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| 1 | In vivo theranostics with near-infraredemitting carbon dots—highly efficient photothermal therapy based on passive targeting after intravenous administration显示文摘Carbon dots that exhibit near-infrared fluorescence(NIR CDs)are considered emerging nanomaterials for advanced biomedical applications with low toxicity and superior photostability and targeting compared to currently used photoluminescence agents.Despite progress in the synthesis of NIR CDs,there remains a key obstacle to using them as an in vivo theranostic agent.This work demonstrates that the newly developed sulfur and nitrogen codoped NIR CDs are highly efficient in photothermal therapy(PTT)in mouse models(conversion efficiency of 59%)and can be readily visualized by photoluminescence and photoacoustic imaging.The real theranostic potential of NIR CDs is enhanced by their unique biodistribution and targeting.Contrary to all other nanomaterials that have been tested in biomedicine,they are excreted through the body’s renal filtration system.Moreover,after intravenous injection,NIR CDs are accumulated in tumor tissue via passive targeting,without any active species such as antibodies.Due to their accumulation in tumor tissue without the need for intratumor injection,high photothermal conversion,excellent optical and photoacoustic imaging performance,and renal excretion,the developed CDs are suitable for transfer to clinical biomedical practice. | Xin Bao Ye Yuan Jingqin Chen Bohan Zhang Di Li Ding Zhou Pengtao Jing Guiying Xu Yingli Wang Kateřina Holá Dezhen Shen Changfeng Wu Liang Song Chengbo Liu Radek Zbořil Songnan Qu | 2018 | Light(Science & Applications)2018，7，1： | 13 |
| 2 | Experimental and theoretical studies of scuffing behavior in piston-pin/piston contacts显示文摘A bench rig was built and used to study the scuffing mechanisms and the effects of sur-face roughness, clearance, and groove on scuffing in piston-pin/bore contacts for dynamic loadsand an oscillatory rotation. The experimental results show that the deterioration of the surfaceshear strength by fatigue cracks appears to contribute to the final scuffing, and the effects of thebore surface roughness and groove on the scuffing behavior are more significant than the clear-ance. A macro-micro approached scuffing model and a criterion for scuffing failure were developedappearing to be justifiable for the practical design and analysis of piston pin/bore bearings. | ZHANG Chao CHENG Herbert S. WANG Qian Center for Surface Engineering and Tribology, Department of Mechanical Engineering, Northwestem University Evanston, IL 60201, USA | 2001 | Science China Mathematics2001，44，S1： | 2 |
| 3 | Loss of organic anion transporting polypeptide 1 al increases deoxycholic acid absorption in mice by increasing intestinal permeability 显示文摘 | Zhang Y Csanaky IL Lehman - McKeeman LD | 2011 | Toxicol Sci2011，124，2： | 1 |
| 4 | Near room temperature magnetocaloric effect in FeMnPBC metallic glasses with tunable Curie temperature 显示文摘 | Zhang H Y Li IL Xu T | 2013 | J Magn Magn Mater2013，347，： | 1 |
| 5 | Study of Dynamic Robustness of Servo Control System on a Water Press显示文摘The reliability and robustness of the electro-hydraulic servo control system for heavy-duty forging machine play an important role in forging processes. A mathematic model of 50 MN water press for free forging was created in this research. The dynamic robust compensator integrating with PID control method is designed and applied to the mathematical model simulation. The simulated results approved that the dynamic robust compensator application restrains interference from extra load and improves the electro-hydraulic position servo control system accuracy and stability. | KONG Xiangdong1,YAO Jing1,GAO Yingjie1,ZHANG Qin2 (1.Yanshan University,Qinhuangdao 066004,China 2.University Illinois of Urbana-Champaign,Urbana,IL,USA) | 2006 | 武汉理工大学学报2006，28，S1： | 1 |
| 6 | Temporal expression of hypoxia-regulated genes is associated with early changes in redox status in irradiated lung显示文摘 | JACKSON IL ZHANG X HADLEY C | 2012 | Free Radie Bioi Med2012，53，2： | 1 |
| 7 | Temporal expression of hypoxia-regulated genes is associated with early changes in redox status in irradiated lung 显示文摘 | Jackson IL Zhang X Hadley C | 2012 | Free Radic Biol Med2012，53，： | 1 |
| 8 | Effects of vacuum and microwave freeze drying on microstructure and quality of potato slices 显示文摘 | Wang IL Zhang M Mujumdar A S | 2010 | Journal of Food Engineering2010，101，2： | 1 |
| 9 | Palmitic acid induces production of proinflammatory cytokines interleukin-6, interleukin-ll3, and tumor necrosisfactor-ct via a NF-KB-dependent mechanism in HaCaT keratinocytes显示文摘 | Zhou B IL Zhang J A Zhang Q | 2013 | Mediators of Inflammation2013，2013，： | 1 |
| 10 | Engineering of hollow polymeric nanosphere-supported imidazolium-based ionic liquids with enhanced antimicrobial activities显示文摘The design of stable,efficient and processable bactericidal materials represents a significant challenge for combating multidrugresistant bacteria in a variety of engineering fields.Herein,we report a facile strategy for the preparation of hollow polymeric nanosphere(HPN)-supported imidazolium-based ionic liquids(denoted as HPN-ILs)with superior antimicrobial activities.HPNILs were tailored by moderate Friedel−Crafts polymerization followed by the sequential covalent bonding of imidazole and bromoalkene.The resultant HPN-ILs have uniform hollow spherical morphology,an adequate surface area,and excellent physicochemical stability.Furthermore,they are highly active against both Gram-positive and Gram-negative bacteria and exhibit typical time/dosage-dependent antibacterial activities.The rational combination of porous HPNs and antibacterial ILs to generate an all-in-one entity may open new avenues for the design and fabrication of efficient bacteriostatic agents.Moreover,HPN-ILs have good biocompatibility and can also be loaded onto diverse matrices,and thus could extend their practical bactericidal application in the potential biomedical-active field. | Yu Zhang Shuwei Li Yixin Xu Xinyun Shi Mingxin Zhang Yingning Huang Ying Liang Yaqiong Chen Wanli Ji Jung Rae Kim Wenliang Song Deng-Guang Yu Il Kim | 2022 | Nano Research2022，15，6： | 1 |
| 11 | Control of Mechanical Properties According to Content Ratio of Copper Coated Carbon Nanotubes in Alumimum Composites显示文摘 | Jae Deuk Kim Ju Hyung Kim Xiao Hui Zhang Jung Hyun Park Joo Ho Cha Seung Il Jung | 2012 | Journal of Chemistry and Chemical Engineering2012，6，5： | 1 |
| 12 | A finite ele- ment model ofregion - specific response for mild diffuse brain injury显示文摘 | Fijalkowski IL Yoganaadaa N Zhang J | 2009 | Slapp Car Crash J2009，53，： | 1 |
| 13 | High-level secretory expression, purification and characterization of Ailuropoda melanoleuca growth hormone in Pichia pastoris 显示文摘 | Xu Q Wu X Hou R Liao M Il KH Shou J Bian H Han N Pan J Zhang Z Zhu M 2008 | 2008 | Protein Expr Purif2008，60，2： | 1 |
| 14 | 显示文摘 | Duerr RH Barmada MM Zhang IL | 2000 | Am J Hum Genet2000，66，6： | 1 |
| 15 | A simple surface conductance model to estimate regional evaporation using MODIS leaf area index and the Penman-Monteith equation显示文摘 | Letming IL Zhang Y Q Rajaud A | 2008 | Water Resources Research2008，44，10： | 1 |
| 16 | A genome-wide survey of alternative translational initiation events in Homo sapiens显示文摘Alternative translational initiation is an important mechanism to increase the diversity of gene products. Although some of alternative translational initiation events have been reported, such information remains anecdotal and does not allow for any generalizations. The number of the known alternative translational initiation genes is so few that we know little about its mechanism. There is a great demand to discover more alternative translational initiation genes. However, it is arduously time-consuming to discover novel alternative translational initiation genes by the experimental method. Therefore we systematically analyzed protein sequences available in public database and predicted 1237 protein clusters as potential alternative translational initiation events. We concluded that about 8%—10% of human genes have alternative translational initiation sites. The results significantly increased the number of alternative translation initiation events and indicated that alternative translation initiation is an important and general regulation mechanism in the cellular process. | ZHANG Jing1, CAI Jun2 & LI YanDa1 1 Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing 100084, China 2 Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, 61801,USA | 2007 | Science China(Life Sciences)2007，50，3： | 0 |
| 17 | DIASTEREOSELECTIVITY OF ALLYBORATION OF ALDEHYDES显示文摘Reaction of(Z)-Crotyldiisopinocampheylborane with a series of alde-hydes have been examined,and the ratio of erythro to threo products varies fr-om 20:1 to 1:1.The results are discussed in detail. | Xiao An Zhang (Dept.of Chemistry,Northwestern University,Evanston,IL,USA) | 1991 | Chinese Chemical Letters1991，2，2： | 0 |
| 18 | Dissolution of TiO_(2) and TiN inclusions in CaO–SiO_(2)–B_(2)O_(3)-based fluorine-free mold flux显示文摘Mold flux serves the crucial metallurgical function of absorbing inclusions, directly impacting the smoothness of the casting process as well as the cast slab quality. In this study, the dissolution behavior and mechanism of Ti O_(2)and Ti N inclusions in molten Ca O–Si O_(2)–B_(2)O_(3)-based fluorine-free mold flux were explored by in situ single hot thermocouple technology combined with X-ray photoelectron spectroscopy.The results showed that Ti O_(2) inclusions are effectively dissolved by the molten slag within 76 s, during which the original octahedral [Ti O_(6)]^(8-)structures are destroyed and convert to the networker tetrahedral [Ti O_(4)]^(4-)structures. However, the dissolution rate is much lower for Ti N inclusions than for Ti O_(2)inclusions. This can be attributed to the fact that the Ti N particles need to be oxidized and then dissolved in the molten slag to form tetrahedral [Ti O4]4-and octahedral [Ti O_(6)]^(8-)structures during the Ti N inclusion dissolution process, which is accompanied by the generation of a large amount of N_(2)gas. Moreover, Ca Ti O_(3)crystals tend to nucleate and grow on bubble surfaces with sufficient octahedral [Ti O_(6)]^(8-)structures and Ca^(2+)ions, eventually resulting in the molten slag being in a solid–liquid mixed state. | Dawei Cai Li Zhang Wanlin Wang Lei Zhang Il Sohn | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，9： | 0 |
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