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23篇 您的检索式:作者名="ZIAKA E"
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1Portopulmonary hypertension and serum endothelin levels in hospitalized patients with cirrhosis显示文摘BACKGROUND:Cirrhosis is associated with several extrahepatic manifestations including portopulmonary hypertension (PPHT).Recent data suggest that endothelins (ETs) are related to the pathophysiology of PPHT.The study aimed to measure serum ET levels in hospitalized cirrhotic patients and to determine their association with PPHT and patient outcome.METHODS:Fifty-seven cirrhotic patients [43 males;median age 58 (28-87) years] underwent Doppler echocardiography.Patients with systolic pulmonary arterial pressure ≥40 mmHg and pulmonary acceleration time <100 ms were deemed to have PPHT.ET-1,2,and 3 serum levels were measured with an ELISA assay.All-cause mortality was recorded over a median period of 24 months.RESULTS:Nine out of 57 patients (15.8%) had PPHT.Among various clinical variables,only autoimmune hepatitis was associated with PPHT (OR=11.5;95% CI,1.58-83.4;P=0.01).ET-1 levels [9.1 (1.6-20.7) vs 2.5 (1.4-9.2) pg/mL,P=0.02] and the ET-1/ET-3 ratio [4.73 (0.9-22.4) vs 1.6 (0.3-10.7),P=0.02] were significantly higher in patients with PPHT than in those without.ET-2 and ET-3 levels did not differ between the two groups.There was no difference in survival between the two groups,although ET-1 levels were associated with an adverse outcome in Cox regression analysis (HR=1.11;95% CI,1.02-1.22;P=0.02 per unit increase in ET-1).CONCLUSION:Our data suggest that ET-1 and the ET-1/ET-3 ratio are elevated in patients with PPHT and that ET-1 is associated with a poor outcome irrespective of PPHT.Aristotelis Tsiakalos Gregorios Hatzis Ioannis Moyssakis Aggelos Karatzaferis Panayiotis D Ziakas George E Tzelepis 2011Hepatobiliary & Pancreatic Diseases International2011,10,4:7
2Effect of prophy-lactic lamivudine for chemotherapy-associated hepatitis B reactivation in lymphoma:a meta-analysis of published clinical trials and a decision tree addressing prolonged prophylaxis and maintenance显示文摘Ziakas PD Karsaliakos P Mylonakis E 2009Haematologica2009,94,7:1
3Effect of prophylactic lamivudine for chemotherapy-associated hepatitis B reactivation in lymphoma:a meta-analysis of published clinical trials and a decision tree addressing prolonged prophylaxis and maintenance显示文摘Ziakas PD Karsaliakos P Mylonakis E 2009Haematologica2009,94,7:1
4Effect of prophy-lactic lamivudine for chemotherapy-associated hepatitis B reactiva-tion in lymphoma:a meta-analysis of published clinical trials and adecision tree addressing prolonged prophylaxis and maintenance显示文摘Ziakas PD Karsaliakos P Mylonakis E et ai 2009Haematol2009,94,1:1
5Formulation and preliminary in vivo dog studies of a novel drug delivery system for the treatment of periodontitis显示文摘Kelly H M Deasy P B Ziaka E 2004Int Pharmaceutics2004,274,12:1
6Reduction of the estimated radiation dose and associated patient risk with prospective ECG-gated 256-slice CT coronary angiography显示文摘E P Efstathopoulos N L Kelekis I Pantos E Brountzos S Argentos J Grebá? D Ziaka D G Katritsis I Seimenis 2009Physics in Medicine and Biology2009,,17:1
7Formulation and preliminary in vivo dog studies of a novel drug delivery system for the treatment of periodontitis 显示文摘KELLY HM DEASY PB ZIAKA E 2004Int J Pharm2004,274,12:1
8Effect of prophy-lactic lamivudine for chemotherapy-associated hepatitis B reactiva-tion in lymphoma:a meta-analysis of published clinical trials and adecision tree addressing prolonged prophylaxis and maintenance显示文摘Ziakas PD Karsaliakos P Mylonakis E 2009Haematologia2009,94,7:1
9Effect of prophy-lactic lamivudine for chemotherapy-associated hepatitis B reactivation in lymphoma: a meta-analysis of published clinical trials and a decision tree addressing prolonged prophylaxis and maintenance 显示文摘Ziakas PD Karsaliakos P Mylonakis E 2009Haematologica2009,94,7:1
10Effect of prophylactic lamivudine for chemotherapy-associated hepatitis B reactivation in lymphoma:a meta-analysis of published clinical trials and a decision tree addressing prolonged prophylaxis and maintenance显示文摘Ziakas PD Karsaliakos P Mylonakis E 2009Haematologica2009,94,7:1
11Effect of prophylactic lamivudine for chemotherapy-associated hepatitis B reactivation in lymphoma:a meta-analysis of published clinical trials and a decision tree addressing prolonged prophylaxis and maintenance显示文摘ZIAKAS P D KARSALIAKOS P MYLONAKIS E 2009Haematologica2009,94,7:1
12Membranous glomemlonephritis in chronic lymphocytic leukemia显示文摘Ziakas PD Giannouli S Psimenou E 0,,03:1
13Formulation and preliminary in vivo dog studies of a novel drug delivery system for the treatment of periodontitis 显示文摘Kelly H M Deasy P B Ziaka E 2004Int J Pharm2004,274,12:1
14Systemic antifungalprophylaxis after hematopoietic stem cell transplantation:aweZa-analysis显示文摘Ziakas PD Kourbeti IS Mylonakis E 2014Clin Ther2014,36,2:1
15Lupus thrombocytopenia:clinical implications and prognostic significance显示文摘Ziakas PD Giannouli S Zintzaras E 2005Ann Hheum Dis2005,64,9:1
16Formulation and prelimi-nary in vivo dog studies of a novel drug delivery system for thetreatment of periodontitis 显示文摘Kelly HM Deasy PB Ziaka E 2004Int J Pharrti2004,274,2:1
17Formulation and preliminary in vivo dog studies of a novel drug delivery system for the treatment of periodontitis显示文摘Kelly HM Deasy PB Ziaka E 2004Int J Pharm2004,274,12:1
18Formulation and preliminary in vivo dog studies of a novel drug delivery system for the treatment of periodontitis显示文摘 DEASY P B ZIAKA E 2004International Journal of Pharmaceutics2004,274,:1
19Lupus thrombocytopenia: clinical implications and prognostic significance显示文摘Ziakas PD Giannouli S Zintzaras E 2005Ann Rheum Dis2005,64,9:1
20Effect of prophylactic lami- vudine for chemotherapy - associated hepatitis B reactivation in lymphoma : a meta - analysis of published clinical trials and a deci- sion tree addressing prolonged prophylaxis and maintenance 显示文摘Ziakas D Karsaliakos P Mylonakis E 2009ttaematologiea2009,94,7:1
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