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| 1 | A highly porous animal bone-derived char with a superiority of promoting nZVI for Cr(Ⅵ)sequestration in agricultural soils显示文摘Paddy soil and irrigation water are commonly contaminated with hexavalent chromium[Cr(Ⅵ)]near urban industrial areas,thereby threatening the safety of agricultural products and human health.In this study,we develop a porous and high specific area bone char(BC)to support nanoscale zero-valent iron(n ZVI)and apply it to remediate Cr(Ⅵ)pollution in water and paddy soil under anaerobic conditions.The batch experiments reveal that BC/n ZVI exhibits a higher removal capacity of 516.7 mg/(g·n ZVI)for Cr(Ⅵ)than n ZVI when normalized to the actual n ZVI content,which is 2.8 times that of n ZVI;moreover,the highest n ZVI utilization is the n ZVI loading of 15%(BC/n ZVI15).The Cr(Ⅵ)removal efficiency of BC/n ZVI15 decreases with increasing p H(4–10).Coexisting ions(phosphate and carbonate)and humic acid can inhibit the removal of Cr(Ⅵ)with BC/n ZVI15.Additionally,BC exhibits a strong advantage in promoting Cr(Ⅵ)removal by n ZVI compared to the widely used biochar and activated carbon.Our results demonstrate that reduction and coprecipitation are the dominant Cr(Ⅵ)removal mechanisms.Furthermore,BC/n ZVI15 shows a significantly higher reduction and removal efficiency as well as a strong anti-interference ability for Cr(Ⅵ)in paddy soil,as compared to n ZVI.These findings provide a new effective material for remediating Cr(Ⅵ)pollution from water and soil. | Kai Liu Fangbai Li Qingwen Tian Chengrong Nie Yibing Ma Zhenlong Zhu Liping Fang Yuanying Huang Siwen Liu | 2021 | Journal of Environmental Sciences2021，33，6： | 7 |
| 2 | Human mobility data in the COVID-19 pandemic:characteristics,applications,and challenges显示文摘The COVID-19 pandemic poses unprecedented challenges around the world.Many studies have applied mobility data to explore spatiotemporal trends over time,investigate associations with other variables,and predict or simulate the spread of COVID-19.Our objective was to provide a comprehensive overview of human mobility open data to guide researchers and policymakers in conducting data-driven evaluations and decision-making for the COVID-19 pandemic and other infectious disease outbreaks.We summarized the mobility data usage in COVID-19 studies by reviewing recent publications on COVID-19 and human mobility from a data-oriented perspective.We identified three major sources of mobility data:public transit systems,mobile operators,and mobile phone applications.Four approaches have been commonly used to estimate human mobility:public transit-based flow,social activity patterns,index-based mobility data,and social media-derived mobility data.We compared mobility datasets’characteristics by assessing data privacy,quality,space–time coverage,high-performance data storage and processing,and accessibility.We also present challenges and future directions of using mobility data.This review makes a pivotal contribution to understanding the use of and access to human mobility data in the COVID-19 pandemic and future disease outbreaks. | Tao Hu Siqin Wang Bing She Mengxi Zhang Xiao Huang Yunhe Cui Jacob Khuri Yaxin Hu Xiaokang Fu Xiaoyue Wang Peixiao Wang Xinyan Zhu Shuming Bao Wendy Guan Zhenlong Li | 2021 | International Journal of Digital Earth2021，14，9： | 1 |
| 3 | Research and development of nontraditional machining in china 显示文摘 | Zhao Wansheng Zhu Di Wang Zhenlong | 2000 | International Journal of Electrical Machining2000，，5： | 1 |
| 4 | Complex spatial patterns delay the discovery and location of food by rodents显示文摘Spatial patterns in heterogeneity are generally deemed a central causal factor influencing the physiology and behavior of animals in ecological systems.However,knowledge remains limited about how such patterns influence food discovery by animals.We inferred that spatial heterogeneity plays a key role in animal food discovery and location.To prove this inference,we tested food locating parameters by 2 rodent species,Apodemus agrarius and Lasiopodomys brandtii,in different heterogeneous environments.Our results showed that spatial heterogeneity significantly influenced the food locating time of rodents,with food locating time increasing with increasing spatial heterogeneity.Furthermore,spatial heterogeneity significantly influenced invalid excavations(digging in the wrong place).Finally,spatial heterogeneity significantly influenced the frequency that heterogeneous objects were explored.Supporting our inference,our results indicate that spatial heterogeneity significantly influences the foraging behavior of animals.Consequently,increased spatial heterogeneity will impair the food locating success of rodents.We believe that this work will broaden our understanding of plant–animal interactions. | Shiqiang ZHANG Meilin ZHU Huixia ZHANG Nannan YAO Yingying WANG Yifeng ZHANG Zhenlong WANG | 2020 | Integrative Zoology2020，15，4： | 0 |
| 5 | Experimental and theoretical analysis of a hybrid vibration energy harvester with integrated piezoelectric and electromagnetic interaction显示文摘Harvesting vibration energy has attracted the attention of researchers in recent decades as a promising approach for powering wireless sensor networks.The hybridization of piezoelectricity and electromagnetism has proven helpful in the improvement of vibration energy harvesting.In this study,we explore the integration of piezoelectric and electromagnetic parts in one vibration energy harvesting device.Lumped-parameter models of the system are derived considering the different connection topologies of the piezoelectric and electromagnetic parts.Numerical predictions from these models are compared with experimental results to throw light on the nonlinearities in the system.Modifications of the system are also explored to provide insights into opportunities to improve its performance and that of future vibration energy harvesters. | Shifan HUANG Weihao LUO Zongming ZHU Zhenlong XU Ban WANG Maoying ZHOU Huawei QIN | 2023 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2023，24，11： | 0 |
| 6 | REGγ drives Lgr5^(+) stem cells to potentiate radiation induced intestinal regeneration显示文摘Leucine-rich repeat containing G protein-coupled receptor 5(Lgr5), a marker of intestinal stem cells(ISCs), is considered to play key roles in tissue homoeostasis and regeneration after acute radiation injury. However, the activation of Lgr5 by integrated signaling pathways upon radiation remains poorly understood. Here, we show that irradiation of mice with whole-body depletion or conditional ablation of REGγ in Lgr5^(+) stem cell impairs proliferation of intestinal crypts, delaying regeneration of intestine epithelial cells. Mechanistically, REGγ enhances transcriptional activation of Lgr5 via the potentiation of both Wnt and Hippo signal pathways. TEAD4 alone or cooperates with TCF4, a transcription factor mediating Wnt signaling, to enhance the expression of Lgr5. Silencing TEAD4 drastically attenuated β-catenin/TCF4 dependent expression of Lgr5. Together, our study reveals how REGγ controls Lgr5 expression and expansion of Lgr5+stem cells in the regeneration of intestinal epithelial cells.Thus, REGγ proteasome appears to be a potential therapeutic target for radiation-induced gastrointestinal disorders. | Xiangzhan Zhu Minglei Yang Zaijun Lin Solomon Kibreab Mael Ya Li Lili Zhang Yaqi Kong Yaodong Zhang Yuping Ren Jianhui Li Zimeng Wang Ying Zhang Bo yang Tingmei Huang Fangxia Guan Zhenlong Li Robb E Moses Lei Li Bing Wang Xiaotao Li Bianhong Zhang | 2022 | Science China(Life Sciences)2022，65，8： | 0 |
| 7 | Amplified visualization and function exploration of exosomal protein-specific glycosylation using hybridization chain reaction from non-functional epitope显示文摘Exosomal glycoproteins play significant roles in many physiological and pathological procedures. However, the current methods for studying exosomal glycoproteins have low sensitivity or can affect exosomal biological function. Herein, we developed a proximity dual-tagging strategy using an induced hybridization chain reaction(HCR) from the target’s non-functional epitope for amplified visualization and functional exploration of exosomal protein-specific glycosylation. This strategy leverages dualtagging based on the aptamer with little influence on target function and metabolic glycan labelling, and the rigid product and high sensitivity of HCR. The method improves the signal of visualizing exosomal PD-L1(exo PD-L1) by 7.7-fold compared with the signal without HCR amplification without affecting the natural exo PD-L1/PD-1 interaction. As a result, we verified that the interaction between exo PD-L1 and PD-1 positive cells is positively correlated to the glycosylation level of exo PD-L1. Overall,we have developed a sensitive method with little functional influence to visualize exosomal protein-specific glycosylation in situ,offering a powerful tool for studying the biological implications of exosomal glycoproteins. | Siyin Kang Lin Zhu Wencheng Wang Yinzhu Lu Zhenlong You Chi Zhang Yuanfeng Xu Chaoyong Yang Yanling Song | 2022 | Science China Chemistry2022，65，6： | 0 |
| 8 | Stratum Griseum Periventriculare-mediated Fear Emotion Regulates Motor Behavior in Pigeons显示文摘A pigeon robot is an ideal experimental animal for research in flying animal robots.The majority of current research publications have entailed electrical stimulation of the motor nuclei to regulate movement forcibly,and although a“virtual fear”behavior model has been proposed,the structure,location,and function of the nuclei that generate fear emotions remain obscure.Previous studies have shown that the Stratum Griseum Periventriculare(SGP)of pigeons is homologous to the mammalian periaqueductal gray(PAG),which plays an essential role in mammalian fear.To reveal the role of fear mediated by the SGP in behavioral regulation,we evaluated the structure and location of the SGP by histologic identification combined with magnetic resonance imaging,and analyzed the behavior of the SGP by electrical stimulation.Finally,the function of the SGP was verified with escape testing and homing experiments in an open field.Our results showed that the SGP is located in the pigeon midbrain and divided into two subregions,the dorsal part of the stratum griseum periventriculare(SGPd)and the ventral part of the stratum griseum periventriculare(SGPv)(the ranges were AP1.5–4.75 mm,ML1.75–6.75 mm,and DV2.2–7.1 mm),and that wired and wireless electrical stimulation freezing was the dominant behavior.In the escape test,SGP electrical stimulation caused the pigeons to flee to a safe place,while in the open-field homing test,electrical stimulation of the SGP induced evasive behavior in pigeons away from their original homing route.These results confirm that the SGP plays a crucial role in fear,and that electrical stimulation of this nucleus induces corresponding fear behaviors. | Wenbo Xu Long Yang Zishi Wang Lifang Yang Han Cheng Shixin Zhu Zhigang Shang Zhenlong Wang | 2023 | Journal of Bionic Engineering2023，20，5： | 0 |
| 9 | Stability Control of Gob-Side Entry Retaining in Fully Mechanized Caving Face Based on a Compatible Deformation Model显示文摘The stability control of gob-side entry retaining in fully mechanized caving face is a typical challenge in many coal mines in China.The rotation and subsidence of the lateral cantilever play a critical role in a coal mine,possibly leading to instability in a coal seam wall or a gob-side wall due to its excessive rotation subsidence.Hence,the presplitting blasting measures in the roof was implemented to cut down the lower main roof and convert it to caved immediate roof strata,which can significantly reduce the rotation space for the lateral cantilever and effectively control its rotation.Firstly,the compatible deformation model was established to investigate the quantitative relationship between the deformation of the coal seam wall and the gob-side wall and the subsidence of the lateral cantilever.Then,the instability judgments for the coal seam wall and gob-side wall were revealed,and the determination method for the optimal roof cutting height were obtained.Furthermore,The Universal Distinct Element Code numerical simulation was adopted to investigate the effect of roof-cutting height on the stability of the retained entry.The numerical simulation results indicated that the deformation of the roadway could be effectively controlled when the roofcutting height reached to 18 m,which verified the theoretical deduction well.Finally,a field application was performed at the No.3307 haulage gateway in the Tangan coal mine,Ltd.,Shanxi Province,China.The field monitoring results showed that the blasting roof cutting method could effectively control the large deformation of surrounding rocks,which provided helpful references for coal mine safety production under similar conditions. | Xinshuai Shi Hongwen Jing Jianguo Ning Zhenlong Zhao Junfu Zhu | 2020 | Computer Modeling in Engineering & Sciences2020，，7： | 0 |
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