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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Diabetes Promotes Cardiac Stem Cell Aging and Heart Failure, Which Are Prevented by Deletion of the p66shc Gene显示文摘 | Marcello Rota Nicole LeCapitaine Toru Hosoda Alessandro Boni Antonella De Angelis Maria Elena Padin-Iruegas Grazia Esposito Serena Vitale Konrad Urbanek Claudia Casarsa Marco Giorgio Thomas F. Lüscher Pier Giuseppe Pelicci Piero Anversa Annarosa Leri Jan | 2006 | Circulation Research2006，，1： | 1 |
| 3 | Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via en- hanced cardiac a-kit + cell proliferation and differentiation 显示文摘 | Federica L Antonia G Antonella Z | 2005 | Circ Res2005，97，8： | 1 |
| 4 | Evaluation of posttreatment response of hepatocellular carcinoma: comparison of ultrasonography with second-generation ultrasound contrast agent and multi detector CT 显示文摘 | GIUSEPPE S ANTONELLA C VITO L G | 2010 | Abdominal Imaging2010，35，： | 1 |
| 5 | Waste valorization by biotechnological conversion into added value products显示文摘 | ROSSANA L ANTONELLA A VINCENZA F | 2013 | Appl Microbioi Bioteehnol2013，97，14： | 1 |
| 6 | Exogenous high-mobility group box-1 protein induces myocardial regenerationafter infarction via enhanced cardiac C-Kin+cell proliferationand differentiation显示文摘 | Federica L Antonia G Antonella Z | 2005 | Circ Res2005，97，8： | 1 |
| 7 | Heat-oxidation stability of palm oil blended with extra virgin olive oil显示文摘 | Antonella D L Vincenzo M | 2012 | Food Chemistry2012，135，3： | 1 |
| 8 | Diabetes Promotes Cardiac Stem Cell Aging and Heart Failure, Which Are Prevented by Deletion of the p66shc Gene显示文摘 | Marcello Rota Nicole LeCapitaine Toru Hosoda Alessandro Boni Antonella De Angelis Maria Elena Padin-Iruegas Grazia Esposito Serena Vitale Konrad Urbanek Claudia Casarsa Marco Giorgio Thomas F. Lüscher Pier Giuseppe Pelicci Piero Anversa Annarosa Leri Jan | 2006 | Circulation Research2006，，1： | 1 |
| 9 | Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled trial显示文摘 | Savino M Di Stasi Antonella Giannantoni Arcangelo Giurioli Marco Valenti Germano Zampa Luigi Storti Francesco Attisani Andrea De Carolis Giovanni Capelli Giuseppe Vespasiani Robert L Stephen | 2005 | Lancet Oncology2005，，1： | 1 |
| 10 | Valuation of BWR stabilityoperating in natural circulation conditions显示文摘 | HUMBERTO V S ANTONELLA L C CLAUBIA F | 2011 | Progress in Nuclear Energy2011，53，8： | 1 |
| 11 | Carbon dioxide induced silk protein gelation for biomedical application 显示文摘 | Michael L Floren Sam Spilimbergo Antonella Motta | 2012 | Biomacromolecules2012，13，7： | 1 |
| 12 | Solid-supported monolayers and bilayers of amphilic cyclodextrins 显示文摘 | Antonella C Chcon W L Dorota I | 2007 | Langmuir2007，23，17： | 1 |
| 13 | Simple and efficient routes for the preparation of isoxazoli-dinyl nucleosides containing cytosine and 5-methyl-cytosine as new potential anti-HIV drugs显示文摘 | EVELINA C ANTONELLA C ANGELO L | 2001 | Tetrahedron2001，57，40： | 1 |
| 14 | Determination by gas chromatography/mass spec-trometry of p-phenylenediamine in hair dyes after con- version to an imine derivative显示文摘 | MARIA L D G ANTONELLA L AITK)LFO L P | 2005 | Journal of Chroma- tography A2005，1066，： | 1 |
| 15 | Os- teoblast:Osteocla-st co-cultures on silk fibroin, chitosan and PL- LA films显示文摘 | GEMMA L J ANTONELLA M M MARSHALL J | 2009 | Biomaterials2009，30，29： | 1 |
| 16 | Isolation of a hydroxytyrosol-rich extract from olive leaves( Olea europaea L ) and evaluation of its antioxidant properties and bioactivity 显示文摘 | ANTONELLA D L ALESSANDRA A GABRIELE A | 2008 | Eur Food Res Technol2008，226，： | 1 |
| 17 | Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via enhanced cardiac c-kit+ cell proliferation and differentiation显示文摘 | Federica L Antonia G Antonella Z | 2005 | Circ Res2005，97，1： | 1 |
| 18 | ^sup 11^C-Dihydrotetrabenazine PET of the Pancreas in Subjects with Long-Standing Type 1 Diabetes and in Healthy Controls显示文摘 | Goland Robin Freeby Matthew Parsey Ramin Saisho Yoshifumi Kumar Dileep Simpson Norman Hirsch Joy Prince Martin Maffei Antonella Mann J John Butler Peter C Van Heertum Ronald Leibel Rudolph L Ichise Masanori Harris Paul E | 2009 | The Journal of Nuclear Medicine2009，，3： | 1 |
| 19 | Multicomponent reactions studies:Yonemitsu-type trimolecular condensations promoted by Ti(Ⅳ)derivatives显示文摘 | Stéphane G Bérangère L Antonella F | 2010 | Tetrahedron2010，66，16： | 1 |
| 20 | Mild to moderate reduction of a yon willebrand factor cleaving protease(ADAMTS-13) in pregnant women with HELLP microangiopathic syndrome显示文摘 | Antonella L Edoardo R Cinzia C | 2003 | J of hematology2003，88，9： | 1 |
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