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| 1 | 转录组平台技术及其在代谢工程中的应用显示文摘组学技术在系统水平上对细胞代谢进行全面的分析,极大地促进了代谢工程的发展和应用。全基因组水平的转录分析可以使研究者更加精确地评估细胞表型,加深对细胞代谢的理解。而且转录组分析也有助于研究者鉴定菌种改良的目标基因,加速对微生物细胞工厂的合理设计及构建。文中介绍了3种主要转录组平台技术的原理,并总结了转录组学在代谢工程领域中应用的最新进展和未来发展趋势。 | 史硕博 陈涛 赵学明 | 2010 | 生物工程学报2010,26,9: | 23 |
| 2 | Genome-scale profiling of circulating cell-free DNA signatures for early detection of hepatocellular carcinoma in cirrhotic patients显示文摘Dear Editor,Hepatocellular carcinoma(HCC)is the second most deadly cancer worldwide.1 Cirrhosis of different causes predisposes patients to HCC,increasing the annual HCC incidence by 2%–4%.1 The development of cirrhosis facilitates a series of genetic or epigenetic changes,resulting in the formation of dysplastic nodules,a premalignant stage in HCC.1 HCC diagnosis at an early stage contributes to an improved prognosis with the possibility of curative treatment.Due to the low accuracy of current diagnostic methods,it is urgently needed to explore new non-invasive strategies for early HCC diagnosis in cirrhotic patients. | Lei Chen Ghassan K.Abou-Alfa Bo Zheng Jing-Feng Liu Jian Bai Lu-Tao Du Yun-Song Qian Rong Fan Xiao-Long Liu Lin Wu Jin-Lin Hou Hong-Yang Wang The PreCar Team | 2021 | Cell Research2021,31,5: | 20 |
| 3 | Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma显示文摘Nasopharyngeal carcinoma(NPC)is an aggressive malignancy with extremely skewed ethnic and geographic distributions.Increasing evidence indicates that targeting the tumor microenvironment(TME)represents a promising therapeutic approach in NPC,highlighting an urgent need to deepen the understanding of the complex NPC TME.Here,we generated single-cell transcriptome profiles for 7581 malignant cells and 40,285 immune cells from fifteen primary NPC tumors and one normal sample.We revealed malignant signatures capturing intratumoral transcriptional heterogeneity and predicting aggressiveness of malignant cells.Diverse immune cell subtypes were identified,including novel subtypes such as CLEC9A^+dendritic cells(DCs).We further revealed transcriptional regulators underlying immune cell diversity,and cell–cell interaction analyses highlighted promising immunotherapeutic targets in NPC.Moreover,we established the immune subtype-specific signatures,and demonstrated that the signatures of macrophages,plasmacytoid dendritic cells(pDCs),CLEC9A^+DCs,natural killer(NK)cells,and plasma cells were significantly associated with improved survival outcomes in NPC.Taken together,our findings represent a unique resource providing in-depth insights into the cellular heterogeneity of NPC TME and highlight potential biomarkers for anticancer treatment and risk stratification,laying a new foundation for precision therapies in NPC. | Yu-Pei Chen Jian-Hua Yin Wen-Fei Li Han-Jie Li Dong-Ping Chen Cui-Juan Zhang Jia-Wei Lv Ya-Qin Wang Xiao-Min Li Jun-Yan Li Pan-Pan Zhang Ying-Qin Li Qing-Mei He Xiao-Jing Yang Yuan Lei Ling-Long Tang Guan-Qun Zhou Yan-Ping Mao Chen Wei Ke-Xu Xiong Hong-Bo Zhang Shi-Da Zhu Yong Hou Ying Sun Michael Dean Ido Amit Kui Wu Dong-Ming Kuang Gui-Bo Li Na Liu Jun Ma | 2020 | Cell Research2020,30,11: | 19 |
| 4 | Soil organic carbon storage and soil CO_2 flux in the alpine meadow ecosystem显示文摘High-resolution sampling,measurements of organic carbon contents and 14C signatures of selected four soil profiles in the Haibei Station situated on the northeast Tibetan Plateau,and application of 14C tracing technology were conducted in an attempt to investigate the turnover times of soil organic car-bon and the soil-CO2 flux in the alpine meadow ecosystem. The results show that the organic carbon stored in the soils varies from 22.12×104 kg C hm-2 to 30.75×104 kg C hm-2 in the alpine meadow eco-systems,with an average of 26.86×104 kg C hm-2. Turnover times of organic carbon pools increase with depth from 45 a to 73 a in the surface soil horizon to hundreds of years or millennia or even longer at the deep soil horizons in the alpine meadow ecosystems. The soil-CO2 flux ranges from 103.24 g C m-2 a-1 to 254.93 gC m-2 a-1,with an average of 191.23 g C m-2 a-1. The CO2 efflux produced from microbial decomposition of organic matter varies from 73.3 g C m-2 a-1 to 181 g C m-2 a-1. More than 30% of total soil organic carbon resides in the active carbon pool and 72.8%―81.23% of total CO2 emitted from or-ganic matter decomposition results from the topsoil horizon (from 0 cm to 10 cm) for the Kobresia meadow. Responding to global warming,the storage,volume of flow and fate of the soil organic carbon in the alpine meadow ecosystem of the Tibetan Plateau will be changed,which needs further research. | TAO Zhen1,2,SHEN ChengDe2,GAO QuanZhou1,SUN YanMin2,YI WeiXi2 & LI YingNian3 1 School of Geography and Planning,Sun Yat-sen University,Guangzhou 510275,China 2 Guangzhou Institute of Geochemistry,Chinese Academy of Sciences,Guangzhou 510640,China 3 Northwest Plateau Institute of Biology,Chinese Academy of Sciences,Xining 810001,China | 2007 | Science China Earth Sciences2007,50,7: | 12 |
| 5 | Improvement of M-U-O and K-P-W proxy signature schemes显示文摘The concept of proxy signature introduced by Mambo, Usuda, and Okamoto allows a designated person, called a proxy signer, to sign on behalf of an original signer in 1996. However, most existing proxy signature schemes does not support nonrepudiation. In this paper, we propose two secure nonrepudiable proxy signature schemes, which overcome disadvantages of M U O and K P W proxy signature schemes, respectively. The schemes proposed can withstand public key substitution attack and forge attack. In addition, our new schemes have some other advantages such as proxy signature key generation and updating using insecure channels. Our approach can also be applied to other ElGamal like proxy signature schemes. | 李继国 曹珍富 张亦辰 | 2002 | Journal of Harbin Institute of Technology(New Series)2002,9,2: | 10 |
| 6 | Six-long non-coding RNA signature predicts recurrence-free survival in hepatocellular carcinoma显示文摘BACKGROUND Recent evidence shows that long non-coding RNAs(lncRNAs) are closely related to hepatogenesis and a few aggressive features of hepatocellular carcinoma(HCC). Increasing studies demonstrate that lncRNAs are potential prognostic factors for HCC. Moreover, several studies reported the combination of lncRNAs for predicting the overall survival(OS) of HCC, but the results varied. Thus,more effort including more accurate statistical approaches is needed for exploring the prognostic value of lncRNAs in HCC.AIM To develop a robust lncRNA signature associated with HCC recurrence to improve prognosis prediction of HCC.METHODS Univariate COX regression analysis was performed to screen the lncRNAs significantly associated with recurrence-free survival(RFS) of HCC in GSE76427 for the least absolute shrinkage and selection operator(LASSO) modelling. The established lncRNA signature was validated and developed in The Cancer Genome Atlas(TCGA) series using Kaplan-Meier curves. The expression values of the identified lncRNAs were compared between the tumor and non-tumor tissues. Pathway enrichment of these lncRNAs was conducted based on the significantly co-expressed genes. A prognostic nomogram combining the lncRNA signature and clinical characteristics was constructed.RESULTS The lncRNA signature consisted of six lncRNAs: MSC-AS1, POLR2 J4, EIF3 J-AS1,SERHL, RMST, and PVT1. This risk model was significantly associated with the RFS of HCC in the TCGA cohort with a hazard ratio(HR) being 1.807(95%CI[confidence interval]: 1.329-2.457) and log-rank P-value being less than 0.001. The best candidates of the six-lncRNA signature were younger male patients with HBV infection in relatively early tumor-stage and better physical condition but with higher preoperative alpha-fetoprotein. All the lncRNAs were significantly upregulated in tumor samples compared to non-tumor samples(P < 0.05). The most significantly enriched pathways of the lncRNAs were TGF-β signaling pathway, cellular apoptosis-associated pathways, etc. The nomogram showed great utility of the lncRNA signature in HCC recurrence risk stratification.CONCLUSION We have constructed a six-lncRNA signature for prognosis prediction of HCC.This risk model provides new clinical evidence for the accurate diagnosis and targeted treatment of HCC. | Jing-Xian Gu Xing Zhang Run-Chen Miao Xiao-Hong Xiang Yu-Nong Fu Jing-Yao Zhang Chang Liu Kai Qu | 2019 | World Journal of Gastroenterology2019,25,2: | 9 |
| 7 | Osteoclast-derived apoptotic bodies couple bone resorption and formation in bone remodeling显示文摘Bone remodeling is precisely coordinated by bone resorption and formation.Apoptotic osteoclasts generate large amounts of apoptotic bodies(ABs)marking the end of the bone resorption phase,whereas the functions of osteoclast-derived ABs remain largely unknown.Here,we identified the molecular profile of ABs derived from osteoclasts at distinct differentiation stages and investigated their corresponding functions.ABs were isolated from apoptotic bone marrow macrophages,preosteoclasts,and mature osteoclasts induced by staurosporine.Proteomic signature analysis with liquid chromatography-tandem mass spectrometry suggested marked protein cargo differences among the different ABs.Further bioinformatic analysis showed that the proteomic signatures of the ABs were highly similar to those of their parental cells.Functionally,pOC-ABs induced endothelial progenitor cell differentiation and increased CD31hiEmcnhi endothelial cell formation in a murine bone defect model via their PDGF-BB cargo.mOC-ABs induced osteogenic differentiation of mesenchymal stem cells and facilitated osteogenesis via RANKL reverse signaling.In summary,we mapped the detailed proteomic landscapes of ABs derived from osteoclasts and showed that their potential biological roles are important in coupling bone formation with resorption during bone remodeling. | Qinyu Ma Mengmeng Liang Yutong Wu Fei Luo Zaisong Ma Shiwu Dong Jianzhong Xu Ce Dou | 2021 | Bone Research2021,9,1: | 8 |
| 8 | Review of Infrared signature suppression systems using optical blocking method显示文摘With rapid advancements in Infra-Red (IR) detection techniques, the range from where the IR-guided missiles are able to lock the target aircraft has increased. To avoid the detection and tracking by modern IR-guided missiles, the aircraft and helicopters also demand progress in its stealth techniques. Hence, study of Infra-Red Signature Suppression (IRSS) systems in aircraft and helicopters has become vital even in design stage. Optical blocking (masking) is one of the effective IRSS techniques used to block the Line- Of-Sight (LOS) of the hot engine parts of the exhaust geometry. This paper reviews the various patents on IR signature suppression systems based on the optical blocking method or a combination of IRSS techniques. The performance penalties generated due to installation of various IRSS methods in aircraft and helicopters are also discussed. | Nidhi Baranwal Shripad P. Mahulikar | 2019 | Defence Technology(防务技术)2019,15,3: | 8 |
| 9 | Analysis of a kind of quantum cryptographic schemes based on secret sharing显示文摘Recently, Yang et al. proposed a kind of quantum cryptographic schemes based on secret sharing. The main idea is drawn from the case, where any n participants who share a secret K can co-operate as K does. This process can be applied to encryption, authentication, signature and so on. Unfortunately, since there is no identity authentication of the share's holder, these schemes inherit the limitation of secret sharing in practice. If some participants do not follow the protocol, the protocol would be a failure at last. Moreover, these schemes encounter another serious attack. Any two participants can co-operate to defeat the schemes by sending different shares to the parties unknown to the distributor of the secret K, such that these parties can execute the protocol as well. The attack proves that it is not enough for quantum cryptographic schemes that only the secret key is secure. | ZHANG XingLan1 & JI DongYao2 1 College of Computer Science and Technology, Beijing University of Technology, Beijing 100124, China 2 State Key Laboratory of Information Security, Graduate University of Chinese Academy of Sciences, Beijing 100049, China | 2009 | Science China(Physics,Mechanics & Astronomy)2009,52,9: | 8 |
| 10 | Chemical genomics reveals inhibition of breast cancer lung metastasis by Ponatinib via c-Jun显示文摘Metastasis is the leading cause of human cancer deaths.Unfortunately,no approved drugs are available for antimetastatic treatment.In our study,high-throughput sequencing-based high-throughput screening(HTS^2)and a breast cancer lung metastasis(BCLM)-associated gene signature were combined to discover anti-metastatic drugs.After screening of thousands of compounds,we identified Ponatinib as a BCLM inhibitor.Ponatinib significantly inhibited the migration and mammosphere formation of breast cancer cells in vitro and blocked BCLM in multiple mouse models.Mechanistically,Ponatinib represses the expression of BCLM-associated genes mainly through the ERK/c-Jun signaling pathway by inhibiting the transcription of JUN and accelerating the degradation of c-Jun protein.Notably,JUN expression levels were positively correlated with BCLM-associated gene expression and lung metastases in breast cancer patients.Collectively,we established a novel approach for the discovery of anti-metastatic drugs,identified Ponatinib as a new drug to inhibit BCLM and revealed c-Jun as a crucial factor and potential drug target for BCLM.Our study may facilitate the therapeutic treatment of BCLM as well as other metastases. | Wei Shao Shasha Li Lu Li Kequan Lin Xinhong Liu Haiyan Wang Huili Wang Dong Wang | 2019 | Protein & Cell2019,10,3: | 7 |
| 11 | 基于LMS.Test.Lab某车型排气噪声问题实验分析显示文摘某试验车型在怠速和N档全油门工况下排气口噪声很明显,对车内噪声影响很大,怠速排气口和车内55 Hz对车内整体声压级贡献较大.应用比利时LMS公司的Test.Lab对上述问题进行了实验测试分析,通过更换不同状态的样件进行对比测试.结果表明:N档全油门加速行驶中,排气口噪声2阶对车内噪声2阶贡献很大,降低排气口噪声2阶声压级对车内噪声改善很明显. | 田涛 向宇 陈宏强 尚飞 | 2012 | 广西工学院学报2012,23,3: | 6 |
| 12 | Qidong: a crucible for studies on liver cancer etiology and prevention显示文摘Qidong(Jiangsu, China) has been of interest to cancer epidemiologists and biologists because, until recently, it was an endemic area for liver cancer, having amongst the highest incidence rates in the world. The establishment of the Qidong Cancer Registry together with the Qidong Liver Cancer Institute in 1972 has charted the patterns of liver cancer incidence and mortality in a stable population throughout a period of enormous economic, social, and environmental changes as well as of improvements in health care delivery. Updated incidence trends in Qidong are described. Notably, the China age-standardized incidence rate for liver cancer has dropped by over 50% in the past several decades. Molecular epidemiologic and genomic deep sequencing studies have affirmed that infection with hepatitis B virus as well as dietary exposure to aflatoxins through contamination of dietary staples such as corn, and to microcystins–blue-green algal toxins found in ditch and pond water – were likely important etiologic factors that account for the high incidence of liver cancer in this region. Public health initiatives to facilitate universal vaccination of newborns against HBV and to improve drinking water sources in this rural area, as well as economic and social mandates serendipitously facilitating dietary diversity, have led to precipitous declines in exposures to these etiologic factors, concomitantly driving substantive declines in the liver cancer incidence seen now in Qidong. In this regard, Qidong serves as a template for the global impact that a package of intervention strategies may exert on cancer burden. | Jianguo Chen Jian Zhu Gaoren Wang John D.Groopman Thomas W.Kensler | 2019 | Cancer Biology & Medicine2019,16,1: | 6 |
| 13 | Threshold proxy quantum signature scheme with threshold shared verification显示文摘A threshold proxy quantum signature scheme with threshold shared verification is proposed. An original signer could authorize a group as its proxy signers. Then only t or more of n persons in the proxy group can generate the proxy signature on behalf of the original signer and any t-1 or fewer ones cannot do that. When the proxy signature needs to be verified,any t or more of n persons belonging to the verification group can verify the message and any t-1 or fewer ones cannot verify the validity of the proxy signature. | YANG YuGuang1,3,4 & WEN QiaoYan2 1 College of Computer Science and Technology,Beijing University of Technology,Beijing 100124,China 2 State Key Laboratory of Networking and Switching Technology,Beijing University of Posts and Tele-communications,Beijing 100876,China 3 State Key Laboratory of Integrated Services Network,Xidian University,Xi’an 710071,China 4 State Key Laboratory of Information Security(Graduate University of Chinese Academy of Sciences) ,Beijing 100049,China | 2008 | Science China(Physics,Mechanics & Astronomy)2008,51,8: | 6 |
| 14 | A provable-secure and practical two-party distributed signing protocol for SM2 signature algorithm显示文摘Mobile devices are widely used for data access,communications and storage.However,storing a private key for signature and other cryptographic usage on a single mobile device can be challenging,due to its computational limitations.Thus,a number of(t,n)threshold secret sharing schemes designed to minimize private key from leakage have been proposed in the literature.However,existing schemes generally suffer from key reconstruction attack.In this paper,we propose an efficient and secure two-party distributed signing protocol for the SM2 signature algorithm.The latter has been mandated by the Chinese government for all electronic commerce applications.The proposed protocol separates the private key to storage on two devices and can generate a valid signature without the need to reconstruct the entire private key.We prove that our protocol is secure under nonstandard assumption.Then,we implement our protocol using MIRACL Cryptographic SDK to demonstrate that the protocol can be deployed in practice to prevent key disclosure. | Yudi ZHANG Debiao HE Mingwu ZHANG Kim-Kwang Raymond CHOO | 2020 | Frontiers of Computer Science2020,14,3: | 6 |
| 15 | Certificateless Sequential Aggregate Signature Scheme on NTRU Lattice显示文摘Having the advantages of certificateless signature and the aggregate signature at the same time,certificateless aggregate signature has been widely applied in e-business, e-government and software security since it was proposed in 2007. Although a number of certificateless aggregate signature schemes have been proposed, all of them are based on the classic number theory problem,which are no longer secure in the quantum era. In this paper, a certificateless sequential aggregate signature over number theory research unit lattice is proposed, which is proven to be secure in random oracle model. Moreover,we extend the new scheme into an efficient certificatebased sequential aggregate signature which is also secure in quantum era. | XIE Jia HU Yupu GAO Juntao JIANG Mingming | 2019 | Chinese Journal of Electronics2019,28,2: | 6 |
| 16 | Petrogenetic significance of high Fe/Mn ratios of the Cenozoic basalts from Eastern China显示文摘The Cenozoic basalts from eastern China show commonly high Fe/Mn ratios (average = 68.6 ± 11.5) coupled with OIB-type trace element signature. The Cenozoic basalts form the northern margin and the southern margin of the North China Craton are studied in detail. Model calculations point out that the coupling feature of high Fe/Mn ratio with OIB-type trace element signature of these basalts cannot be produced by neither pyroxene/olivine crystallization nor remelting of previously melted mantle, but require partial melting of a garnet pyroxenite-rich mantle source. Combining these features of the Cenozoic basalts with the Phanerozoic lithospheric evolution of the eastern China, we suggest that the Cenozoic basalts were derived from a garnet pyroxenite-rich mantle source associated with continental crust delamination or oceanic crust subduction. | ZHANG BinHui LIU YongSheng GAO Shan | 2008 | Science China Earth Sciences2008,51,2: | 5 |
| 17 | Functional Verification of Signature Detection Architectures for High Speed Network Applications显示文摘To meet the future internet traffic challenges, enhancement of hardware architectures related to network security has vital role where software security algorithms are incompatible with high speed in terms of Giga bits per second (Gbps). In this paper, we discuss signature detection technique (SDT) used in network intrusion detection system (NIDS). Design of most commonly used hardware based techniques for signature detection such as finite automata, discrete comparators, Knuth-Morris-Pratt (KMP) algorithm, content addressable memory (CAM) and Bloom filter are discussed. Two novel architectures, XOR based pre computation CAM (XPCAM) and multi stage look up technique (MSLT) Bloom filter architectures are proposed and implemented in third party field programmable gate array (FPGA), and area and power consumptions are compared. 10 Gbps network traffic generator (TNTG) is used to test the functionality and ensure the reliability of the proposed architectures. Our approach involves a unique combination of algorithmic and architectural techniques that outperform some of the current techniques in terms of performance, speed and power-efficiency. | M.Arun A.Krishnan | 2012 | International Journal of Automation and computing2012,9,4: | 5 |
| 18 | Investigation into the rotational bands of ^(185)Pt with the particle-rotor model显示文摘Theoretical calculations have been performed for the ν9/2+[624](i13/2) and ν7/2-[503](f7/2) bands of 185Pt in the framework of particle-rotor model. The band properties of signature splitting and configuration mixing have been analyzed. The level energy and signature splitting before the band crossing can be well interpreted by introducing triaxiality. The positive-parity yrast band is pro posed to be dominated by the ν9/2+[624](i13/2) component, while the negative-parity band shows strong mixing of ν7/2-[503](f7/2) and ν9/2-[505](h9/2) configurations. | LI GuangShun1,2, ZHOU XiaoHong1,2, ZHANG ShuangQuan3, ZHANG YuHu1 & MENG Jie3 1 Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China 2 Graduate University of Chinese Academy of Sciences, Beijing 100049, China 3 School of Physics and SK Laboratory of Nuclear Physics & Technology, Peking University, Beijing 100871, China | 2011 | Science China(Physics,Mechanics & Astronomy)2011,54,S1: | 4 |
| 19 | Identification of an immune-related gene-based signature to predict prognosis of patients with gastric cancer显示文摘BACKGROUND Gastric cancer(GC)is the most commonly diagnosed malignancy worldwide.Increasing evidence suggests that it is necessary to further explore genetic and immunological characteristics of GC.AIM To construct an immune-related gene(IRG)signature for accurately predicting the prognosis of patients with GC.METHODS Differentially expressed genes(DEGs)between 375 gastric cancer tissues and 32 normal adjacent tissues were obtained from The Cancer Genome Atlas(TCGA)GDC data portal.Then,differentially expressed IRGs from the ImmPort database were identified for GC.Cox univariate survival analysis was used to screen survival-related IRGs.Differentially expressed survival-related IRGs were considered as hub IRGs.Genetic mutations of hub IRGs were analyzed.Then,hub IRGs were selected to conduct a prognostic signature.Receiver operating characteristic(ROC)curve analysis was used to evaluate the prognostic performance of the signature.The correlation of the signature with clinical features and tumor-infiltrating immune cells was analyzed.RESULTS Among all DEGs,70 hub IRGs were obtained for GC.The deletions and amplifications were the two most common types of genetic mutations of hub IRGs.A prognostic signature was identified,consisting of ten hub IRGs(including S100A12,DEFB126,KAL1,APOH,CGB5,GRP,GLP2R,LGR6,PTGER3,and CTLA4).This prognostic signature could accurately distinguish patients into highand low-risk groups,and overall survival analysis showed that high risk patients had shortened survival time than low risk patients(P<0.0001).The area under curve of the ROC of the signature was 0.761,suggesting that the prognostic signature had a high sensitivity and accuracy.Multivariate regression analysis demonstrated that the prognostic signature could become an independent prognostic predictor for GC after adjustment for other clinical features.Furthermore,we found that the prognostic signature was significantly correlated with macrophage infiltration.CONCLUSION Our study proposed an immune-related prognostic signature for GC,which could help develop treatment strategies for patients with GC in the future. | Xiang-Ting Qiu Yu-Cui Song Jian Liu Zhen-Min Wang Xing Niu Jing He | 2020 | World Journal of Gastrointestinal Oncology2020,12,8: | 4 |
| 20 | Efficient Ring Signature Scheme Without Random Oracle from Lattices显示文摘Among post-quantum alternatives, latticebased cryptography is the most promising one, due to its simple operations, reduction from aver-age-case to worstcase hardness, and supporting of rich functionalities. Ring signature enables a user to sign anonymously on behalf of an adaptively chosen group, and has multiple applications in anonymous e-voting, anonymous authentication, whistle blowing etc. However, most lattice-based ring signature schemes were constructed in the random oracle model from lattice basis delegation and they suffer large verification key sizes as a common disadvantage. This work proposes an efficient ring signature scheme from lattice basis delegation without random oracle based on the extended split-SIS problem, whose security is approximately as hard as the worst-case SIVP problem. Our scheme is proved to be anonymous and existentially unforgeable under latticebased assumptions. Finally, the verification key size is significantly reduced to a small constant, instead of increasing linearly with the number of ring members. | GAO Wen HU Yupu WANG Baocang CHEN Jiangshan WANG Xin | 2019 | Chinese Journal of Electronics2019,28,2: | 4 |