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21篇 您的检索式:作者名="Won HH"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2Phase II clinical trial of lobaplatin (D-19466) in pretreated patients with small cell lung cancer显示文摘Fiebig HH Henb H Pawet won 1996Onkologie1996,19,4:1
3Inactivating mutations in NPC1L1 and protection from coronary heart disease显示文摘Stitziel NO Won HH Morrison AC 2014Engl J Med2014,371,22:1
4A comprehensive 1000 Ge- nomes-based genome-wide association meta-analysis of coronary ar- tery disease 显示文摘Nikpay M Goel A Won HH 2015Nat Genet2015,47,10:1
5Polymorphic markers associated with severe oxaliplatin-Induced,chronic peripheral neuropathy in colon cancer patients显示文摘Won HH Lee J Park YS 2012Cancer2012,118,11:1
6Inactivating mutations in NPC1L1and protection from coronary heart disease 显示文摘Myocardial Infarction Genetics Consortium Investigators Stitziel NO Won HH 2014N Engl J Med2014,371,22:1
7Exome sequenc- ing identifies rare LDLR and APOA-V alleles con- ferring risk for myocardial infarction显示文摘Do R Stitzie Won HH 2015Nature2015,518,7537:1
8Polymorphic markers associated with severe oxaliplatin-induced,chronic peripheral neuropathy in colon cancer patients显示文摘Won HH Lee J Park JO 0,,11:1
9Estradiol pre- vents the focal cerebral ischemic injury-induced de- crease of forkhead transcription factors phosphoryl- ation显示文摘Won CK Ji HH Koh PO 2006Neurosci Lett2006,398,12:1
10Evaluation of lysyl oxidase-like 1 gene polymorphisms in pseudoexfoliation syndrome in a Korean population显示文摘PARK DO Y WON HH CHO HK KEE C 2013Mol Vis2013,19,:1
11Small cell lung cancer(SCLC) among patients who are never smokers 显示文摘Varghese AM Yu HA Won HH 2013J Clin Oneol2013,,:1
12Transcatheter N-butyl cyanoacrylate embolization of pseudoaneurysms显示文摘Song HH Won YD Kim YJ 0,,:1
13Differentially expressed genes in human peripheral blood as potential markers for statin response显示文摘Won HH Kim SR Bang OY 2012J Mol Med(Berl)2012,90,2:1
14The endovascular management of saccular posterior inferior cerebellar artery aneurysms显示文摘Song HH Won YD Kim YJ 2008Korean J Radiol2008,9,:1
15Acute lymphoblastic leukemia without the Philadelphia chromosome occurring in chronic myelogenous leukemia with the Philadelphia chromosome显示文摘Jin HH Won HJ Myong SC 2003Am J Hematol2003,74,:1
16Inactivating mutations in NPC1L1 and protection from coronary heart disease显示文摘Myocardial Infarction Genetics Consortium Investigators Stitziel NO Won HH 2014N Engl J Med2014,371,22:1
17A genome-wide association study identifies novel loci associated with susceptibility to chronic myeloid leukemia显示文摘Kim DH Lee ST Won HH 2011Blood2011,117,25:1
18Massively parallel sequencing identifies recurrent mutations in TP53 in thymic carcinoma associated with poor prognosis 显示文摘Moreira AL Won HH McMillan R 2015J Thorac Oncol2015,10,2:1
19A Comprehensive1000 Genomes - based Genome - wide Association Meta -analysis of Coronary Artery Disease 显示文摘Nikpay M Goel A Won HH 2015Nature genetics2015,,47:1
20Predicting national suicide numbers with social media data 显示文摘Won HH Myung W Song GY 2013PloS one2013,8,61:1
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