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| 1 | The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters显示文摘最近的研究在众多的生物过程增加了我们长 noncoding RNA (lncRNAs ) 的理解,但是很少在体的房间 reprogramming 检验了他们的角色。通过表示介绍并且功能的屏蔽,我们鉴别了大 intergenic noncoding RNA p21 (lincRNA-p21 ) 损害 reprogramming。尤其是, lincRNA-p21 被 p53 导致,但是不在 reprogramming 支持 apoptosis 或房间老朽。相反, lincRNA-p21 与 H3K9 methyltransferase SETDB1 和维护 DNA methyltransferase DNMT1 联系,它被 RNA 有约束力的蛋白质 HNRNPK 便于。因而, lincRNA-p21 由在 pluripotency 基因倡导者支撑 H3K9me3 或 CpG methylation 阻止 reprogramming。我们的结果在 reprogramming 提供卓见进 lncRNAs 的角色并且建立在 p53 和 heterochromatin 规定之间的一个新奇连接。 | Xichen Bao Haitao Wu Xihua Zhu Xiangpeng Guo Andrew P Hutchins Zhiwei Luo Hong Song Yongqiang Chen Keyu Lai Menghui Yin Lingxiao Xu Liang Zhou Jiekai Chen Dongye Wang Baoming Qin Jon Frampton Hung-Fat Tse Duanqing Pei Huating Wang Biliang Zhang Miguel A Esteban | 2015 | Cell Research2015，25，1： | 21 |
| 2 | Insult of gastroesophageal reflux on airway: clinical significance of pharyngeal nozzle显示文摘在到最糟的最高的注意在航线上吸烟以及薄雾侮辱的全球付钱的时间,所有人知道两个外长、显著。然而,包括许多医药人员,人们主要不知道 gastroesophageal 倒流(GER ) 怎么糟糕在我们的自己的航线上侮辱。GER 的症状通常被看作心痛和流回,它能主要被容忍。不管多么起来在它出现的地方,去的胃的内容相对地传递食管然后远侧的咽象苛评一样的鸟喙,用作一张嘴,以便生产众多微粒子并且到达oro鼻的洞并且另外引起的航线过敏鼻炎和气喘的攻击,甚至肺的实质损害。它将减少生活质量或甚至使受危险生活。内长的侮辱在呼吸系统出现,但是从消化的道发源的点不是众所周知的并且经常 undiagnosed 并且不正确地对待。导致的航线挑战是的 GER 一个可对待、预防的实体一旦诊断被做,好消除能通过 radiofrequency 或 fundoplication 借助于张开的贲门的生活方式调整,药,或固定被期望。作者王忠高博士承受了它为长并且症状在反倒流外科以后消失了 8 年。这是王忠高博士和他的队工作的一个演讲并且将引起注意到公众以便认出作为吸烟或薄雾从人的本身,然而并非从外面的环境发生的一个可对待的条件做的这个相对未知的实体。 | Zhonggao Wang Zhiwei Hu Jimin Wu Feng Ji Hongtao Wang Yungang Lai Xiang Gao Yachan Ning Chengchao Zhang Zhitong Li Weitao Liang Jianjun Liu | 2015 | Frontiers of Medicine2015，9，1： | 21 |
| 3 | Ultrasound-Assisted Transient Liquid Phase Bonding of Magnesium Alloy Using Brass Interlayer in Air显示文摘The microstructure evolution and oxide film behavior in ultrasound-assisted transient liquid phase(U-TLP) bonding of Mg alloy were investigated by applying different ultrasonic time at 460?C with brass interlayer in air. The results indicated that with increasing ultrasonic time, brass interlayer disappeared gradually and the Mg-Cu-Zn eutectic compounds were formed. The eutectic compounds in the joint decreased as the ultrasonic time increased further. The oxide removal process was divided into four steps. Continuous oxide film at the interface was partially fractured by ultrasonic vibration,and then suspended into liquid by undermining eutectic reaction. After that, the suspended oxide film was broken into small oxide fragments by ultrasonic cavitation effect, which was finally squeezed out of the joint by ultrasonic squeeze action. In addition, the mechanical properties of the joints were investigated. The maximum shear strength of the joint reached 105 MPa, which was 100% of base metal. | Zhiwei Lai Ruishan Xie Chuan Pan Xiaoguang Chen Lei Liu Wenxian Wang Guisheng Zou | 2017 | Journal of Materials Science & Technology2017，33，6： | 7 |
| 4 | Interfacial Structure and Formation Mechanism of Ultrasonic-assisted Brazed Joint of SiC Ceramics with Al—12Si Filler Metals in Air显示文摘Ultrasonic-assisted brazing of SiC ceramics was performed by filling with an Al—12Si alloy at a low temperature of 620 °C in air. The interfacial characteristics and formation mechanism were investigated. The joint shear strength reached 84–94 MPa using the ultrasonic time of 2–16 s. The fracture morphology showed that the fracture path initiated and propagated in the joint alloy. The thin film of amorphous SiO 2 that formed on the SiC surface was non-uniformly decomposed and diffused into the liquid Al—12Si alloy under the cavitation erosion effect of ultrasound. Abnormal isolated blocks of Al_2 SiO_5 compounds formed at the interface between Al—12Si and a thicker SiO_2 layer formed during the thermal oxidation treatment of the Si C ceramic. The SiO_2 layer on the Si C ceramic did not hinder or impair the wetting and bonding process, and a stronger bond could form between Al—12Si and SiO_2 or Si C in ultrasonicassisted brazing. | Xiaoguang Chen Ruishan Xie Zhiwei Lai Lei Liu Jiuchun Yan Guisheng Zou | 2017 | Journal of Materials Science & Technology2017，33，5： | 6 |
| 5 | Thermal comfort models and their developments:A review显示文摘In the past several years,thermal comfort,especially development and application of thermal comfort model,has been a research focus of building environment.Since the 1970s,a series of thermal comfort models based on people’s thermal sensation to environment have been established,and gradually became an important part of the field of thermal comfort research.In this review,the existing thermal comfort models are summarized from various perspectives,such as models applied in different environments like sleeping environment and outdoor environment.Besides,models used for different groups people,such as elderly and different races are discussed.In the part,adaptive models are mentioned.In additions,data-driven models were reviewed.This paper introduced the advantages and disadvantages of each model.Based on the above review,future research work of thermal comfort model is proposed. | Qiantao Zhao Zhiwei Lian Dayi Lai | 2021 | Energy and Built Environment2021，2，1： | 2 |
| 6 | Analysis of phase distribution for ceramic coatings formed by microarc oxidation on aluminum alloy 显示文摘 | Xue Wenbin Deng Zhiwei Lai Yongehun | 1998 | J Am Ceram Soc1998，81，5： | 1 |
| 7 | Analysis of Phase Distribution for Ceramic Coatings Formed by Microarc Oxidation on Aluminum Alloy显示文摘 | Wenbin Xue Zhiwei Deng Yonchun Lai Ruyi Chen | 1998 | J Am Ceram Soc1998，81，5： | 1 |
| 8 | Analysis of phase distribution for ceramic coatings formed by micro-arc oxidation on aluminum alloy显示文摘 | Xue Wenbin Deng Zhiwei Lai Yongchun | 1998 | J Am Ceram Soc1998，81，5： | 1 |
| 9 | Musical training induces functional plasticity in perceptual and motor networks: Insights from resting-state fmri显示文摘 | Luo Cheng Guo Zhiwei Lai Yongxiu | 2012 | PLoS One2012，7，36： | 1 |
| 10 | Analysis of phase distribution for ceramic coatings formed by micro-arc oxidation on aluminum alloy 显示文摘 | Xue Wenbin Deng Zhiwei Lai Yonchun | 1998 | J Am Ceram Soc1998，81，5： | 1 |
| 11 | Analysis of plasma distribution for ceramic coatings formed by micro-arc oxidation on aluminum alloy显示文摘 | XUE Wenbin DENG Zhiwei LAI Yongchun | 1998 | J Am Ceram Soc1998，81，5： | 1 |
| 12 | Analysis of phase distribution for ceramic coatings formed by micro-arc oxidation on aluminum alloy 显示文摘 | Xue Wenbin Deng zhiwei Lai Yongchun | 1998 | Journal of American Ceramic Society1998，81，5： | 1 |
| 13 | Analysis of phase distribution for ceramic coatings formed by microarc oxidation on aluminum alloy显示文摘 | XUE Wenbin DENG Zhiwei LAI Yonchun | 1998 | Journal of the American Ceramic Society1998，81，5： | 1 |
| 14 | hnage Segmentation Using Thresholding and Swarm Intelligence 显示文摘 | Ye Zhiwei I-Iu Zhengbing Lai Xudong Chen Hongwei | 2012 | Journal of Software2012，7，5： | 1 |
| 15 | Analysis of phase distribution for ceramic coatings formed by microarc oxidation on aluminum alloy 显示文摘 | Xue Wenbin Deng Zhiwei Lai Yonchun | 2005 | Journal of the American Ceramic Society2005，81，5： | 1 |
| 16 | Analysis of phase distribution for ceramic coatings formed by microarc oxidation on aluminum alloy 显示文摘 | Xue Wenbin Deng Zhiwei Lai Yongchun | 1998 | J Am Ceram Soc1998，81，5： | 1 |
| 17 | Expert Consensus on Diagnosis and Treatment of End-Stage Liver Disease Complicated with Infections显示文摘End-stage liver disease(ESLD)is a life-threatening clinical syndrome that markedly increases mortality in patients with infections.In patients with ESLD,infections can induce or aggravate the occurrence of liver decompensation.Consequently,infections are among the most common complications of disease progression.There is a lack of working procedure for early diagnosis and appropriate management for patients with ESLD complicated by infections as well as local and international guidelines or consensus.This consensus assembled up-to-date knowledge and experience across Chinese colleagues,providing data on principles as well as working procedures for the diagnosis and treatment of patients with ESLD complicated by infections. | Qin Ning Tao Chen Guiqiang Wang Dong Xu Yanyan Yu Qing Mao Taisheng Li Lanjuan Li Jun Li Xiaoju Lu Jiabin Li Zhiwei Li Wenhong Zhang Yonghong Xiao Qinghua Meng Yuqiang Mi Jia Shang Yunsong Yu Yingren Zhao Caiyan Zhao Hong Zhao Jianrong Huang Jie Peng Hong Tang Xiaoping Tang Jinhua Hu Bijie Hu Wei Guo Bo Zheng Baiyi Chen Yuexin Zhang Jia Wei Jifang Sheng Zhi Chen Minggui Wang Qing Xie Yuming Wang Fu-Sheng Wang Jinlin Hou Zhongping Duan Lai Wei Jidong Jia Chinese Society of Infectious Disease of Chinese Medical Association | 2022 | Infectious Diseases & Immunity2022，2，3： | 0 |
| 18 | Research on full-period acquisition method for diesel engine based on self-adaptive correlation analysis显示文摘Full-period signal acquisition of vibration signal plays a vital role in the health monitoring and fault diagnosis of modern industrial equipment group. The traditional full-period signal acquisition methods usually need not only a reference signal generated from special key phase device but also a reserved position, which is only suitable for a small number of particular equipment. A novel full-period signal acquisition method without key phase is proposed to construct the time-frequency method with strong energy concentration called the synchrosqueezing generalized S-Transform(SGST), combining together the Teager energy operator(TEO) and self-adaptive correlation analysis(SACA) based on the vibration signals of both gear and cylinder head. Actual vibration signals of diesel engine are employed to verify the feasibility and effectiveness of the proposed method by comparing with traditional method with special key phase device. By comparisons, the results show that full-period signal acquisition method without key phase has approximate accuracy for diesel engine under different working conditions. | 赵海朋 Mao Zhiwei Zhang Jinjie Lai Yuehua Wang Zijia Jiang Zhinong | 2020 | High Technology Letters2020，26，3： | 0 |
| 19 | Effect of 5-hydroxytryptamine Receptor in the Lower Esophageal Sphincter Regulation Mechanism显示文摘As a neurotransmitter and avascular active substance,the 5-hydroxytryptamine(5-HT,serotonin)is widely distributed in the central nervous system and surrounding tissues.The 5-HT can play its role by acting on its corresponding 5-HT receptor.Nowadays,the 5-HT receptor can be classified into seven,according to different signal transduction method of receptors,the 5-HT3 receptor belongs to the ligandgated ion channels,while other six 5-HT receptors are involved into the G protein-coupled receptors and play the biological role by binding to specific G protein-coupled receptors(GPCRs)on the surface of the cell membrane.The 5-HT plays an important role in the brain-gut information transmission and studies showed that the physiological stimulations like having meals,and pathological stimulations like ischemia and stress could promote the release of the 5-HT.In the gastrointestinal tract,the 5-HT is closely related to gastrointestinal sensitivity,gastrointestinal movement and secretion regulation,as well as many gastrointestinal dysfunction disorders,such as gastrointestinal power and visceral sensitivity abnormality and abnormalities of brain-gut axis. | Hefei Li Junfeng Liu Xixuan Zhang Zhiwei Lai Zhen Gao Chuntao Song | 2019 | Proceedings of Anticancer Research2019，3，6： | 0 |
| 20 | Application of statistical analysis of sample size:How many occupant responses are required for an indoor environmental quality(IEQ)field study显示文摘Determining required sample size is one of the critical pathways to reproducible,reliable and robust results in human-related studies.This paper aims to answer a fundamental but often overlooked question:what sample size is required in surveys of occupant responses to indoor environmental quality(IEQ).The statistical models are introduced in order to promote determining required sample size for various types of data analysis methods commonly used in IEQ field studies.The Monte Carlo simulations are performed to verify the statistical methods and to illustrate the impact of sample size on the study accuracy and reliability.Several examples are presented to illustrate how to determine the value of the parameters in the statistical models based on previous similar research or existing databases.The required sample size including“worst”and“optimal”cases in each condition is obtained by this method and references.It is indicated that 385 is a“worst case”sample size to be adequate for a subgroup analysis,while if the researcher has an estimate of the study design and outcome,the“optimal case”sample size can potentially be reduced.When the required sample size is not achievable,the uncertainty in the result can properly interpret via a confidence interval.It is hoped that this paper would fill in the gap between statistical analysis of sample size and IEQ field research,and it can provide a useful reference for researchers when planning their own studies. | Heng Du Zhiwei Lian Li Lan Dayi Lai | 2023 | Building Simulation2023，16，4： | 0 |
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