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A review on phospholipids and their main applications in drug delivery systems

查看全文 作  者:Jing [1]Li;Xuling [1]Wang;Ting [1]Zhang;Chunling [1]Wang;Zhenjun [1]Huang;Xiang [1]Luo;Yihui [1]Deng 高影响力作者 机构地区:[1]School of Pharmacy,Shenyang Pharmaceutical University,No.103,Wenhua Road,Shenyang 110016,China高影响力机构 出  处:《Asian Journal of Pharmaceutical Sciences》索引2015年第10卷第2期,共18页高影响力期刊 摘  要:Phospholipids have the characteristics of excellent biocompatibility and a especial amphiphilicity.These unique properties make phospholipids most appropriate to be employed as important pharmaceutical excipients and they have a very wide range of applications in drug delivery systems.The aim of this review is to summarize phospholipids and some of their related applications in drug delivery systems,and highlight the relationship between the properties and applications,and the effect of the species of phospholipids on the efficiency of drug delivery.We refer to some relevant literatures,starting from the structures,main sources and properties of phospholipids to introduce their applications in drug delivery systems.The present article focuses on introducing five types of carriers based on phospholipids,including liposomes,intravenous lipid emulsions,micelles,drug-phospholipids complexes and cochleates. 关 键 词:PHOSPHOLIPIDS BIOCOMPATIBILITY AMPHIPHILICITY Drug delivery systems
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