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| 1 | Self-Healing Liquid Metal Magnetic Hydrogels for Smart Feedback Sensors and High-Performance Electromagnetic Shielding显示文摘Hydrogels exhibit potential applications in smart wearable devices because of their exceptional sensitivity to various external stimuli.However,their applications are limited by challenges in terms of issues in biocompatibility,custom shape,and self-healing.Herein,a conductive,stretchable,adaptable,self-healing,and biocompatible liquid metal GaInSn/Ni-based composite hydrogel is developed by incorporating a magnetic liquid metal into the hydrogel framework through crosslinking polyvinyl alcohol(PVA)with sodium tetraborate.The excellent stretchability and fast self-healing capability of the PVA/liquid metal hydrogel are derived from its abundant hydrogen binding sites and liquid metal fusion.Significantly,owing to the magnetic constituent,the PVA/liquid metal hydrogel can be guided remotely using an external magnetic field to a specific position to repair the broken wires with no need for manual operation.The composite hydrogel also exhibits sensitive deformation responses and can be used as a strain sensor to monitor various body motions.Additionally,the multifunctional hydrogel displays absorption-dominated electromagnetic interference(EMI)shielding properties.The total shielding performance of the composite hydrogel increases to~62.5 dB from~31.8 dB of the pure PVA hydrogel at the thickness of 3.0 mm.The proposed bioinspired multifunctional magnetic hydrogel demonstrates substantial application potential in the field of intelligent wearable devices. | Biao Zhao Zhongyi Bai Hualiang Lv Zhikai Yan Yiqian Du Xiaoqin Guo Jincang Zhang Limin Wu Jiushuai Deng David Wei Zhang Renchao Che | 2023 | Nano-Micro Letters2023，15，6： | 3 |
| 2 | Three dimensional nano-LiMn_(0.6)Fe_(0.4)PO_4@C/CNT as cathode materials for high-rate lithium-ion batteries显示文摘Three dimensional(3D) nano-LiMn_(0.6)Fe_(0.4)PO_4@C/CNT composite was successfully synthesized by an oleylamine-assisted solvothermal method. The prepared composite showed excellent electrochemical performance, especially superior high rate capability. It could deliver a specific discharge capacity of103.1 mAh/g, even at 80 C. The superior high rate performance of the as-prepared LiMn_(0.6)Fe_(0.4)PO_4@C/CNT electrode is attributed to its unique 3D conducting network:(1) the prepared LiMn_(0.6)Fe_(0.4)PO_4@C active particles were in nano-scale with a size of 30-50 nm;(2) LiMn_(0.6)Fe_(0.4)PO_4 nanoparticles were uniformly coated by amorphous carbon with a thickness of 3 nm;(3) the graphitized conductive CNTs were dispersed homogenously among the LiMn_(0.6)Fe_(0.4)PO_4@C active particles. The synergistic effect of the nanoscale amorphous carbon coated LiMn_(0.6)Fe_(0.4)PO_4@C active particles and the graphitized CNTs reduces the diffusion path of the lithium ions and benefits the transference ability of electron. | Huan Zhang Zhikai Wei Jinjin Jiang Lei Wang Qi Wan Tao Chen Meizhen Qu Mianzhong Chen | 2018 | Journal of Energy Chemistry2018，27，2： | 2 |
| 3 | Large Signal Statistical Model Oriented Parameter Extraction Method for GaN High Electron Mobility Transistors显示文摘Efficient parameter extraction method is essential to establish large signal statistical model. This paper presents an automatic parameter extraction method of I-V model for Gallium nitride(GaN) High electron mobility transistors(HEMTs) large signal statistical model. To accurate modeling the statistical characterization, all of 53 parameters in an I-V model are considered. In order to realize automatic parameter extraction, the model parameters are divided into blocks according to their physical meaning to reduce the complexity of the I-V model. Different parameter blocks are extracted separately by fitting the pulsed I-V transfer characteristic curves of the device at different quiescent bias points. A large signal statistical model for 0.25μm GaN HEMTs process has been established by using the proposed method after measuring 34 GaN HEMTs from 10 batches. The results show that the large-signal performances(Output power and Power added efficiency) can be reproduced with high accuracy by the proposed statistical model. | YU Xuming XU Yuehang WEN Zhang CHEN Zhikai HONG Wei | 2017 | Chinese Journal of Electronics2017，26，6： | 2 |
| 4 | Effect of ZnO nanoparticles doped graphene on static and dynamic mechanical properties of natural rubber composites显示文摘 | Yong Lin Yizhong Chen Zhikai Zeng Jiarong Zhu Yong Wei Fucheng Li Lan Liu | 2014 | Composites Part A2014，，： | 1 |
| 5 | Prestin-Mediated Frequency Selectivity Does not Cover Ultrahigh Frequencies in Mice显示文摘In mammals,the piezoelectric protein,Prestin,endows the outer hair cells(OHCs)with electromotility(eM),which confers the capacity to change cellular length in response to alterations in membrane potential.Together with basilarmembrane resonance and possible stereociliary motility,Prestin-based OHC eM lays the foundation for enhancing cochlear sensitivity and frequency selectivity.However,it remains debatable whether Prestin contributes to ultrahigh-frequency hearing due to the intrinsic nature of the cel's low-pass features.The low-pass_property of mouse OHC eM is based on the finding that eM magnitude dissipates within the frequency bandwidth of human speech.In this study,we examined the role of Prestin in sensing broad-range frequencies(4-80 kHz)in mice that use ultrasonic hearing and vocalization(to>100 kHz)for social communication.The audiometric measurements in mice showed that ablation of Prestin did not abolish hearing at frequencies>40 kHz.Acoustic associative behavior tests confirmed that Prestin-knockout mice can learn ultrahigh-frequency sound-coupled tasks,similar to control mice.Ex vivo cochlear Ca2+imaging experiments demonstrated that without Prestin,the OHCs still exhibit ultrahigh-frequency transduction,which in contrast,can be abolished by a universal cation channel blocker,Gadolinium.In vivo salicylate treatment disrupts hearing at frequencies<40 kHz but not ultrahigh-frequency hearing.By pharmacogenetic manipulation,we showed that specific ablation of the OHCs largely abolished hearing at frequencies>40 kHz.These findings demonstrate that cochlear OHCs are the target cells that support ultrahigh-frequency transduction,which does not require Prestin. | Jie Li Shuang Liu Chenmeng Song Tong Zhu Zhikai Zhao Wenzhi Sun Yi Wang Lei Song Wei Xiong | 2022 | Neuroscience Bulletin2022，38，7： | 1 |
| 6 | Prevalence of Resistance to Macrolide, Lincosamide, and Streptogramin Antibiotics in Staphylococcus Epidermidis Isolates from a Chinese Hospital显示文摘 | Ning Jia Maohu Lin Zhikai Xu Hua Wei Qunxing An Liyan Bai | 2006 | Journal of US-China Medical Science2006，3，5： | 1 |
| 7 | Effect of site-directed PEGylation of trichosanthin on its biological activity, immunogenicity, and pharmacokinetics显示文摘 | Qunxing An Yingfeng Lei Ning Jia Xianqing Zhang Yinlan Bai Jing Yi Rui Chen Aijun Xia Jing Yang Sanhua Wei Xiaodong Cheng Ailing Fan Shijie Mu Zhikai Xu | 2007 | Biomolecular Engineering2007，，6： | 1 |
| 8 | α-MnO2 nanorods grown in situ on graphene as catalysts for Li-O2 batteries with excellent electrochemical performance显示文摘 | Cao Yong Wei Zhikai He Jiao | 2012 | Energy & Environmental Science2012，5，12： | 1 |
| 9 | Mapping the antigenic determinants and reducing the immunogenicity of trichosanthin by site-directed mutagenesis显示文摘 | Qunxing An Sanhua Wei Shijie Mu Xianqing Zhang Yingfeng Lei Wei Zhang Ning Jia Xiaodong Cheng Ailing Fan Zhidong Li Zhikai Xu | 2006 | Journal of Biomedical Science2006，，5： | 1 |
| 10 | Comparing the accuracy of Demirjian and Nolla methods and establishing a new method for dental age estimation in northeastern Chinese children显示文摘Dental age estimation plays an important role in the field of clinic medicine and forensic medicine.The Demirjian and Nolla methods are common scoring methods for dental age estimation but there was no research about the comparison of accuracy of these two methods in northeastern Chinese children.Hence,in this study,we compared the accuracy of these two methods to explore more suitable method for our studied population.We collected 535 orthopantomograms from northern Chinese children aged from 6 to 15 years and divided them into training dataset and testing dataset according to the ratio of 7:3.The dental age of training dataset were estimated using Demirjian and Nolla methods,respectively.The results suggested that the mean differences of these two methods were 0.24 and−0.40 years,and mean absolute difference were 0.65 and 0.59 years.Then to further improve the accuracy of dental age assessment,the new improved formulas and dental age conversion tables were established after analyzing the relationship between the sum scores based on Nolla method and chronology age in training dataset.According to the new method used in testing dataset,the minimum value of mean difference(0.00)and mean absolute difference(0.49)were obtained,which are largely smaller than that of Demirjian and Nolla methods.The new developed method and dental age conversion scales may be more suitable dental age estimation method for northeastern Chinese children. | Dan Wen Zhiyu Ding Zhikai Tian Wenshuang Wu Weifeng Qu Wei He Chudong Wang Jienan Li Lagabaiyila Zha Ying Liu | 2022 | Forensic Sciences Research2022，7，4： | 0 |
| 11 | Differential diagnostic value of CT scan minimum attenuation values in adrenal adenomas and non-adenomas显示文摘 | Wu Ying Zhu Miaoping Han Zhijiang Wei Peiying Lei Zhikai | 2017 | 中华内分泌外科杂志2017，11，3： | 0 |
| 12 | In-situ grown Ni Co bimetal anchored on porous straw-derived biochar composites with boosted microwave absorption properties显示文摘With the gradually increasing protection awareness about electromagnetic pollution,the demand for absorbing materials with renewability and environmental friendliness has attracted widespread attention.In this work,composites consisting of straw-derived biochar combined with NiCo alloy were successfully fabricated through high-temperature carbonization and subsequent hydrothermal reaction.The electromagnetic parameters of the porous biocarbon/NiCo composites can be effectively modified by altering their NiCo content,and their improved absorbing performance can be attributed to the synergy effect of magnetic-dielectric characteristics.An exceptional reflection loss of-27.0 dB at 2.2 mm thickness and an effective absorption bandwidth of 4.4 GHz(11.7-16.1 GHz)were achieved.These results revealed that the porous biocarbon/NiCo composites could be used as a new generation absorbing material because of their low density,light weight,excellent conductivity,and strong absorption. | Yuanyuan Zhou Zhongyi Bai Xiangyang Yang Wei Liu Bingbing Fan Zhikai Yan Xiaoqin Guo | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，3： | 0 |
| 13 | Electrocatalytic oxidation of 5-hydroxymethylfurfural for sustainable 2,5-furandicarboxylic acid production-From mechanism to catalysts design显示文摘Catalytic conversion of biomass-based platform chemicals is one of the significant approaches to utilize renewable biomass resources.2,5-Furandicarboxylic acid(FDCA),obtained by an electrocatalytic oxidation of 5-hydroxymethylfurfural(HMF),has attracted extensive attention due to the potential of replacing terephthalic acid to synthesize high-performance polymeric materials for commercialization.In the present work,the pHdependent reaction pathways and factors influencing the degree of functional group oxidation are first discussed.Then the reaction mechanism of HMF oxidation is further elucidated using the representative examples.In addition,the emerging catalyst design strategies(defects,interface engineering)used in HMF oxidation are generalized,and structure-activity relationships between the abovementioned strategies and catalysts performance are analyzed.Furthermore,cathode pairing reactions,such as hydrogen evolution reaction,CO_(2) reduction reaction(CO_(2)RR),oxygen reduction reaction,and thermodynamically favorable organic reactions to lower the cell voltage of the electrolysis system,are discussed.Finally,the challenges and prospects of the electrochemical oxidation of HMF for FDCA are presented,focusing on deeply investigated reaction mechanism,coupling reaction,reactor design,and downstream product separation/purification. | Xiaoli Jiang Wei Li Yanxia Liu Lin Zhao Zhikai Chen Lan Zhang Yagang Zhang Sining Yun | 2023 | SusMat2023，3，1： | 0 |
| 14 | Anti-inflammatory spirobisnaphthalene natural products from a plant-derived endophytic fungus Edenia gomezpompae显示文摘Spirobisnaphthalenes comprise a relatively rare family of natural products that are normally isolated from fungi and occasionally from plants.Here we reported the discovery of seven new preussomerintype spirobisnaphthalenes,preussomerins YT1-YT7(1-7),and seven known ones(8-14),from the endophytic fungus Edenia gomezpompae,enriching the structural diversity of this family of natural products.Their structures were established by 1 D and 2 D NMR spectroscopy,HRESIMS analysis and comparison with previously reported compounds,with the absolute configurations of compounds 1 and2 being further confirmed by single-crystal X-ray diffraction using Cu Ka radiation.The antiinflammatory activities of all isolates were assessed by measuring the production of NO in LPS-induced RAW264.7 macrophage cells.Among them,compounds 8 and 13 exhibited potent inhibitory activities on the production of NO,with IC50 values of 2.61 and 1.32μmol/L,respectively. | Yingzi Tan Zhikai Guo Mengyue Zhu Jing Shi Wei Li Ruihua Jiao Renxiang Tan Huiming Ge | 2020 | Chinese Chemical Letters2020，31，6： | 0 |
| 15 | OsBLS6.2:A rice bacterial leaf streak resistance gene identified by GWAS and RNA-seq显示文摘Bacterial leaf streak(BLS),caused by Xanthomonas oryzae pv.oryzicola(Xoc),is a bacterial disease affecting rice production in Asia and Africa,whose severity is expected to increase with climate change.Identification of new quantitative-trait loci(QTL)or resistance genes for BLS resistance is essential for developing resistant rice.A genome-wide association study to identify QTL associated with BLS resistance was conducted using phenotypic and genotypic data from 429 rice accessions.Of 47 QTL identified,45 were novel and two co-localized with previously reported QTL or genes conferring BLS resistance.qBLS6.2 on chromosome 6 explained the greatest phenotypic variation.Combined analysis of differential expression and annotations of predicted genes near qBLS6.2 based on haplotype and disease phenotype identified OsBLS6.2(LOC_Os06g02960)as a candidate gene for qBLS6.2.OsBLS6.2 knockout plants showed higher resistance to Xoc than wild-type plants.Many other candidate genes for resistance to Xoc were identified. | Huabin Xie Chunzi Lin Wenyu Lu Zhikai Han Danhong Wei Xing Huo Tianjiao Li Jian Zhang Yongqiang He Chun Chen Hui Wang Tao Guo Jiafeng Wang | 2023 | The Crop Journal2023，11，6： | 0 |
| 16 | Application of Intravenous Indwelling Needle in Undergraduate's Pharmacology Teaching Experiment显示文摘In this study,an intravenous indwelling needle was placed in the central artery of rabbit ear for collecting blood.The results show that this method greatly improves the success rate of blood sampling and well controls the experimental time.The students'unanimous feedback was that the method is simple and easy to operate,which is of great help to the stability of the experimental results. | Yifei CHEN Jun LU Jingchen WEI Linglin CHEN Liang LU Zhikai DAI Yongwen LI | 2020 | Medicinal Plant2020，11，6： | 0 |
| 17 | Protein phosphatase 6 (Pp6) is crucial for regulatory T cell function and stability in autoimmunity显示文摘Regulatory T(T_(reg))cells constitute a dynamic population that is critical in autoimmunity.T_(reg) cell therapies for autoimmune diseases are mainly focused on enhancing their suppressive activities.However,recent studies demonstrated that certain inflammatory conditions induce T_(reg) cell instability with diminished FoxP3 expression and convert them into pathogenic effector cells.Therefore,the identification of novel targets crucial to both T_(reg) cell function and plasticity is of vital importance to the development of therapeutic approaches in autoimmunity.In this study,we found that conditional Pp6 knockout(cKO)in T_(reg) cells led to spontaneous autoinflammation,immune cell activation,and diminished levels of FoxP3 in CD4^(+)T cells in mice.Loss of Pp6 in T_(reg) cells exacerbated two classical mouse models of T_(reg)-related autoinflammation.Mechanistically,Pp6 deficiency increased CpG motif methylation of the FoxP3 locus by dephosphorylating Dnmt1 and enhancing Akt phosphorylation at Ser473/Thr308,leading to impaired FoxP3 expression in T_(reg) cells.In summary,our study proposes Pp6 as a critical positive regulator of FoxP3 that acts by decreasing DNA methylation of the FoxP3 gene enhancer and inhibiting Akt signaling,thus maintaining T_(reg) cell stability and preventing autoimmune diseases. | Wei Cai Junxun Zhang Hong Zhou Xiangxiao Li Fangzhou Lou Yang Sun Zhenyao Xu Jing Bai Qianqian Yin Zhikai Wang Libo Sun Xiaojie Cai Sibei Tang Yue Wu Li Fan Hong Wang Honglin Wang Qun Li | 2022 | Genes & Diseases2022，9，2： | 0 |
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