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您的检索式：作者名="Zhaomeng Cui"
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| 1 | Ethacrynic acid targets GSTM1 to ameliorate obesity by promoting browning of white adipocytes显示文摘Dear Editor,Obesity is caused by an imbalance between energy intake and expenditure,and has become a global epidemic with over 650 million adults affected.Adipose tissues in mammals are composed of white adipose tissue(WAT)and classical brown adipose tissue(BAT),and their balance is highly related to the occurrence of obesity.The browning of white adipocytes results in“beige”or“brite”adipocytes,which appear functionally similar to classical brown adipocytes,and can be detected in WAT deposits of animals that have been exposed to cold or other inducers(Fu et al.,2015). | Zhaomeng Cui Yang Liu Wei Wan Yuyan Xu Yehui Hu Meng Ding Xin Dou Ruina Wang Hailing Li Yongmei Meng Wei Li Wei Jiang Zengxia Li Yiming Li Minjia Tan Dengke KMa Yu Ding Jun OLiu Cheng Luo Biao Yu Qiqun Tang Yongjun Dang | 2021 | Protein & Cell2021，12，6： | 1 |
| 2 | Comparison on Clinical Characteristics of Multifocal Choroiditis and Punctate Inner Choroidopathy显示文摘Purpose:To compare the differences in the clinical characteristics of multifocal choroiditis(MFC) and punctate inner choriodopathy(PIC).Methods:A cross-sectional study,consisting of 22 cases(37 eyes) with MFC and 11 cases(18 eyes) with PIC,was carried out.Multiple indexes were measured and analysed to compare the differences in clinical characteristics of the subjects between two groups,including BCVA,avergae age,sex composition,presence of intraocular inflammation,choroidal neovascularization(CNV),and intraocular inflammation complications,such as cataract,cystoid macular edema(CME) and epiretinal membrane(ERM).Results:The avergae age of the MFC and PIC patients were(48.1±13.9) years and(32.1±10.2) years with a significant difference(P=0.043).CNV occurred more frequently in patients with PIC(PIC,55.6%;MFC,21.6%;P=0.016) compared with those with MFC.MFC patients had a higher frequency of intraocular inflammation complications,such as,cataract(27.0%),CME(35.1%),ERM(5.4%).PIC patients presented none of these complications.MFC subjects presented with more visual impairments than PIC patients.Totally 51.4% of MFC patients had visual impairments and 22.2% of PIC patients had BCVA < 0.3(P=0.047).Conclusion:Both MFC and PIC are categorized into the umbrella term of 'white spot syndromes'.Although sharing similar ocular expressions,they present with different clinical characteristics.Patients with PIC had a higher frequency of CNV but a lower frequency of structural complications caused by intraocular inflammation and lower frequency of visual impairments compared with MFC counterparts. | Zhaomeng Shen linyi Zhang Zhiguo Li Xian Zhang Hongbo Cui | 2011 | Eye Science2011，26，3： | 0 |
| 3 | 靶向eIF4AI的N-末端抑制其催化循环显示文摘文章简介蛋白翻译是中心法则的最后一环,是控制细胞内蛋白质稳态的关键生命过程。蛋白翻译起始是整个翻译过程中最关键的限速步骤,翻译过程的失调与神经发育类疾病以及恶性肿瘤等多种疾病密切相关。真核蛋白翻译起始因子eIF4A是最早被发现的DEAD盒(DEAD-box)RNA解旋酶超家族成员。 | 蒋晨晓 汤叶根 丁露露 Renke Tan Xiaojing Li Junyan Lu Jing Jiang Zhaomeng Cui Zhewei Tang Wei Li Zhangjun Cao Tilman Schneider-Poetsch Wei Jiang Cheng Luo 丁滪 刘建伟 党永军 | 2020 | 科学新闻2020，，2： | 0 |
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