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| 1 | 缺血性脑卒中患者血压与住院临床结局的相关性显示文摘高血压是脑卒中的主要危险因素。研究表明,在缺血性脑卒中患者中,由于压力依赖性的脑血液流向缺血区域,脑卒中后高血压有益。然而,其他研究显示,脑卒中后的高血压与短期再发性脑卒中、脑出血性转化和脑水肿发生率升高有关。关于血压与脑卒中短期临床结局相关性的观察性研究结论相互矛盾。此外,关于血压的搏动组分(脉压)或稳定组分(平均动脉压)与临床结局相关性的数据有限。 | Bangalore S Schwamm L Smith EE Hellkamp AS Suter RE Xian Y Schulte PJ Fonarow GC Bhatt DL 练桂丽 叶鹏 | 2017 | 中华高血压杂志2017，25，11： | 5 |
| 2 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 3 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 4 | The incidence of intra-operative awareness during general anesthesia in china:a multi-center observational study显示文摘 | Xu L Wu AS Yue Y | | Acta Anaesthesiologica Scandinavica0，，： | 2 |
| 5 | Micro-computed tomography evaluation of trabeular bone structure on loaded mice tail vertebrae显示文摘 | Walsh A Lu Y el at | 2003 | Spine2003，28，2： | 1 |
| 6 | Definition and classification of chronic kidney disease: a position statement from Kidney Disease : Improving Global Outcomes ( KD1GO ) 显示文摘 | Levey AS Eckardt KU Tsukamoto Y | 2005 | Kidney Int2005，67，： | 1 |
| 7 | ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree显示文摘 | Nakashima Y Plump AS Raines EW | | 0，，： | 1 |
| 8 | Megakaryocyte ploidy and platelet changes in human diabetes and atherosclerosis 显示文摘 | Brown AS Hong Y Belder A | 2009 | Arte- fioscler Thromb Vasc Bio12009，17，4： | 1 |
| 9 | Knowledge, attitudes and practices towards malaria among primary school pupils in Ndirande, Blantyre, Malawi显示文摘 | Muula AS Chimalizeni Y | 2004 | Trop Doct2004，34，2： | 1 |
| 10 | Concerning the significance of paraoxonase-1 and SR-B1 genes in atherosclerosis显示文摘 | Rodríguez Esparragón F Hernández Trujillo Y Macías Reyes A | 2006 | Rev Esp Cardiol2006，59，2： | 1 |
| 11 | Multiple pathways of repair of DNA double-strand breaks in mammalian chromosomes显示文摘 | Lin Y Lukacsovich T Waldman AS | 1999 | Mol Cell Biol1999，19，： | 1 |
| 12 | Anticoagulation therapy for stroke prevention in atrial fibrillation: how well do randomized trial translate into clinical practice?显示文摘 | GO AS HYLEK EM CHANG Y | 2003 | JAMA2003，290，20： | 1 |
| 13 | Prognostic value of pressure-flow study in surgical treatment of benign prostatic obstruction显示文摘 | Gotoh M Yoshikawa Y Kondo AS | 1999 | World J Urol1999，17，5： | 1 |
| 14 | Akt/protein kinase B is consti- tutively active in non-small cell lung cancer ceils and promotes cel- lularsurvival and resistance to chemotherapy and radiation 显示文摘 | Brognard J Clark AS Ni Y | 2001 | Cancer Res2001，61，10： | 1 |
| 15 | The poly(ADP-ribose) polymerases (PARPs):new roles in intracellular transport显示文摘 | Abd Elmageed ZY Naura AS Errami Y | | 0，，01： | 1 |
| 16 | MRI of blood flow of the human retina 显示文摘 | Peng Q Zhang Y Nateras as van Osch MJ Duong TQ | | Magn Reson Med0，65，6： | 1 |
| 17 | Arson laser photocoagulation induced modification of gene expression in the retina 显示文摘 | Wilson AS Hobbs BG Shen W Y | 2003 | Invest Ophthalmol Vis Sci2003，44，： | 1 |
| 18 | Orofacial pain conditions and impact on quality of life in community-dwelling elderly people in Hong Kong显示文摘 | McMillan AS Wong MC | 2007 | J Orofac Pain2007，21，1： | 1 |
| 19 | Role of water channels in fluid transport studied by phenotype analysis of aquaporin knockout mice显示文摘 | Verkman AS Yang B Song Y | 2000 | Exp Physiol2000，85，： | 1 |
| 20 | Relationships be tween protein and mineral during enamel development in normal and genetically altered mice 显示文摘 | Smith CE Hu Y Richardson AS | 2011 | Eur J Oral Sci2011，119，1： | 1 |
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