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| 1 | Mesenchymal stem cells: a new strategy for immunosuppression and tissue repair显示文摘间充质的干细胞(MSC ) 为治疗各种各样的疾病有大潜力,特别那些与织物有关损坏包含有免疫力的反应。各种各样的研究证明了 MSC 在 vitro 并且在 vivo 是强烈抑制免疫力的。我们的最近的研究证明了那未刺激的 MSC 确实不能免疫力的抑制;他们与 TNF- 伪, IL-1 伪或 IL-1 尾与激活的淋巴细胞的上层清液,或与 IFN- 纬的联合在刺激之上变得 potently 抑制免疫力。这观察表明在某些情形下面,煽动性的 cytokines 能实际上变得抑制免疫力。我们证明在调停 MSC 的免疫力的抑制的机制有一个种类变化:由告知 cytokine 的老鼠 MSC 的免疫力的抑制被氮的氧化物调停(没有) 而由告知 cytokine 的人的 MSC 的免疫力的抑制通过 indoleamine 被执行 2, 3-dioxygenase (伊多语) 。在有煽动性的 cytokines 的刺激之上,另外,老鼠和人的 MSC 分泌几白血球 chemokines 显然服务与 MSC 吸引有免疫力的房间进最近,在哪儿不或伊多语被预言很活跃。因此,由煽动性的刺激 cytokine 的 MSC 的免疫力的抑制经由 chemokines 的一致行动发生并且免疫者禁止没有或伊多语由 MSC 生产了。因此,我们的结果在对待有免疫力的回答导致的织物损害关于调停 MSC 的免疫力的抑制并且为 MSC 的更好的申请的机制提供新奇信息。 | Yufang Shi Gangzheng Hu Juanjuan Su Wenzhao Li Qing Chen Peishun Shou Chunliang Xu Xiaodong Chen Yin Huang Zhexin Zhu Xin Huang Xiaoyan Han Ningxia Xie Guangwen Ren | 2010 | Cell Research2010，20，5： | 72 |
| 2 | Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock显示文摘Inflammasomes 是触发 caspase-1 的激活和 interleukin-1β 的成熟的多蛋白质建筑群;(IL-1β) ,然而,这些建筑群的规定仍然保持糟糕描绘了。这里,我们显示出那氮的氧化物(没有) 禁止了调停 NLRP3 的 ASC pyroptosome 形成, caspase-1 激活和 IL-1β在从老鼠和人的 myeloid 房间的分泌物。同时,内长不否定地也源于 iNOS (没有 synthase 的可诱导的形式) 调整 NLRP3 inflammasome 激活。iNOS 的弄空响应 LPS 和 ATP 导致了不正常的线粒体的增加的累积,它为增加的 IL-1β 负责;生产和 caspase-1 激活。没有生产的 iNOS 缺乏或药理学抑制在 vivo 提高了 NLRP3 依赖的 cytokine 生产,因此在老鼠从导致 LPS 的败血增加死亡,它被 NLRP3 阻止缺乏。我们的结果因此经由线粒体的稳定作为 NLRP3 inflammasome 的一个批评否定管理者不识别。这研究有重要含意让新策略的设计控制 NLRP3 相关的疾病。 | Kairui Mao Shuzhen Chen Mingkuan Chen Yonglei Ma Yan Wang Bo Huang Zhengyu He Yan Zeng Yu Htl Shuhui Sun Jing Li Xiaodong Wu Xiangrui Wang Warren Strober Chang Chen Guangxun Meng Bing Sun | 2013 | Cell Research2013，23，2： | 59 |
| 3 | Focal depth research of earthquakes in China's Mainland: Implication for tectonics显示文摘Focal depth data of earthquakes in China's Mainland are processed and analyzed in this paper, as well as the relationship between the focal depths and large-scale tectonic structures. As a basic parameter for earthquakes, focal depth is used to investigate deep environment of seis-mogenic regions, tectonic backgrounds for concentration and release of seismic energy, the inner crustal deformation and its mechanic features. Depth data of 31282 ML≥2.0 events with 1st class and 2nd class precision in China's Mainland from Jan. 1, 1970 to May 31, 2000 are used to get spatial features of earthquakes distributed with depth and to provide average depth for each grid area throughout China. Researches show that the average depth (D) for all the earthquakes used in this paper is (16±7) km, and (13±6) km and (18±8) km for the events in eastern China and western China, respectively. The area with the deepest focal depth is located in southwest Xinjiang region, near the western and southwestern ends of the Tarim | ZHANG Guomin WANG Suyun LI Li ZHANG Xiaodong MA Hongsheng | 2002 | Chinese Science Bulletin2002，47，12： | 38 |
| 4 | Evaluation of a granulated formula for the nerve root type and vertebral artery type of cervical spondylosis:a multicenter,single-blind,randomized,controlled,phase Ⅲ clinical trial显示文摘OBJECTIVE:To evaluate the effectiveness and safety of cervical spondylosis formula granules in reducing the symptoms of patients with the nerve root type and the vertebral artery type of cervical spondylosis.METHODS:This was a multicenter, single-blind,randomized, controlled trial.From April 2002 to November 2003, 499 patients were randomly assigned to either the treatment or the control group.The treatment group was orally administered granules prepared with a formula for cervical spondylosis, while the control group was given Jingfukang granules.The treatment course was 1 month for both groups.RESULTS:In patients with the nerve root type of cervical spondylosis, the total effect rate in the treatment group(87.21%) was significantly higher than that in the control group(80.70%, P < 0.01).After the treatment period in both groups, the treatment group had a significantly greater rate of resolution of pain, numbness of the upper limbs, muscle strength of the upper limbs, and fatigue than the control group(all P < 0.05).In patients with the vertebral artery type of cervical spondylosis, the total effect rate in the treatment group(82.07%) was similar to that in the control group(71.21%, P >0.05).After the treatment period in both groups,the treatment group had a significantly greater rate of resolution of weakness of the waist and knees than the control group(P < 0.05).CONCLUSION:The cervical spondylosis formula granules significantly improve numbness, muscle strength, and fatigue, and reduce pain in patients with the nerve root type of cervical spondylosis,and improve the weakness of the waist and knees in patients with the vertebral artery type of cervical spondylosis. | Luo Xiaodong Wang Peng Li Zhe Liang De Huang Feng Liu Jinwen Chen Xinyu Hu Guoheng Fang Suting Zhang Huajian | 2017 | Journal of Traditional Chinese Medicine2017，37，2： | 28 |
| 5 | The variation in soil moisture and the appropriate groundwater table for desert riparian forest along the Lower Tarim River显示文摘基于在五年监视更低的 Tarim 河收集的数据,我们由使用变化(Cv ) 的系数的方法分析了土壤潮湿内容(SMC ) 和在 SMC,地下水表格深度(GWD ) 和植被之间的关系的可变性,皮尔森关联和回归。SMC 的可变性的结果显示它随 060 厘米的土壤层的土壤层 SMC 的深度的增加升起了与在在可变性显示出重要增加的 100260 厘米的土壤层的 SMC 相比是相对小的。SMC 和 GWD 在生态的水消遣在 Yingsu 横断和它水路的附近的地点展出了重要差别前后,特别在 100260 厘米的土壤层的 SMC 与 GWD 的重要上升显著地增加了并且在大约 4 m 的 GWD 到达了最大的价值。显著地随 100260 厘米的土壤层的 SMC 的增加改进的植物范围和种类差异,他们俩接近了最大的价值,当 SMC 是时, 92.3% 主要植物种类能成长 >10% 。沿着更低的 Tarim 河恢复荒芜的河边的森林的生态系统, GWD 必须被维持在 < 在水路并且在为这个干旱区域的其余部分的大约 4 m 的附近的 4 m。 | MA Xiaodong CHEN Yaning ZHU Chenggang LI Weihong | 2011 | Journal of Geographical Sciences2011，21，1： | 23 |
| 6 | Exosomes containing miR-21 transfer the characteristic of cisplatin resistance by targeting PTEN and PDCD4 in oral squamous cell carcinoma显示文摘 | Tao Liu Gang Chen Dawei Sun Minghui Lei Yongqiang Li Changming Zhou Xiaodong Li Wei Xue Hong Wang Chunjun Liu Jiang Xu | 2017 | Acta Biochimica et Biophysica Sinica2017，49，9： | 22 |
| 7 | Hydrometallurgical purification of metallurgical grade silicon显示文摘The effects of the particle size of ground metallurgical grade silicon (MG-Si), the sort of acids, and the type of stirring on the purified efficiency of MG-Si were investigated. It was found that a particle size less than 0.1 mm was most effective for acid leaching; the extraction yield of impurities was increased by 9% with HF leaching compared with HCl leaching and HNO3 leaching, and increased by 7% with ultrasonic stirring compared with mechanical stirring. The principle of hydrometallurgical purification of metallurgical grade silicon under ultrasonic fields was also discussed. | MA Xiaodong ZHANG Jian WANG Tongmin LI Tingju | 2009 | Rare Metals2009，28，3： | 20 |
| 8 | Modeling spatio-temporal distribution of soil moisture by deep learning-based cellular automata model显示文摘Soil moisture content (SMC) is a key hydrological parameter in agriculture,meteorology and climate change,and understanding of spatio-temporal distributions of SMC in farmlands is important to address the precise irrigation scheduling.However,the hybrid interaction of static and dynamic environmental parameters makes it particularly difficult to accurately and reliably model the distribution of SMC.At present,deep learning wins numerous contests in machine learning and hence deep belief network (DBN) ,a breakthrough in deep learning is trained to extract the transition functions for the simulation of the cell state changes.In this study,we used a novel macroscopic cellular automata (MCA) model by combining DBN to predict the SMC over an irrigated corn field (an area of 22 km^2) in the Zhangye oasis,Northwest China.Static and dynamic environmental variables were prepared with regard to the complex hydrological processes.The widely used neural network,multi-layer perceptron (MLP) ,was utilized for comparison to DBN.The hybrid models (MLP-MCA and DBN-MCA) were calibrated and validated on SMC data within four months,i.e.June to September 2012,which were automatically observed by a wireless sensor network (WSN) .Compared with MLP-MCA,the DBN-MCA model led to a decrease in root mean squared error (RMSE) by 18%.Thus,the differences of prediction errors increased due to the propagating errors of variables,difficulties of knowing soil properties and recording irrigation amount in practice.The sequential Gaussian simulation (s Gs) was performed to assess the uncertainty of soil moisture estimations.Calculated with a threshold of SMC for each grid cell,the local uncertainty of simulated results in the post processing suggested that the probability of SMC less than 25% will be difference in different areas at different time periods.The current results showed that the DBN-MCA model performs better than the MLP-MCA model,and the DBN-MCA model provides a powerful tool for predicting SMC in highly non-linear forms.Moreover,because modeling soil moisture by using environmental variables is gaining increasing popularity,DBN techniques could contribute a lot to enhancing the calibration of MCA-based SMC estimations and hence provide an alternative approach for SMC monitoring in irrigation systems on the basis of canals. | SONG Xiaodong ZHANG Ganlin LIU Feng LI Decheng ZHAO Yuguo YANG Jinling | 2016 | Journal of Arid Land2016，8，5： | 20 |
| 9 | Interface Migration between Martensite and Austenite during Quenching and Partitioning (Q&P) Process显示文摘Fe-0.2C-l.5Si-l.67Mn 钢受到熄灭并且划分(Q&P ) 进程,和在在提高的划分温度的马氏体和奥氏体之间的接口移植被观察。接口迁居在 constrainedparaequilibrium (用户终端设备) 被排除模型。基于“端点”由用户终端设备模型预言接口移植的热力学的条件被分析,也就是说,在在铁酸盐(martenisite ) 和奥氏体的铁的化学势的差别生产铁原子的驱动力从一个阶段移居到另外的阶段。另外,接口迁居罐头改变奥氏体部分;作为结果,在划分温度的奥氏体部分可能在通过接口移植熄灭温度比那高,但是这现象不能被用户终端设备模型解释。 | Ning ZHONG Xiaodong WANG Yonghua RONG Li WANG | 2006 | Journal of Materials Science & Technology2006，22，6： | 19 |
| 10 | Moisture distribution in sludges based on different testing methods显示文摘Moisture distributions in municipal sewage sludge, printing and dyeing sludge and paper mill sludge were experimentally studied based on four different methods, i.e., drying test, thermogravimetric-differential thermal analysis (TG-DTA) test, thermogravimetric-differential scanning calorimetry (TG-DSC) test and water activity test. The results indicated that the moistures in the mechanically dewatered sludges were interstitial water, surface water and bound water. The interstitial water accounted for more than 50% wet basis (wb) of the total moisture content. The bond strength of sludge moisture increased with decreasing moisture content, especially when the moisture content was lower than 50% wb. Furthermore, the comparison among the four different testing methods was presented. The drying test was advantaged by its ability to quantify free water, interstitial water, surface water and bound water; while TG-DSC test, TG-DTA test and water activity test were capable of determining the bond strength of moisture in sludge. It was found that the results from TG-DSC and TG-DTA test are more persuasive than water activity test. | Wenyi Deng Xiaodong Li Jianhua Yan Fei Wang Yong Chi Kefa Cen | 2011 | Journal of Environmental Sciences2011，23，5： | 19 |
| 11 | Entransy-dissipation-based thermal resistance analysis of heat exchanger networks显示文摘Heat exchanger network optimization has an important role in high-efficiency energy utilization and energy conservation. The thermal resistance of a heat exchanger network is defined based on its entransy dissipation. In two-stream heat exchanger networks, only heat exchanges between hot and cold fluids are considered. Thermal resistance analysis indicates that the maximum heat transfer rate between two fluids corresponds to the minimum entransy-dissipation-based thermal resistance; i.e. the minimum thermal resistance principle can be exploited in optimizing heat exchanger networks. | QIAN XiaoDong LI Zhen LI ZhiXin | 2011 | Chinese Science Bulletin2011，56，31： | 19 |
| 12 | From concept to reality-A review to the primary test stand and its preliminary application in high energy density physics显示文摘Pulsed power technology,whereas the electrical energy stored in a relative long period is released in much shorter timescale,is an efficient method to create high energy density physics(HEDP)conditions in laboratory.Around the beginning of this century,China Academy of Engineering Physics(CAEP)began to build some experimental facilities for HEDP investigations,among which the Primary Test Stand(PTS),a multi-module pulsed power facility with a nominal current of 10 MA and a current rising time~90 ns,is an important achievement on the roadmap of the electro-magnetically driven inertial confinement fusion(ICF)researches.PTS is the first pulsed power facility beyond 10 TW in China.Therefore,all the technologies have to be demonstrated,and all the engineering issues have to be overcome.In this article,the research outline,key technologies and the preliminary HEDP experiments are reviewed.Prospects on HEDP research on PTS and pulsed power development for the next step are also discussed. | Jianjun Deng Weiping Xie Shuping Feng Meng Wang Hongtao Li Shengyi Song Minghe Xia Ji Ce An He Qing Tian Yuanchao Gu Yongchao Guan Bin Wei Xianbin Huang Xiaodong Ren Jiakun Dan Jing Li Shaotong Zhou Hongchun Cai Siqun Zhang Kunlun Wang Qiang Xu Yujuan Wang Zhaohui Zhang Guilin Wang Shuai Guo Yi He Yiwei Zhou Zhanji Zhang Libing Yang Wenkang Zou | 2016 | Matter and Radiation at Extremes2016，1，1： | 19 |
| 13 | A comparative study between Embosphere~ and conventional transcatheter arterial chemoembolization for treatment of unresectable liver metastasis from GIST显示文摘Objective:Transcatheter arterial chemoembolization(TACE) is a standard treatment for hepatocellular carcinoma(HCC) and/or some unresectable liver metastasis tumors.Hypervascular liver metastatic lesions such as metastasis from gastrointestinal stromal tumor(GIST) are an indication for transcatheter arterial embolization(TAE).The purpose of this study was to evaluate the efficacy and safety of Embosphere~-TAE(Embo-TAE) in comparison with conventional TACE(cTACE) for the treatment of liver metastasis from GIST.Methods:A total of 45 patients who underwent TACE between Aug 2008 and Feb 2013 were enrolled.Patients with GIST who underwent TAE with Embosphere~(n=19) were compared with controls who received cTACE(n=26).The primary end points were treatment response and treatment-related adverse events.The secondary end points were progression-free survival(PFS) and overall survival(OS).Results:The treatment response of Embo-TAE group was significantly higher than that of the cTACE group(P<0.001).The PFS was significantly better in the Embosphere~-group than in the cTACE group(56.6 and 42.1 weeks,respectively;P=0.003).However,there was no statistically significant difference in liver toxicity between the two groups(P>0.05).The median OS in the Embo-TAE group was longer than that in the cTACE group(74.0 weeks,95% CI:68.2-79.8 vs.61.7 weeks,95% CI:56.2-67.2 weeks)(unadjusted P=0.045).The use of Embo-TAE significantly reduced the risk of death in patients with GIST with liver metastases according to the Cox proportional hazards regression model [hazard ratio(HR):0.149;95% CI:0.064-0.475].Conclusions:TAE with Embosphere~ showed better treatment response and delayed tumor progression compared with cTACE.There was no significant difference in treatment-related hepatic toxicities.EmboTAE thus appears to be a feasible and promising approach in the treatment of liver metastasis from GIST. | Guang Cao Xu Zhu Jian Li Lin Shen Renjie Yang Hui Chen Xiaodong Wang Song Gao Haifeng Xu Linzhong Zhu Peng Liu Jianhai Guo | 2014 | Chinese Journal of Cancer Research2014，26，1： | 18 |
| 14 | Emission characteristics of dioxins,furans and polycyclic aromatic hydrocarbons during fluidized-bed combustion of sewage sludge显示文摘Pre-dried sewage sludge with high sulfur content was combusted in an electrically heated lab-scale fluidized-bed incinerator. The emission characteristics of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polycyclic aromatic hydrocarbons (PAHs) were studied. Coal and calcium oxide (CaO) were added during the sewage sludge combustion tests to optimize combustion conditions and control SO2 emission. The results indicated that the flue gases emitted during mono-combustion of sewage sludge were characterized by relatively high concentrations of SO2, NOx and organic pollutants, due to the high sulfur, nitrogen, and volatile matter content of sewage sludge. The total 16 USEPA priority PAHs and 2,3,7,8-substituted PCDD/Fs produced from sewage sludge combustion were found to be 106.14 μg/m3 and 8955.93 pg/m3 in the flue gas, respectively. In the case of co- combustion with coal (msludge/mcoal = 1:1), the 16 PAHs and 2,3,7,8-substituted PCDD/Fs concentrations were markedly lower than those found during mono-combustion of sewage sludge. During co-combustion, a suppressant effect of CaO on PCDD/Fs formation was observed. | DENG Wenyi, YAN Jianhua, LI Xiaodong, WANG Fei, CHI Yong, LU ShengyongState Key Laboratory of Clean Energy Utilization, Institute for Thermal Power Engineering, Zhejiang University, Hangzhou 310027, China. | 2009 | Journal of Environmental Sciences2009，21，12： | 17 |
| 15 | Prostate cancer identification: quantitative analysis of T2-weighted MR images based on a back propagation artificial neural network model显示文摘Computer-aided diagnosis(CAD) systems have been proposed to assist radiologists in making diagnostic decisions by providing helpful information. As one of the most important sequences in prostate magnetic resonance imaging(MRI), image features from T2-weighted images(T2WI) were extracted and evaluated for the diagnostic performances by using CAD. We extracted 12 quantitative image features from prostate T2-weighted MR images. The importance of each feature in cancer identification was compared in the peripheral zone(PZ) and central gland(CG), respectively. The performance of the computer-aided diagnosis system supported by an artificial neural network was tested. With computer-aided analysis of T2-weighted images, many characteristic features with different diagnostic capabilities can be extracted. We discovered most of the features(10/12) had significant difference(P<0.01) between PCa and non-PCa in the PZ, while only five features(sum average, minimum value, standard deviation, 10 th percentile, and entropy) had significant difference in CG. CAD prediction by features from T2 w images can reach high accuracy and specificity while maintaining acceptable sensitivity. The outcome is convictive and helpful in medical diagnosis. | ZHAO Kai WANG ChengYan HU Juan YANG XueDong WANG He LI FeiYu ZHANG XiaoDong ZHANG Jue WANG XiaoYing | 2015 | Science China(Life Sciences)2015，58，7： | 16 |
| 16 | Slope spectrum critical area and its spatial variation in the Loess Plateau of China显示文摘斜坡光谱被证明了是在在中国黄土地面的学习揭示 geomorphological 特征的重要方法论。在导出斜坡系列的批评区域的决心是一项不可缺少的任务。与学习区域的尺寸的增加一起,导出的系列越来越同样地正在变得,以便他们的差别能被忽略赞成一个标准。随后,测试尺寸被定义为斜坡光谱批评区域(SSCA ) 。SSCA 是斜坡光谱计算的基础不仅而且到某程度,黄土地势的 geomorphological 开发的思考。高分辨率 DEM 在提取斜坡光谱是重要的。有在北 Shaanxi 省的黄土高原的不同地形区域的一套 48 DEM 为实验被选择。SSCA 的空间分发与一个 geo 统计的分析方法被调查,导致从 6.18 km 2到 35.1 km 2 的价值。主要试验性的结果证明 SSCA 的空间分发与土壤侵蚀紧张的空间分发被相关,到反映地面复杂性的某个程度。斜坡光谱的批评区域从北方介绍 weak-strong-weak 的一个空间变化趋势给南方。四个地面参数,溪谷密度,斜坡偏斜度,地面驱动力(T d ) 和斜坡(求救) 的斜坡,被选择为指示物。在那里存在在 SSCA 和溪谷密度之间的一种好指数的功能关系,地面驱动力(T d ) 和在 SSCA 和斜坡偏斜度之间的一种对数函数关系。斜坡偏斜度增加,和溪谷密度,地面驱动力和求救与增加 SSCA 减少。SSCA 能作为一个区别因素被利用识别黄土地形,因为 SSCA 和黄土地形的进化的空间分布是关联词。从台地跟随黄土地形的进化到溪谷多山的区域,这也证明 SSCA 能代表本地地形的发展度。黄土高原的批评稳定的区域代表黄土地形的开发的度。它的主要意义是稳定的区域的感觉能被用来决定最小的地理单位。 | TANG Guoan SONG Xiaodong LI Fayuan ZHANG Yong XION-GLiyang | 2015 | Journal of Geographical Sciences2015，25，12： | 16 |
| 17 | Integrating TM and Ancillary Geographical Data with Classification Trees for Land Cover Classification of Marsh Area显示文摘The main objective of this research is to determine the capacity of land cover classification combining spec- tral and textural features of Landsat TM imagery with ancillary geographical data in wetlands of the Sanjiang Plain, Heilongjiang Province, China. Semi-variograms and Z-test value were calculated to assess the separability of grey-level co-occurrence texture measures to maximize the difference between land cover types. The degree of spatial autocorrelation showed that window sizes of 3×3 pixels and 11×11 pixels were most appropriate for Landsat TM im- age texture calculations. The texture analysis showed that co-occurrence entropy, dissimilarity, and variance texture measures, derived from the Landsat TM spectrum bands and vegetation indices provided the most significant statistical differentiation between land cover types. Subsequently, a Classification and Regression Tree (CART) algorithm was applied to three different combinations of predictors: 1) TM imagery alone (TM-only); 2) TM imagery plus image texture (TM+TXT model); and 3) all predictors including TM imagery, image texture and additional ancillary GIS in- formation (TM+TXT+GIS model). Compared with traditional Maximum Likelihood Classification (MLC) supervised classification, three classification trees predictive models reduced the overall error rate significantly. Image texture measures and ancillary geographical variables depressed the speckle noise effectively and reduced classification error rate of marsh obviously. For classification trees model making use of all available predictors, omission error rate was 12.90% and commission error rate was 10.99% for marsh. The developed method is portable, relatively easy to im- plement and should be applicable in other settings and over larger extents. | NA Xiaodong ZHANG Shuqing ZHANG Huaiqing LI Xiaofeng YU Huan LIU Chunyue | 2009 | Chinese Geographical Science2009，19，2： | 14 |
| 18 | Effect of catgut implantation at acupoints on GABA_B and mGluR1 expressions in brain stem of rats with spasticity after stroke显示文摘OBJECTIVE: To investigate the effect of catgut implantation at acupoints on the expressions of γ-amino butyric acid B receptor(GABAB ) and metabotropic glutamate receptor 1(mGluR1) in the brain stem of rats with spasticity after stroke.METHODS: In total, 60 male Sprague-Dawley rats were randomly divided into three groups: a sham group(n=10), a model group(n=25) and a treatment group(n=25). The rats in both the model group and the treatment group were subjected to middle cerebral artery occlusion to establish a model of focal cerebral ischemia. Rats with limb-spasm met the inclusion criteria. Only the left carotid artery was isolated in sham group rats. Three days after modeling, the treatment group was subjected to catgut implantation at Dazhui(GV 14), Guanyuan(CV 4), and Zhongwan(CV 12). Neurological deficit symptoms were assessed with the Zea-Longa neurological deficit score. The Modified Ashworth Scale(MAS), and isolated muscle tone were used to evaluate spasticity before and after treatment. Immunohistochemistry was applied to determine the expression of GABAB and mGluR1 in the rat brain stem after treatment.RESULTS: After treatment, neural impairment symptoms had significantly improved in the treatment group when compared to the model group(P<0.05). Both MAS and isolated muscle tone in the treatment group were significantly decreased when compared with the model group(P<0.05),and were also lower than before treatment. GABAB expression was significantly higher and mGluR1 was lower in the treatment group when compared with the model group(P<0.01 and P<0.05, respectively).CONCLUSION: Catgut implantation at Dazhui(GV 14), Guanyuan(CV 4), and Zhongwan(CV 12), can relieve limb spasticity by increasing the expression of GABAB and reducing the expression of mGluR1 in the brain stem of rats after stroke. | Chengmei Liu Ruiqing Li Xiaolei Song Xiaodong Feng | 2014 | Journal of Traditional Chinese Medicine2014，34，5： | 14 |
| 19 | Rapid aerobic granulation in an SBR treating piggery wastewater by seeding sludge from a municipal WWTP显示文摘Aerobic sludge granulation was rapidly obtained in the erlenmeyer bottle and sequencing batch reactor(SBR) using piggery wastewater.Aerobic granulation occurred on day 3 and granules with mean diameter of 0.2 mm and SVI_(30) of 20.3 mL/g formed in SBR on day 18.High concentrations of Ca and Fe in the raw piggery wastewater and operating mode accelerated aerobic granulation,even though the seed sludge was from a municipal wastewater treatment plant(WWTP).Alpha diversity analysis revealed Operational Taxonomic Units,Shannon,ACE and Chao 1 indexes in aerobic granules were 2013,5.51,4665.5 and 3734.5,which were obviously lower compared to seed sludge.The percentages of major microbial communities,such as Protect)acteria,Bacteroidetes and Firmicutes were obviously higher in aerobic granules than seed sludge.Chlorqflexi,Planctomycetes,Actinobactena,TM7 and Aridobacteria showed much higher abundances in the inoculum.The main reasons might be the characteristics of raw piggery wastewater and granule structure. | Jun Liu Jun Li Xiaodong Wang Qi Zhang Helen Littleton | 2017 | Journal of Environmental Sciences2017，29，1： | 14 |
| 20 | Effect of barium sulfate modification on the SO2 tolerance of V2O5/TiO2 catalyst for NH3-SCR reaction显示文摘Sulfur poisoning of V_2O_5/BaSO_4–TiO_2(VBT),V_2O_5/WO_3–TiO_2(VWT) and V_2O_5/BaSO_4–WO_3–TiO_2(VBWT) catalysts was performed in wet air at 350℃ for 3 hr,and activities for the selective catalytic reduction of NO_x with NH_3 were evaluated for 200–500℃.The VBT catalyst showed higher NO_x conversions after sulfur poisoning than the other two catalysts.The introduction of barium sulfate contributed to strong acid sites for the as-received catalyst,and eliminated the redox cycle of active vanadium oxide to some extent,which resulted in a certain loss of activity.Readily decomposable sulfate species formed on VBT-S instead of inactive sulfates on VWT-S.These decomposable sulfates increased the number of strong acid sites significantly.Some sulfate species escaped during catalyst preparation and barium sulfate was reproduced during sulfur poisoning,which protects vanadia from sulfur oxide attachment to a great extent.Consequently,the VBT catalyst exhibited the best resistance to sulfur poisoning. | Tengfei Xu Xiaodong Wu Xuesong Liu Li Cao Qiwei Lin Duan Weng | 2017 | Journal of Environmental Sciences2017，29，7： | 14 |
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