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| 1 | The Plant Vascular System: Evolution, Development and Functions显示文摘The emergence of the tracheophyte-based vascular system of land plantshad major impacts on the evolution of terrestrial biology, in general,through its role in facilitating the development of plants with increasedstature, photosynthetic output, and ability to colonize a greatly expandedrange of environmental habitats. Recently, considerable progress hasbeen made in terms of our understanding of the developmental andphysiological programs involved in the formation and function of theplant vascular system. In this review, we first examine the evolutionaryevents that gave rise to the tracheophytes, followed by analysis of thegenetic and hormonal networks that cooperate to orchestrate vasculardevelopment in the gymnosperms and angiosperms. The two essentialfunctions performed by the vascular system, namely the delivery of resources (water, essential mineralnutrients, sugars and amino acids) to the various plant organs and provision of mechanical support arenext discussed. Here, we focus on critical questions relating to structural and physiological propertiescontrolling the delivery of material through the xylem and phloem. Recent discoveries into the role ofthe vascular system as an effective long-distance communication system are next assessed in termsof the coordination of developmental, physiological and defense-related processes, at the whole-plantlevel. A concerted effort has been made to integrate all these new findings into a comprehensive pictureof the state-of-the-art in the area of plant vascular biology. Finally, areas important for future researchare highlighted in terms of their likely contribution both to basic knowledge and applications to primaryindustry. | William J. Lucas Andrew Groover Raffael Lichtenberger Kaori Furuta Shri-Ram Yadav Yk Helariutta Xin-Qiang He Hiroo Fukuda Julie Kang Siobhan M. Brady John W. Patrick John Sperry Akiko Yoshida Ana-Flor López-Millan Michael A. Grusak Pradeep Kachroo | 2013 | Journal of Integrative Plant Biology2013,55,4: | 30 |
| 2 | Pancreatic ductal adenocarcinoma: Risk factors, screening, and early detection显示文摘Pancreatic cancer is the fourth most common cause of cancer-related deaths in the United States, with over 38000 deaths in 2013. The opportunity to detect pancreatic cancer while it is still curable is dependent on our ability to identify and screen high-risk populations before their symptoms arise. Risk factors for developing pancreatic cancer include multiple genetic syndromes as well as modifiable risk factors. Genetic conditions include hereditary breast and ovarian cancer syndrome, Lynch Syndrome, familial adenomatous polyposis, Peutz-Jeghers Syndrome, familial atypical multiple mole melanoma syndrome, hereditary pancreatitis, cystic fibrosis, and ataxia-telangiectasia; having a genetic predisposition can raise the risk of developing pancreatic cancer up to 132-fold over the general population. Modifiable risk factors, which include tobacco exposure, alcohol use, chronic pancreatitis, diet, obesity, diabetes mellitus, as well as certain abdominal surgeries and infections, have also been shown to increase the risk of pancreatic cancer development. Several largevolume centers have initiated such screening protocols, and consensus-based guidelines for screening high-riskgroups have recently been published. The focus of this review will be both the genetic and modifiable risk factors implicated in pancreatic cancer, as well as a review of screening strategies and their diagnostic yields. | Andrew E Becker Yasmin G Hernandez Harold Frucht Aimee L Lucas | 2014 | World Journal of Gastroenterology2014,20,32: | 24 |
| 3 | Wind resource estimates with an analog ensemble approach显示文摘 | Vanvyve Emilie Delle Monache Luca Monaghan Andrew J | 2015 | Renewable Energy2015,74,: | 1 |
| 4 | Hyperthermic Intraperitoneal Chemotherapy with Oxaliplatin for Peritoneal Carcinomatosis Arising from Appendix: Preliminary Results of a Survival Analysis显示文摘 | Eric Marcotte MD Lucas Sideris MD FRCSC Pierre Drolet MD FRCPC Andrew Mitchell MD Suzanne Frenette BPharm MSc BCOP Guy Leblanc MD FRCSC Yves E. Leclerc MD FRCSC FACS Pierre Dubé MD MSc FRCSC FACS | 2008 | Annals of Surgical Oncology2008,,10: | 1 |
| 5 | Etho vision: a versatile video tracking system for automation of behavioral experiments 显示文摘 | Lucas PJJ Noldus Andrew JS | 2001 | Behavior Research Methods Instruments & Computers2001,33,3: | 1 |
| 6 | Stability and Performance for Saturated Systems via Quadratic and Non-quadratic Lyapunov Functions 显示文摘 | Hu Tingshu Teel Andrew R Zaccarian Luca | 2006 | IEEE Transactions on Automatic Control (S0018-9286)2006,51,11: | 1 |
| 7 | EthoVision:A versatile video tracking system for automation of behavioral experiments 显示文摘 | NOLDUS P LUCAS ANDREW J S | 2001 | Behavior Research Methods Instruments & Computers2001,33,3: | 1 |
| 8 | Anti-windup synthesis for linear control systems with input saturation: Achieving regional, nonlinear performance显示文摘 | Tingshu Hu Andrew R. Teel Luca Zaccarian | 2007 | Automatica2007,,2: | 1 |
| 9 | Adrenergic Nerves Govern Circadian Leukocyte Recruitment to Tissues显示文摘 | Christoph Scheiermann Yuya Kunisaki Daniel Lucas Andrew Chow Jung-Eun Jang Dachuan Zhang Daigo Hashimoto Miriam Merad Paul S. Frenette | 2012 | Immunity2012,,: | 1 |
| 10 | Targeted cytotoxic somatostatin analog AN-162 inhibits growth of human colon carcinomas and increases sensitivity of doxorubicin resistant murine leukemia cells显示文摘 | Florian Hohla Stefan Buchholz Andrew V. Schally Awtar Krishan Ferenc G. Rick Luca Szalontay Andrea Papadia Gabor Halmos Frank Koster Elmar Aigner Christian Datz Stephan Seitz | 2010 | Cancer Letters2010,,1: | 1 |
| 11 | Results of treatment of distal rectal carcinoma since the introduction of total mesorectal excision: a single unit experience, 1994–2003显示文摘 | Antonio Chiappa Roberto Biffi Andrew P. Zbar Fabrizio Luca Cristiano Crotti Emilio Bertani Francesca Biella Giulia Zampino Roberto Orecchia Nicola Fazio Marco Venturino Cristiano Crosta Gian Carlo Pruneri Carmine Grassi Bruno Andreoni | 2005 | International Journal of Colorectal Disease2005,,3: | 1 |
| 12 | Does Obesity Influence Lymph Node Harvest among Patients Undergoing Colectomy for Colon Cancer?显示文摘 | Damadi Amir A Julien Lucas Arrangoiz Rodrigo Raiji Manish Weise David Saxe Andrew W | 2008 | The American Surgeon2008,,: | 1 |
| 13 | Stability properties of reset systems显示文摘 | Dragan Ne?i? Luca Zaccarian Andrew R. Teel | 2008 | Automatica2008,,8: | 1 |
| 14 | Enhanced vibration control of an ultrasonic cutting process显示文摘 | Margaret Lucas George Graham Andrew Smith | 1996 | Ultra- sonics1996,34,: | 1 |
| 15 | Nonlinear scheduled anti-windup design for linear systems显示文摘 | Luca Zaccarian Andrew R Teel | 2004 | IEEE Transactions On Automatic Control2004,49,11: | 1 |
| 16 | Cryothermal Ablation Treatment of Atrial Flutter—Experience with a New 9 French 8 mm Tip Catheter显示文摘 | Annibale S. Montenero Nicola Bruno Francesco Zumbo Andrea Antonelli Luigi Fiocca Luca Barbieri Francesca Bernardi Peter Andrew Vincenzo Affinito | 2005 | Journal of Interventional Cardiac Electrophysiology2005,,1: | 1 |
| 17 | ADIC-An Extensible Automatic Differentiation Tool Yor ANSI-C 显示文摘 | CHRISTIAN BISCHOF LUCAS ROH ANDREW MAUER | 1997 | Software-Practice and Experience1997,27,12: | 1 |
| 18 | Magnetic resonance imaging of white matter diseases of prematurity显示文摘 | Mary A. Rutherford Veena Supramaniam Ashraf Ederies Andrew Chew Laura Bassi Michela Groppo Mustafa Anjari Serena Counsell Luca A. Ramenghi | 2010 | Neuroradiology2010,,6: | 1 |
| 19 | Advancesin multiphase flow CFD erosion analysis显示文摘 | Deng Peng Afshin Pak Luca Andrew Low | 2013 | OffshoreTechnology Conference2013,,3: | 1 |
| 20 | Microfabricated intracortical extracellular matrix-microelectrodes for improving neural interfaces显示文摘Intracortical neural microelectrodes,which can directly interface with local neural microcircuits with high spatial and temporal resolution,are critical for neuroscience research,emerging clinical applications,and brain computer interfaces(BCI).However,clinical applications of these devices remain limited mostly by their inability to mitigate inflammatory reactions and support dense neuronal survival at their interfaces.Herein we report the development of microelectrodes primarily composed of extracellular matrix(ECM)proteins,which act as a bio-compatible and an electrochemical interface between the microelectrodes and physiological solution.These ECM-microelectrodes are batch fabricated using a novel combination of micro-transfer-molding and excimer laser micromachining to exhibit final dimensions comparable to those of commercial silicon-based microelectrodes.These are further integrated with a removable insertion stent which aids in intracortical implantation.Results from electrochemical models and in vivo recordings from the rat’s cortex indicate that ECM encapsulations have no significant effect on the electrochemical impedance characteristics of ECM-microelectrodes at neurologically relevant frequencies.ECM-microelectrodes are found to support a dense layer of neuronal somata and neurites on the electrode surface with high neuronal viability and exhibited markedly diminished neuroinflammation and glial scarring in early chronic experiments in rats. | Wen Shen Suradip Das Flavia Vitale Andrew Richardson Akshay Ananthakrishnan Laura A.Struzyna Daniel P.Brown Naixin Song Murari Ramkumar Timothy Lucas DKacy Cullen Brian Litt Mark G.Allen | 2018 | Microsystems & Nanoengineering2018,4,1: | 1 |