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| 1 | High-static-low-dynamic-stiffness vibration isolation enhanced by damping nonlinearity显示文摘High-static-low-dynamic-stiffness(HSLDS) nonlinear isolators have proven to have an advantage over linear isolators, because HSLDS nonlinear isolators allow low-frequency vibration isolation without compromising the static stiffness. Previously, these isolators have generally been assumed to have linear viscous damping, degrading the performance of the isolator at high frequencies. An alternative is to use nonlinear damping, where the nonlinear behavior is achieved by configuring linear dampers so they are orthogonally aligned to the excitation direction. This report compares the performances of single-stage and two-stage isolators with this type of damping with the corresponding isolators containing only linear viscous damping. The results show that both isolators with linear viscous damping and nonlinear damping reduce the transmissibility around the resonance frequencies, but the results show that the isolators with nonlinear damping perform better at high frequencies. | LU ZeQi BRENNAN Michael DING Hu CHEN LiQun | 2019 | Science China(Technological Sciences)2019，62，7： | 5 |
| 2 | Nonlinear energy harvesting based on a modified snap-through mechanism显示文摘A modified snap-through mechanism is used in an electromagnetic energy harvester to improve its effectiveness. It mainly comprises three springs that are configured so that the potential energy of the system has two stable equilibrium points. In particular, the small vibration behavior of the harvester around one of the equilibriums is of interest. A multi-scale method(MSM) is used to analyze the frequency response curve. Two snap-through mechanisms are considered. One has both horizontal and vertical springs. The other has only horizontal springs. The frequency response curves of these two classes are compared under the same excitation and electric loading conditions. The latter exhibits more bending of the frequency response curve than the former one. The results are also validated by some numerical work. The averaged power subject to the Gaussian white noise is calculated numerically, and the results demonstrate that bi-stable energy harvesting with only horizontal springs can outperform the mechanism with both horizontal and vertical springs for the same distance between two equilibriums. | Zeqi LU Ke LI Hu DING Liqun CHEN | 2019 | Applied Mathematics and Mechanics(English Edition)2019，40，1： | 3 |
| 3 | Isotoosendanin exerts inhibition on triple-negative breast cancer through abrogating TGF-β-induced epithelial—mesenchymal transition via directly targeting TGFβR1显示文摘As the most aggressive breast cancer,triple-negative breast cancer(TNBC) is still incurable and very prone to metastasis.The transform growth factor β(TGF-β)-induced epithelial—mesenchymal transition(EMT) is crucially involved in the growth and metastasis of TNBC.This study reported that a natural compound isotoosendanin(ITSN) reduced TNBC metastasis by inhibiting TGF-β-induced EMT and the formation of invadopodia.ITSN can directly interact with TGF-β receptor type-1(TGFβR1) and abrogated the kinase activity of TGFβR1,thereby blocking the TGF-β-initiated downstream signaling pathway.Moreover,the ITSN-provided inhibition on metastasis obviously disappeared in TGFβR1-overexpressed TNBC cells in vitro as well as in mice bearing TNBC cells overexpressed TGFβR1.Furthermore,Lys232 and Asp351 residues in the kinase domain of TGFβR1 were found to be crucial for the interaction of ITSN with TGFβR1.Additionally,ITSN also improved the inhibitory efficacy of programmed cell death 1 ligand 1(PD-L1) antibody for TNBC in vivo via inhibiting the TGF-β-mediated EMT in the tumor microenvironment.Our findings not only highlight the key role of TGFβR1 in TNBC metastasis,but also provide a leading compound targeting TGFβR1 for the treatment of TNBC metastasis.Moreover,this study also points out a potential strategy for TNBC treatment by using the combined application of anti-PD-L1 with a TGFβR1 inhibitor. | Jingnan Zhang Ze Zhang Zhenlin Huang Manlin Li Fan Yang Zeqi Wu Qian Guo Xiyu Mei Bin Lu Changhong Wang Zhengtao Wang Lili Ji | 2023 | Acta Pharmaceutica Sinica B2023，13，7： | 1 |
| 4 | Chemical Fertilizer Reduction and High Yield Cultivation Technique for Peanut显示文摘For a long time,the amount of fertilizer applied to peanuts in China has been much higher than that of other main peanut producing countries.At the same time of increasing production,chemical fertilizers have also brought many adverse effects,which have brought potential threats to the sustainable development of peanut production.While continuously increasing the yield,reducing the amount of chemical fertilizer has become an urgent problem to be solved in peanut production of China.Based on the research results of our team,this paper appropriately absorbed the latest research progress of chemical fertilizer reduction in related fields,and established the cultivation technique for peanut fertilizer reduction and high yield under different cultivation modes,to realize the synchronization of fertilizer reduction and yield increase for peanut production.The technique includes two parts:common technology and different cultivation mode fertilization schemes.The former includes crop rotation,proper deep tillage,application of organic fertilizer,selection of nutrient-efficient varieties,topdressing of foliar fertilizer,etc.,the latter includes film mulching spring peanut,continuous cropping field,acidified soil,peanuts interplanting with wheat,and summer direct sowing,etc.This technique provides a technical support for the chemical fertilizer reduction of peanut production in China. | Yaping ZHENG Shifu WANG Zulin ZHENG Lili WANG Chunxiao WANG Zeqi LU Wei JIANG Hongwei ZANG Yongmei ZHENG | 2019 | Asian Agricultural Research2019，11，10： | 1 |
| 5 | High-yield and High-efficiency Standardized Cultivation Technique for Wheat Interplanting with Peanuts显示文摘Through wheat interplanting with peanuts,it is able to make full use of the light and heat resources in the growing season to achieve high yield of both wheat and peanuts in two seasons of one year.Wheat interplanting with peanuts is one of the main cultivation methods of wheat and oil crop double cropping system,and has very broad development prospects in the Huang-Huai-Hai region.This paper summarized high-yield the high-efficiency and standardized cultivation techniques for wheat interplanting with peanuts,including crop rotation,proper deep ploughing,balanced fertilization,rational matching of fine varieties,interplanting at suitable time,sowing according to certain specification,and enhancing the field management.This can be used as reference for high-yield and high-efficiency standardized cultivation technique for wheat interplanting with peanuts. | Yaping ZHENG Zulin ZHENG Lili WANG Chunxiao WANG Zeqi LU Wei JIANG Hongwei ZANG Hao FENG Yongmei ZHENG Caibin WANG | 2019 | Asian Agricultural Research2019，11，11： | 0 |
| 6 | An Investigation into the Isolation Performance of Mono-and Bi-stable Systems显示文摘由对改进隔离表演的需要激发了,许多研究研究与非线性的特征在隔离乾上被执行了。基于他们的阶段肖像的形状,如此的设备能作为也被设置单稳态或双稳态的隔离乾。这篇论文集中于在一样的刺激下面调查这二个班的相对表演。力量能递送被用来测量隔离表演,它以播送力量的比率的 RMS 被定义到刺激力量。当系统受到泛音刺激时,在隔离的力量能递送的最大的减小用伪变化,这被发现 -- 零僵硬被完成。当系统受到随机的刺激时,它有伪的一样的效果 -- 零僵硬。进一步,最佳抑制能与僵硬被改变并且有最小的价值。 | Zeqi Lu Tiej un Yang Michael J. Brennan Xinhui Li Zhigang Liu | 2014 | Journal of Marine Science and Application2014，13，3： | 0 |
| 7 | High-Risk LEO Satellite Network Path Detection Based on Spatial and Temporal Delay Anomaly Analysis显示文摘The gradual deployment of Low-Earth Orbit(LEO)mega constellations with inter-satellite links(ISLs)promises ubiquitous,low-latency,and high-throughput satellite network services.However,networked LEO satellites with ISLs are also at risk of routing attacks such as hijacking.Existing defenses against route hijacking in terrestrial networks can hardly work for the LEO satellite network due to its high spatiotemporal dynamics.To deal with it,we propose RPD,a high-risk routing path detection method for LEO mega-constellation networks.RPD detects abnormal high-risk LEO network paths by checking the consistency between the path delay and the geographical distance.This is efficiently achieved by combining in-band measurements and out-of-band statistical processing to detect the anomaly of the clustering feature in the reference delay matrix.RPD avoids the recalculation of the header cryptographic marks when the handover occurs,thus greatly reducing the cost and improving the performance of highrisk path detection.Experiments showed that the proposed RPD mechanism achieves an average detection accuracy of 91.64%under normal network conditions,and maintain about 89%even when congestion occurs in multiple areas of the network and measurement noise is considered.In addition,RPD does not require any cryptographic operation on the intermediate node,only minimal communication cost with excellent scalability and deployability. | Tianyu Zhang Hewu Li Jun Liu Lu Lu Qian Wu Shaowen Zheng Zeqi Lai Yuanjie Li | 2023 | China Communications2023，20，7： | 0 |
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