasi-likelihood estimators of non-zero coefficients have the same asymptotic distribution they would have if the zero coefficients were known in advance.That is,the SCAD estimator has consistency and oracle properties.At last,the results are illustrated by some simulations. | GAO Qibing ZHU Chunhua DU Xiuli ZHOU Xingcai YIN Dingxin | 2021 | Journal of Systems Science & Complexity2021，34，2： | 0 |
| 9 | Discussion of: ‘A review of distributed statistical inference’显示文摘First of all,we would like to congratulate Dr Gao et al.for their excellent paper,which provides a compre-hensive overview of amounts of existing work on dis-tributed estimation(learning).Different from related work Gu et al.(2019);Liu et al.(2021);Verbraeken et al.(2020)that focus on computing,storage and com-munication architecture,the current paper leverages how to guarantee statistical efficiency of a given dis-tributed method from a statistical viewpoint. | Shaogao Lv Xingcai Zhou | 2022 | Statistical Theory and Related Fields2022，6，2： | 0 |
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