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| 1 | Modified chitosan hydrogels as drug delivery and tissue engineering systems:present status and applications显示文摘Chitosan,a natural cationic polysaccharide,is prepared industrially by the hydrolysis of the aminoacetyl groups of chitin,a naturally available marine polymer.Chitosan is a non-toxic,biocompatible and biodegradable polymer and has attracted considerable interest in a wide range of biomedical and pharmaceutical applications including drug delivery,cosmetics,and tissue engineering.The primary hydroxyl and amine groups located on the backbone of chitosan are responsible for the reactivity of the polymer and also act as sites for chemical modification.However,chitosan has certain limitations for use in controlled drug delivery and tissue engineering.These limitations can be overcome by chemical modification.Thus,modified chitosan hydrogels have gained importance in current research on drug delivery and tissue engineering systems.This paper reviews the general properties of chitosan,various methods of modification,and applications of modified chitosan hydrogels. | Tapan Kumar Giri Amrita Thakur Amit Alexander Ajazuddin Hemant Badwaik Dulal Krishna Tripathi | 2012 | Acta Pharmaceutica Sinica B2012，2，5： | 7 |
| 2 | Prediction and optimization of machining forces using oxley’s predictive theory and RSM approach during machining of WHAs显示文摘Tungsten heavy alloys have come up as one of the best alternatives for high density fragmenting devices and armor piercing ammunition.Machining is mandatory for obtaining the final shapes of such kind of ammunitions.However,due to high density and elastic stiffness of WHAs,cutting forces will be higher than for most of the metals and alloys;thus,making the machining operation challenging.The machining variable,namely,cutting force components are significantly influenced by the cutting parameters.This paper makes use of Oxley’s predictive analytical model in conjunction with Johnson-Cook constitutive equation to predict forces under different speed and feed combinations during machining of 95 W tungsten heavy alloy.The cutting forces,so predicted by Ml,are considered as input data for the optimization of cutting parameters(cutting speed and feed)using Response Surface Method(RSM). | Chithajalu Kiran Sagar Tarun Kumar Amrita Priyadarshini Amit Kumar Gupta | 2019 | Defence Technology(防务技术)2019，15，6： | 1 |
| 3 | A critical review on Nepal Dock(Rumex nepalensis):A tropical herb with immense medicinal importance显示文摘Rumex nepalensis Spreng.(Polygonaceae) commonly known as Nepal Dock has wide-spectrum therapeutic potencies and is extensively used for centuries in traditional medicine systems. The leaves of this plant are edible and a rich source of natural antioxidants. They act as a possible food supplement and are largely used in pharmaceutical industry. Extracts and metabolites from this plant exhibits pharmacological activities including anti-inflammatory, antioxidant, antibacterial, antifungal, antiviral, insecticidal, purgative, analgesic, antipyretic, anti-algal, central nervous system depressant, genotoxic, wound healing and skeletal muscle relaxant activity. Due to its remarkable biological activities, it has the potential to act as a rich source of drug against life threatening diseases. However, more studies are needed to scientifically validate the traditional uses of this plant, beside isolating and identifying their active principles and characterizing the mechanisms of action. We present herein a critical account of its botany, ecology, traditional uses, phytoconstituent profile and major pharmacological activities reported in recent years and therefore will provide a source of information on this plant for further studies. | Samrin Shaikh Varsha Shriram Amrita Srivastav Pranoti Barve Vinay Kumar | 2018 | Asian Pacific Journal of Tropical Medicine2018，11，7： | 1 |
| 4 | Chrysanthemum Growth Gains from Beneficial Microbial Interactions and Fertility Improvements in Soil Under Protected Cultivation显示文摘An investigation was undertaken to analyse the influence of microbial inoculants on growth and enzyme activities elicited, and soil microbiome of two varieties of Chrysanthemum morifolium Ramat, which were grown under protected mode of cultivation. Rhizosphere soil sampling at 45 and 90 DAT(days after transplanting of cuttings) revealed up to four- to five-fold enhancement in the activity of defence-, and pathogenesisrelated, and antioxidant enzymes, relative to the uninoculated control. Plant growth and soil microbial parameters, especially soil microbial biomass carbon and potential nitrification exhibited significant increases over control. Available soil nitrogen concentrations showed 40%–44% increment in inoculated treatments. Scanning electron microscopy of the root tissues revealed biofilm-like aggregates and individual short bits of cyanobacterial filaments. Analyses of DGGE profiles of archaeal and bacterial communities did not show temporal variations(between 45 and 90 DAT). However,distinct influences on the number and abundance of phylotypes due to microbial inoculants were recorded. The inoculants — Cyanobacterial consortium(BF1- 4) and Anabaena sp.–Trichoderma sp. biofilm(An-Tr) were particularly promising in terms of the plant and soil related parameters,and remained distinct in the DGGE profiles generated. The effect of Trichoderma viride–Azotobacter biofilm on soil bacterial and archaeal communities was unique and distinct as a separate cluster. This study highlights that microbial inoculants exert positive effects, which are specific even to the rhizosphere soil microbiome of chrysanthemum varieties tested. Such inoculants can serve as soil fertility enhancing options in protected floriculture. | Radha Prasanna Amrita Kanchan Simranjit Kaur Balasubramanian Ramakrishnan Kunal Ranjan Mam Chand Singh Murtaza Hasan Anil Kumar Saxena Yashbir Singh Shivay | 2016 | Horticultural Plant Journal2016，2，4： | 1 |
| 5 | Advances in the development of built-in diagnostic system for filament wound composite structures 显示文摘 | Qing x P Beard S J Amrita Kumar | 2006 | Composites Science and Technology2006，，66： | 1 |
| 6 | Anti-inflammatory activity of Acanthus ilicifolius显示文摘 | K.T. Mani Senthil Kumar Bapi Gorain Dilip K. Roy Zothanpuia Samir K. Samanta Mintu Pal Prova Biswas Amrita Roy Dipan Adhikari Sanmoy Karmakar Tuhinadri Sen | 2008 | Journal of Ethnopharmacology2008，，1： | 1 |
| 7 | Latent Cytomegalovirus Infection Exacerbates Experimental Colitis显示文摘 | Chukwuma Onyeagocha Mohammad S. Hossain Amrita Kumar Rheinallt M. Jones John Roback Andrew T. Gewirtz | 2009 | The American Journal of Pathology2009，，5： | 1 |
| 8 | Vari- able Forgetting Factor LS Mgorithm for Polynomial Channel Model显示文摘 | Amit Kumar Kohli Amrita Rai Meher Krishna Patel | 2011 | ISRN Signal Processing2011，，2011： | 1 |
| 9 | Relevance of Helicobacter pylori genotypes in gastric pathology and its association with plasma malondialdehyde and nitric oxide levels显示文摘 | Santosh K. Tiwari G. Manoj Vishwas Sharma G. Sivaram R. Saikant Avinash Bardia Varun K. Sharma Zakia Abid Aleem A. Khan M. Aejaz Habeeb C. M. Habibullah B. Santhosh Kumar Amrita Nandan | 2010 | Inflammopharmacology2010，，2： | 1 |
| 10 | Advances in the development of built-in diagnostic system for filament wound composite structures显示文摘 | Xinlin P Qing Shawn J Beard Amrita Kumar | 2006 | Composites Science and Technology2006，66，： | 1 |
| 11 | Receptor modeling for source apportionment of polycyclic aromatic hydrocarbons in urban atmosphere显示文摘 | Kunwar P. Singh Amrita Malik Ranjan Kumar Puneet Saxena Sarita Sinha | 2008 | Environmental Monitoring and Assessment2008，，1： | 1 |
| 12 | Recovery of lithium and cobalt from waste lithium ion batteries of mobile phone 显示文摘 | Manis Kumar JHA Anjan KUMARI Amrita Kumari JHA | 2013 | Waste Management2013，33，： | 1 |
| 13 | Recovery of lithium and cobalt from waste lithium ion batteries of mobile phone显示文摘 | Manis Kumar Jha Anjian Kumari Amrita Kumari Jha | 2013 | Waste Management2013，33，： | 1 |
| 14 | Pharmacological studies on Buchanania lanzan Spreng.-A focus on wound healing with particular reference to anti-biofilm properties显示文摘Objective:To evaluate the wound healing activity of the methanolic root extract of Buchanania lanzan Spreng.(B.lanzan),with a focus on antimicrobial and anti-biofilm properties.Methods:The extract was evaluated for its wound healing properties(excision and incision models)as evident from the analysis of tensile strength and wound contraction.The extract was also screened for antibacterial properties against different Cram positive and Gram negative bacterial strains.B.lanzan was also studied for its effect on biofilm formation and disruption of preformed biofilms.The synergistic effect of B.lanzan was determined in combination with gentamicin.Results:Topical application of B.lanzan(10%w/w ointment)significantly increased(40.84%)the tensile strength in the incision wound model.B.lanzan also showed significant wound healing activity in excision model and such significant activity was observed from the 9th day.Whereas Soframycin displayed significant wound healing activity from the 6th day.It was found that root extracts of B.lanzan revealed significant inhibition against all tested pathogens.B.lanzan displayed antimicrobial activity against Cram positive(MIC 0.625 mg/mL)and Cram negative(MIC0.625-1.25 mg/mL).B.lanzan was able to reduce biofilm formation and also caused disruption of preformed biofilms in a manner similar to ciprofloxacin.However,gentamicin was found to be ineffective against biofilms formed by Gram negative organism.According to the fractional inhibitory concentration index,B.lanzan displayed synergistic activity when it was combined with gentamicin.Conclusions:From this study it may be concluded that the root extract of B.lanzan revealed significant wound healing potential,which was supported and well correlated with pronounced antibacterial activity of the tested plant parts. | Ashok Pattnaik Ratul Sarkar Amrita Sharma Kirendra Kumar Yadav Alekh Kumar Paramita Roy Avijit Mazumder Sanmoy Karmakar Tuhinadri Sen | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，12： | 1 |
| 15 | Drosophila melanogaster as an indispensable model to decipher the mode of action of neurotoxic compounds显示文摘Exposure to some toxic compounds causes structural and behavioral anomalies associated with the neurons in the later stage of life.Those toxic compounds are termed as a neurotoxicant,which can be a physical factor,a toxin,an infection,radiation,or maybe a drug.The incongruities caused due to a neurotoxicant further depend on the toxicity of the compound.More importantly,the neurotoxicity of the compound is associated with the concentration and the time point of exposure.The neurodevelopmental defect appears depending on the toxicity of the compound.A neurodevelopmental defect may be associated with a delay in developmental time,defective growth,structural abnormality of many organs,including sensory organs,behavioral abnormalities,or death in the fetus stage.Numerous model organisms are employed to assess the effect of neurotoxicants.The current review summarizes several methods used to check the effect of neurotoxicant and their effect using the model organism Drosophila melanogaster. | MONALISA MISHRA PUNYATOYA PANDA BEDANTA KUMAR BARIK AMRITA MONDAL MRUTUNJAYA PANDA | 2023 | BIOCELL2023，47，1： | 0 |
| 16 | Recent updates on nano-phyto-formulations based therapeutic intervention for cancer treatment显示文摘Cancer is a leading cause of death globally,with limited treatment options and several limitations.Chemotherapeutic agents often result in toxicity which long-term conventional treatment.Phytochemicals are natural constituents that are more effective in treating various diseases with less toxicity than the chemotherapeutic agents providing alternative therapeutic approaches to minimize the resistance.These phytoconstituents act in several ways and deliver optimum effectiveness against cancer.Nevertheless,the effectiveness of phyto-formulations in the management of cancers may be constrained due to challenges related to inadequate solubility,bioavailability,and stability.Nanotechnology presents a promising avenue for transforming current cancer treatment methods through the incorporation of phytochemicals into nanosystems,which possess a range of advantageous characteristics such as biocompatibility,targeted and sustained release capabilities,and enhanced protective effects.This holds significant potential for future advancements in cancer management.Herein,this review aims to provide intensive literature on diverse nanocarriers,highlighting their applications as cargos for phytocompounds in cancer.Moreover,it offers an overview of the current advancements in the respective field,emphasizing the characteristics that contribute to favourable outcomes in both in vitro and in vivo settings.Lastly,clinical development and regulatory concerns are also discussed to check on the transformation of the concept as a promising strategy for combination therapy of phytochemicals and chemotherapeutics that could lead to cancer management in the future. | ABHISHEK WAHI MAMTA BISHNOI NEHA RAINA MEGHNA AMRITA SINGH PIYUSH VERMA PIYUSH KUMAR GUPTA GINPREET KAUR HARDEEP SINGH TULI MADHU GUPTA | 2024 | Oncology Research2024，32，1： | 0 |
| 17 | Numerical Investigation of the Thermal Distortion in Multi-Laser Powder Bed Fusion(ML-PBF)Additive Manufacturing of Inconel 625显示文摘Metal additive manufacturing,especially laser powder bed fusion(L-PBF),is increasingly being used to fabricate complex parts with fine features.Emerging L-PBF systems have large build volumes and several lasers that op-erate simultaneously.Hence,they can produce large and complex parts at reduced costs and short build times.However,the thermal distortion remains a critical challenge.Hence,a thorough understanding of the impact of multiple lasers on part distortion in multi-laser PBF(ML-PBF)is imperative.Although experimental investigation is possible,a more conducive approach is to design and create suitable predictive models to understand the impact of multiple lasers consolidating a part into layers.To fulfill this goal,in this study,a commercially available and widely used thermo-mechanical model,Netfabb,was used to investigate the effects of multiple lasers for com-plex scan patterns such as raster,spiral,and Hilbert on the temperature distribution and thermal distortion.The results show that the thermal distortion is minimal for the spiral scan pattern.Additionally,multiple lasers were found to decrease the build time(as expected)while maintaining or reducing the thermal distortion compared with their single-laser counterparts for all scan patterns(except Hilbert).Therefore,the newly developed ML-PBF predictive model is capable of providing critical insights into the effects of using multiple lasers,thereby opening new possibilities for the faster production of complex parts.In the future,small-scale computational models will be expanded to include large-scale parts,and probabilistic models will be developed to establish correlations. | Amit Kumar Ball Amrita Basak | 2023 | Chinese Journal of Mechanical Engineering(Additive Manufacturing Frontiers)2023，2，4： | 0 |
| 18 | Strain induced changes in performance of strained-Si/strained-Si1-yGey/relaxed-Si1-xGex MOSFETs and circuits for digital applications显示文摘Growing a silicon(Si) layer on top of stacked Si-germanium(Ge) compressive layer can introduce a tensile strain on the former, resulting in superior device characteristics. Such a structure can be used for high performance complementary metal-oxide-semiconductor(CMOS) circuits. Down scaling metal-oxide-semiconductor field-effect transistors(MOSFETs) into the deep submicron/nanometer regime forces the source(S) and drain(D) series resistance to become comparable with the channel resistance and thus it cannot be neglected. Owing to the persisting technological importance of strained Si devices, in this work, we propose a multi-iterative technique for evaluating the performance of strained-Si/strained-Si_(1-y)Ge_y/relaxed-Si_(1-x)Ge_x MOSFETs and its related circuits in the presence of S/D series resistance, leading to the development of a simulator that can faithfully plot the performance of the device and related digital circuits. The impact of strain on device/circuit performance is also investigated with emphasis on metal gate and high-k dielectric materials. | Kumar Subindu Kumari Amrita Das Mukul K | 2017 | Journal of Central South University2017，24，6： | 0 |
| 19 | Design and Analysis of Graphene Based Tunnel Field Effect Transistor with Various Ambipolar Reducing Techniques显示文摘The fundamental advantages of carbon-based graphene material,such as its high tunnelling probability,symmetric band structure(linear dependence of the energy band on the wave direction),low effective mass,and characteristics of its 2D atomic layers,are the main focus of this research work.The impact of channel thickness,gate under-lap,asymmetric source/drain doping method,workfunction of gate contact,and High-K material on Graphene-based Tunnel Field Effect Transistor(TFET)is analyzed with 20 nm technology.Physical modelling and electrical characteristic performance have been simulated using the Atlas device simulator of SILVACO TCAD with user-defined material syntax for the newly included graphene material in comparison to silicon carbide(SiC).The simulation results in significant suppression of ambipolar current to voltage characteristics of TFET and modelled device exhibits a significant improvement in subthreshold swing(0.0159 V/decade),the ratio of Ion/Ioff(1000),and threshold voltage(-0.2 V with highly doped p-type source and 0.2 V with highly doped n-type drain)with power supply of 0.5 V,which make it useful for low power digital applications. | Puneet Kumar Mishra Amrita Rai Nitin Sharma Kanika Sharma Nitin Mittal Mohd Anul Haq Ilyas Khan ElSayed M.Tag El Din | 2023 | Computers, Materials & Continua2023，，7： | 0 |
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