| 1 | Closer:Scalable Load Balancing Mechanism for Cloud Datacenters显示文摘Cloud providers(e.g.,Google,Alibaba,Amazon)own large-scale datacenter networks that comprise thousands of switches and links.A loadbalancing mechanism is supposed to effectively utilize the bisection bandwidth.Both Equal-Cost Multi-Path(ECMP),the canonical solution in practice,and alternatives come with performance limitations or significant deployment challenges.In this work,we propose Closer,a scalable load balancing mechanism for cloud datacenters.Closer complies with the evaluation of technology including the deployment of Clos-based topologies,overlays for network virtualization,and virtual machine(VM)clusters.We decouple the system into centralized route calculation and distributed route decision to guarantee its flexibility and stability in large-scale networks.Leveraging In-band Network Telemetry(INT)to obtain precise link state information,a simple but efficient algorithm implements a weighted ECMP at the edge of fabric,which enables Closer to proactively map the flows to the appropriate path and avoid the excessive congestion of a single link.Closer achieves 2 to 7 times better flow completion time(FCT)at 70%network load than existing schemes that work with same hardware environment. | Zixi Cui Pengshuai Cui Yuxiang Hu Julong Lan Fang Dong Yunjie Gu Saifeng Hou | 2021 | China Communications2021，18，4： | 0 |
| 2 | Diagnostic accuracy and safety of Dermatophagoides pteronyssinus extracts used for skin prick test显示文摘Background:Dermatophagoides pteronyssinus is a common allergen causing allergic diseases in China.The aim of this study was to evaluate the efficacy and safety of D.pteronyssinus extracts produced by Peking Union Medical College Hospital(PUMCH)for the skin prick test(SPT)in the diagnosis of D.pteronyssinus allergy.Methods:A total of 910 subjects with allergic diseases were prescribed D.pteronyssinus SPT and specific sIgE(sIgE)test among the Outpatients of Department of Allergy,PUMCH from August 10,2015 to August 30,2017.Receiver operating characteristic curve(ROC)analysis was performed according to the results of D.pteronyssinus-sIgE detection.The accuracy of D.pteronyssinus extracts used for SPT in the diagnosis of D.pteronyssinus allergy was evaluated under different cutoff values.Adverse events after SPT were recorded to evaluate safety.Results:There were 796 and 618 subjects in the full analysis set(FAS)and the per protocol set(PPS),respectively.The areas under the curve of FAS and PPS were 0.871 and 0.873,respectively.According to the ROC of PPS,the optimal and 95%specificity diagnostic cutoff values of D.pteronyssinus SPT mean wheal diameter were 3.25 and 3.75 mm,respectively.No adverse events occurred.Conclusion:The extracts of D.pteronyssinus for SPT were simple,highly accurate,and safe and should be considered for recommendation in the clinical diagnosis of D.pteronyssinus allergy. | Rui Tang Xiaohong Lyu Yuxi Liu Ruiqi Wang Lianglu Wang Hong Li Jinlyu Sun Yuxiang Zhi Jianqing Gu Kai Guan Liping Wen Zixi Wang Lisha Li Le Cui Yingyang Xu Junxiong Zhou Tao Xu Jia Yin | 2022 | Chinese Medical Journal2022，135，21： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员