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| 1 | Two gap-free reference genomes and a global view of the centromere architecture in rice显示文摘Rice(Oryza sativa),a major staple throughout the world and a model system for plant genomics and breeding,was the first crop genome sequenced almost two decades ago.However,reference genomes for all higher organisms to date contain gaps and missing sequences.Here,we report the assembly and analysis of gap-free reference genome sequences for two elite O.sativa xian/indica rice varieties,Zhenshan 97 and Minghui 63,which are being used as a model system for studying heterosis and yield.Gap-free reference genomes provide the opportunity for a global view of the structure and function of centromeres.We show that all rice centromeric regions share conserved centromere-specific satellite motifs with different copy numbers and structures.In addition,the similarity of CentO repeats in the same chromosome is higher than across chromosomes,supporting a model of local expansion and homogenization.Both genomes have over 395 non-TE genes located in centromere regions,of which∼41%are actively transcribed.Two large structural variants at the end of chromosome 11 affect the copy number of resistance genes between the two genomes.The availability of the two gap-free genomes lays a solid foundation for further understanding genome structure and function in plants and breeding climate-resilient varieties. | Jia-Ming Song Wen-Zhao Xie Shuo Wang Yi-Xiong Guo Dal-Hoe Koo Dave Kudrna Chenbo Gong Yicheng Huang Jia-Wu Feng Wenhui Zhang Yong Zhou Andrea Zuccolo Evan Long Seunghee Lee Jayson Talag Run Zhou Xi-Tong Zhu Daojun Yuan Joshua Udall Weibo Xie Rod AWing Qifa Zhang Jesse Poland Jianwei Zhang Ling-Ling Chen | 2021 | Molecular Plant2021，14，10： | 9 |
| 2 | Plateletderived growth factor -producing cells immortalized from rat mesencephalon with SV40 large T antigen transduced by an AAV vector显示文摘 | Phillips AW Zhang P Truckenmiller ME | 2003 | Restor Neurol Neurosci2003，21，12： | 1 |
| 3 | Escherichia coli harboring Shiga toxin 2 gene variants: frequency and association with clinical symptoms显示文摘 | Friedrich AW Bielaszewska M Zhang WL | 2002 | J Infect Dis2002，185，1： | 1 |
| 4 | Effects of transcranial direct current stimulation on hemichannel pannexin-1 and neural plasticity in rat model of cerebral infarction 显示文摘 | Jiang T Xu RX Zhang AW | 2012 | Neuroscienee2012，226，： | 1 |
| 5 | Safety and tolerability of early noninvasiveventilatory correction using bilevel positive air-way pressure in acute ischemic stroke 显示文摘 | Tsivgoulis G Zhang Y Alexandrov AW | 2011 | Stroke2011，42，4： | 1 |
| 6 | Effects of transcranial direct current stimulation on hemichannel pannexin-1 and neural plasticity in rat model of cerebral infarction 显示文摘 | Jiang T Xu RX Zhang AW | 2012 | Neuroscience2012，13，226： | 1 |
| 7 | USP22,an hSAGA subunit and potential cancer stem cell marker,reverses the polycomb-catalyzed ubiquitylation of histone H2A显示文摘 | Zhang XY Pfeiffer HK Thorne AW | | 0，，11： | 1 |
| 8 | USP22,an hSAGA subunit and potential cancer stem cell marker,reverses the polycomb-catalyzed ubiquityl-ation of histone H2A显示文摘 | Zhang XY Pfeiffer HK Thorne AW McMahon SB | 2008 | Cell Cycle2008，7，11： | 1 |
| 9 | Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (MDA-7/IL-24): Biologic outcome in advanced cancer patients 显示文摘 | Tong AW Nemunaitis J Su D Zhang Y Cunningham C Senzer N | 2005 | MolTher2005，11，1： | 1 |
| 10 | Exploring syntactic struetured feature over parse trees for relation extraetion using kernel methods 显示文摘 | Zhang Min Zhong Guo - along Aw Aiti | 2008 | Information Processing and Management2008，44，： | 1 |
| 11 | Persistence of typespecific human papillomavirus infection among cytologically normal women显示文摘 | Hsing AW Schiffman M Zhang T | 1994 | J Infect Dis1994，170，2： | 1 |
| 12 | Reactive oxygen species generation by seminal Cells during cyropreservation显示文摘 | Wang AW Zhang H Ikemoto I | 1997 | Urology1997，49，6： | 1 |
| 13 | Preparation and characterization of nano-mag- netoparticles with radiofrequency-induced hyperthermia for cancer treatment 显示文摘 | Fan XS Zhang DS Zheng J Gu N Ding AW Jia XP | 2006 | J Biomed Eng2006，23，4： | 1 |
| 14 | Reactive oxygen species generation by seminal cells during cryopreservation显示文摘 | Wang AW Zhang H Ikemoto I | 1997 | Urology1997，，49： | 1 |
| 15 | The potential use of al- logeneic platetet rich plasma for large bone defect treatment- immunogenicity and defect healing efficacy显示文摘 | Zhang ZY H uang AW Fan J J | 2013 | Cell Trans- plant2013，22，1： | 1 |
| 16 | The rapid determination of γ-aminobutyric acid显示文摘 | Zhang G Bown AW | 1997 | Phytochemistry1997，44，6： | 1 |
| 17 | Propofol dilates human cerebral veins显示文摘 | Gekb AW Hamilton JT Zhang C | 1993 | Anesthesiology1993，79，3： | 1 |
| 18 | Orthogonal arraydesign for antidepressant compatibility of poly-saccharides from Banxia Houpo Decoction, a tra-ditional Chinese herb prescription in the mousemodels of depression 显示文摘 | Yi LT Zhang L Ding AW | 2009 | Arch Pharm Res2009，32，10： | 1 |
| 19 | Zircons from rodingite in the Western Tianshan serpentinite complex:Mineral chemistry and U-Pb ages define nature and timing of rodingitization显示文摘 | Li Xuping Zhang Lifei Simon AW Song Biao Liu Xiaoming | | 0，，： | 1 |
| 20 | LC-DAD-ESI-MS-MS Separation and Chemical Characterization of the Inflammatory Fraction of the Roots of Euphorbia kansui 显示文摘 | Zhang L Shu XY Ding AW | 2009 | Chromatographia2009，70，： | 1 |
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