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| 1 | Interference-assisted kaleidoscopic meta-plexer for arbitrary spin-wavefront manipulation显示文摘Achieving simultaneous polarization and wavefront control,especially circular polarization with the auxiliary degree of freedom of light and spin angular momentum,is of fundamental importance in many optical applications.Interferences are typically undesirable in highly integrated photonic circuits and metasurfaces.Here,we propose an interference-assisted metasurface-multiplexer(meta-plexer)that counterintuitively exploits constructive and destructive interferences between hybrid meta-atoms and realizes independent spin-selective wavefront manipulation.Such kaleidoscopic meta-plexers are experimentally demonstrated via two types of single-layer spinwavefront multiplexers that are composed of spatially rotated anisotropic meta-atoms.One type generates a spinselective Bessel-beam wavefront for spin-down light and a low scattering cross-section for stealth for spin-up light.The other type demonstrates versatile control of the vortex wavefront,which is also characterized by the orbital angular momentum of light,with frequency-switchable numbers of beams under linearly polarized wave excitation.Our findings offer a distinct interference-assisted concept for realizing advanced multifunctional photonics with arbitrary and independent spin-wavefront features.A variety of applications can be readily anticipated in optical diodes,isolators,and spin-Hall meta-devices without cascading bulky optical elements. | He-Xiu Xu Guangwei Hu Ying Li Lei Han Jianlin Zhao Yunming Sun Fang Yuan Guang-Ming Wang Zhi Hao Jiang Xiaohui Ling Tie Jun Cui Cheng-Wei Qiu | 2019 | Light(Science & Applications)2019，8，1： | 11 |
| 2 | Hydrogen sulfide (H_(2)S) signaling in plant development and stress responses显示文摘Hydrogen sulfide(H_(2)S)was initially recognized as a toxic gas and its biological functions in mammalian cells have been gradually discovered during the past decades.In the latest decade,numerous studies have revealed that H_(2)S has versatile functions in plants as well.In this review,we summarize H_(2)Smediated sulfur metabolic pathways,as well as the progress in the recognition of its biological functions in plant growth and development,particularly its physiological functions in biotic and abiotic stress responses.Besides direct chemical reactions,nitric oxide(NO)and hydrogen peroxide(H_(2)O2)have complex relationships with H_(2)S in plant signaling,both of which mediate protein post-translational modification(PTM)to attack the cysteine residues.We also discuss recent progress in the research on the three types of PTMs and their biological functions in plants.Finally,we propose the relevant issues that need to be addressed in the future research. | Hai Liu Jicheng Wang Jianhao Liu Tong Liu Shaowu Xue | 2021 | aBIOTECH2021，2，1： | 10 |
| 3 | Hybrid laser precision engineering of transparent hard materials:challenges,solutions and applications显示文摘Laser has been demonstrated to be a mature and versatile tool that presents great flexibility and applicability for the precision engineering of a wide range of materials over other established micromachining techniques.Past decades have witnessed its rapid development and extensive applications ranging from scientific researches to industrial manufacturing.Transparent hard materials remain several major technical challenges for conventional laser processing techniques due to their high hardness,great brittleness,and low optical absorption.A variety of hybrid laser processing technologies,such as laser-induced plasma-assisted ablation,laser-induced backside wet etching,and etching assisted laser micromachining,have been developed to overcome these barriers by introducing additional medium assistance or combining different process steps.This article reviews the basic principles and characteristics of these hybrid technologies.How these technologies are used to precisely process transparent hard materials and their recent advancements are introduced.These hybrid technologies show remarkable benefits in terms of efficiency,accuracy,and quality for the fabrication of microstructures and functional devices on the surface of or inside the transparent hard substrates,thus enabling widespread applications in the fields of microelectronics,bio-medicine,photonics,and microfluidics.A summary and outlook of the hybrid laser technologies are also highlighted. | Huagang Liu Wenxiong Lin Minghui Hong | 2021 | Light(Science & Applications)2021，10，9： | 9 |
| 4 | 一种Flash型FPGA单粒子效应测试方法设计及验证显示文摘随着现场可编程门阵列(Field Programmable Gate Array,FPGA)在现代航天领域的广泛应用,FPGA的单粒子效应(Single Event Effect,SEE)逐渐成为人们的研究热点。选择Microsemi公司Flash型FPGA分布范围最广的可编程逻辑资源VersaTile和对单粒子效应敏感的嵌入式RAM单元RAM Block作为单粒子效应的主要测试对象,提出了两种不同的单粒子效应测试方法;然后,使用仿真工具ModelSim对提出的两种电路的可行性进行了仿真验证;最后,基于自主研发的实验测试平台,在兰州重离子加速器(Heavy Ion Research Facility in Lanzhou,HIRFL)上使用86Kr束进行了束流辐照实验,实验结果表明,测试方法合理有效。 | 杨振雷 王晓辉 苏弘 刘杰 杨海波 成科 童腾 | 2015 | 核技术2015，38，2： | 9 |
| 5 | Biochemical sensing in graphene-enhanced microfiber resonators with individual molecule sensitivity and selectivity显示文摘Photonic sensors that are able to detect and track biochemical molecules offer powerful tools for information acquisition in applications ranging from environmental analysis to medical diagnosis.The ultimate aim of biochemical sensing is to achieve both quantitative sensitivity and selectivity.As atomically thick films with remarkable optoelectronic tunability,graphene and its derived materials have shown unique potential as a chemically tunable platform for sensing,thus enabling significant performance enhancement,versatile functionalization and flexible device integration.Here,we demonstrate a partially reduced graphene oxide(prGO)inner-coated and fiber-calibrated Fabry-Perot dye resonator for biochemical detection.Versatile functionalization in the prGO film enables the intracavity fluorescent resonance energy transfer(FRET)to be chemically selective in the visible band.Moreover,by measuring the intermode interference via noise canceled beat notes and locked-in heterodyne detection with Hz-level precision,we achieved individual molecule sensitivity for dopamine,nicotine and single-strand DNA detection.This work combines atomic-layer nanoscience and high-resolution optoelectronics,providing a way toward high-performance biochemical sensors and systems. | Zhongxu Cao Baicheng Yao Chenye Qin Run Yang Yanhong Guo Yufeng Zhang Yu Wu Lei Bi Yuanfu Chen Zhenda Xie Gangding Peng Shu-Wei Huang Chee Wei Wong Yunjiang Rao | 2019 | Light(Science & Applications)2019，8，1： | 8 |
| 6 | ZBP1(DAI/DLM-1) promotes osteogenic differentiation while inhibiting adipogenic differentiation in mesenchymal stem cells through a positive feedback loop of Wnt/β-catenin signaling显示文摘The lineage specification of mesenchymal stem/stromal cells(MSCs) is tightly regulated by a wide range of factors. Recently, the versatile functions of ZBP1(also known as DAI or DLM-1) have been reported in the blood circulation and immune systems.However, the biological function of ZBP1 during the lineage specification of MSCs is still unknown. In the present study, we found that ZBP1 was upregulated during osteogenesis but downregulated during adipogenesis in mouse bone marrow-derived MSCs(m BMSCs). ZBP1 was highly expressed in osteoblasts but expressed at a relatively low level in marrow adipocytes. Knockdown of ZBP1 inhibited alkaline phosphataseactivity, extracellular matrix mineralization, and osteogenesis-related gene expression in vitro and reduced ectopic bone formation in vivo. Knockdown of ZBP1 also promoted adipogenesis in MSCs in vitro. Conversely, the overexpression of ZBP1 increased the osteogenesis but suppressed the adipogenesis of MSCs. When the expression of ZBP1 was rescued, the osteogenic capacity of ZBP1-depleted m BMSCs was restored at both the molecular and phenotypic levels.Furthermore, we demonstrated that ZBP1, a newly identified target of Wnt/β-catenin signaling, was required for β-catenin translocation into nuclei. Collectively, our results indicate that ZBP1 is a novel regulator of bone and fat transdifferentiation via Wnt/β-catenin signaling. | Xuefeng Zhao Liang Xie Zhiyong Wang Jiongke Wang Hao Xu Xianglong Han Ding Bai Peng Deng | 2020 | Bone Research2020，8，2： | 8 |
| 7 | Deep learning in optical metrology:a review显示文摘With the advances in scientific foundations and technological implementations,optical metrology has become versatile problem-solving backbones in manufacturing,fundamental research,and engineering applications,such as quality control,nondestructive testing,experimental mechanics,and biomedicine.In recent years,deep learning,a subfield of machine learning,is emerging as a powerful tool to address problems by learning from data,largely driven by the availability of massive datasets,enhanced computational power,fast data storage,and novel training algorithms for the deep neural network.It is currently promoting increased interests and gaining extensive attention for its utilization in the field of optical metrology.Unlike the traditional,,physics-basedH approach,deep-learning-enabled optical metrology is a kind of,/data-drivenw approach,which has already provided numerous alternative solutions to many challenging problems in this field with better performances.In this review,we present an overview of the current status and the latest progress of deep-learning technologies in the field of optical metrology.We first briefly introduce both traditional image-processing algorithms in optical metrology and the basic concepts of deep learning,followed by a comprehensive review of its applications in various optical metrology tasks,such as fringe denoising,phase retrieval,phase unwrapping,subset correlation,and error compensation.The open challenges faced by the current deep-learning approach in optical metrology are then discussed.Finally,the directions for future research are outlined. | Chao Zuo Jiaming Qian Shijie Feng Wei Yin Yixuan Li Pengfei Fan Jing Han Kemao Qian Qian Chen | 2022 | Light(Science & Applications)2022，11，4： | 7 |
| 8 | An Overview of the Flame Retardants for Poly(vinyl chloride):Recent States and Perspective显示文摘As a versatile star product,poly(viny chloride)(PVC)has kept active in our dily lif all through since it was invented.However,the severe fire hazard andheavy smoke produced during combustion,particularly the extensively used flexible PC product,have been putzig manufacturers and researchers forages.Over the last decade,multifarious ftame retardants and smoke suppressants were developed for PVC materias.n this review combined literaturewith the results based on the research from our group,recent emerged fame retardants and smoke suppressants for PVC are introduced.Meanwhile,theflame retardant mechanisms and experimental analysis resuts are described to understand the relationship between characters of fame retardants (in-cluding chemical compositions,structures or morphologies)and fire performance of the composites.The potential substitutes for traditional harmfulflame retardant antimony trioxide are discussed aiming to the emphasis on increasing prominent environmental concerns.ln partcular,one section isdedicated to new approaches for the preparation of novel environmentally friendly and high-effciency fame retardants.is hoped that ths review wilnot only summarine the new emerged fame retardants and smoke suppressants for PVC,but also provide the new trend to prompt sequent explorationin both academic research and industrial application. | Ye-Tang Pan Yongshuai Yuan De-Yi Wang Rongjie Yang | 2020 | Chinese Journal of Chemistry2020，38，12： | 5 |
| 9 | Space-Time-Coding Digital Metasurfaces:Principles and Applications显示文摘Space-time-modulated metastructures characterized by spatiotemporally varying properties have recently attracted great interest and become one of the most fascinating and promising research fields.In the meantime,space-time-coding digital metasurfaces with inherently programmable natures emerge as powerful and versatile platforms for implementing the spatiotemporal modulations,which have been successfully realized and used to manipulate the electromagnetic waves in both the spectral and spatial domains.In this article,we systematically introduce the general concepts and working principles of space-time-coding digital metasurfaces and provide a comprehensive survey of recent advances and representative applications in this field.Specifically,we illustrate the examples of complicated wave manipulations,including harmonic beam control and programmable nonreciprocal effect.The fascinating strategy of space-time-coding opens the door to exciting scenarios for information systems,with abundant applications ranging from wireless communications to imaging and radars.We summarize this review by presenting the perspectives on the existing challenges and future directions in this fast-growing research field. | Lei Zhang Tie Jun Cui | 2021 | Research2021，，1： | 4 |
| 10 | Accelerating phase-field-based microstructure evolution predictions via surrogate models trained by machine learning methods显示文摘The phase-field method is a powerful and versatile computational approach for modeling the evolution of microstructures and associated properties for a wide variety of physical,chemical,and biological systems.However,existing high-fidelity phase-field models are inherently computa fonally expensive,requiring high-performance computing resources and sophisticated numefical integration schemes to achieve a useful degree of accuracy.In this paper,we present a computationally inexpensive,accurate,data-driven surmogate model that directly learns the microstructural evolution of targeted systems by combining phase-field and history-dependent machine-learning techniques.We integrate a statisti cally representative,low-dimensianal description of the micrastructure,obtained direcdy from phase-field simulations,with either a time-series multivariate adaptive regression splines autoregressive al garithm or a lang short-term memory neural network.The neural-network-trained surrogate model shows the bestperformance and accurately predicts the nanlinear microstructure evolutian of a two-phase mixture during spinodal decomposition in seconds,without the need for'on-the-fly'solutions of the phase-field equations of motion.We also show that the predictions from our machine learned surrogate model can be fed directly as an input into a classical high-fideli ty phase-field model in order to accelerate the high-fidelity phase field simulations by leaping in time.Such machine-learned phase-field framework opens a promising path forward to use accelerated phase field simulations for discovering,understanding,and predicting processing-microstructure-performance relationships. | David Montes de Oca Zapiain James A.Stewart Rémi Dingreville | 2021 | npj Computational Materials2021，，1： | 4 |
| 11 | Recent Advances in the Fabrication of Highly Sensitive Surface-Enhanced Raman Scattering Substrates:Nanomolar to Attomolar Level Sensing显示文摘Surface-enhanced Raman scattering(SERS)techniques have rapidly advanced over the last two decades,permitting multidisciplinary trace analyses and the potential detection of single molecules.This paper provides a comprehensive review of recent progress in strategies for the fabrication of highly sensitive SERS substrates,as a means of achieving sensing on the attomolar scale.The review examines widely used performance criteria,such as enhancement factors.In addition,femtosecond laser-based techniques are discussed as a versatile tool for the fabrication of SERS substrates.Several approaches for enhancing the performance of SERS sensing devices are also introduced,including photo-induced,transient,and liquid-interface assisted strategies.Finally,substrates for real-time sensing and biological applications are also reviewed to demonstrate the powerful analytical capabilities of these methods and the significant progress in SERS research. | Shi Bai Koji Sugioka | 2021 | Light(Advanced Manufacturing)2021，2，2： | 4 |
| 12 | A versatile photodetector assisted by photovoltaic and bolometric effects显示文摘The advent of low-dimensional materials with peculiar structure and superb band properties provides a new canonical form for the development of photodetectors.However,the limited exploitation of basic properties makes it difficult for devices to stand out.Here,we demonstrate a hybrid heterostructure with ultrathin vanadium dioxide film and molybdenum ditelluride nanoflake.Vanadium dioxide is a classical semiconductor with a narrow bandgap,a high temperature coefficient of resistance,and phase transformation.Molybdenum ditelluride,a typical two-dimensional material,is often used to construct optoelectronic devices.The heterostructure can realize three different functional modes:(i)the p-n junction exhibits ultrasensitive detection(450 nm-2μm)with a dark current down to 0.2 pA and a response time of 17μs,(ii)the Schottky junction works stably under extreme conditions such as a high temperature of 400 K,and(iii)the bolometer shows ultrabroad spectrum detection exceeding 10μm.The flexible switching between the three modes makes the heterostructure a potential candidate for next-generation photodetectors from visible to longwave infrared radiation(LWIR).This type of photodetector combines versatile detection modes,shedding light on the hybrid application of novel and traditional materials,and is a prototype of advanced optoelectronic devices. | Wei Jiang Tan Zheng Binmin Wu Hanxue Jiao Xudong Wang Yan Chen Xiaoyu Zhang Meng Peng Hailu Wang Tie Lin Hong Shen Jun Ge Weida Hu Xiaofeng Xu Xiangjian Meng Junhao Chu Jianlu Wang | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 13 | Towards a versatile point-of-care systemcombining femtosecond laser generatedmicrofluidic channels and direct laserwritten microneedle arrays显示文摘Microneedle-based microfluidic systems have a great potential to become well-accepted medical devices for simple,accurate,and painless drug delivery and lab-on-a-chip diagnostics.In this work,we report on a novel hybrid approach combining femtosecond direct laser written microneedles with femtosecond laser generated microfluidic channels providing an important step towards versatile medical point-of-care systems.Hollow microneedle arrays are fabricated by a laser system designed for two-photon polymerization applications.Compression tests of two different types of truncated cone-shaped microneedle arrays prepared from OrmoComp^(■)give information about the microneedle mechanical strength,and the results are compared to skin insertion forces.Three-dimensional microchannels are directly created inside PMMA bulk material by an ultrashort pulse laser system with vertical channels having adjustable cross-sectional areas,which allow attaching of microneedles to the microfluidic system.A comprehensive parameter study varying pulse duration and repetition rate is performed on two-photon polymerization to identify an optimal laser power range for fabricating microneedles using the same pulse duration and repetition rate as for microchannels.This addresses the advantage of a single laser system process that overcomes complex fabrication methods.A proof of concept flow test with a rhodamine B dye solution in distilled water demonstrates that the combination of microneedles and microchannels qualifies for microfluidic injection and extraction applications. | Anika Trautmann Gian-Luca Roth Benedikt Nujiqi Thomas Walther Ralf Hellmann | 2019 | Microsystems & Nanoengineering2019，5，1： | 3 |
| 14 | A Versatile Surface Bioengineering Strategy Based on Mussel-Inspired and Bioclickable Peptide Mimic显示文摘In this work,we present a versatile surface engineering strategy by the combination of mussel adhesive peptide mimicking and bioorthogonal click chemistry.The main idea reflected in this work derived from a novel mussel-inspired peptide mimic with a bioclickable azide group(i.e.,DOPA_(4)-azide).Similar to the adhesion mechanism of the mussel foot protein(i.e.,covalent/noncovalent comediated surface adhesion),the bioinspired and bioclickable peptide mimic DOPA_(4)-azide enables stable binding on a broad range of materials,such as metallic,inorganic,and organic polymer substrates.In addition to the material universality,the azide residues of DOPA_(4)-azide are also capable of a specific conjugation of dibenzylcyclooctyne-(DBCO-)modified bioactive ligands through bioorthogonal click reaction in a second step.To demonstrate the applicability of this strategy for diversified biofunctionalization,we bioorthogonally conjugated several typical bioactive molecules with DBCO functionalization on different substrates to fabricate functional surfaces which fulfil essential requirements of biomedically used implants.For instance,antibiofouling,antibacterial,and antithrombogenic properties could be easily applied to the relevant biomaterial surfaces,by grafting antifouling polymer,antibacterial peptide,and NO-generating catalyst,respectively.Overall,the novel surface bioengineering strategy has shown broad applicability for both the types of substrate materials and the expected biofunctionalities.Conceivably,the“clean”molecular modification of bioorthogonal chemistry and the universality of mussel-inspired surface adhesion may synergically provide a versatile surface bioengineering strategy for a wide range of biomedical materials. | Yu Xiao Wenxuan Wang Xiaohua Tian Xing Tan Tong Yang Peng Gao Kaiqing Xiong Qiufen Tu Miao Wang Manfred FMaitz Nan Huang Guoqing Pan Zhilu Yang | 2020 | Research2020，，1： | 3 |
| 15 | The role of TGF-beta3 in cartilage development and osteoarthritis显示文摘Articular cartilage serves as a low-friction,load-bearing tissue without the support with blood vessels,lymphatics and nerves,making its repair a big challenge.Transforming growth factor-beta 3(TGF-β3),a vital member of the highly conserved TGF-βsuperfamily,plays a versatile role in cartilage physiology and pathology.TGF-β3 influences the whole life cycle of chondrocytes and mediates a series of cellular responses,including cell survival,proliferation,migration,and differentiation.Since TGF-β3 is involved in maintaining the balance between chondrogenic differentiation and chondrocyte hypertrophy,its regulatory role is especially important to cartilage development.Increased TGF-β3 plays a dual role:in healthy tissues,it can facilitate chondrocyte viability,but in osteoarthritic chondrocytes,it can accelerate the progression of disease.Recently,TGF-β3 has been recognized as a potential therapeutic target for osteoarthritis(OA)owing to its protective effect,which it confers by enhancing the recruitment of autologous mesenchymal stem cells(MSCs)to damaged cartilage.However,the biological mechanism of TGF-β3 action in cartilage development and OA is not well understood.In this review,we systematically summarize recent progress in the research on TGF-β3 in cartilage physiology and pathology,providing up-to-date strategies for cartilage repair and preventive treatment. | Xinmei Du Linyi Cai Jing Xie Xuedong Zhou | 2023 | Bone Research2023，11，1： | 3 |
| 16 | Multiple sgRNAs facilitate base editingmediated i-stop to induce complete and precise gene disruption显示文摘Dear Editor,Gene editing is a process to introduce desired changes into targeted loci of genomic DNA.Recently,type II clustered regularly in terspaced short palindromic repeats-associated Cas9 endonuclease(CRISPR/Cas9)system has been demonstrated as a versatile tool for engineering eukaryote genome(Hsu et al.,2014),such as in mice(Zuo et al.,2017). | Kun Jia Zongyang Lu Fei Zhou Zhiqi Xiong Rui Zhang Zhiwei Liu Yu'e Ma Lei He Cong Li Zhen Zhu Dejing Pan Zhengxing Lian | 2019 | Protein & Cell2019，10，11： | 3 |
| 17 | Emerging Devices Based on Two-Dimensional Monolayer Materials for Energy Harvesting显示文摘Two-dimensional(2-D)materials of atomic thickness have attracted considerable interest due to their excellent electrical,optoelectronic,mechanical,and thermal properties,which make them attractive for electronic devices,sensors,and energy systems.Scavenging the otherwise wasted energy from the ambient environment into electrical power holds promise to address the emerging energy needs,in particular for the portable and wearable devices.The versatile properties of 2-D materials together with their atomically thin body create diverse possibilities for the conversion of ambient energy.The present review focuses on the recent key advances in emerging energy-harvesting devices based on monolayer 2-D materials through various mechanisms such as photovoltaic,thermoelectric,piezoelectric,triboelectric,and hydrovoltaic devices,as well as progress for harvesting the osmotic pressure and Wi-Fi wireless energy.The representative achievements regarding the monolayer heterostructures and hybrid devices are also discussed.Finally,we provide a discussion of the challenges and opportunities for 2-D monolayer material-based energy-harvesting devices in the development of self-powered electronics and wearable technologies. | Feng Ru Fan Wenzhuo Wu | 2019 | Research2019，，1： | 3 |
| 18 | Ultra-long-working-distance spectroscopy of single nanostructures with aspherical solid immersion microlenses显示文摘In light science and applications,equally important roles are played by efficient light emitters/detectors and by the optical elements responsible for light extraction and delivery.The latter should be simple,cost effective,broadband,versatile and compatible with other components of widely desired micro-optical systems.Ideally,they should also operate without high-numerical-aperture optics.Here,we demonstrate that all these requirements can be met with elliptical microlenses 3D printed on top of light emitters.Importantly,the microlenses we propose readily form the collected light into an ultra-low divergence beam(half-angle divergence below 1°)perfectly suited for ultra-longworking-distance optical measurements(600mm with a 1-inch collection lens),which are not accessible to date with other spectroscopic techniques.Our microlenses can be fabricated on a wide variety of samples,including semiconductor quantum dots and fragile van der Waals heterostructures made of novel two-dimensional materials,such as monolayer and few-layer transition metal dichalcogenides. | Aleksander Bogucki Lukasz Zinkiewicz Magdalena Grzeszczyk Wojciech Pacuski Karol Nogajewski Tomasz Kazimierczuk Aleksander Rodek Jan Suffczynski Kenji Watanabe Takashi Taniguchi Piotr Wasylczyk Marek Potemski Piotr Kossacki | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 19 | Carbon dioxide copolymers:Emerging sustainable materials for versatile applications显示文摘Carbon dioxide(CO_(2))is cheap,renewable,abundant,and nontoxic carbon feedstocks in chemical reactions.In the past two decades,utilization of CO_(2)in polymer science has become a meaningful topic bridging two separate subjects,namely CO_(2)valorization and sustainable polymer synthesis.This review summarizes the recent progress in CO_(2)copolymer materials from synthesis to material performance adjustment,focusing on commercialized or potential commodity sustainable materials such as biodegradable polycarbonates and new structure polyurethanes from CO_(2)-polyol building blocks. | Han Cao Xianhong Wang | 2021 | SusMat2021，1，1： | 2 |
| 20 | Versatile metal graphitic nanocapsules for SERS bioanalysis显示文摘The novel graphitic nanomaterial of metal graphitic nanocapsules(MGNs) with superior stability, unique optical properties and biocompatibility possess great potential in biomedical and bioanalytical applications. The graphitic shell can quench the background fluorescence interference from external environments via a fluorescence resonance energy transfer(FRET) process and even avoid unnecessary reactions catalyzed by inner metal core. The graphitic shell with several characteristic Raman bands itself can act as Raman signal probe or internal standard(IS), especially the 2D-band within the cellular Raman-silent region helps to reduce the interference signals from external conditions. The present context attempts to give a comprehensive overview about the preparation and unique properties of MGNs as well as their applications in SERS biodetection and bioimaging. | Shengkai Li Jiamei Xu Shen Wang Xin Xia Long Chen Zhuo Chen | 2019 | Chinese Chemical Letters2019，30，9： | 2 |
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