|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function显示文摘Exosomes are 40–100 nm nano-sized vesicles that are released from many cell types into the extracellular space. Such vesicles are widely distributed in various body fluids. Recently,m RNAs and micro RNAs(mi RNAs) have been identified in exosomes, which can be taken up by neighboring or distant cells and subsequently modulate recipient cells. This suggests an active sorting mechanism of exosomal mi RNAs, since the mi RNA profiles of exosomes may differ from those of the parent cells. Exosomal mi RNAs play an important role in disease progression, and can stimulate angiogenesis and facilitate metastasis in cancers. In this review, we will introduce the origin and the trafficking of exosomes between cells, display current research on the sorting mechanism of exosomal mi RNAs, and briefly describe how exosomes and their mi RNAs function in recipient cells.Finally, we will discuss the potential applications of these mi RNA-containing vesicles in clinical settings. | Jian Zhang Sha Li Lu Li Meng Li Chongye Guo Jun Yao Shuangli Mi | 2015 | Genomics, Proteomics & Bioinformatics2015，13，1： | 162 |
| 2 | Prevalence of minimal hepatic encephalopathy and quality of life evaluations in hospitalized cirrhotic patients in China显示文摘AIM:To investigate the prevalence of minimal hepatic encephalopathy(MHE)and to assess corresponding health-related quality of life(HRQoL)in hospitalized cirrhotic patients in China.METHODS:This multi-center cross-sectional study included 16 teaching hospitals,which were members of 'Hepatobiliary Cooperation Group,Society of Gastroenterology,Chinese Medical Association',from different areas of China carried out between June and October in 2011.All the eligible hospitalized cirrhotic patients(n = 538)were required to complete triplicate number connection tests combined with one digit symbol test for diagnosing MHE.Patients' clinical examination data were complemented by a modified questionnaire assessing HRQoL.Written informed consent was obtained from each patient.RESULTS:Male was predominant(68.6%)in 519 patients who met the criteria of the study,with a mean age of 49.17 ± 11.02 years.The most common cause of liver cirrhosis was chronic hepatitis B(55.9%).The prevalence of MHE was 39.9% and varied by ChildPugh-Classification score(CPC-A:24.8%,CPC-B:39.4% and CPC-C:56.1%,P < 0.01).MHE(P < 0.01)and higher CPC scores(P < 0.01)were associated with a high HRQoL scores(reflecting poorer quality of life).The prevalence of MHE was proportionate to CPC(P = 0.01)and high quality of life scores(P = 0.01).CONCLUSION:Hospitalized cirrhotic patients have a high prevalence of MHE that is proportionate to the degree of liver function and HRQoL impairment. | Ji-Yao Wang Ning-Ping Zhang Bao-Rong Chi Yu-Qing Mi Li-Na Meng Ying-Di Liu Jiang-Bin Wang Hai-Xing Jiang Jin-Hui Yang Yun Xu Xiao Li Jian-Ming Xu Guo Zhang Xin-Min Zhou Yu-Zheng Zhuge De-An Tian Jin Ye Yu-Lan Liu | 2013 | World Journal of Gastroenterology2013，19，30： | 64 |
| 3 | Controlled attenuation parameter for non-invasive assessment of hepatic steatosis in Chinese patients显示文摘AIM:To evaluate the performance of a novel non-invasive controlled attenuation parameter(CAP)to assess liver steatosis.METHODS:This was a multi-center prospective cohort study.Consecutive patients(aged≥18 years)who had undergone percutaneous liver biopsy and CAP measurement were recruited from three Chinese liver centers.Steatosis was categorized as S0:<5%;S1:5%-33%;S2:34%-66%;or S3:≥67%,according to the nonalcoholic fatty liver disease(NAFLD)activity score.The FibroScan?502 equipped with the M probe(Echosens,Paris,France)was used to capture both CAP and liver stiffness measurement values simultaneously.Receiver operating characteristic curves were plotted,and the areas under the curves were calculated to determine the diagnostic efficacy.The accuracy of the CAP values at the optimal thresholds was defined by maximizing the sum of sensitivity and specificity(maximum Youden index).RESULTS:A total of 152 patients were recruited,including 52(34.2%)patients with NAFLD and 100(65.8%)with chronic hepatitis B(CHB)virus infection.After adjustment,the steatosis grade(OR=37.12;95%CI:21.63-52.60,P<0.001)and body mass index(BMI,OR=6.20;95%CI:2.92-9.48,P<0.001)were found independently associated with CAP by multivariate linear regression analysis.CAP was not influenced by inflammation,fibrosis or aetiology.The median CAP values and interquartile ranges among patients with S0,S1,S2 and S3 steatosis were 211(181-240)dB/m,270(253-305)dB/m,330(302-360)dB/m,and 346(313-363)dB/m,respectively.The cut-offs for the CAP values in all patients with steatosis≥5%,≥34%and≥67%were 253 dB/m,285 dB/m and 310 dB/m,respectively.The areas under the curves were 0.92,0.92and 0.88 for steatosis≥5%,≥34%and≥67%,respectively.No significant differences were found in the CAP values between the NAFLD group and the CHB group in each steatosis grade.CONCLUSION:CAP appears to be a promising tool for the non-invasive detection and quantification of hepatic steatosis,but is limited by BMI. | Feng Shen Rui-Dan Zheng Yu-Qiang Mi Xiao-Ying Wang Qin Pan Guang-Yu Chen Hai-Xia Cao Ming-Li Chen Liang Xu Jian-Neng Chen Yi Cao Rui-Nan Zhang Lei-Ming Xu Jian-Gao Fan | 2014 | World Journal of Gastroenterology2014，20，16： | 55 |
| 4 | Ideotype root architecture for efficient nitrogen acquisition by maize in intensive cropping systems显示文摘The use of nitrogen(N) fertilizers has contributed to the production of a food supply sufficient for both animals and humans despite some negative environmental impact.Sustaining food production by increasing N use efficiency in intensive cropping systems has become a major concern for scientists,environmental groups,and agricultural policymakers worldwide.In high-yielding maize systems the major method of N loss is nitrate leaching.In this review paper,the characteristic of nitrate movement in the soil,N uptake by maize as well as the regulation of root growth by soil N availability are discussed.We suggest that an ideotype root architecture for efficient N acquisition in maize should include(i) deeper roots with high activity that are able to uptake nitrate before it moves downward into deep soil;(ii) vigorous lateral root growth under high N input conditions so as to increase spatial N availability in the soil;and(iii) strong response of lateral root growth to localized nitrogen supply so as to utilize unevenly distributed nitrate especially under limited N conditions. | MI GuoHua,CHEN FanJun,WU QiuPing,LAI NingWei,YUAN LiXing & ZHANG FuSuo* Key Laboratory of Plant Nutrition,MOA Key Laboratory of Plant-Soil Interaction,MOE College of Resources and Environmental Science,China Agricultural University,Beijing 100193,China | 2010 | Science China(Life Sciences)2010，53，12： | 35 |
| 5 | Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients显示文摘The novel contagious primary atypical pneumonia epidemic,which broke out in Wuhan,China,in December 2019,is now formally called Coronavirus Disease 2019(COVID-19),with the causative virus named as Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2).1,2 Recent studies have shown that in addition to dyspnea,hypoxemia,and acute respiratory distress,lymphopenia,and cytokine release syndrome are also important clinical features in patients with severe SARS-CoV-2 infection.3 This suggests that homeostasis of the immune system plays an important role in the development of COVID-19 pneumonia. | Hong-Yi Zheng Mi Zhang Cui-Xian Yang Nian Zhang Xi-Cheng Wang Xin-Ping Yang Xing-Qi Dong Yong-Tang Zheng | 2020 | Cellular & Molecular Immunology2020，17，5： | 38 |
| 6 | Evaluation of the yield and nitrogen use efficiency of the dominant maize hybrids grown in North and Northeast China显示文摘Breeding high-yielding and nutrient-efficient cultivars is one strategy to simultaneously resolve the problems of food security,resource shortage,and environmental pollution.However,the potential increased yield and reduction in fertilizer input achievable by using high-yielding and nutrient-efficient cultivars is unclear.In the present study,we evaluated the yield and nitrogen use efficiency(NUE) of 40 commercial maize hybrids at five locations in North and Northeast China in 2008 and 2009.The effect of interaction between genotype and nitrogen(N) input on maize yield was significant when the yield reduction under low-N treatment was 25%-60%.Based on the average yields achieved with high or low N application,the tested cultivars were classified into four types based on their NUE:efficient-efficient(EE) were efficient under both low and high N inputs,high-N efficient(HNE) under only high N input,low-N efficient(LNE) under only low N input,and nonefficient-nonefficient under neither low nor high N inputs.Under high N application,EE and HNE cultivars could potentially increase maize yield by 8%-10% and reduce N input by 16%-21%.Under low N application,LNE cultivars could potentially increase maize yield by 12%.We concluded that breeding for N-efficient cultivars is a feasible strategy to increase maize yield and/or reduce N input. | CHEN FanJun FANG ZenGuo GAO Qiang YE YouLiang JIA LiangLiang YUAN LiXing MI GuoHua ZHANG FuSuo | 2013 | Science China(Life Sciences)2013，56，6： | 27 |
| 7 | Predicting value of serum soluble ST2 and interleukin-33 for risk stratification and prognosis in patients with acute myocardial infarction显示文摘 | ZHANG Kun ZHANG Xin-chao MI Yu-hong LIU Juan | 2013 | Chinese Medical Journal2013，，19： | 27 |
| 8 | Patterns and driving factors of WUE and NUE in natural forest ecosystems along the North-South Transect of Eastern China显示文摘从 2008 年 7 月,到 2008 年 8 月,从 22 种类的 72 件叶样品和在九天赋的 81 件土壤样品,森林生态系统对沿着东方中国(NSTEC ) 的纵贯的横断的南方镇定,从北方。把样品基于这些,我们学习了蔬菜水使用效率(WUE ) 和氮使用效率(NUE ) 的地理分发模式,并且分析了他们与环境因素的关系。蔬菜 WUE 和 NUE 分别地通过叶的 13C 的测量和占优势的种类的 C/N 被计算。结果出现了:(1 ) 蔬菜 WUE,从 2.13 ~ 28.67 mg C g1 H2O ,当蔬菜 NUE 显示出一个相反的趋势时,沿着 NSTEC 在代表性的森林生态系统从南方线性地增加了到北方,从北方增加到南方,从 12.92 ~ 29.60 g C g1 N 。(2 ) 蔬菜 WUE 和 NUE 被气候主导地驾驶并且显著地由土壤营养素因素影响。基于集中为 WUE 的 75.5% 变化正在回答的多重逐步的回归分析,吝啬的年度温度,土壤磷集中,和土壤氮(p < 0.001 ) 。当时,吝啬的年度降水和土壤磷集中能在蔬菜 NUE 解释 65.7% 变化(p < 0.001 ) 。而且,蔬菜 WUE 和 NUE 将被大气的氮免职严重也在氮影响浸透的生态系统。(3 ) 在沿着 NSTEC 的典型森林生态系统在蔬菜 WUE 和 NUE 之间有一种重要交易关系(p < 0.001 ) ,沿着 NSTEC 在自然森林生态系统在资源利用为植被显示平衡策略。这研究建议那个全球变化将影响森林生态系统的资源使用效率。然而,当减少时,植被能由增加缺乏资源的使用效率适应那些变化相对宽大的。但是极端影响例如重氮免职,将打破这交易机制并且把戏剧的骚乱给生态系统 biogeochemical 周期。 | SHENG Wenping REN Shujie YU Guirui FANG Huajun JIANG Chunming ZHANG Mi | 2011 | Journal of Geographical Sciences2011，21，4： | 19 |
| 9 | A Bayesian Stepwise Discriminant Model for Predicting Risk Factors of Preterm Premature Rupture of Membranes: A Case-control Study显示文摘 | Li-Xia Zhang Yang Sun Hai Zhao Na Zhu Xing-De Sun Xing Jin Ai-Min Zou Yang Mi Ji-Ru Xu | 2017 | Chinese Medical Journal2017，，20： | 18 |
| 10 | Nutrients concentration and changes in decade-scale in the central Bohai Sea显示文摘The nutrients contents and distributions are discussed briefly, based on the data obtained in 1998~1999. Besides explanation of the results,a 20 a time series data of nutrients and biological parameters for central Bohai Sea are reviewed. It is found that both concentration and relative content of nutrients have been changed dramatically. The increase of nitrogen and decrease of phosphate and silicate led to the dramatically increase of N/P ratio and the decrease of Si/N ratio. The situation of nitrogen limiting in central Bohai Sea is gradually changing to that of relative lack of phosphate and silicate. The decrease of the Huanghe River input to the Bohai Sea may be responsible for this change. These in turn may limit the growth of diatom and thus promote the development of pyrrophyta if other conditions (e.g. temperature and hydrodynamics) are suitable. We conclude that this may be the major inducement factor of pyrrophyta red tide in the Bohai Sea. | Yu Zhigang 1,Mi Tiezhu 1,Yao Qingzhen 1,Xie Baodong 1,Zhang Jing 11 .CollegeofChemistryandChemicalEngineering ,OceanUniversityofQingdao ,Qingdao 2 6 6 0 0 3 ,China | 2001 | Acta Oceanologica Sinica2001，20，1： | 18 |
| 11 | Discrimination of abiogenic and biogenic alkane gases显示文摘We have combined the analytical data of the carbon isotope distribution pattern, R/Ra and CH4/3He values of abiogenic and biogenic (referring to the thermogenic and bacterial or microbial) alkane gases in China with those of alkane gases from USA, Russia, Germany, Australia and other countries. Four discrimination criteria are derived from this comparative study: 1) Carbon isotopic composition is generally greater than -30‰ for abiogenic methane and less than -30‰ for biogenic methane; 2) Abiogenic alkane gases have a carbon isotopic reversal trend (δ 13C1> δ 13C2> δ 13C3> δ 13C4) with δ 13C1>-30‰ in general; 3) Gases with R/Ra >0.5 and δ 13C11 δ 13C2>0 are of abiogenic origin; 4) Gases (meth- ane) with CH4/3He≤106 are of abiogenic origin, whereas gases with CH4/3He≥1011 are of biogenic origin. | DAI JinXing ZOU CaiNeng ZHANG ShuiChang LI Jian NI YunYan HU GuoYi LUO Xia TAO ShiZhen ZHU GuangYou MI JingKui LI ZhiSheng HU AnPing YANG Chun ZHOU QingHua SHUAI YanHua ZHANG Ying MA ChengHua | 2008 | Science China Earth Sciences2008，51，12： | 17 |
| 12 | Synergistic antitumoral activity and induction of apoptosis by novel pan Bcl-2 proteins inhibitor apogossypolone with adriamycin in human hepatocellular carcinoma显示文摘瞄准:调查在里面 vitro 并且在 vivo 活动和 apogossypolone (ApoG2 ) 的相关机制独自或在有对人的 hepatocellular 癌(HCC ) 的 adriamycin (ADM ) 的联合。方法:在 vitro 的 ApoG2 的 IC 50 被 WST 试金测试,并且 synergistic 效果用 CalcuSyn 方法被分析。房间 apoptosis 用 4',6-diamidino-2-phenylindole 染色和流动 cytometric 分析被决定。西方的弄污被用来决定 apoptosis 相关的蛋白质的表示。在 vivo,活动在裸体老鼠在异种皮移植模特儿被评估,并且在肿瘤纸巾的 apoptosis 被终端 deoxynucleotidyl 决定标记的调停 transferase 的 digoxigenin-dUTP 刻痕结束(TUNEL ) 试金。结果:在 HCC 房间的 ApoG2 的 IC 50 是 17.28 30.63 μmol/L。当 ApoG2 与 ADM 被相结合时,增加的 cytotoxicity 和 apoptosis 独自与 ApoG2 与处理相比在 SMMC-7721 房间被观察。西方的弄污结果显示 ApoG2 在 SMMC-7721 房间导致了 apoptosis 由在调整 anti-apoptotic 蛋白质 Bcl-2, Mcl-1,和 Bcl-X L , 起来调整的 pro-apoptotic 蛋白质 Noxa,并且支持 caspases-9 和 -3 的活动。当没有引起损坏到正常纸巾, ApoG2 口头上地被管理时,异种皮移植 SMMC-7721 的肿瘤生长在裸体老鼠被禁止。在里面当在 100 或 200 mg/kg 剂量的 ApoG2 在 5.5 mg/kg 和 ADM 被使用时, vivo 学习也显示了增加的 anti-tumoral 效果,与相对肿瘤增长,率(T/C ) 分别地 0.456 和 0.323 珍视。与 ADM 独自一个或联合的 ApoG2 在 vivo 导致的 Apoptosis 被 TUNEL 试金在肿瘤纸巾证实。结论:ApoG2 是在调整 Noxa 上面导致 apoptosis 由的一个潜在的无毒的目标代理人,当禁止 anti-apoptotic 蛋白质并且在 HCC 支持化疗代理人 ADM 的效果时。 | Jin-xia MI Guang-feng WANG Heng-bang WANG Xiao-qing SUN Xin-yan NI Xiong-wen ZHANG Jia-ming TANG Da-jun YANG | 2008 | Acta Pharmacologica Sinica2008，29，12： | 16 |
| 13 | Atomic force microscopy imaging and mechanical properties measurement of red blood cells and aggressive cancer cells显示文摘Mechanical properties play an important role in regulating cellular activities and are critical for unlocking the mysteries of life. Atomic force microscopy (AFM) enables researchers to measure mechanical properties of single living cells under physiological conditions. Here, AFM was used to investigate the topography and mechanical properties of red blood cells (RBCs) and three types of aggressive cancer cells (Burkitt's lymphoma Raji, cutaneous lymphoma Hut, and chronic myeloid leukemia K562). The surface topography of the RBCs and the three cancer cells was mapped with a conventional AFM probe, while mechanical properties were investigated with a microsphere glued onto a tip-less cantilever. The diameters of RBCs are significantly smaller than those of the cancer cells, and mechanical measurements indicated that Young's modulus of RBCs is smaller than those of the cancer cells. Aggressive cancer cells have a lower Young's modulus than that of indolent cancer cells, which may improve our understanding of metastasis. | LI Mi LIU LianQing XI Ning WANG YueChao DONG ZaiLi XIAO XiuBin ZHANG WeiJing | 2012 | Science China(Life Sciences)2012，55，11： | 16 |
| 14 | Impact of disinfection on drinking water biofilm bacterial community显示文摘Disinfectants are commonly applied to control the growth of microorganisms in drinking water distribution systems. However, the effect of disinfection on drinking water microbial community remains poorly understood. The present study investigated the impacts of different disinfectants(chlorine and chloramine) and dosages on biofilm bacterial community in bench-scale pipe section reactors. Illumina MiS eq sequencing illustrated that disinfection strategy could affect both bacterial diversity and community structure of drinking water biofilm. Proteobacteria tended to predominate in chloraminated drinking water biofilms, while Firmicutes in chlorinated and unchlorinated biofilms. The major proteobacterial groups were influenced by both disinfectant type and dosage. In addition, chloramination had a more profound impact on bacterial community than chlorination. | Zilong Mi Yu Dai Shuguang Xie Chao Chen Xiaojian Zhang | 2015 | Journal of Environmental Sciences2015，27，11： | 16 |
| 15 | Change in cholesterol absorption and synthesis markers in patients with coronary heart disease after combination therapy with simvastatin plus ezetimibe显示文摘 | ZHANG Tao WU Wen-feng LIU Yang WANG Qi-hui WANG Lü-ya MI Shu-hua | 2013 | Chinese Medical Journal2013，，9： | 16 |
| 16 | The global significance of biodiversity science in China: an overview显示文摘Biodiversity science in China has seen rapid growth over recent decades,ranging from baseline biodiversity studies to understanding the processes behind evolution across dynamic regions such as the Qinghai-Tibetan Plateau.We review research,including species catalogues;biodiversity monitoring;the origins,distributions,maintenance and threats to biodiversity;biodiversity-related ecosystem function and services;and species and ecosystems'responses to global change.Next,we identify priority topics and offer suggestions and priorities for future biodiversity research in China.These priorities include(i)the ecology and biogeography of the Qinghai-Tibetan Plateau and surrounding mountains,and that of subtropical and tropical forests across China;(ii)marine and inland aquatic biodiversity;and(iii)effective conservation and management to identify and maintain synergies between biodiversity and socio-economic development to fulfil China's vision for becoming an ecological civilization.In addition,we propose three future strategies:(i)translate advanced biodiversity science into practice for biodiversity conservation;(ii)strengthen capacity building and application of advanced technologies,including high-throughput sequencing,genomics and remote sensing;and(iii)strengthen and expand international collaborations.Based on the recent rapid progress of biodiversity research,China is well positioned to become a global leader in biodiversity research in the near future. | Xiangcheng Mi Gang Feng Yibo Hu Jian Zhang Lei Chen Richard T.Corlett Alice C.Hughes Stuart Pimm Bernhard Schmid Suhua Shi Jens-Christian Svenning Keping Ma | 2021 | National Science Review2021，8，7： | 16 |
| 17 | Impact of obstructive sleep apnea on pulmonary hypertension in patients with chronic obstructive pulmonary disease显示文摘Background:Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) syndrome are highly prevalent respiratory conditions. Their coexistence is referred to as the overlap syndrome. They are both related to pulmonary hypertension (PH) development. This study investigated the effects of OSA on PH in patients with COPD and the associated factors. Methods: Consecutive patients with stable COPD were recruited for an observational cross-sectional study from September 2016 to May 2018 at Peking University Third Hospital. In total, 106 patients with COPD were enrolled and performed home portable monitoring and echocardiography. OSA was defined by an apnea hypopnea index (AHI)>10 events/h. Based on OSA absence or presence, patients were divided into the COPD with OSA and COPD without OSA groups. Factors affecting pulmonary artery pressure (PAP) and PH were identified using univariate analysis and logistic regression models. Results: In the 106 patients with COPD, the mean age was 69.52 years, 91.5% were men, and the mean forced expiratory volume in 1 s (FEV!) percentage of predicted was 56.15%. Fifty-six (52.8%) patients with COPD were diagnosed with OSA, and 24 (22.6%) patients with COPD were diagnosed as PH. Compared with COPD without OSA group, the median PAP in COPD with severe OSA group increased by 5 mmHg (36.00 [26.00-50.00] mmHg vs. 31.00 [24.00-34.00] mmHg, P = 0.036). COPD with percent of night-time spent with oxygen saturation below 90%(T90)> 10% group had higher PAP than COPD with T90 < 1 % group (36.00 [29.00-50.00)] mmHg vs. 29.00 [25.50-34.00] mmHg, F = 7.889, P = 0.007). Univariate analysis revealed age, FEVi% predicted, T90, and Charlson index had statistically significant effects on PH. Multiple regression analysis showed a significant and independent effect of both FEVj% predicted (odds ratio [OR]= 3.46;95% confidence interval [Cl]: 1.15-10.46;P = 0.028) and AHI (OR = 3.20;95% Cl: 1.09-19.35;P = 0.034) on PH. Conclusions: Patients with COPD with OSA are more susceptible to PH, which is associated with declining lung function and increased severity of OSA. Thus, nocturnal hypoxemia and OSA in elderly patients with COPD should be identified and treated. | Wan-Lu Sun Jian-Li Wang Guo-Hua Jia Wen-Jun Mi Yi-Xuan Liao Yong-Wei Huang Zheng Hu Li-Qiang Zhang Ya-Hong Chen | 2019 | Chinese Medical Journal2019，，11： | 15 |
| 18 | Root growth in response to nitrogen supply in Chinese maize hybrids released between 1973 and 2009显示文摘Root growth has a fundamental role in nitrogen (N) use efficiency.Nevertheless,little is known about how modern breeding progress has affected root growth and its responses to N supply.The root and shoot growth of a core set of 11 representative Chinese maize (Zea mays L.) hybrids released between 1973 and 2009 were investigated under high N (4 mmol L?1,HN) and low N (0.04 mmol L?1,LN) levels in a solution culture system.Compared with LN,HN treatment decreased root dry weight (RDW),the root:shoot ratio (R/S),and the relative growth rate for root dry weight (RGRroot),but increased the total root length (TRL) and the total lateral root length (LRL).The total axial root length (ARL) per plant was reduced under HN,mostly in hybrids released before the 1990s.The number of seminal roots (SRN) was largely unaffected by different N levels.More recently released hybrids showed higher relative growth rates in the shoot under both HN and LN.However,the roots only showed increased RGR under HN treatment.Correspondingly,there was a positive linear relationship with the year of hybrid release for TRL,LRL and ARL under HN treatment.Together,these results suggest that while shoot growth of maize has improved,its root growth has only improved under high N conditions over the last 36 years of selective breeding in China.Improving root growth under LN conditions may be necessary to increase the N use efficiency of maize. | WU QiuPing CHEN FanJun CHEN YanLing YUAN LiXing ZHANG FuSuo MI GuoHua | 2011 | Science China(Life Sciences)2011，54，7： | 15 |
| 19 | Resveratrol effectively attenuates α-naphthyl- isothiocyanate-induced acute cholestasis and liver injury through choleretic and anti-inflammatory mechanisms显示文摘 | Tao WANG Zhi-xing ZHOU Li-xin SUN Xia LI Zhi-meng XU Mi CHEN Guo-lin ZHAO Zhen-zhou JIANG Lu-yong ZHANG | 2014 | Acta Pharmacologica Sinica2014，35，12： | 14 |
| 20 | Distribution and source of microplastics in China's second largest reservoir-Danjiangkou Reservoir显示文摘Fresh water microplastic pollution is of pressing concern globally,but its distribution and sources in reservoirs are poorly documented.Danjiangkou Reservoir is the second largest reservoir in China and is divided into the Han Reservoir and Dan Reservoir.In this work,microplastic abundances and morphological characteristics of the reservoir were investigated.The microplastic abundance of 15 main tributaries of the reservoir was also measured.The vertical distribution(in water column and sediment),horizontal distribution(in Han Reservoir and Dan Reservoir)and source of microplastics were analyzed.Microplastics accumulated in the middle layer of the reservoir,and the size and color of the microplastic particles changed from the surface to the bottom,which implies that surveys of surface water are not enough to determine the microplastic contamination for deep water reservoirs.In the surface water,the microplastic abundance in the Han Reservoir was lower than that in the Dan Reservoir(p<0.05),but microplastic abundance did not differ significantly in the intermediate and bottom water.Tributaries were one of the main sources of microplastics for Han Reservoir but not for Dan Reservoir.Agricultural cultivation in the hydro-fluctuation belt might be an important source of microplastics in the Dan Reservoir,which should be given additional attention.The results of this study can provide valuable information for developing microplastic sampling strategies in deep water reservoirs.Further studies are recommended to investigate the process through which microplastics in the hydro-fluctuation belt enter the reservoir and the sinking behavior of microplastics in the reservoir. | Li Lin Xiong Pan Sheng Zhang Danwen Li Wenliang Zhai Zhen Wang Jingxiang Tao Changqing Mi Qingyun Li John C.Crittenden | 2021 | Journal of Environmental Sciences2021，33，4： | 13 |
您所在的机构暂未开通此部分的功能，请联系管理员