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5篇 您的检索式：作者名="Antonia Martinetti"

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		题名	作者	年代	出处	被引量
	1	Role of MGMT as biomarker in colorectal cancer显示文摘O6-methylguanine DNA methyltransferase(MGMT) gene promoter methylation plays an important role in colorectal carcinogenesis, occurring in about 30%-40% of metastatic colorectal cancer. Its prognostic role has not been defined yet, but loss of expression of MGMT, which is secondary to gene promoter methylation, results in an interesting high response to alkylating agents such as dacarbazine and temozolomide. In a phase 2 study on heavily pre-treated patients with MGMT methylated metastatic colorectal cancer, temozolomide achieved about 30% of disease control rate. Activating mutations of RAS or BRAF genes as well as mismatch repair deficiency may represent mechanisms of resistance to alkylating agents, but a dose-dense schedule of temozolomide may potentially restore sensitivity in RAS-mutant patients. Further development of temozolomide in MGMT methylated colorectal cancer includes investigation of synergic combinations with other agents such as fluoropyrimidines and research for additional biomarkers, in order to better define the role of temozolomide in the treatment of individual patients.	Alessandro Inno Giuseppe Fanetti Maria Di Bartolomeo Stefania Gori Claudia Maggi Massimo Cirillo Roberto Iacovelli Federico Nichetti Antonia Martinetti Filippo de Braud Ilaria Bossi Filippo Pietrantonio	2014	World Journal of Clinical Cases2014，2，12：	10
	2	Humoral Response to Recombinant Hepatitis B Virus Vaccine at Birth: Role of HLA and Beyond显示文摘	Miryam Martinetti Annalisa De Silvestri Cesare Belloni Annamaria Pasi Carmine Tinelli Angela Pistorio Laura Salvaneschi Giorgio Rondini Maria Antonia Avanzini Mariaclara Cuccia	2000	Clinical Immunology2000，，：	2
	3	Are capecitabine and oxaliplatin (XELOX) suitable treatments for progressing low-grade and high-grade neuroendocrine tumours?显示文摘	Emilio Bajetta Laura Catena Giuseppe Procopio Sara Dosso Ettore Bichisao Leonardo Ferrari Antonia Martinetti Marco Platania Elena Verzoni Barbara Formisano Roberto Bajetta	2007	Cancer Chemotherapy and Pharmacology2007，，：	2
	4	Prognostic Value of Circulating Tumor Markers in Patients with Pseudomyxoma Peritonei Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy显示文摘	Dario Baratti MD Shigeki Kusamura MD PhD Antonia Martinetti MD Ettore Seregni MD Barbara Laterza MD Daniela G. Oliva MD Marcello Deraco MD	2007	Annals of Surgical Oncology2007，，8：	2
	5	Circulating CA125 in Patients with Peritoneal Mesothelioma Treated with Cytoreductive Surgery and Intraperitoneal Hyperthermic Perfusion显示文摘	Dario Baratti MD Shigeki Kusamura MD Antonia Martinetti MD Ettore Seregni MD Daniela G. Oliva MD Barbara Laterza MD Marcello Deraco MD	2007	Annals of Surgical Oncology2007，，2：	1

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