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| 1 | Individualized Design of the Ventilator Mask based on the Residual Concentration of CO2显示文摘OSAHS(Obstructive Sleep Apnea Hypopnea Syndrome)is a respiratory disease mainly characterized by limited and repeated pauses of breathing in sleep.Currently,the optimal treatment is to apply CPAP(Continuous Positive Airway Pressure)ventilation on the upper airway of the patient through a household respiratory machine.However,if the ventilator mask is designed improperly,it might cause the residue and repeated inhalation of CO2,which will exert an adverse impact on the therapeutic effect.Present research numerically analyzed the CO2 transportation inside a commercial ventilator mask(Mirage SoftGel,ResMed,Australia)based on the reconstructed 3D numerical model of a volunteer's face and performed the improved design of the ventilator mask in terms of the CO2 residual concentration below the nostrils.The fluid dynamic analyses showed that at the end time of expiratory,the CO2 residual concentration below the nostrils is close to 4%.To improve the therapeutic effect,we changed the position of the exhaust holes and found that by moving the exhaust holes to the bottom of the ventilator mask,the CO2 residual concentration below the nostrils would be reduced to no more than 1%.This study established a near physiological computational model and provided a new method for the individualized design of the commercial ventilator mask. | Zhiguo Zhang Zhenxiao Li Yifei Zhang Zhenze Wang Minzhou Luo | 2018 | Computer Modeling in Engineering & Sciences2018，，11： | 3 |
| 2 | Enhanced learning and memory in GAT1 heterozygous mice显示文摘-Aminobutyric 酸(伽马氨基丁酸) 是在中央神经系统的主要禁止的 neurotransmitter。伽马氨基丁酸传播的结束通过膜蛋白质的一个家庭的行动,叫的伽马氨基丁酸 transporters (GAT14 ) 。伽马氨基丁酸系统涉及存储器的调整,这很好被建立。我们的以前的学习显示出老鼠展出了损害马头鱼尾的怪兽依赖者学习和记忆的那同型结合的 GAT1/ 。在鼠标上评估内长的减少的伽马氨基丁酸举起的影响认知行为,学习和异质接合的 GAT1+/ 鼠标的存储器的能力被被动回避范例和莫利斯舞水迷宫检测。洞板范例也被用来在如此的老鼠在焦虑相关的行为或探索行为测量变化。作为 synaptic 粘性的一种形式,长期的 potentiation 在老鼠被记录海马趾的 CA1 区域。我们发现了显示的老鼠增加了的那 GAT1+/ 学习并且记忆,减少的像焦虑的行为,和与野类型、同型结合的 GAT1/ 老鼠相比的最高的 synaptic 粘性。我们的结果建议在 GAT1 活动的中等减小引起在鼠标学习和记忆的改进。 | Jun Shi Youqing Cai Guoxiang Liu Neng Gong Zhenze Liu Tianle Xu Zhugang Wang Jian Fei | 2012 | Acta Biochimica et Biophysica Sinica2012，44，4： | 3 |
| 3 | Identification and characterization of BoPUB3: a novel interaction protein with S-locus receptor kinase in Brassica oleracea L.显示文摘Armadillo repeat containing 1 (ARC1) is phosphorylated by S-locus receptor kinase (SRK) and functions as a positive regulator in self-incompatibility response of Brassica. However, ARC1 only causes partial breakdown of the self-incompatibility response, and other SRK downstream factors may also participate in the self-incompatibility signaling pathway. In the present study, to search for SRK downstream targets, a plant U-box protein 3 (BoPUB3) was identified from the stigma of Brassica oleracea L. BoPUB3 was highly expressed in the stigma, and its expression was increased with the stigma development and reached to the highest level in the mature-stage stigma. BoPUB3, a 76.8-kDa protein with 697 amino acids, is a member of the PUB-ARM family and contains three domain characteristics of BoARC1, including a U-box N-terminal domain, a U-box motif, and a C-terminal arm repeat domain. The phylogenic tree showed that BoPUB3 was close to BoARC1. The synteny analysis revealed that B. oleracea chromosomal region containing BoPUB3 had high synteny with the Arabidopsis thaliana chromosomal region containing AtPUB3 (At3G54790). In addition, the subcellular localization analysis showed that BoPUB3 primarily localized in the plasma membrane and also in the cytoplasm. The combination of the yeast two-hybrid and in vitro binding assay showed that both BoPUB3 and BoARC1 could interact with SRK kinase domain, and SRK showed much higher level of β-galactosidase activity in its interaction with BoPUB3 than with BoARC1. These results implied that BoPUB3 is a novel interactor with SRK, which lays a basis for further research on whether PUB3 participates in the self-incompatibility signaling pathway. | Songmei Shi Qiguo Gao Tonghong Zuo Zhenze Lei Quanming Pu Yukui Wang Guixi Liu Xinhua He Xuesong Ren Liquan Zhu | 2019 | Acta Biochimica et Biophysica Sinica2019，51，7： | 2 |
| 4 | Linking atomic structural defects to mesoscale properties in crystalline solids using graph neural networks显示文摘Structural defects are abundant in solids,and vital to the macroscopic materials properties.However,a defect-property linkage typically requires significant efforts from experiments or simulations,and often contains limited information due to the breadth of nanoscopic design space.Here we report a graph neural network(GNN)-based approach to achieve direct translation between mesoscale crystalline structures and atom-level properties,emphasizing the effects of structural defects.Our end-to-end method offers great performance and generality in predicting both atomic stress and potential energy of multiple systems with different defects.Furthermore,the approach also precisely captures derivative properties which strictly observe physical laws and reproduces evolution of properties with varying boundary conditions.By incorporating a genetic algorithm,we then design de novo atomic structures with optimum global properties and target local patterns.The method would significantly enhance the efficiency of evaluating atomic behaviors given structural imperfections and accelerates the design process at the meso-level. | Zhenze Yang Markus J.Buehler | 2022 | npj Computational Materials2022，，1： | 2 |
| 5 | Cd( Ⅱ ) adsorption on various adsorbents obtained from charred biomaterials 显示文摘 | LI Zhenze KATSUMI T 1MAIZUMI S | 2010 | Journal of Hazardous Materials2010，183，123： | 1 |
| 6 | Cd( E ) adsorption onvarious adsorbents obtained from charred biomaterials 显示文摘 | LI Zhenze KATSUMI T’IMAIZUMI S cf o/ | 2010 | J HazardMater2010，183，123： | 1 |
| 7 | Impulsive control of passive compass-like biped robot based on anti-phase synchronization显示文摘 | Li Yong Du Qiaoling Liu Zhenze | 2011 | J of Jilin University: Engineering and Technology Edition2011，41，2： | 1 |
| 8 | Children with respiratory tract of notifia- ble infectious diseases hospital infection conU:ol measures显示文摘 | Li Yue Cui Zhenze Cui Ni | 2011 | Chinese hospital infection Journal2011，21，6： | 1 |
| 9 | Hydro-mechanical behavior of an argillaceous limestone considered as a potential host formation for radioactive waste disposal显示文摘The Canadian Nuclear Safety Commission(CNSC), Canada's nuclear regulator, conducts regulatory research in order to develop independent knowledge on safety aspects related to the deep geological disposal of radioactive wastes. In Canada, the Cobourg limestone of the Michigan Basin is currently considered as a potential host formation for geological disposal. The understanding of the hydromechanical behavior of such a host rock is one of the essential requirements for the assessment of its performance as a barrier against radionuclide migration. The excavation of galleries and shafts of a deep geological repository(DGR) can induce damage to the surrounding rock. The excavation damaged zone(EDZ) has higher permeability and reduced strength compared to the undisturbed rock and those factors must be considered in the design and safety assessment of the DGR. The extent and characteristics of the EDZ depend on the size of the opening, the rock type and its properties, and the in situ stresses, among other factors. In addition, the extent and characteristics of the EDZ can change with time due to rock strength degradation, evolution of fractures within the EDZ, and the redistribution of pore pressure around the excavation. In this research project initiated by the CNSC, the authors conducted experimental and theoretical research in order to assess the hydro-mechanical behavior of the Cobourg limestone under undamaged and damaged conditions, both in the short and long terms. The short-term behavior was investigated by a program of triaxial tests with the measurement of permeability evolution on specimens of Cobourg limestone. The authors formulate a coupled hydro-mechanical model to simulate the stress-strain response and evolution of the permeability during those triaxial tests. Using creep and relaxation data from a similar limestone, the model was extended to include its long-term strength degradation. The model successfully simulated both the short-and long-term hydro-mechanical behavior of the limestone during those tests. This provides confidence that the main physical processes have been adequately understood and formulated. | T.S.Nguyen Zhenze Li Grant Su M.H.B.Nasseri R.P.Young | 2018 | Journal of Rock Mechanics and Geotechnical Engineering2018，10，6： | 1 |
| 10 | ANALYTICAL SOLUTIONS FOR THE LAYERED GEO-MATERIALS SUBJECTED TO AN ARBITRARY POINT LOAD IN THE CARTESIAN COORDINATE显示文摘This paper presents analytical solutions for the stress and displacement field in elastic layered geo-materials induced by an arbitrary point load in the Cartesian coordinate system.The point load solutions can be obtained by referring to the integral transform and the transfer matrix technique.However,former solutions usually exist in the cylindrical coordinate system subjected to axisymmetric loading.Based on the proposed solutions in the Cartesian coordinate,it is very easy to solve asymmetric problems and consider the condition with internal loads in multi-layered geo-materials.Moreover,point load solutions can be used to construct solutions for analytical examination of elastic problems and incorporated into numerical schemes such as boundary element methods.The results discussed in this paper indicate that there is no problem in the evaluation of the point load solutions with high accuracy and efficiency,and that the material non-homogeneity has a significant effect on the elastic field due to adjacent loading. | Zhiguo Zhang Zhenze Li | 2011 | Acta Mechanica Solida Sinica2011，24，3： | 1 |
| 11 | Low-densitylipoprotein from apolipoprotein E-deficient mice induces macrophage lipid accumulation in a CD36 and scavenger receptor class A-dependent manner 显示文摘 | Zhao Zhenze de Beer MC Cai L | 2005 | Atheroscler Thromb Vasc Biol2005，25，： | 1 |
| 12 | Oxygen vacancy O-terminated surface:The most exposed surface of hexagonal WO3(001)surface显示文摘It is known that exposed surface determines material’s performance.WO3 is widely used in gas sensing and its working surface is proposed to control its sensitivity.However,the working surface,or most exposed surface with detailed surface structure remain unclear.In this paper,DFT calculation confirmed that oxygen vacancy O-terminated surface is the most exposed hexagonal WO3(001)surface,judging from competitive adsorption of CO and O2,working surface determination for CO sensing and comparison of oxygen vacancy formation ene rgies on different h-WO3(001)surfaces.It is found that DFT can be a useful alternate for exposed surface determination.Our results provide new perspectives and performance explanations for material research. | Feng Hui Tian Zhenze Liu Jin Tian Yunfan Zhang | 2020 | Chinese Chemical Letters2020，31，8： | 1 |
| 13 | Adsorption behavior and mechanism of Cd(II) on loess soil from China显示文摘 | Yan Wang Xiaowu Tang Yunmin Chen Liangtong Zhan Zhenze Li Qiang Tang | 2009 | Journal of Hazardous Materials2009，，1： | 1 |
| 14 | Molecular characterization of the celiac disease epitope domains in α-gliadin genes in Aegilops tauschii and hexaploid wheats (Triticum aestivum L.)显示文摘 | Zhenze Xie Congyan Wang Ke Wang Shunli Wang Xiaohui Li Zhao Zhang Wujun Ma Yueming Yan | 2010 | Theoretical and Applied Genetics2010，，7： | 1 |
| 15 | A point mutation in the MET oncogene abrogates metastasis without affecting transformton显示文摘 | Giordano S Bardell A ZhenZ etal | 1997 | Proc Natl Acad Sci USA1997，94，13： | 1 |
| 16 | Cd(II) adsorption on various adsorbents obtained from charred biomaterials显示文摘 | Zhenze Li Takeshi Katsumi Shigeyoshi Imaizumi Xiaowu Tang Toru Inui | 2010 | Journal of Hazardous Materials2010，，1： | 1 |
| 17 | Adsorption behavior of Zn(Ⅱ) on calcinated Chinese loess显示文摘 | TANG Xiaowu LI Zhenze CHEN Yunmin | 2009 | Journal of Hazardous Materials2009，161，23： | 1 |
| 18 | Spatial light modulation for femtosecond laser manufacturing:Current developments and challenges显示文摘Since the invention of lasers,spatial-light-modulated laser processing has become a powerful tool for various applications.It enables multidimensional and dynamic modulation of the laser beam,which significantly improves the processing efficiency,accuracy,and flexibility,and presents wider prospects over traditional mechanical technologies for machining three-dimensional,hard,brittle,or transparent materials.In this review,we introduce:(1)The role of spatial light modulation technology in the development of femtosecond laser manufacturing;(2)the structured light generated by spatial light modulation and its generation methods;and(3)representative applications of spatial-light-modulated femtosecond laser manufacturing,including aberration correction,parallel processing,focal field engineering,and polarization control.Finally,we summarize the present challenges in the field and possible future research. | ZANG Xue LIU ZiTing XU YiShi WANG Yi WANG Qing LI ZhenZe WANG Lei | 2024 | Science China(Technological Sciences)2024，67，1： | 0 |
| 19 | Shock-Resistant and Energy-Absorbing Properties of Bionic NiTi Lattice Structure Manufactured by SLM显示文摘Each specific structure of organisms is the best choice under specific circumstances.The excellent characteristic structures of these organisms have great application potential in the design and multi-functional optimization of energy-absorbing structures such as vehicle collisions,satellite landings,and military equipment.In this paper,using the principle of structural bionics,using the advantages of the honeycomb structure and the light weight and high strength of beetle elytra,four bionic lattice structures are studied:CH,ZPRH,SCH and IBE.Using NiTi shape memory alloy,a unique material as the base material,samples are prepared using selective laser melting(SLM)technology.By comparing the test results of the quasi-static compression test with the results of the numerical simulation,it is found that compared with the other three bionic lattice structures,the SCH structure has the best energy absorption effect in the effective stroke in the test,and the specific energy absorption can reach 6.32 J/g.ZPRH,SCH,and IBE structures not only have good and stable deformation behavior,but also have excellent impact resistance and shape memory properties.The design of these structures provides a reference for the design of anti-shock cushioning structures with self-recovery functions in the future. | Zhenglei Yu Renlong Xin Zezhou Xu Luming Sha Lixin Chen Yining Zhu Ping Liang Zhihui Zhang Zhenze Liu Qing Cao | 2022 | Journal of Bionic Engineering2022，19，6： | 0 |
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