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| 1 | Near-infrared fluorescence guided esophageal reconstructive surgery: A systematic review显示文摘BACKGROUND After an esophagectomy, the stomach is most commonly used to restore continuity of the upper gastrointestinal tract. These esophago-gastric anastomoses are prone to serious complications such as leakage associated with high morbidity and mortality. Graft perfusion is considered to be an important predictor for anastomotic integrity. Based on the current literature we believe Indocyanine green fluorescence angiography(ICGA) is an easy assessment tool for gastric tube(GT) perfusion, and it might predict anastomotic leakage(AL).AIM To evaluate feasibility and effectiveness of ICGA in GT perfusion assessment and as a predictor of AL.METHODS This study was designed according to the PRISMA guidelines and registered in the PROSPERO database. PubMed and EMBASE were independently searched by 2 reviewers for studies presenting data on intraoperative ICGA GT perfusion assessment during esophago-gastric reconstruction after esophagectomy.Relevant outcomes such as feasibility, complications, intraoperative surgical changes based on ICGA findings, quantification attempts, anatomical data and the impact of ICGA on postoperative anastomotic complications, were collected by 2 independent researchers. The quality of the included articles was assessed based on the Methodological Index for Non-Randomized Studies. The 19 included studies presented data on 1192 esophagectomy patients, in 758 patients ICGA was used perioperative to guide esophageal reconstruction.RESULTS The 19 included studies for qualitative analyses all described ICGA as a safe and easy method to evaluate gastric graft perfusion. AL occurred in 13.8% of the entire cohort, 10% in the ICG guided group and 20.6% in the control group(P <0.001). When poorly perfused cases are excluded from the analyses, the difference in AL was even larger(AL well-perfused group 6.3% vs control group 20.5%, P <0.001). The AL rate in the group with an altered surgical plan based on the ICG image was 6.5%, similar to the well perfused group(6.3%) and significantly less than the poorly perfused group(47.8%)(P < 0.001), suggesting that the technique is able to identify and alter a potential bad outcome.CONCLUSION ICGA is a safe, feasible and promising method for perfusion assessment. The lower AL rate in the well perfused group suggest that a good fluorescent signal predicts a good outcome. | Elke Van Daele Yves Van Nieuwenhove Wim Ceelen Christian Vanhove Bart P Braeckman Anne Hoorens Jurgen Van Limmen Oswald Varin Dirk Van de Putte Wouter Willaert Piet Pattyn | 2019 | World Journal of Gastrointestinal Oncology2019，11，3： | 3 |
| 2 | High genetic diversity and connectivity in a common mesopelagic fish of the Southern Ocean:the myctophid Electrona antarctica显示文摘 | Van De Putte A P Van Houdt J K J Maes G E | 2011 | Deep Sea Research Part II:Topical Studies in Oceanography2011，5960，： | 1 |
| 3 | New insights intothe surgical anatomy of the rectum: a review 显示文摘 | Willaert W Pattyn P Van De Putte D | 2011 | Acta Chir Belg2011，111，5： | 1 |
| 4 | Isolation, characterization and UVstimulated expression of two family of gene encoding polypeptide of related structure in human epidermal keratinocytes显示文摘 | Kartasva T Van de Putte P | 1998 | Mol Cell Bio1998，8，： | 1 |
| 5 | New insights in DNA repair preferential repair of transcriptionally active DNA显示文摘 | Terleth C van de putte P Brouwer J | 1991 | Mutagenesis1991，6，2： | 1 |
| 6 | Content of potentially anticarcinogenic flavonoids of tea infusions, wines, and fruit' juices显示文摘 | Hertog M G L Hollman P C H van de Putte B | 1993 | Journal of Agricultural and Food Chemistry1993，41，： | 1 |
| 7 | Bedside gastric ultrasonography to guide anesthetic management in a nonfasted emergency patient显示文摘 | VAN DE PUTTE P | 2013 | J ClinAnesth2013，25，2： | 1 |
| 8 | Gastric sonography in the severely obese surgical patient: a feasibility study显示文摘 | VAN DE PUTTE P PERLAS A | 2014 | Anesth Analg2014，119，5： | 1 |
| 9 | Basic biology and clinical application of specific cyclooxygenase-2 inhibitors显示文摘 | Crofford LJ Lipsky PE Brooks P Abramson SB Simon LS Van de Putte LB | 2000 | Arth Rheum2000，43，1： | 1 |
| 10 | Isolation, characterization, and UV- stimulated expression of two families of genes encoding polypeptides of related structure in human epidermal keratinocytes 显示文摘 | Kartasova T van de Putte P | 1998 | Mol Cell Biol1998，8，5： | 1 |
| 11 | Extending the phenotype of recurrent rearrangements of 16p11.2: Deletions in mentally retarded patients without autism and in normal individuals显示文摘 | E.K. Bijlsma A.C.J. Gijsbers J.H.M. Schuurs-Hoeijmakers A. van Haeringen D.E. Fransen van de Putte B.-M. Anderlid J. Lundin P. Lapunzina L.A. Pérez Jurado B. Delle Chiaie B. Loeys B. Menten A. Oostra H. Verhelst D.J. Amor D.L. Bruno A.J. van Essen R. Hord | 2009 | European Journal of Medical Genetics2009，，2： | 1 |
| 12 | In- flammatory consequences of lung ischemia- reperfusion injury and low-Pressure ventilation 显示文摘 | Cobelens M van Putte P Kavelaars A | 2009 | J Surg Res2009，153，2： | 1 |
| 13 | Aortic reoperation after freestanding ho- mograft and pulmonary autograft root replacement显示文摘 | Malvindi P G van Putte B P Leone A Heijmen R H Sehepens M A Morshuis W J | 2011 | Ann Thorac Surg2011，91，： | 1 |
| 14 | A 24 amino-acid polypeptide is essential for the biosynthesis of the coenzyme pyrroloquinoline-quinone显示文摘 | Goosen N Huinen RG van de Putte P | 1992 | J Bacteriol1992，174，4： | 1 |
| 15 | New insights into the surgical anatomy of the rectum:a review显示文摘 | Willaert W Pattyn P Van De Putte D | 2011 | Acta Chir Belg2011，111，5： | 1 |
| 16 | Development of osteoarthritic lesions in mice by 'metabolic' and 'mechanical' alterations in the knee joints 显示文摘 | van der Kraan P M Vitters E L van de Putte L B | 1989 | Am J Pathol1989，135，6： | 1 |
| 17 | The regulation of transcription initiation by integration host factor显示文摘 | Goosen N van de Putte P | 1995 | Mol Microbiol1995，16，： | 1 |
| 18 | Ultrasound assessment of gastriccontent and volume 显示文摘 | Van de Putte P Perlas A | 2014 | Br J Anaesth2014，113，1： | 1 |
| 19 | The role of affect and cognition in health decision making显示文摘 | Keer M van den putte B Neijens P | 2010 | Brit J Soci Psy- chol2010，49，1： | 1 |
| 20 | Ultrasound assessment ofgastric content and volume显示文摘 | VAN DE PUTTE P PERLAS A | 2014 | Br J Anaesth2014，113，1： | 1 |
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