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| 1 | An insoluble polysaccharide from the sclerotium of Poria cocos improves hyperglycemia, hyperlipidemia and hepatic steatosis in ob/ob mice via modulation of gut microbiota显示文摘Metabolic syndrome characterized by obesity, hyperglycemia and liver steatosis is becoming prevalent all over the world. Herein, a water insoluble polysaccharide(WIP) was isolated and identified from the sclerotium of Poria cocos, a widely used Traditional Chinese Medicine. WIP was confirmed to be a(1-3)-β-D-glucan with an average Mw of 4.486 × 10~6 Da by NMR and SEC-RI-MALLS analyses. Furthermore, oral treatment with WIP from P. cocos significantly improved glucose and lipid metabolism and alleviated hepatic steatosis in ob/ob mice. 16 S DNA sequencing analysis of cecum content from WIP-treated mice indicated the increase of butyrate-producing bacteria Lachnospiracea, Clostridium. It was also observed that WIP treatment elevated the level of butyrate in gut, improved the gut mucosal integrity and activated the intestinal PPAR-γ pathway. Fecal transplantation experiments definitely confirmed the causative role of gut microbiota in mediating the benefits of WIP. It is the first report that the water insoluble polysaccharide from the sclerotium of P. cocos modulates gut microbiota to improve hyperglycemia and hyperlipidemia. Thereby, WIP from P. cocos, as a prebiotic, has the potential for the prevention or cure of metabolic diseases and may elucidate new mechanism for the efficacies of this traditional herbal medicine on the regulation of lipid and glucose metabolism. | SUN Shan-Shan WANG Kai MA Ke BAO Li LIU Hong-Wei | 2019 | Chinese Journal of Natural Medicines2019，17，1： | 60 |
| 2 | New type of potassium deposit: Modal analysis and preparation of potassium carbonate显示文摘A kind of dolomitic mudstone newly found in North China has high amounts of K2O up to 10wB% in average, and potassium reserve is at superior scale. Mineral assemblage of the potassium ore indicates a specific and complicated geological environment under which the po-tassium deposit formed. Modal analysis of the potassium host rock shows that the principal min-erals in the ore include microcline, dolomite, and clay minerals such as illite, illite/smectite mixed layer, and kaolinite, attributable to a new type of insoluble potassium deposits in ore genesis. The experiments in this research demonstrated that with sodium carbonate as flux agent, the potas-sium ore could be decomposed with a proportion as high as 99.4% by calcinations at moderate temperature for no more than 1.5―2.0 h; more than 70% of K2O in the calcined materials were leached into the liquor, and by acidification reaction of the filter liquor, a large amount of impuri-ties such as Fe3+, Ti4+, Mn2+, Mg2+, and Ca2+ were removed with precipitation of alumino-silicious colloid residue, which makes it possible to prepare potassium carbonate of electronic grade from the filter liquor, whereas the alumino-silicious residue could be utilized to make mineral polymer, a new type of inorganic construction structural materials. The current research shows that in-dustrial exploitation and comprehensive utilization of this new type of insoluble potassium re-source are feasible both in economic benefits and environmental kindness with the fairly clean production process as sketched in this paper. | MA Hongwen1, FENG Wuwei1, MIAO Shiding1, WANG Yingbin1 & TIAN Shuxin2 1. National Laboratory of Mineral Materials, China University of Geosciences, Beijing 100083, China 2.Tianjin Bureau of Geological Survey, Tianjin 300191, China | 2005 | Science China Earth Sciences2005，48，11： | 16 |
| 3 | Alfalfa-containing diets alter luminal microbiota structure and short chain fatty acid sensing in the caecal mucosa of pigs显示文摘Background: Pork produced by outdoor-reared pigs raised mostly on alfalfa pastures attracts increasing population of consumer from most of the world. In China, pigs were raised with alfalfa-containing diets to seek for good quality pork.However, the influence of dietary alfalfa involving high level of insoluble dietary fiber(IDF) on pig intestinal luminal microbiota composition remains unclear. The objective of this study was to investigate the effects of alfalfa on luminal microbiota and short chain fatty acids(SCFA) production, and gene expressions involved in SCFA sensing, transporting and absorbing in pig caecal mucosa.Results: Twenty-four growing pigs were randomly allotted to four diets containing 0%, 5%, 10% and 15% alfalfa meal for a 28-d experiment. Ingestion of alfalfa meal-contained diets significantly increased the ratio of body weight gain to feed consumption. Illumina MiS eq sequencing of the V3 region of the 16 S r RNA genes showed that alfalfa-containing diet significantly decreased the relative abundance of genera Turicibacter, Acidiphilium, Paracoccus, Propionibacterium,Corynebacterium, Pseudomonas, Acinetobacter, and Staphylococcus, and increased the relative abundance of genera Lachnospira, Marvinbryantia, and Desulfovibrio in the caecal digesta. Butyrate concentration was significantly increased in the hindgut by the supplementation of alfalfa meal in diets. The m RNA gene expressions of FFAR3, SMCT1, MCT1,PYY, and GCG were significantly increased in the caecal mucosa of pigs fed alfalfa meal.Conclusions: Our results suggested that alfalfa-containing diet has exerted significant impacts on caecal microbiota composition, butyrate concentration and significantly upregulated m RNA expression of host caecal mucosal genes involved in SCFA sensing and absorption as well as regulation of satiety. | Jiawei Wang Chunfu Qin Ting He Kai Qiu Wenjuan Sun Xin Zhang Ning Jiao Weiyun Zhu Jingdong Yin | 2018 | Journal of Animal Science and Biotechnology2018，9，2： | 12 |
| 4 | A chemical index of weather-ing without effect of wind sorting: Fe/Mg ratios in the acid-insoluble phases of loess deposits显示文摘Chemical analysis of acid-insoluble fractions in loess and paleosols shows that concentrations of Fe and Mg were under control of wind sorting and post-depositional weathering-pedogenesis. The former caused Fe and Mg concentrated in the finer grain-size fractions, displaying synchronous variations, while the latter made Fe and Mg separated, leading to Fe retained in the weathered section and Mg leached out. Therefore, Fe/Mg ratios in the acid insoluble fraction of loess and paleosols can eliminate the effect of wind sorting and serve as an excellent proxy record on intensity of weathering-pedogenesis. Based on calculation, leaching percentage of Mg in the paleosol S1 from the Luochuan, Xifeng and Huanxian sections is 15%, 11% and 2%, respectively, and on average 9% for the paleosols S2—S14 from the Luochuan section, with the highest value amounting to 22% in S5-1, suggesting the strongest weathering-pedogenesis. | Liu, LW Chen, J Wang, HT Chen, Y | 2001 | Chinese Science Bulletin2001，46，16： | 5 |
| 5 | HYPOCRELLIN A—A NEW DRUG FOR PHOTOCHEMOTHERAPY显示文摘We have isolated a photodynamic pigment from the natural sources of Hypocrella bambusae (B. et Br.) sacc. (Hypocreaceae, Ascomycetes). The red pigment is soluble in most of the common organic solvents. It is readily soluble in both chloroform and acetone, somewhat soluble in hot light petroleum, but insoluble in water. When the acetone solution of this compound was exposed to light, it would combine with two oxygen atoms and turn into a yellowish-red compound like cladochrome. The red pigment was recrystallized from acetone (m. p. 209—210℃). Both elemental analysis (C 65.81%, | 万象义 陈远腾 | 1981 | Chinese Science Bulletin1981，26，11： | 3 |
| 6 | phytoestrogens/insoluble fibers and colonic estrogen receptor β: randomized, double-blind, placebo-controlled study显示文摘AIM:To assess the safety and effect of the supplementation of a patented blend of dietary phytoestrogens and insoluble fibers on estrogen receptor (ER)-β and biological parameters in sporadic colonic adenomas. METHODS:A randomized, double-blind placebo-controlled trial was performed. Patients scheduled to undergo surveillance colonoscopy for previous sporadic colonic adenomas were identified, and 60 eligible patients were randomized to placebo or active dietary intervention (ADI) twice a day, for 60 d before surveillance colonoscopy. ADI was a mixture of 175 mg milk thistle extract, 20 mg secoisolariciresinol and 750 mg oat fiber extract. ER-β and ER-α expression, apoptosis and proliferation (Ki-67 LI) were assessed in colon samples. RESULTS:No adverse event related to ADI was recorded. ADI administration showed a significant increases in ER-β protein (0.822 ± 0.08 vs 0.768 ± 0.10, P = 0.04) and a general trend to an increase in ER-β LI (39.222 ± 2.69vs 37.708 ± 5.31,P = 0.06), ER-β/ER-α LI ratio (6.564 ± 10.04 vs 2.437 ± 1.53, P = 0.06), terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (35.592 ± 14.97 vs 31.541 ± 11.54, P = 0.07) and Ki-67 (53.923 ± 20.91 vs 44.833 ± 10.38, P = 0.07) approximating statistical significance. A significant increase of ER-β protein (0.805 ± 0.13 vs 0.773 ± 0.13,P = 0.04), mRNA (2.278 ± 1.19vs 1.105 ± 1.07, P < 0.02) and LI (47.533 ± 15.47 vs 34.875 ± 16.67,P < 0.05) and a decrease of ER-α protein (0.423 ± 0.06vs 0.532 ± 0.11,P < 0.02) as well as a trend to increase of ER-β/ER-α protein in ADI vs placebo group were observed in patients without polyps (1.734 ± 0.20 vs 1.571 ± 0.42, P = 0.07). CONCLUSION:The role of ER-β on the control of apoptosis, and its amenability to dietary intervention, are supported in our study. | Mariabeatrice Principi Alfredo Di Leo Maria Pricci Maria Principia Scavo Raffaella Guido Sabina Tanzi Domenico Piscitelli Antonio Pisani Enzo Ierardi Maria Cristina Comelli Michele Barone | 2013 | World Journal of Gastroenterology2013，19，27： | 3 |
| 7 | KINETICS OF THE DECOMPOSlTION OF SCHEELITE CONCENTRATE BY LEACHEX PROCESS显示文摘The new method named as LEACHEX process which combines leaching of minearl and extraction of metalfrom leaching liquor is used to proccss scheelite concentrate.Elimination of solid film consisting of tungstic acidand the controlling step of chemical reaction are illustrated and an empirical kinetic equation is proposed basedon unreacted-shrinking-core model.90 percent decomposition of scheelite can be attained in 1800 seconds. | 高浩其 苏元复 | 1991 | Chinese Journal of Chemical Engineering1991，，1： | 1 |
| 8 | Selective Adsorption and Electrocatalysis of Polysulfides through Hexatomic Nickel Clusters Embedded in N-Doped Graphene toward High-Performance Li-S Batteries显示文摘The shuttle effect hinders the practical application of lithium-sulfur(Li-S)batteries due to the poor affinity between a substrate and Li polysulfides(LiPSs)and the sluggish transition of soluble LiPSs to insoluble Li2S or elemental S.Here,we report that Ni hexatomic clusters embedded in a nitrogen-doped three-dimensional(3D)graphene framework(Ni-N/G)possess stronger interaction with soluble polysulfides than that with insoluble polysulfides.The synthetic electrocatalyst deployed in the sulfur cathode plays a multifunctional role:(i)selectively adsorbing the polysulfides dissolved in the electrolyte,(ii)expediting the sluggish liquid-solid phase transformations at the active sites as electrocatalysts,and(iii)accelerating the kinetics of the electrochemical reaction of multielectron sulfur,thereby inhibiting the dissolution of LiPSs.The constructed S@Ni-N/G cathode delivers an areal capacity of 9.43mAhcm^(-2) at 0.1 C at S loading of 6.8 mg cm^(-2),and it exhibits a gravimetric capacity of 1104mAhg^(-1) with a capacity fading rate of 0.045%per cycle over 50 cycles at 0.2 C at S loading of 2.0 mg cm^(-2).This work opens a rational approach to achieve the selective adsorption and expediting of polysulfide transition for the performance enhancement of Li-S batteries. | Jiapeng Ji Ying Sha Zeheng Li Xuehui Gao Teng Zhang Shiyu Zhou Tong Qiu Shaodong Zhou Liang Zhang Min Ling Yanglong Hou Chengdu Liang | 2020 | Research2020，，1： | 1 |
| 9 | SYNTHESIS AND CHARACTERISTIC OF POLYSILANES CONTAINING Si-H BOND显示文摘Three kinds of polysilanes containing Si-H bond,■■ CH3SiCH3■x■CH3SiH■y■n and■PhSiPh■π■CH3SiH■y■CH3SiCH3■, have been synthesized. The structures of these copolymers were investigated by IR, 1H-NMR and 13C-NMR and their molecular weights were measured. | Ying Kui LI~*, Zhao Hui CHEN Department of Materials Science and Applied Chemistry,Changsha Institute of Tecbnology, Changsha 410003, China. | 1992 | Chinese Chemical Letters1992，3，10： | 1 |
| 10 | MECHANISM OF LIGHT RESISTANCE AND HEAT AGEING RESISTANCE FOR RED MUD——THE PVC COMPOSITE PLASTICS显示文摘Red mud——polyvinylchloride composite plastics is manufactured from an insoluble residue (generally called red mud) after extraction of alumina from bauxite in the Bayer process, polyvinylchloride and a small amount of auxiliary material through mixing. It is a kind of low-price composite plastics with excellent properties of | 田元江 李惠文 | 1984 | Chinese Science Bulletin1984，29，6： | 1 |
| 11 | STATISTICAL ANALYSIS OF COPRECIPITATE IONS AND CARRIERS IN ANALYTICAL CHEMISTRY显示文摘The method for coprecipitation separation and enrichment is a method often used in analytical chemistry, because it does not require special reagents and equipments. Up to now it is still one of the easy and efficient ways in every respect for | 胡之德 | 1980 | Chinese Science Bulletin1980，25，4： | 1 |
| 12 | EVOLUTION DIAGRAM OF KEROGEN STRUCTURE IN THE PROCESS OF HYDROCARBON FORMATION显示文摘It has been established that kerogen, the insoluble organic material in source rocks, is the most principal source matrix for hydrocarbon generation. With the increase of burial depth, there occurs hydrocarbon-forming degradation in kerogen due to thermal effects, while kerogen itself becomes even more polycondensed | 黄第藩 李晋超 王会祥 | 1988 | Chinese Science Bulletin1988，33，12： | 0 |
| 13 | SYNTHESIS AND CHARACTERIZATION OF POLYBENZOTHIAZOLAMIDES显示文摘Aromatic polybenzothiazolamides were prepared by low temperature solution method by condensing the 2, 2’-diarnino-6, 6’-bibenzothiazole with four different acid chlorides in quantitative yield. These polymers were characterized by IR and NMR. Viscosities of these polyamides range from 0.42 to 1 dl/gm. All these polymers were stable upto 300℃in air. | S. PADMA V. MAHADEVAN M. SRINIVASAN | 1989 | Chinese Journal of Polymer Science1989，7，3： | 0 |
| 14 | RELATIONSHIP BETWEEN ACTIVITIES OF CYTOCHROME P-450 MONOOXYGENASES IN HUMAN PLACENTAL MICROSOMES AND BINDING OF BENZO(A)PYRENE METABOLITES TO CALF THYMUS DNA.显示文摘Benzo(a)pyrene metabolism in human placental microsomes fromsmokers was studied.Benzo(a)pyrene metabolites were separatedusing high pressure liquid chromatographic technique. Reactionof benzo(a)pyrene with microsomal fraction of placenta fromindividuals who smoke cigarette during pregnency yields 7。 | Ke Won Kang | 1991 | 癌变.畸变.突变1991，3，S1： | 0 |
| 15 | Experimental investigation on the effect of surface characterization of electrodes on the gas bubble dynamics in electrolyte flow and performance of FLA batteries by using PIV显示文摘In the flooded lead_acid batteries(FLAB),gas bubbles are initially formed on the surface of the electrodes,which are produced by electrochemical reactions,and then released into the electrolyte.In the present investigation,the effect of surface characterization of electrodes of FLAB on the gas bubble dynamic parameters in the electrolyte flow at different charging/discharging rates(C-rates)are studied utilizing particle image velocimetry(PIV)method.The results show that the capacity of FLAB have a linear behavior due to changes in each of the two parameters of the surface characterization of electrodes and the Crate.At all State of charges(SOCs)of FLAB cells in different tests,increasing average roughness(Ra)and average wavelength of the roughness(λa)in the electrode surfaces,results in an increase in average bubble diameter and bubble rising velocity.Nevertheless,a sharp decrease in the void fraction of bubbles within the electrolyte was observed due to the increment inλa and Ra.Also,the effect of the rising movement of gas bubbles within the electrolyte on the average electrolyte velocity pattern in the gap between the electrodes by changing the surface characterization of electrodes are investigated in detail. | Saeed Nahidi Iraj Jafari Gavzan Seyfolah Saedodin Mahmoud Salari | 2021 | Chinese Journal of Chemical Engineering2021，34，5： | 0 |
| 16 | REGULARITY OF THE SOLUBILITIES OF HYDROXIDES显示文摘For the solubilities of inorganic salts,theoretical expressions have been proposed by several workers, and those suggested for the hydroxides by Clifford and Shing Shingchuan are of practical significance.Starting from the molecular polarizabilities of insoluble salts, Clifford presented an empirical formula giving the relation between the solubility product constant and electronegativity for in- | 杨进元 | 1966 | Chinese Science Bulletin1966，24，2： | 0 |
| 17 | THE STUDYOF SYNTHESIS AND CHARACTERISTICS OF POLYPHENYLACETYLENE USING WOBr_4AS CATALYST显示文摘A new kind of catalyst WOBr4,which can be used in the polymerization ofphenylacetylene(PhA),has been synthesized.The obtained polyphenyl(?)cetylene(PPhA)using WOBr4 as catalyst is soluble、fusible、with brown-red colour and has 1831(Mn).The analysis of the stucture of PPhA shows that the polymer has cis-transoidalstructure,therefore,the reaction mechanism is via complex catalysis. | Yin Kui LI Zhao Hui CHEN Department of Materials Science and Applied Chemistry,Changsha Institute of Technology,Changsha 410003 | 1992 | Chinese Chemical Letters1992，3，1： | 0 |
| 18 | THE SYNTHESIS AND STRUCTURAL INVESTIGATION OF SOME BINUCLEAR ORGANOMETALLIC COMPLEXES WITH IRON-TORARE EARTH BOND显示文摘The heteronuclear organometallic complexes with metal-to-metal bond may act as some model compounds in the investigation of catalytic mechanisms or may potentially be catalytically active, and therefore they attract much attention to their research. There were not very many reports about organometallic complexes with metal-to-rare | 王序昆 周晓欣 张经坤 夏元复 刘荣川 王述新 | 1985 | Chinese Science Bulletin1985，30，3： | 0 |
| 19 | N-ALKYLPHENOTHIAZINE RADICAL CATIONS GENERATED IN THE CAVITY OF β-CYCLODEXTRINS IN A(?)UEOUS SOLUTION显示文摘Phenothiazine and i+s derivatives were oxidized by l2 and 2,2,6,6-tetrametbyl-4-acetyloxypiperidine oxoammonium hexachloroantimonate to the corresponding radical cationsin the cavity of β-cyclodextrins in aqueous solution.The mechanism of electron transferbetween substrates and oxidants is discussed in terms of association of β-CDs. | Qing Xiang GUO Ping HUAN Bo LIU You Cheng LIU Depar’ment of Chemistry,Lanzhou University,Lanzhou 730000 | 1992 | Chinese Chemical Letters1992，3，1： | 0 |
| 20 | STUDIES ON THE SITE OF DEGRADATION OF ORGANOPHOSPHATE INSECTICIDES IN MOSQUITOES显示文摘Malsumura and Hogendijk (1964) found that there was a difference in phosphatase activity between organophosphorus (OP)-resistant and sensitive (SEN) strains of houseflies. Welling et al. (1971) found that the resistant strain of houseflies could degrade paraoxon to produce biethyl phosphonic acid. Oppenoorth and Voerman (1975) found that in OP-resistant strain of Muzus persicae, phosphatase could degrade the malathion to produce bimethyl phosphonic acid. From the above studies, | 吴敦肃 | 1988 | Chinese Science Bulletin1988，33，9： | 0 |
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