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ELANE:an emerging lane to selective anticancer therapy

查看全文 作  者:Boqiang [1]Peng;Jiankun [1]Hu;Xianghui [2]Fu 高影响力作者 机构地区:[1]Laboratory of Gastric Cancer and Department of Gastrointestinal Surgery,State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,Sichuan University and Collaborative Innovation Center of Biotherapy,Chengdu,Sichuan,China;[2]Division of Endocrinology and Metabolism,State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,Sichuan University and Collaborative Innovation Center of Biotherapy,Chengdu,Sichuan,China高影响力机构 出  处:《Signal Transduction and Targeted Therapy》索引2021年第6卷第11期,共2页高影响力期刊 基  金:This work was supported by the National Natural Science Foundation of China(81970561);the Ministry of Science and Technology of China(2018ZX09201018-005);the 1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(ZYJC18049). 摘  要:Recently,Cui et al.1 revealed that neutrophil elastase(ELANE)can selectively kill a wide range of cancer cells while sparing proximal non-cancer cells and significantly attenuate tumorigenesis,suggesting a promising selective and broad anticancer strategy. 关 键 词:CANCER PROXIMAL
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