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| 1 | Chemical composition of PM_(2.5) during winter in Tianjin,China显示文摘PM2.5 samples for 24 h were collected during winter in Tianjin,China. The ambient mass concentration and chemical composition of the PM2.5 were determined. Ionic species were analyzed by ion chromatog-raphy,while carbonaceous species were determined with the IMPROVE thermal optical reectance(TOR) method,and inorganic elements were measured by inductively coupled plasma-atomic emission spec-trometer. The daily PM2.5 mass concentrations ranged from 48.2 to 319.2 g/m3 with an arithmetic average of 144.6 g/m3. The elevated PM2.5 in winter was mostly attributed to combustion sources such as vehicle exhaust,heating,cooking and industrial emissions,low wind speeds and high relative humidity(RH) ,which were favorable for pollutant accumulation and formation of secondary pollutants. By chem-ical mass balance,it was estimated that about 89.1% of the PM2.5 mass concentrations were explained by carbonaceous species,secondary particles,crustal matters,sea salt and trace elements. Organic material was the largest contributor,accounting for about 32.7% of the total PM2.5 mass concentrations. SO42-,NO3-,Cl- and NH4+ were four major ions,accounting for 16.6%,11.5%,4.7% and 6.0%,respectively,of the total mass of PM2.5. | Jinxia Gu Zhipeng Bai Weifang Li Liping Wu Aixia Liu Haiyan Dong Yiyang Xie | 2011 | Particuology2011，9，3： | 60 |
| 2 | A land use regression for predicting NO_2 and PM_(10) concentrations in different seasons in Tianjin region,China显示文摘Land use regression (LUR) model was employed to predict the spatial concentration distribution of NO2 and PM10 in the Tianjin region based on the environmental air quality monitoring data. Four multiple linear regression (MLR) equations were established based on the most significant variables for NO2 in heating season (R2 = 0.74), and non-heating season (R2 = 0.61) in the whole study area; and PM10 in heating season (R2 = 0.72), and non-heating season (R2 = 0.49). Maps of spatial concentration distribution for NO2 and PM10 were obtained based on the MLR equations (resolution is 10 km). Intercepts of MLR equations were 0.050 (NO2, heating season), 0.035 (NO2, non-heating season), 0.068 (PM10, heating season), and 0.092 (PM10, non-heating season) in the whole study area. In the central area of Tianjin region, the intercepts were 0.042 (NO2, heating season), 0.043 (NO2, non-heating season), 0.087 (PM10, heating season), and 0.096 (PM10, non-heating season). These intercept values might imply an area’s background concentrations. Predicted result derived from LUR model in the central area was better than that in the whole study area. R2 values increased 0.09 (heating season) and 0.18 (non-heating season) for NO2, and 0.08 (heating season) and 0.04 (non-heating season) for PM10. In terms of R2, LUR model performed more effectively in heating season than non-heating season in the study area and gave a better result for NO2 compared with PM10. | Li Chen Zhipeng Bai Shaofei Kong Bin Han Yan You Xiao Ding Shiyong Du Aixia Liu | 2010 | Journal of Environmental Sciences2010，22，9： | 12 |
| 3 | Optimizing protein and lipid levels in practical diet for juvenile northern snakehead fish(Channa argus)显示文摘A 3×3 factorial feeding trial was conducted to evaluate the production response of juvenile northern snakehead fish(Channa argus). Nine diets containing 3 protein levels(45%, 48% and 51%) and 3 lipid levels(9%,12% and 15%) were formulated and fed to triplicate groups of juvenile northern snakehead(15.78 ± 0.09 g/fish) for 8 weeks. The formulated diets were named as P45 L9, P45 L12, P45 L15, P48 L9,P48 L12, P48 L15, P51 L9, P51 L12 and P51 L15(P-Protein, L-Lipid), respectively. Fish fed diets with the lowest protein and lipid combination(P45 L9) had the lowest growth performance. Weight gains(WG) of fish fed the 4 diets P48 L12, P48 L15, P51 L9, and P51 L12 were not significantly different(P> 0.05), but significantly higher(P < 0.05) than those of fish fed the other diets. Fish fed diets P48 L12 and P48 L15 had significantly lower(P < 0.05) feed conversion ratios(FCR) than the rest of the treatments. Protein retentions(PR) among fish fed the diets P45 L12, P45 L15, P48 L12, P48 L15, P51 L9, and P51 L12 were similar and significantly higher(P < 0.05) than those of fish fed the remaining diets. Protein sparing effect was observed in the treatments when fish was fed diets containing 45% or 48% dietary protein levels with dietary lipid increased from 9% to12%. Fish fed diets with 9% lipid tended to have lower viscerosomatic index(VSI), hepatosomatic index(HSI),and whole-body lipid. Increasing dietary protein level significantly increased(P < 0.05) liver moisture and lipid while dietary lipid level increased liver lipid. Intestinal lipase activity increased significantly(P < 0.05)with increasing dietary lipid and protein levels while intestinal a-amylase and protease activities were not significantly influenced(P > 0.05) by dietary treatments. Based on these results, the diet containing 48%protein with either 12% or 15% lipid is the optimal for supporting growth and feed utilization of juvenile northern snakehead under the current testing conditions. | Gladstone Sagada Jianming Chen Binqian Shen Aixia Huang Lihui Sun Jianhu Jiang Chunhua Jin | 2017 | Animal Nutrition2017，，2： | 10 |
| 4 | Land cover mapping using time series HJ-1 / CCD data显示文摘It is very difficult to have remote sensing data with both high spatial resolution and high temporal frequency; thus, two categories of land-use mapping methodology have been developed separately for coarser resolution and finer resolution data. The first category uses time series of data to retrieve the variation of land surface for classification, which are usually used for coarser resolution data with high temporal frequency. The second category uses fine spatial resolution data to classify different land surface. With the launch of Chinese satellite constellation HJ-1in 2008, four 30 m spatial resolution CCDs with about 360 km coverage for each one onboard two satellites made a revisit period of two days, which brought a new type of data with both high spatial resolution and high temporal frequency. Therefore, by taking the spatiotemporal advantage of HJ-1/CCD data we propose a new method for finer resolution land cover mapping using the time series HJ-1/CCD data, which can greatly improve the land cover mapping accuracy. In our two study areas, the very high resolution remote sensing data within Google Earth are used to validate the land cover mapping results, which shows a very high mapping accuracy of 95.76% and 83.78% and a high Kappa coefficient of 0.9423 and 0.8165 in the Dahuofang area of Liaoning Province and the Heiquan area of Gansu Province respectively. | ZHONG Bo MA Peng NIE AiHua YANG AiXia YAO YanJuan Lü WenBo ZHANG Hang LIU QinHuo | 2014 | Science China Earth Sciences2014，57，8： | 9 |
| 5 | Triglycerides and ratio of triglycerides to high-density lipoprotein cholesterol are better than liver enzymes to identify insulin resistance in urban middle-aged and older non-obese Chinese without diabetes显示文摘 | Sun Yu Li Wenjuan Hou Xinguo Wang Chuan Li Chengqiao Zhang Xiuping Yang Weifang Ma Zeqiang Wang Weiqing Ning Guang Zheng Huizhen Ma Aixia Song Jun Lin Peng Liang Kai Liu Fuqiang Gong Lei Wang Meijian Xiao Juan Yan Fei Yang Junpeng Wang Lingshu Tian Meng Liu Jidong Zhao Ruxing Zhu Ping Chen Li | 2014 | Chinese Medical Journal2014，，10： | 7 |
| 6 | Primary research on neoplasm needle track implantation metastasis after radioactive seeds implantation and preventive measures显示文摘Objective:To observe the possibility of neoplasm needle track implantation after radioactive seeds implantation and seek preventive measures to avoid it.Methods:Superficial tissue of 250 seeding needle cores and 250 stylophores employed in neoplasm radioactive seeds implantation was smeared on slides to search for tumor cells.All patients received chemotherapy or endocrine therapy after operations.Ultrasound B-mode or computer tomography(CT)was performed at 10th day,30th day,60th day,and 180th day post operation to detect neoplasm implantation metastasis through needle tracks. Results:Positive cells were found on 13 of 250(5.20%)cores,and 7 of 250(2.80%)stylophores.The difference was not sta- tistically significant(P>0.05).The positive cells frequency of needles those traversed distance less than 3 cm in normal tissue was 6.19%(13/210),while the frequency of the others those traversed longer distance in normal tissue was 2.41%(7/290). The positive cells frequency of needles traversing different distances in normal tissues is significantly different(P<0.05).No neoplasm was detected through needle tracks by ultrasound B-mode or CT in 180 days after operation.Conclusion:Tumor cells could ablate into the needle track during radioactive seed implantation.Some preventive measures,such as optimization of pre-operation and intra-operation treatment plan,chemotherapy or endocrine therapy after operation,may be beneficial to avoid the implantation metastasis of neoplasm in seeding needle tracks. | Juan Wang Weihong Gong Huige Fan Aixia Sui Na Zhao Yongqing Shen | 2007 | The Chinese-German Journal of Clinical Oncology2007，6，4： | 5 |
| 7 | Gene characterization and molecular pathway analysis of reverse thermosensitive genic male sterility in eggplant(Solanum melongena L.)显示文摘The naturally occurring mutant eggplant line 05ms was identified with reverse thermosensitive genic male sterility(rTGMS),but its temperature-responsive fertility mechanisms remain largely unknown.Here,we studied the flower morphology,anther cellular structure,and genome-wide gene expression of this rTGMS line.Candidate genes for thermosensitive male sterility during the microspore development of 05ms and the temperature-insensitive line S63 under low-temperature(LT)and high-temperature(HT)conditions were identified.Under LT,tapetum cells were vacuolated and had delayed disintegration in 05ms.RNA-seq analysis indicated that DEGs were enriched in the KEGG pathways‘plant hormone signal transduction’,‘starch and sucrose metabolism’,and‘phenylpropanoid biosynthesis’.We identified two genes,4CLL1(Sme2.5_00368.1_g00010.1)and CKI1(Sme2.5_10056.1_g00002.1),which could potentially regulate eggplant anther development and may be candidate genes for rTGMS.Finally,we propose a working model of anther abortion for rTGMS in eggplant.CKI1 responds to LT stress and causes expression changes in genes related to anther development,such as 4CLL1,and the cellular structure of the tapetum becomes abnormal,causing male sterility.The findings of this study explain the underlying molecular mechanisms of male sterility in eggplant rTGMS lines. | Bing Li Xueping Chen Yanrong Wu Aixia Gu Jingjing Zhang Shuangxia Luo Xiurui Gao Jianjun Zhao Xiuqing Pan Shuxing Shen | 2019 | Horticulture Research2019，6，1： | 5 |
| 8 | Pharmacokinetics, tissue distribution and excretion study of tetrandrine in rats显示文摘汉防己甲素是从中药汉防己的块根中提取的一种双苄基异喹啉类生物碱,能够逆转肿瘤细胞多药耐药、诱导细胞凋亡,临床上用于治疗恶性肿瘤。本研究的目的是评价汉防己甲素在大鼠体内血液药动学、组织分布和排泄过程。大鼠通过静脉给予汉防己甲素注射液(10.00 mg/kg),应用高效液相色谱法测定血浆和各组织中的药物浓度,利用药动学软件DAS 2.0对实验数据进行计算分析。实验结果表明,汉防己甲素的血浆蛋白结合率为68.7%,属于较高蛋白结合率药物;组织分布药量由高到低依次是肺>心>肝>肾>脾;肾脏排泄是汉防己甲素主要的排泄途径,其通过尿液、胆汁和粪便排泄占给药剂量的13.09%。汉防己甲素在肝脏的AUC0–∞是血浆中AUC0–∞的20倍,表明其对肝脏有较高的亲和力;在所有的组织中肝脏CL是最低的,表明汉防己甲素清除缓慢,可能导致蓄积。因此,临床上长期药时,需要调整肝肾功能损伤病人的用药剂量,必要时进行治疗药物监测。 | Aixia Ju Yuhong Kang Qingdan Xue Qiuhong Li | 2015 | Journal of Chinese Pharmaceutical Sciences2015，24，8： | 5 |
| 9 | Generation and characterization of an anti-GP73 monoclonal antibody for immunoblotting and sandwich ELISA显示文摘Recently,serum Golgi protein 73(GP73) levels have been found to be elevated in patients with hepatocellular carcinoma(HCC),and GP73 has been proposed as a novel marker for HCC.However,GP73 levels in patients remain controversial due to the specificity of the anti-GP73 antibody-based enzyme linked immunosorbent assay(ELISA).Therefore,an anti-GP73 antibody with high specificity was highly demanded.In the present study,by hybridoma screening,we generated an anti-GP73 monoclonal antibody(mAb) designated as 6A2 using recombinant GP73 protein produced by prokaryotic expression.The specificity of 6A2 was evaluated by Western blotting,immunohistochemistry and immunoprecipitation.The results showed that 6A2 recognized GP73 in both native and denatured forms.In addition,we have developed a sandwich ELISA using 6A2 and GP73 polyclonal antibody generated in New Zealand white rabbits according to standard procedures,and measured the serum GP73 level of patients using this assay.Our results showed that serum GP73 levels of HCC patients were significantly higher than those of healthy controls(P = 0.0036).Furthermore,for the first time,GP73 serum level was found to be elevated in patients with breast cancer compared with healthy controls(P = 0.0172). | Aixia Zhang Brian Cao | 2012 | The Journal of Biomedical Research2012，26，6： | 4 |
| 10 | Aerosol-assisted submicronγ-Fe2O3/C spheres as a promising heterogeneous Fenton-like catalyst for soil and groundwater remediation:Transport,adsorption and catalytic ability显示文摘This research reports a novel heterogeneous Fenton-like catalyst which could freely move through the model sediments and easily seize the pollutants in addition to efficiently catalyze H2O2,well suitable for soil and groundwater remediation.Herein,submicron y-Fe2O3/C spheres were synthesized through a facile one-step aerosol-based process.In a series of column tests,these spheres exhibit better transport ability due to their optimal size,conforming to the prediction by the Tufenkji-Elimelech filtration theo ry.Meanwhile,y-Fe2O3/C spheres could act as a strong adsorbent for organic pollutants owing to the presence of carbon,thereby providing a driving force to gather contaminants into their vicinity and facilitating the reaction.In addition,immobilization of y-Fe2O3 nanoparticles into carbon spheres protects iron oxides from aggregation,and thus retains the number of active sites for catalytic decomposition of H2O2.Hence,the system containing the as-prepared y-Fe2O3/C spheres and H2O2 shows the high removal efficiency and degradation efficiency in the remediation of recalcitrant organic contaminants such as methylene blue and sulfamethoxazole. | Jingjing Zhan Mingfei Li Xiujuan Zhang Yu An Weiqi Sun Aixia Peng Hao Zhou | 2020 | Chinese Chemical Letters2020，31，3： | 3 |
| 11 | Circadian clock gene expression regulates cancer cell growth through glutaminase显示文摘夫酸安是为恶意的肿瘤房间的必要氨基酸。使夫酸安产生代射变化的 Glutaminase 到达肿瘤立即在最大的增长前评估的最大的 expressionin。肿瘤房间在日子期间以不同的率成长。我们 postulatedthat 在肿瘤房间的 glutaminase 的活动服从于生理节奏的钟基因的规定。我们测量了由在在六 equispaced 时间的肝和 tumorcells 的即时聚合酶链反应的西方的污点分析和生理节奏的钟基因表示削尖的 glutaminaseby 在一张 12/12 h 光 / 黑暗时间表的单个鼠标今日。结果显示出 thatthe 忍受肿瘤的鼠标,在正常下面日报条件,生理节奏地被乘火车,由正常主机 locomotoractivity 节奏和有韵律的肝钟基因表示思考了。在这些老鼠以内的肿瘤生理节奏地也被组织,由生理节奏的钟基因(Bmal1 ) 的 asreflected 表示。是很显著的的,是肾类型 glutaminase 也在一样的模式 withtumor 显示出生理节奏的节奏在肝癌症异种皮移植模型的生理节奏的钟基因表示,有条件地显示那禁止 glutaminaseactivity 可以为癌症提供一个新目标治疗。 | Aixia Huang Bingbo Bao H Rex Gaskins Haijun Liu Xueli Zhang Liwen Lu Shan Gao Yihai Shi Ming Zhang Yuanzhou Shan Jing Feng Guoxiang Yao | 2014 | Acta Biochimica et Biophysica Sinica2014，46，5： | 3 |
| 12 | Implementing two optimal economical quantum cloning with superconducting quantum interference devices in a cavity显示文摘We propose a unified scheme to implement the optimal 1→ 3economical phase-covariant quantum cloning and optimal 1→3 economical real state cloning with superconducting quantum interference devices (SQUIDs) in a cavity.During this process,no transfer of quantum information between the SQUIDs and cavity is required.The cavity field is only virtually excited.The scheme is insensitive to cavity decay.Therefore,the scheme can be experimentally realized in the range of current cavity QED techniques. | YE Liu HU GuiYu LI AiXia | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，1： | 3 |
| 13 | MG132, a proteasome inhibitor, attenuates pressure-overload-induced cardiac hypertrophy in rats by modulation of mitogen-activated protein kinase signals显示文摘Proteasome 禁止者涉及细胞周期控制,生长并且煽动性的发信号,和有丝分裂的细胞的 transcriptional 规定。最近的研究建议了特定的 proteasome 禁止者 MG132 可以在 vitro 压制 cardiomyocyte 肥大。然而,内在的分子的机制不是清楚的。在这研究,我们在 vivo 在心脏的肥大和相关分子的机制上调查了长期的 MG132 处理的效果。MG132 (0.1 mg/kg/day ) intraperitoneally 与腹的大动脉的 banding (AAB ) 被注射到老鼠 8 个星期。结果证明有显著地稀释的 MG132 的处理留给室(LV ) myocyte 区域, LV 重量 / 身体重量,和肺重量 / 身体重量比率,减少的 LV 心脏舒张的直径和墙厚度,并且在 AAB 老鼠的增加的部分弄短。AAB 在心脏的 myocytes 导致了 ERK1/2, JNK1,和 p38 的 phosphorylation。在 AAB 老鼠的 ERK1/2 和 JNK1 的提高的 phosphorylation 层次被 MG132 处理显著地颠倒。在结论,我们的结果建议有 MG132 的长期的处理稀释 pressure-overload-induced 心脏的肥大并且通过表明小径的 ERK1/2 和 JNK1 的规定在 AAB 老鼠改进心脏的功能。 | Baolin Chen Yuedong Ma Rongsen Meng Zhaojun Xiong Chengxi Zhang Guangqin Chen Aixia Zhang Yugang Dong | 2010 | Acta Biochimica et Biophysica Sinica2010，42，4： | 3 |
| 14 | Reactive oxygen species regulate auxin levels to mediate adventitious root induction in Arabidopsis hypocotyl cuttings显示文摘Adventitious root(AR)formation from leafy stem cuttings is critical for breeding of many forest and horticultural species.In addition to the plant hormone auxin,wound-induced signaling caused by the cutting excision is also essential for AR initiation.Here we found that reactive oxygen species(ROS)are rapidly generated at the excision site as a wound-induced signal and propagated throughout the hypocotyl cut-ting after excision of the Arabidopsis(Arabidopsis thaliana)primary root.ROS propagation was not ob-served in the presence of an NADPH oxidase inhibitor(diphenylene iodonium chloride)or in a knockout mu-tant of the NADPH oxidase gene respiratory burst oxi-dase homolog protein D(RBOHD).Respiratory burst oxidase homolog protein D was specifically upregulatedin hypocotyl cuttings at 0.5 h post excision(hpe).To-gether,these data suggest that RBOHD mediates ROS propagation in hypocotyl cuttings.We also found that auxin levels increased significantly in the shoot apex at 5 hpe and at the base of the cutting at 6 hpe;these effects were blocked by treatment with ROS scav-engers.Consistent with this,transcript levels of auxin biosynthesis and polar-transport genes generally in-creased between 1 to 6 hpe.Collectively,our results suggest that wound-induced ROS participate in AR in-duction through regulation of auxin biosynthesis and transport. | Aixia Huang Yongshun Wang Yangyang Liu Guodong Wang Xiaoping She | 2020 | Journal of Integrative Plant Biology2020，62，7： | 3 |
| 15 | Genomic footprints of Kam Sweet Rice domestication indicate possible migration routes of theDongpeople inChina andprovide resources for future rice breeding显示文摘The Dong people are one of China’s 55 recognized ethnic minorities,but there has been a long-standing debate about their origins.In this study,we performed whole-genome resequencing of Kam Sweet Rice(KSR),a valuable,rare,and ancient rice landrace unique to the Dong people.Through comparative genomic analyses of KSR and other rice landraces from south of the Yangtze River Basin in China,we provide evidence that the ancestors of the Dong people likely originated from the southeast coast of China at least 1000 years ago.Alien introgression and admixture in KSR demonstrated multiple migration events in the history of the Dong people.Genomic footprints of domestication demonstrated characteristics of KSR that arose from artificial selection and geographical adaptation by the Dong people.The key genes GS3,Hd1,and DPS1(related to agronomic traits)and LTG1 and MYBS3(related to cold tolerance)were identified as domestication targets,reflecting crop improvement and changes in the geographical environment of the Dong people during migration.A genome-wide association study revealed a candidate yield-associated gene,Os01g0923300,a specific haplotype in KSR that is important for regulating grain number per panicle.RNA-sequencing and quantitative reverse transcription-PCR results showed that this gene was more highly expressed in KSR than in ancestral populations,indicating that it may have great value in increasing yield potential in other rice accessions.In summary,our work develops a novel approach for studying human civilization and migration patterns and provides valuable genomic datasets and resources for future breeding of high-yield and climate-resilient rice varieties. | Chunhui Liu Tianyi Wang Huicha Chen Xiaoding Ma Chengzhi Jiao Di Cui Bing Han Xiaobing Li Aixia Jiao Renchao Ruan Dayuan Xue Yanjie Wang Longzhi Han | 2023 | Molecular Plant2023，16，2： | 3 |
| 16 | Lacunar infarction with leukoaraiosis may aggravate cognitive dysfunction显示文摘This study semi-quantitatively analyzed the effects of leukoaraiosis.Patients with moderate or severe lacunar infarction were found to exhibit low scores on the Montreal Cognitive Assessment Scale (F=12.02,P=0.000),and prolonged P300 Cz2.0 latency (F=16.04,P=0.000).Correlation analysis revealed that the occurrence of leukoaraiosis was negatively correlated with Montreal Cognitive Assessment scores (r=-0.416,P=0.000),and positively correlated with P300 Cz2.0 latency (r=0.538,P=0.000).These findings indicate that leukoaraiosis aggravates cognitive impairment in patients with lacunar infarction,such that more severe leukoaraiosis is associated with more severe cognitive decline. | Dejin Sun Xueqin Zhang Penju Liu Jiechun Chen Jinxia Cao Aixia Zhuang Qinghong Zeng Shouqin Feng Yi Zhang Jiandong Jiang | 2011 | Neural Regeneration Research2011，6，31： | 3 |
| 17 | Preparation of microsized silver crystals with different morphologies by a wet-chemical method显示文摘A wet-chemical method was presented for preparation of spherical,flowerlike,hexagonal,and triangular microsized silver crystals.Well-defined particles were prepared by mixing of iron(Ⅱ) sulfate heptahydrate solution with silver nitrate solution at the presence of different modifiers with high-speed stirring at 8-20℃.It is found that the diameters of resulting products are 0.6-6.0 μm and the morphologies of the silver microcrystals are greatly affected by the introduced modifiers.It is concluded that the microsized silver crystals with different morphologies can be synthesized by introducing appropriate modifiers at appropriate experimental parameters.Scanning electron microscopy and X-ray diffraction were used to characterize the resulting products. | CAI Xionghui ZHM Aixia | 2010 | Rare Metals2010，29，4： | 3 |
| 18 | Comparative transcriptome analysis reveals defense responses against soft rot in Chinese cabbage显示文摘Pectobacterium carotovorum ssp.carotovorum(Pcc)is a necrotrophic bacterial species that causes soft rot disease in Chinese cabbage.In this study,plants harboring the resistant mutant sr gene,which confers resistance against Pcc,were screened from an 800 M2 population mutated by ethyl methane sulfonate(EMS)and scored in vitro and in vivo for lesion size.The transcript profiles showed~512 differentially expressed genes(DEGs)between sr and WT plants occurring between 6 and 12 h postinoculation(hpi),which corresponded to the important defense regulation period(resistance)to Pcc in Chinese cabbage.The downstream defense genes(CPK,CML,RBOH MPK3,and MPK4)of pathogen pattern-triggered immunity(PTI)were strongly activated during infection at 12 hpi in resistant mutant sr;PTI appears to be central to plant defense against Pcc via recognition by three putative pattern recognition receptors(PRRs;BrLYM1-BrCERK1,BrBKK1/SERK4-PEPR1,BrWAKs).Pcc triggered the upregulation of the jasmonic acid(JA)and ethylene(ET)biosynthesis genes in mutant sr,but auxins and other hormones may have affected some negative signals.Endogenous hormones(auxins,JAs,and SA),as well as exogenous auxins(MEJA and BTH),were also verified as functioning in the immune system.Concurrently,the expression of glucosinolate and lignin biosynthesis genes was increased at 12 hpi in resistant mutant sr,and the accumulation of glucosinolate and lignin also indicated that these genes have a functional defensive role against Pcc.Our study provides valuable information and elucidates the resistance mechanism of Chinese cabbage against Pcc infection. | Mengyang Liu Fang Wu Shan Wang Yin Lu Xueping Chen Yanhua Wang Aixia Gu Jianjun Zhao Shuxing Shen | 2019 | Horticulture Research2019，6，1： | 2 |
| 19 | HIV-specific CD8^+ T cell responses to HXB2 Gag and Nef peptide pools in Chinese HIV/AIDS patients显示文摘HXB2 is primarily used as a template strain in developing HIV vaccines in Europe and the US. However,it is not yet known whether the strain can induce strong HIV-specific CD8+ T cell responses in Chinese HIV/AIDS patients. In the present study,two groups of subjects were investigated:9 AIDS patients and 7 long-term nonprogressors (LTNPs). HIV-specific CD8+ T cell responses were examined in all patients through the ELISPOT assay. CD4+ T cell counts,CD8+ T cell counts,viral load and HIV subtype of each patient were also measured. Thailand B virus strain was identified among all the patients. The breadth and magnitude of HIV-specific CD8+ T cell responses in the LTNPs group are greater than those in the AIDS group (P<0.01). There is a positive correlation between magnitude of HIV-specific CD8+ T cell responses and CD4+ T cells,and a negative correlation between HIV-specific CD8+ T cell responses and mean viral load. In summary,the HIV-specific CD8+ T cell responses to the HXB2 Gag and Nef peptide pools are considerable in Chinese HIV/AIDS patients infected with Thailand B virus strain. HIV-1 vaccines based on HXB2 strain that can induce extensive immunity may be helpful for Chinese. | ZHANG HongWei,QIU ZhiFeng,JIAO Yang,WANG AiXia & LI TaiSheng Department of Infectious Diseases,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Beijing 100730,China | 2009 | Science China(Life Sciences)2009，52，9： | 2 |
| 20 | Morphology-Controlled Synthesis of CeO_2 Microstructures and Their Room Temperature Ferromagnetism显示文摘Gear-shape CeO_2 microstructures have been synthesized via a facile hydrothermal method with Ce(NO_3)_3·6H_2O as the cerium source, NH_4HCO_3 as both the precipitator and the carbon source, and cetyltrimethyl ammonium bromide(CTAB) as the surfactant. X-ray diffraction(XRD) inferred that the synthesized CeO_2 microstructures exhibited a fluorite structure. The band gap(Eg) of CeO_2 samples is larger than that of bulk. X-ray photoelectron spectroscopy(XPS) showed that there are plenty of Ce^(3+) ions and oxygen vacancies at the surface of CeO_2 samples. All the synthesized CeO_2 samples exhibited the room temperature ferromagnetism, and the saturation magnetization increases with the increases of lattice parameter and Eg. The room temperature ferromagnetism mechanism of gear-shape CeO_2 is mainly attributed to the influence Ce^(3+) ions. | Fanming Meng Zhenghua Fan Cheng Zhang Youdi Hu Tao Guan Aixia Li | 2017 | Journal of Materials Science & Technology2017，33，5： | 2 |
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