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| 1 | 中药通光藤治疗食管癌胃癌的临床观察(附112例报告)显示文摘本文报告了中药通光藤制剂治疗112例晚期食管癌和胃癌的临床疗效。结果显示:完全和部分缓解率(CR+PR)为9.8%,微效率(MR)25%,稳定率(SD)52.7%。经该药物治疗后,所有病人的生活质量和免疫力得到改善,吞咽困难和疼痛症状减轻。没有出现血液学、心脏、肝和肾脏毒性。因此,该药物可作为有效的抗癌中药在临床推广应用。 | Wang Zhiliang Wang Guiji Yue Bangyi(Clinical Cooperation Group of Xiaoaiping Of Henan Province, Zhengzhou 450052) | 1995 | 河南肿瘤学杂志1995，8，3： | 14 |
| 2 | Phospholipase C Delta 3 inhibits apoptosis and promotes proliferation,migration,and invasion of thyroid cancer cells via Hippo pathway显示文摘In recent decades,the incidence of thyroid cancer(TC)has rapidly increased,leading us to explore the complex underlying mechanisms.We identified the gene Phospholipase C Delta 3(PLCD3)as a potential oncogene in TC by conducting the whole transcriptome sequencing.Our study is to understand the oncogenic role of PLCD3 in TC.We verified the overexpression of PLCD3 in TC from The Cancer Genome Atlas,Gene Expression Omnibus databases,and a locally validated cohort.Clinical correlation analysis showed that PLCD3 expression was related to histological type,T stage,lymph node metastasis(LNM),and disease stage.The high expression of PLCD3 could be a distinguishing factor for TC and its LNM.The biological function was examined using small interfering RNA-transfected TC cell lines.Silenced PLCD3 could inhibit colony formation,migration,and invasion ability and promote apoptosis of TC cell lines.PLCD3 silencing reversed the epithelial-mesenchymal transition but induced the apoptotic progress.Further exploration revealed that PLCD3 might be associated with critical genes of the Hippo pathway.The expressions of RHOA,YAP1/TAZ,and their downstream targets were decreased significantly when PLCD3 was down-regulated.YAP1 overexpression rescued the tumor-suppressive effect caused by PLCD3 silencing.This study demonstrates that PLCD3 is an oncogene that supports tumorigenesis and progression in TC,and PLCD3 may be a potential target gene for TC treatment. | Lizhi Lin Jialiang Wen Bangyi Lin Hao Chen Adheesh Bhandari Yufeng Qi Danni Zheng Ouchen Wang | 2021 | Acta Biochimica et Biophysica Sinica2021，53，4： | 4 |
| 3 | Optical detection of Prorocentrum donghaiense blooms based on multispectral reflectance显示文摘Prorocentrum donghaiense is one of the most common red tide causative dinoflagellates in the Changjiang(Yangtze)River Estuary and the adjacent area of the East China Sea.It causes large-scale blooms in late spring and early summer that lead to widespread ecologic and economic damage.A means for distinguishing dinoflagellate blooms from diatom(Skeletonema costatum)blooms is desired.On the basis of measurements of remote sensing reflectance[Rrs(λ)]and inherent optical parameters,the potential of using a multispectral approach is assessed for discriminating the algal blooms due to P.donghaiense from those due to S.costatum.The behavior of two reflectance ratios[R1=Rrs(560)/Rrs(532)and R2=Rrs(708)/Rrs(665)],suggests that differentiation of P.donghaiense blooms from diatom bloom types is possible from the current band setup of ocean color sensors.It is found that there are two reflectance ratio regimes that indicate a bloom is dominated by P.donghaiense:(1)R1>1.55 and R2<1.0 or(2)R1>1.75 and R21.0.Various sensitivity analyses are conducted to investigate the effects of the variation in varying levels of chlorophyll concentration and colored dissolved organic matter(CDOM)as well as changes in the backscattering ratio(bbp/bp)on the efficacy of this multispectral approach.Results indicate that the intensity and inherent optical properties of the algal species explain much of the behavior of the two ratios.Although backscattering influences the amplitude of Rrs(λ),especially in the 530 and 560 nm bands,the discrimination between P.donghaiense and diatoms is not significantly affected by the variation of bbp/bp.Since aCDOM(440)in coastal areas of the ECS is typically lower than 1.0 m 1in most situations,the presence of CDOM does not interfere with this discrimination,even as SCDOM varies from 0.01 to 0.026 nm 1.Despite all of these effects,the discrimination of P.donghaiense blooms from diatom blooms based on multispectral measurements of Rrs(λ)is feasible. | TAO Bangyi PAN Delu MAO Zhihua SHEN Yuzhang ZHU Qiankun CHEN Jianyu | 2013 | Acta Oceanologica Sinica2013，32，10： | 3 |
| 4 | The proportions and variations of the light absorption coefficients of major ocean color components in the East China Sea显示文摘The East China Sea (ECS),one of the largest continental seas,has dynamic hydrology and complex optical characteristics that make ocean color remote-sensing retrieval difficult.The distributions and proportions of the light absorption coefficients of major ocean color components based on two large-scale investigations in the ECS are presented,showing these features in typical summer and winter seasons.The absorption coefficient a CDOM,a NAP and a phy of colored dissolved organic matter,non-algal particle,and pigment of phytoplankton show a decreasing trend from the coast to the outer shelf.According to the a CDOM distribution at 440 nm,the Changjiang River plume shows an abnormal southeastward transport.An extremely high a NAP value patch at 440 nm is present in the middle coast.The chlorophyll-a-specific phytoplankton pigment absorption (a phy) is much higher in winter than in summer,which may cause serious underestimated results when applying the averaged a phy into remote-sensing algorithms for chlorophyll concentration retrieval.The importance of phytoplankton size was evident in outer shelf waters.The absorption of a CDOM (440) is a dominant component accounting for over half of the total seawater absorption in summer.The a NAP (440) accounts for 64% of the absorption of the ECS coastal area in winter. | LEI Hui PAN Delu BAI Yan TAO Bangyi SUN Jun ZHANG Lin ZHANG Xuan | 2012 | Acta Oceanologica Sinica2012，31，2： | 3 |
| 5 | A new algorithm based on the background field for red tide monitoring in the East China Sea显示文摘Remote sensing has been proven to be an effective means of monitoring red tides. The spectral information is an important basis for establishing a model to monitor red tides. The spectral curves of red tide events are analyzed and compared with multiyear monthly averaged spectral curves based on MODIS data from July 2002 to June 2012, as well as spectral differences at the same location during red tide presence and absence. A red tide monitoring algorithm is developed based on the background field to extract the red tide information of the East China Sea(ECS). With the application of the algorithm in the ECS, the results reveal that the developed model can effectively determine the location of red tides, with good correspondence to the results from an official bulletin. This demonstrates that the algorithm can effectively extract the red tide information. | XU Xiaohui PAN Delu MAO Zhihua TAO Bangyi | 2014 | Acta Oceanologica Sinica2014，33，5： | 3 |
| 6 | A regional remote sensing algorithm for total suspended matter in the East China Sea显示文摘 | Zhihua Mao Jianyu Chen Delu Pan Bangyi Tao Qiankun Zhu | 2012 | Remote Sensing of Environment2012，，： | 1 |
| 7 | Corrosion resistance of benzotriazole passivated Cu-Zn-Alshape memory alloy in artificial Ringer's solution显示文摘The corrosion resistance of the Cu-Zn-Al shape memory alloy passivated by benzotriazole was investigated bysalt spraying test and electrochemical methods in artificial Ringer’s solution. The results showed that after benzotriazolepassivation, the corrosion resistance of the Cu-Zn-Al shape memory alloy was improved evidently. The anodic polarizationcurrent density of the passivated alloy decreased, the mass loss reduced, the anodic passivation accelerated, the anodic ac-tive dissolution was inhibited effectively, and the surface tarnishing was restrained. Infrared reflection spectrum test showedthat Cu(l)-benzotriazole or Cu(II)-benzotriazole complex layer was formed on the surface of the Cu-Zn-Al shape memoryalloy after passivation. This layer appeared plane, well adhesion, and presented homogeneous golden metallic luster. Thecorrosion resistance of the Cu-Zn-Al shape memory alloy passivated by benzotriazole is improved for the formation of anelectrochemical stable baffle layer on passivated surface. This layer separates the metal substrate from the outside corrosionmedium effectively and retards the corrosion process of dezincification. | LIANG Chenghao CHEN Bangyi CHEN Wan WANG Hua | 2005 | Rare Metals2005，24，3： | 1 |
| 8 | Advances in coastal ocean boundary layer detection technology and equipment in China显示文摘Accurate and comprehensive knowledge of the atmospheric environment and its evolution within the coastal ocean boundary layer are necessary for understanding the sources,chemical mechanisms,and transport processes of air pollution in land,sea,and atmosphere.We present an overview of coastal ocean boundary layer detection technology and equipment in China and summarize the progress and main achievements in recent years.China has developed a series of coastal ocean boundary layer detection technologies,including Light Detection and Ranging(LIDAR),turbulent exchange analyzer,air-sea flux analyzer,stereoscopic remote sensing of air pollutants,and oceanic aerosol detection equipment to address the technical bottleneck caused by harsh environmental conditions in coastal ocean regions.Advances in these technologies and equipment have provided scientific assistance for addressing air pollution issues and understanding land-sea-atmosphere interactions over coastal ocean regions in China.In the future,routine atmospheric observations should cover the coastal ocean boundary layer of China. | Haitao Zheng Youwen Sun Tao Luo Xueling Cheng Shiyong Shao Shouyin Zheng Bangyi Tao Bin Chen Qianguang Tu Kan Huang Bingbing Wang Mian Wang Xiaoquan Song Tianshu Zhang Yin Cheng Jianguo Liu | 2023 | Journal of Environmental Sciences2023，，1： | 0 |
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