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| 1 | Efficacy of second-course intra-arterial chemotherapy in children for advanced retinoblastoma recurrence after intra-arterial chemotherapy显示文摘Purpose: The present study determined the efficacy and toxicity of second-course intra-arterial chemotherapy(IAC) in advanced retinoblastoma(RB) recurrence in children following failed initial IAC. Materials and Methods: A total of 24 child patients with unilateral or bilateral intra-ocular advanced RB(IIRC Group D and Group E) undergoing second-course IAC treatment after initial intra-arterial chemotherapy between September 2011 and November 2016 were enrolled. Global salvage, ocular adverse events, and systemic adverse events were assessed. Results: Following second-course IAC, 15(62.5%) showed complete control at 34 months follow-up, while 8 cases(33.3%) failed the treatment and 1 patient with metastatic disease(4.2%) eventually died of brain metastasis after refusing treatment. Ocular adverse events included eyelid edema(n=12), ptosis(n=5), forehead erythema(n-5), enophthalmos(n=3), and cataract(n=2). None of the patients had systemic adverse events, such as stroke or sepsis. Also, no secondary neoplasms and technical complications were observed. Conclusion: Second-course IAC is a potential alternative to enucleation in children with advanced RB, who fail an initial course of IAC. However, patients with advanced RB should be managed at experienced centers in order to consider all the alternatives before enucleation. | Hua Jiang Gang Shen Wenchan Xu Chuanqiang Niu Zhenyin Liu Jiejun Xia Jing Zhang | 2018 | Journal of Interventional Medicine2018，1，2： | 2 |
| 2 | Temporal changes in matrix metalloproteinase expression and inflammatory response associ- ated with cardiac rupture after myocardial infraction in mice 显示文摘 | Tao Zhenyin Cavasin M A Yang Fang | 2004 | Life Sci2004，74，12： | 1 |
| 3 | Numerical Simulationof Vortex Cavitation in a Three-Dimensional SubmergedTransitional Jet显示文摘 | TAO Xing LI Zhenyin Steven H F | 2005 | Journal of Fluids Engineering2005，127，： | 1 |
| 4 | Temporal changes in matrix metalloproteinase expression and inflammatory response associated with cardiac rupture after myocardial infarction in mice 显示文摘 | TAO Zhenyin CAVASIN M A YANG Fang | 2004 | Life Sci2004，74，12： | 1 |
| 5 | Combination of radiofrequency ablation with transarterial chemoembolization for hepatocellular carcinoma: an up-to-date meta-analysis显示文摘 | Zhenyin Liu Fei Gao Guang Yang Sristi Singh Mingjian Lu Tao Zhang Zhihui Zhong Fujun Zhang Rijie Tang | 2014 | Tumor Biology2014，，8： | 1 |
| 6 | Temporal changes in matrix metalloproteninase expression and inflammatory response associated with cardiac rupture after myocardial infarction in mice 显示文摘 | Tao Zhenyin Maria A Yang Fang | 2004 | Life Science2004，74，12： | 1 |
| 7 | Degradation of SARS-CoV-2 receptor ACE2 by the E3 ubiquitin ligase Skp2 in lung epithelial cells显示文摘An unexpected observation among the COVID-19 pandemic is that smokers constituted only 1.4%–18.5%of hospitalized adults,calling for an urgent investigation to determine the role of smoking in SARS-CoV-2 infection.Here,we show that cigarette smoke extract(CSE)and carcinogen benzo(a)pyrene(BaP)increase ACE2 mRNA but trigger ACE2 protein catabolism.BaP induces an aryl hydrocarbon receptor(AhR)-dependent upregulation of the ubiquitin E3 ligase Skp2 for ACE2 ubiquitination.ACE2 in lung tissues of non-smokers is higher than in smokers,consistent with the findings that tobacco carcinogens downregulate ACE2 in mice.Tobacco carcinogens inhibit SARS-CoV-2 spike protein pseudovirions infection of the cells.Given that tobacco smoke accounts for 8 million deaths including 2.1 million cancer deaths annually and Skp2 is an oncoprotein,tobacco use should not be recommended and cessation plan should be prepared for smokers in COVID-19 pandemic. | Guizhen Wang Qun Zhao Hui Zhang Fan Liang Chen Zhang Jun Wang Zhenyin Chen Ran Wu Hong Yu Beibei Sun Hua Guo Ruie Feng Kaifeng Xu Guangbiao Zhou | 2021 | Frontiers of Medicine2021，15，2： | 1 |
| 8 | CT-guided implantation of radioactive 125 I seed in advanced non-small-cell lung cancer after failure of first-line chemotherapy显示文摘 | Tao Zhang Mingjian Lu Sheng Peng Weidong Zhang Guang Yang Zhenyin Liu Sristi Singh Yadi Yang Fujun Zhang Fei Gao | 2014 | Journal of Cancer Research and Clinical Oncology2014，，8： | 1 |
| 9 | Economic Analysis and Research of New Energy Vehicle Promotion Model显示文摘New energy vehicles represent the inevitable trend of future development.Compared to traditional fuel vehicles,they are more energy-saving and environmentally friendly,effectively reducing air pollution and mitigating excessive exploitation of oil resources,a stance strongly supported by governments.However,new energy vehicles possess certain drawbacks in terms of price and usability compared to traditional counterparts.Therefore,external support is imperative for their development.This paper delineates four main sections:the background of new energy vehicle promotion and application,a comparative analysis of domestic and foreign promotion models,specific promotion suggestions,and future development prospects.By leveraging insights from economic analysis,the optimal promotion model for new energy vehicles is elucidated. | Zihang Wang Xudong Wang Zhenyin Zhang Shaolong Wang Chenyang Xu | 2024 | Proceedings of Business and Economic Studies2024，7，1： | 0 |
| 10 | Preparation of safe water-lipid mixed electrolytes for application in ion capacitor显示文摘Aqueous electrolytes are safe,economic,and environmentally friendly.However,they have a narrow potential window.On the other hand,organic electrolytes exhibit good thermodynamic stability but are inflammable and moisture sensitive.In this study,we prepared water-PEG-lipid ternary electrolytes(TEs).To combine the advantages of water,polyethylene glycol(PEG)and propylene carbonate(PC).The nonflammable mixed electrolytes exhibited a wide potential window of about 2.8 V due to the beneficial effects of PEG and PC.Using these TEs,a lithium manganate-active carbon ion capacitor could be operated at 2.4 V with an energy density of 32 Wh/kg,based on the total active electrode material(current density of 3.3 m A/cm^(2)).This value was significantly higher than that achieved using an aqueous electrolyte,thereby rationalizing the higher energy density. | Miaofeng Huang Aihua Tang Zhenyin Wang Jingkun Shi Xiaoping Jiang Chubin Wan Xin Ju | 2021 | Chinese Chemical Letters2021，32，6： | 0 |
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