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| 1 | 教育领域中的人工智能:概念辨析、应用隐忧与解决途径显示文摘人工智能飞速发展,在教育领域亦广泛应用。人工智能的出现极大地影响了教师教学,极大地改变了学习过程的发生机理和作用机制。人工智能与教育结合,“人工智能教育AIE”、“教育人工智能EAI”和“教育中的人工智能AIEd”三种概念被广泛使用,但学术研究领域对三种概念也产生了一定的误解。研究者需要在理清概念和内涵的基础上,全面审视人工智能对教育的变革,理智思考教育领域中人工智能在认知局限、伦理危机、评价偏差和教育风险上的若干隐忧。研究据此提出促进区域AI基础建设与数据协作、完善政府监督职责和领导力建设、倡导“政企学研”多方对象紧密合作、促进教师AI培训和专业发展等四方面建议,以期为教育研究者和实践者明确人工智能目前的近义概念、为促进我国教育领域的人工智能发展建言献策。 | 孟翀 王以宁 | 2021 | 现代远距离教育2021，，2： | 30 |
| 2 | 3G长期演进技术——E3G显示文摘E3G是针对新的频段和更高的业务能力的3G演进技术,其采用的技术仍然以蜂窝移动通信为基础,同时集成和融合多种无线技术。通过介绍各种通信技术和市场的发展,阐述了E3G技术特点和发展现状,分析了E3G对未来通信市场格局的影响。 | 胡海波 | 2006 | 世界电信2006，19，4： | 10 |
| 3 | NIR-II ?uorescence in vivo confocal microscopy with aggregation-induced emission dots显示文摘Significantly reduced tissue scattering of fluorescence signals in the second near-infrared(NIR-Ⅱ,1,000–1,700 nm)spectral region offers opportunities for large-depth in vivo bioimaging.Nowadays,most reported works concerning NIR-II fluorescence in vivo bioimaging are realized by wide-field illumination and 2D-arrayed detection(e.g.,via InGaAs camera),which has high temporal resolution but limited spatial resolution due to out-of-focus signals.Combining NIR-II fluorescence imaging with confocal microscopy is a good approach to achieve high-spatial resolution visualization of biosamples even at deep tissues.In this presented work,a NIR-II fluorescence confocal microscopic system was setup.By using a kind of aggregation-induced emission(AIE)dots as NIR-II fluorescent probes,800 lm-deep 3D in vivo cerebrovascular imaging of a mouse was obtained,and the spatial resolution at 700 lm depth could reach 8.78 lm.Moreover,the time-correlated single photon counting(TCSPC)technique and femtosecond laser excitation were introduced into NIR-II fluorescence confocal microscopy,and in vivo confocal NIR-II fluorescence lifetime microscopic imaging(FLIM)of mouse cerebral vasculature was successfully realized. | Wenbin Yu Bing Guo Hequn Zhang Jing Zhou Xiaoming Yu Liang Zhu Dingwei Xue Wen Liu Xianhe Sun Jun Qian | 2019 | Science Bulletin2019，64，6： | 10 |
| 4 | 自主创新导向下的TD-SCDMA与NGBWM务实发展战略思考显示文摘以TD-SCDMA既有进展、面临的挑战与NGBWM的发展走向为基础,重点论述了自主创新导向下的TD-SCDMA与NGBWM务实发展战略。 | 陈如明 | 2007 | 中国无线电2007，，1： | 7 |
| 5 | 细胞质膜可视化成像:聚集诱导发光(AIE)探针新用途显示文摘细胞质膜(PM)是指包围在细胞表面的一层极薄的膜,其基本作用是维护细胞内微环境的相对稳定,并参与同外界进行物质交换、能量和信息传递.此外,它还在细胞的生长、分裂及分化中起重要作用.PM的异常通常是多种疾病出现的重要标志,因此,实现在复杂系统中对PM的可视化成像是当前一个重要研究方向[1]. | 杨杰 李振 | 2019 | 有机化学2019，39，11： | 6 |
| 6 | 基于AIE效应的多重刺激响应性聚合物纳米微球的制备及其细胞示踪应用显示文摘基于AIE分子和智能响应性聚合物构筑的纳米材料,具有优良的AIE发光性能、环境刺激响应性和生物相容性,已在生命科学领域展现出诱人的应用前景.本研究通过ATRP活性聚合方法,以合成的TPE-BIB为引发剂,引发具有多刺激响应特性的N-[2-(二乙氨基)-乙基]丙烯酰胺单体聚合,成功制备具有温度/pH/CO2三重响应性的两亲性聚合物:TPE-g-PDEAEAM,并自组装形成约200nm的纳米微球.研究表明:这种聚合物纳米粒子具有优良的水溶性、单分散性、稳定性及优异的AIE发光特性.其相转变温度为60℃,溶液荧光对环境温度、pH及CO2均表现出快速敏感响应性能.同时,该纳米粒子表现出低细胞毒性,能够有效示踪HeLa细胞增殖至11代以上,有望作为一种活细胞荧光示踪探针材料. | 关晓琳 王林 李志飞 刘美娜 王凯龙 林斌 杨学琴 来守军 雷自强 | 2019 | 化学学报2019，77，10： | 6 |
| 7 | NIR Emission Nanoparticles Based on FRET Composed of AIE Luminogens and NIR Dyes for Two-photon Fluorescence Imaging显示文摘Near-infrared(NIR) nanoparticles(NPs) based on fluorescence resonance energy transfer(FRET) were prepared by coencapsulation of a red aggregation-induced emission(AIE) molecule, 2-(4-bromophenyl)-3-(4-(4-(diphenylamino)styryl)phenyl)fumaronitrile(TB), and a commercial NIR fluorescence dye, silicon 2,3-naphthalocyanine bis(trihexylsilyloxide)(NIR775) with an amphiphilic polymer poly(styrene-co-maleic anhydride)(PSMA). The surface of the NPs, PSMA@TB/NIR775, was modified with poly(ethylene glycol)(PEG) to increase the in vivo biocompatibility of the NPs. The PSMA@TB/NIR775 NPs showed a strong NIR(780 nm) narrow emission and excellent two-photon absorption property. Moreover, the NPs exhibited good monodispersity, stability, and low cytotoxicity.Under the excitation of a 1040 nm femtosecond(fs) laser, the emission peaks at 680 nm of TB and 780 nm of NIR775 excited by FRET were obtained. We utilized PSMA@TB/NIR775 NPs as fluorescent contrast agents for two-photon excited NIR microscopic imaging, and good NIR imaging effect of mouse brain vasculature was obtained with the imaging depth of about 150 μm. The FRET strategy by coencapsulating AIE molecule and NIR dye will be helpful in preparing more narrow emission NIR probes for deep-tissue biological imaging. | Lei-Jing Liu Wen Liu Guang Jia Zhi-Yuan Wu Bin Xu Jun Qian Wen-Jing Tian | 2019 | Chinese Journal of Polymer Science2019，37，4： | 4 |
| 8 | Electronic effect on the optical properties and sensing ability of AIEgens with ESIPT process based on salicylaldehyde azine显示文摘Two novel AIE-active salicylaldehyde azine(SAA) derivatives with a typical excited-state intramolecular proton transfer(ESIPT) process are prepared by introducing electron-withdrawing and donating groups at para-position of phenolic hydroxyl group(CN-SAA and TPA-SAA). The effect of the proton activity in SAA framework on their optical behaviors is investigated spectroscopically. The results from NMR and solvation measurements show that the proton of phenolic hydroxyl group has higher activity when there are electron-withdrawing groups, and the absorption and fluorescence spectra in buffers with different pH also provide the same results. After inviting F. as a nucleophilic probe, this proton activity difference in CN-SAA and TPA-SAA becomes more obvious. The potential application of both molecules is investigated. TPA-SAA exhibits good quantitative sensing ability towards F. with a fluorescence 'turn-on' mode, whereas the aggregates of TPA-SAA can selectively and sensitively detect Cu2+ in aqueous solution. From these results, a structure-property relationship is established: the occurrence of ESIPT process will become much easier when linking electron-withdrawing groups at the para-position of phenolic hydroxyl group(e.g., CN-SAA),and it is better to introduce electron-donating groups to enhance the sensing ability towards ions(e.g., TPA-SAA). This work will provide guidance for further design and preparation of AIE-active luminogens with ESIPT process for sensing applications. | Zhiming Wang Fan Zhou Jing Wang Zujin Zhao Anjun Qin Zhenqiang Yu Ben Zhong Tang | 2018 | Science China Chemistry2018，61，1： | 3 |
| 9 | E3G技术——3GPP LTE和3GPP2 AIE的核心技术与标准化进展显示文摘演进型3G(E3G)技术是3GPP LTE(长期演进)和3GPP2 AIE(空中接口演进)项目的统称。这项技术名为“演进”,实则是一场技术“革命”。对两种演进型3G技术——3GPP LTE 和3GPP2 AIE的标准化进程、需求指标和核心技术作了简略的介绍。 | 沈嘉 | 2006 | 世界电信2006，19，4： | 3 |
| 10 | Rational Fabrication and Biomedical Application of Biomolecule-Conjugated AIEgens through Click Reaction显示文摘Recently,the issue of cancer has attracted extensive attention.Early diagnosis and timely therapy are important for cancer treatment.And lots of advanced fluorescent probes have been applied to cancer theranostics.However,the further development of these probes is limited by the disadvantages of poor targeting,weak sensitivity and photobleaching.Fortunately,the emergence of biomolecule-conjugated fluorescent probes with aggregationinduced emission properties has taken innovative impetus to the cancer theranostics.This review summarizes the rational fabrication and biomedical applications of biomolecule-conjugated A1E luminogens(AIEgens)based on'click reaction'over the past decade.In the meantime,the challenges of biomolecule-conjugated AIEgens in the field of biomedicine are also discussed. | Qiming Yuan Yong Cheng Xiaoding Lou Fan Xia | 2019 | Chinese Journal of Chemistry2019，37，10： | 3 |
| 11 | 机械变色有机材料作为传感器的应用显示文摘机械变色有机材料的研发是材料科学研究的一个热点。这种刺激响应的颜色或荧光光谱的变化有广泛的潜在应用价值,例如用于光学记录、存储、显示,用于制备密写墨水以及构建化学传感器、生物传感器、张力或压力传感器等。该文对其中的AIE有机物和非AIE机械变色有机物作为探针和传感器方面的应用加以介绍。 | 赵沛然 潘玉珍 | 2013 | 化学传感器2013，33，2： | 3 |
| 12 | 新生儿缺氧缺血性脑病电解质变化(附64例分析)显示文摘新生儿缺氧缺血性脑病电解质变化(附64例分析)泉州市儿童医院高璇璇,王素香新生儿缺氧缺血性脑病(HIE)可引起电解质代谢的紊乱,对本病的合理治疗不但可降低新生儿期的病死率,而且能减少神经系统的后遗症。为避免补液不当而加重脑损害,本文对1995年1月~... | 高璇璇 王素香 | 1996 | 福建医药杂志1996，18，2： | 3 |
| 13 | 具有聚集诱导发光性质的新型二芳基喹喔啉衍生物用于检测Hg^(2+)(英文)显示文摘荧光传感器由于具有高灵敏度和高选择性,在检测化学方面得到广泛的应用。本文合成了具有活性荧光团的二芳基喹喔啉衍生物(1~4),并对其进行表征。化合物3同时具有聚集诱导发光(AIE)特征的二芳基喹喔啉、和Hg2+具有特殊反应的1,3-二硫杂环戊二烯-2-硫酮基团,我们将这两个特征基团耦合在同一个化合物之中,从而构建了一类新的'开启'型汞离子荧光传感器。 | 王彬彬 刘磊 张圆圆 沈梁君 王乐佳 陈爱兵 冯浩彬 肖勋文 | 2018 | 化学通报2018，81，6： | 2 |
| 14 | Bioactivated in vivo assembly(BIVA)peptide-tetraphenylethylene(TPE)probe with controllable assembled nanostructure for cell imaging显示文摘The emergence of fluorescent light-up molecular probe,which can specifically turn on their fluorescent in the presence of stimulation factors,has open up a new opportunity to advance biosensing and bioimaging.In this work,we designed and synthesized a peptide-AIE conjugate probe for cell imaging with controlled in situ assembled nanostructures.The modular designed probe is consisted of a selfassembled peptide-tetraphenylethene(TPE)motif,a fibroblast activation protein alpha(FAP-α)responsive motif,a hydrophilic motif and a targeting motif.The probe exhibits typically turn-on fluorescence property specifically triggered by FAP-α,which is a significant overexpressed membrane protein on pancreatic tumor cells.Interestingly,the peptide modified the TPE dramatically impacts the assembled nanostructure,which can be modulated by peptide sequences.As a result,the peptide FF(PhePhe)modification of TPE as the self-assembled motif provides a suitable balance of the probe with lightup property and nanofiber assembled structure in situ.Finally,our probe could effectively detect the FAP-αon tumor cells with high specificity.Meantime,the nanofibers in situ assembled on the surface of CAFs enhanced the probe accumulation and prolonged the retention for cell imaging.We envision that this study may inspire new insights into the design of nanostructure controlled AIE light-up bio-probe. | Shizhao Lu Xiaoyan Guo Fangling Zhang Xiaodong Li Meishuai Zou Li-Li Li | 2021 | Chinese Chemical Letters2021，32，6： | 2 |
| 15 | Tetraphenylethylene-Based Emissive Supramolecular Metallacages Assembled by Terpyridine Ligands显示文摘We report the preparation and emission properties of tetraphenylethylene(TPE)-based metallacages with aggregation-induced emission(AIE)activities through coordination-driven self-assembly.Two supramolecular cages,[Zn6LA3]and[Zn6LB3],were assembled via TPE-decorated terpyridine(tpy)ligands,LA and LB,respectively,with Zn(II)ions.We performed a subtle change by introducing extra alkyne connectivity into LB to increase the degree of conjugation and geometric constraint,compared with LA.As a result,we obtained a highly emissive cage,[Zn6LB3],even in a dilute solution. | Meng Li Shan Jiang Zhe Zhang Xin-Qi Hao Xin Jiang Hao Yu Pingshan Wang Bin Xu Ming Wang Wenjing Tian | 2020 | CCS Chemistry2020，2，4： | 2 |
| 16 | 聚集诱导发射型荧光分子探针研究进展显示文摘综述了四苯乙烯及其类似物在化学传感和生物探针方面的应用,并对其应用前景做了展望。 | 马钰程 齐春轩 马恒昌 | 2017 | 现代化工2017，37，11： | 2 |
| 17 | ESIPT-based AIE luminogens:Design strategies,applications,and mechanisms显示文摘In this review,we present a systematic and comprehensive summary of the recent development and applications of excited-state intramolecular proton transfer-based(ESIPT-based)aggregation-induced emission luminogens(AIEgens),a type of promising materials that inherit the advantages of ESIPT and AIE,such as large Stokes shift,excellent photostability,and low self-quenching.We first summarize the backbones that have been used to construct the ESIPT-based AIEgens and classify the constructed ones based on the relation between ESIPT and AIE unit.According to the sensing mechanisms and design strategies,we have reviewed the applications of ESIPT-based AIEgens in bioimaging,drug delivery systems,organic lightemitting diodes,photo-patterning,liquid crystal,and the detection of metal cations,anions,small molecules,biothiols,biological enzymes,latent fingerprinting,and so on.We have also reviewed the recent advances in the development of new theoretical methods for investigating molecular photochemistry in crystals and their applications in ESIPT-based AIEgens.We discussed the remaining challenges in this field and the issues that need to be addressed.We anticipate that this review can provide a comprehensive picture of the current condition of research in this field,and promote researchers to make more efforts to develop novel ESIPT-based AIEgens with new applications. | Panwang Zhou Keli Han | 2022 | Aggregate2022，3，5： | 2 |
| 18 | pH-responsive AIE-active Polyethylene-based Block Copolymers显示文摘A novel synthetic strategy towards pH-responsive aggregation-induced emission (AIE)-active tetraphenylethene (TPE)- functionalized polyethylene-based block copolymers is presented. Tris(3-(4-(l,2,2-triphenylvinyl)phenoxy)propyl)borane was used to initiate the polyhomologation of dimethylsulfoxonium methylide to afford well-defined a-TPE-ω-OH linear polyethylenes (PE). The terminal hydroxyl groups were transformed to atom transfer radical polymerization (ATRP) initiating sites by esterification with bromoisobutyryl bromide, followed by polymerization of rert-butyl acrylate (tBA) to provide TPE-PE-b-PtBA block copolymers. After hydrolysis of the rBu group to COOH group, the corresponding pH-responsive TPE-PE-b-PAA block copolymers were obtained. All synthesized block copolymers revealed AIE behavior either in solution or bulk. Due to the pH-responsivity of PAA chains, the aggregation state at different pH and consequently the fluorescence intensity changed. Also, the synthesized block copolymers exhibited ion-specificity fluorescence properties. | Yu Jiang Nikos Hadjichristidis | 2019 | Chinese Journal of Polymer Science2019，37，9： | 2 |
| 19 | cdma2000空中接口技术的演进显示文摘首先介绍了AIE阶段一的具体需求和主要的技术点,接着重点描述了AIE阶段二的具体需求、工作流程以及需要确定的解决方案,最后讨论了在融合过程中的资源分配和功率控制技术。 | 杜滢 桑立宏 | 2006 | 电信技术2006，，9： | 1 |
| 20 | 人工智能时代教育面临的挑战与解决路径探析显示文摘本研究对教育和人工智能交叉领域中的人工智能教育AIE、教育人工智能EAI、教育中的人工智能AlEd进行了阐释,阐述了国内外教育领域人工智能的发展状况,全面探讨了人工智能在教育领域中对教师、学生、教学过程和教学应用产生的新挑战,最后提出了人工智能时代教育发展的路径,以期为加快建设人工智能时代高质量教育体系提供思路,使人工智能服务于教育,但不离教育之本。 | 孙诗淇 | 2022 | 中国信息技术教育2022，，16： | 1 |
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