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| 1 | The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters显示文摘最近的研究在众多的生物过程增加了我们长 noncoding RNA (lncRNAs ) 的理解,但是很少在体的房间 reprogramming 检验了他们的角色。通过表示介绍并且功能的屏蔽,我们鉴别了大 intergenic noncoding RNA p21 (lincRNA-p21 ) 损害 reprogramming。尤其是, lincRNA-p21 被 p53 导致,但是不在 reprogramming 支持 apoptosis 或房间老朽。相反, lincRNA-p21 与 H3K9 methyltransferase SETDB1 和维护 DNA methyltransferase DNMT1 联系,它被 RNA 有约束力的蛋白质 HNRNPK 便于。因而, lincRNA-p21 由在 pluripotency 基因倡导者支撑 H3K9me3 或 CpG methylation 阻止 reprogramming。我们的结果在 reprogramming 提供卓见进 lncRNAs 的角色并且建立在 p53 和 heterochromatin 规定之间的一个新奇连接。 | Xichen Bao Haitao Wu Xihua Zhu Xiangpeng Guo Andrew P Hutchins Zhiwei Luo Hong Song Yongqiang Chen Keyu Lai Menghui Yin Lingxiao Xu Liang Zhou Jiekai Chen Dongye Wang Baoming Qin Jon Frampton Hung-Fat Tse Duanqing Pei Huating Wang Biliang Zhang Miguel A Esteban | 2015 | Cell Research2015，25，1： | 21 |
| 2 | Optimization of slightly acidic electrolyzed water spray for airborne culturable bacteria reduction in animal housing显示文摘Slightly acidic electrolyzed water(SAEW)spray has been considered as a novel approach for airborne bacteria reduction in animal housing.This study aimed to optimize the operating parameters of SAEW spray based on the size distribution of sprayed aerosols,the available chlorine travelling loss in sprayed aerosols,and the reduction efficiency of airborne culturable bacteria(CB).The optimized operating parameters were the nozzle orifice diameter and the spray pressure.The size distribution characteristics of sprayed SAEW aerosols under different operating parameters were quantified.The pH and available chlorine concentrations of the original SAEW solution and the SAEW aerosols collected at 0 m,0.25 m,0.50 m,0.75 m,and 1.00 m from the spray nozzle head were analyzed.A bioaerosol nebulizing generator was used to simulate animal housing environment in an environmentally-controlled chamber.Six SAEW spray trials under different operating parameters were conducted at a spray dosage of 80 mL/m2 in the chamber.Airborne CB concentrations before and after spray were measured to investigate the reduction efficiency of airborne CB.Dv(50),the volume-based diameter below which 50%of the particle being present,increased with the nozzle orifice diameter and decreased with the spray pressure.The travelling loss of available chlorine in the sprayed SAEW aerosols was greatly dependent on Dv(50).SAEW spray with medium size sprayed aerosols(Dv(50)=86.62μm,67.94μm,and 54.53μm)showed significantly higher airborne CB reduction efficiencies than large(Dv(50)=121.80μm and 96.00μm)or small size aerosols(Dv(50)=42.57μm).The spray operating parameters that provide medium size sprayed aerosols(Dv(50)~60-90μm)are recommended for SAEW spray in animal housing. | Zheng Weichao Ni Li Hui Xue Li Baoming Zhang Jiafa | 2016 | International Journal of Agricultural and Biological Engineering2016，9，4： | 7 |
| 3 | Sustainable utilization of biological resources from coastal wetlands in China显示文摘The main utilization of biological resources from coastal wetlands in China and the major limiting factors on sustainable utilization of these resources are reviewed. Strategies for the sustainable utilization of coastal wetlands are proposed. These include further studies on saline agriculture and wetland ecosystems, optimizing methods for maximizing metabolic production from organisms, developing microbial resources and efficient utilization of biological genetic resources, and exploiting bioenergy from coastal wetlands. | TANG BoPing ZHANG DaiZheng GE BaoMing ZHANG HuaBin | 2013 | Chinese Science Bulletin2013，58，19： | 5 |
| 4 | Transcriptome analysis of the effect of pyrroloquinoline quinone disodium(PQQ·Na2) on reproductive performance in sows during gestation and lactation显示文摘Background: Pyrroloquinoline quinone(PQQ), which is a water soluble, thermo-stable triglyceride-quinone, is widely distributed in nature and characterized as a mammalian vitamin-like redox cofactor. The objective of this study was to investigate the effects of pyrroloquinoline quinone disodium(PQQ·Na2) on reproductive performance in sows.Results: Dietary supplementation with PQQ·Na2 significantly increased the total number of piglets born, the number of piglets born alive and the born alive litter weight. It also increased the antioxidant status in the placenta, plasma and milk. The concentration of NO was significantly increased in the plasma and placenta. RNA-seq analysis showed that462 unigenes were differentially expressed between the control(Con) treatment and PQQ treatment groups.Among these unigenes, 199 were upregulated, while 263 unigenes were downregulated. The assigned functions of the unigenes covered a broad range of GO categories. Reproduction(27, 7.03%) and the reproduction process(27, 7.03%) were assigned to the biological process category. By matching DEGs to the KEGG database, we identified 29 pathways.Conclusions: In conclusion, dietary supplementation with PQQ·Na2 in gestating and lactating sows had positive effects on their reproductive performance. | Boru Zhang Chenxi Wang Wei Yang Hongyun Zhang Qingwei Meng Baoming Shi Anshan Shan | 2019 | Journal of Animal Science and Biotechnology2019，10，4： | 5 |
| 5 | Development of highly glyphosate-tolerant tobacco by coexpression of glyphosate acetyltransferase gat and EPSPS G2-aroA genes显示文摘The widely used herbicide glyphosate targets 5-enolpyruvylshikimate-3-phosphate synthase(EPSPS).Glyphosate acetyltransferase(GAT)effectively detoxifies glyphosate by N-acetylation.With the aim of identifying a new strategy for development of glyphosate-tolerant crops,the plant expression vector pG2-GAT harboring gat and G2-aroA(encoding EPSPS)has been transformed into tobacco(Nicotiana tabacum)to develop novel plants with higher tolerance to glyphosate.Results from Southern and Western blotting analyses indicated that the target genes were integrated into tobacco chromosomes and expressed effectively at the protein level.Glyphosate tolerance was compared among transgenic tobacco plants containing gat,G2-aroA,or both genes.Plants containing both gat and G2-aroA genes were the most glyphosate-tolerant.This study has shown that a combination of different strategies may result in higher tolerance in transgenic crops,providing a new approach for development of glyphosate-tolerant crops. | Baoqing Dun Xujing Wang Wei Lu Ming Chen Wei Zhang Shuzhen Ping Zhixing Wang Baoming Zhang Min Lin | 2014 | The Crop Journal2014，2，Z1： | 4 |
| 6 | Nonbinary LDPC cycle codes: efficient search,design, and code optimization显示文摘Nonbinary low-density parity-check (NBLDPC)codes have the ability of approaching capacitywhen decoded iteratively using a probabilistic de-coding algorithm. With the increase of the finitefield size q, NBLDPC codes over GF(q) have muchbetter performance under iterative decoding fora constant code length. | Hengzhou XU Chao CHEN Min ZHU Baoming BAI Bo ZHANG | 2018 | Science China(Information Sciences)2018，61，8： | 3 |
| 7 | Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells显示文摘 | Miguel Angel Esteban Tao Wang Baoming Qin Jiayin Yang Dajiang Qin Jinglei Cai Wen Li Zhihui Weng Jiekai Chen Su Ni Keshi Chen Yuan Li Xiaopeng Liu Jianyong Xu Shiqiang Zhang Feng Li Wenzhi He Krystyna Labuda Yancheng Song Anja Peterbauer Susanne Wolbank H | 2010 | Cell Stem Cell2010，，： | 3 |
| 8 | Experimental Research on the Mechanism of Lift Amplification and Vibration Suppression of Lorentz Force显示文摘The Lorentz force generated by electromagnetic field on the surface of the cylinder in the electrolyte solution may modify the structure of the flow boundary layer effectively. The transient control process of Lorentz force is investigated experimentally for lift amplification and vibration suppression. The experiments are conducted in a rotating annular tank filled with a low-conducting electrolyte. A cylinder with an electro-magnetic actuator is placed into the electrolyte. The lift force of cylinder is measured using the strain gages attached to a fixed beam, and the flow fields are visualized by the dye markers. The results show that the upper vortex on the cylinder is suppressed, and the wake becomes a line and leans to the lower side under the action of upside Lorentz force while the lower vortex on the cylinder is suppressed and limited in a small region. Therefore, the value of lift increases with the variation of flow field. However, the vortexes on the cylinder are suppressed fully under the action of symmetrical Lorentz force which leads to the suppression of lift oscillation and then the vibration of cylinder are suppressed fully. | ZHANG Hui FAN Baochun CHEN Zhihua LI Hongzhi LI Baoming | 2013 | Defence Technology(防务技术)2013，9，2： | 2 |
| 9 | Calibration of Mars Energetic Particle Analyzer (MEPA)显示文摘The first Mars exploration mission of China(Tianwen-1)is scheduled to be launched in 2020;a charged particle telescope,the Mars Energetic Particle Analyzer(MEPA),is carried as one of the payloads on the orbiter.The MEPA is designed to measure solar energetic particles(SEPs)and galactic cosmic rays(GCRs)in the near-Mars space and in the transfer orbit from Earth to Mars.Before the launch,the MEPA was calibrated in ground experiments with radioactive sources,electronic pulses,and accelerator beams.The calibration parameters,such as energy conversion constants,threshold values for the triggers,and particle identification criteria,were determined and have been stored for onboard use.The validity of the calibration parameters has been verified with radioactive sources and beams.The calibration results indicate that the MEPA can measure charged particles reliably,as designed,and that it can satisfy the requirements of the Tianwen-1 mission. | ShuWen Tang Yi Wang HongYun Zhao Fang Fang Yi Qian YongJie Zhang HaiBo Yang CunHui Li Qiang Fu Jie Kong XiangYu Hu Hong Su ZhiYu Sun YuHong Yu BaoMing Zhang Yu Sun ZhiPeng Sun | 2020 | Earth and Planetary Physics2020，4，4： | 2 |
| 10 | RECENT DEVELOPMENT OF ERROR CONTROL CODES FOR FUTURE COMMUNICATION AND STORAGE SYSTEMS显示文摘The outstanding performance of error control codes has attracted the interest of the information and communications theory community and industry partners for more than 20 years since Turbo codes were invented.In recent years,there are more and more scenarios in modern communication and digital storage systems,such as wireless communications,optical communications,fl ash memories,computer hard drives,sensor networks, | zesong fei jinhong yuan ming xiao baoming bai shengli zhang dengsheng lin | 2017 | China Communications2017，14，8： | 2 |
| 11 | Application of tobacco stems briquetting in tobacco flue-curing in rural area of China显示文摘To reduce the conventional energy consumption in rural area of China,tobacco stems briquetting(TSB)was used as fuel during the process of tobacco flue-curing,compared with honeycomb briquette(HB).Three fire furnaces with different heat exchangers using TSB were compared using the tobacco flue-curing.The results showed that the smog temperature of TSB was higher than that of HB,the efficiency of bio-fuel system with TSB was from 43.5%to 54%,while the efficiency of traditional fuel system was 51.5%.And the cost of tobacco flue-curing per hectare with TSB and HB was$750.0 and$1282.5,respectively.It is proved that TSB is an alternative choice using for the industry of tobacco flue-curing,and the improvement in the structure of fire furnace could optimize the process of tobacco flue-curing. | Wang Xinfeng Xu Guizhuan Zhang Bailiang Jiao Youzhou Lu Haifeng Li Baoming | 2015 | International Journal of Agricultural and Biological Engineering2015，8，6： | 2 |
| 12 | Heat stress alleviation for dairy cows housed in an open-sided barn by cooling fan and perforated air ducting(PAD)system显示文摘Curtain-sided barns with circulation fans above stall are commonly used to house dairy cows in China.Many farms equipped with circulation fans are unable to provide appropriate cooling,especially for the naturally ventilated shed,which can result in decreasing feed intake and milk production.For alleviating heat stress and improving animal comfort,a system consisting of an air cooler and a 30 m perforated air duct(PAD)was integrated to evenly distribute cooling air.The air was cooled by underground water and delivered to targeted zones above stall bed.The system was evaluated in an open sided dairy barn in Tianjin,China.For the stalls equipped with PAD system,air velocity reached above 1.1 m/s at 0.5 m height plane of the stall space,and was more uniformly distributed.Compared to the stalls equipped with circulation fans,the PAD system lowered air temperature by 1.5℃,and increased relative humidity by 8.1%.On average,Temperature Humidity Index(THI)and Equivalent Temperature Index(ETI)were decreased by 0.5 and 0.6,respectively.After a 15 days’operation of the system,rectal temperatures of the treated dairy cows were significantly lowered.The results also showed that the cows under PADs had a higher milk production.These findings suggest the PAD can be an effective cooling alternative for naturally ventilated dairy barns to alleviate heat stress. | Xie Lina Wang Chaoyuan Ding Luyu Gui Zhiyuan Zhang Lu Shi Zhengxiang Li Baoming Jia Chuntao | 2017 | International Journal of Agricultural and Biological Engineering2017，10，6： | 2 |
| 13 | Unimodal productivity-biodiversity relationship along the gradient of multidimensional resources across Chinese grasslands显示文摘Resources can affect plant productivity and biodiversity simultaneously and thus are key drivers of their relationships in addition to plant-plant interactions.However,most previous studies only focused on a single resource while negle cting the nature of resource multidimensionality.Here we integrated four essential resources for plant growth into a single metric of resource diversity(RD)to investigate its effects on the productivity-biodiversity relationship(PBR)across Chinese grasslands.Results showed that habitats differing in RD have different PBRs—positive in low-resource habitats,but neutral in medium-and high-resource ones—while collectively,a weak positive PBR was observe d.However,when excluding direct effects of RD on productivity and biodiversity,the PBR in high-resource habitats became negative,which leads to a unimodal instead of a positive PBR along the RD gradient.By integrating resource effects and changing plant-plant interactions into a unified framework with the RD gradient,our work contributes to uncovering underlying me chanisms for inconsistent PBRs at large scales. | Yanfen Wang Jianqing Du Zhe Pang Yali Liu Kai Xue Yann Hautier Biao Zhang Li Tang Lili Jiang Baoming Ji Xingliang Xu Jing Zhang Ronghai Hu Shutong Zhou Fang Wang Rongxiao Che Di Wang Chaoting Zhou Xiaoyong Cui Nico Eisenhauer Yanbin Hao | 2022 | National Science Review2022，9，12： | 2 |
| 14 | Biocrude oil production from Chlorella sp.cultivated in anaerobic digestate after UF membrane treatment显示文摘Algae cultivation in animal wastewater could recover nutrient resources,and harvest considerable amount of algae biomass for biofuel conversion.In this study,Chlorella sp.cultivated in ultrafiltration(UF)membrane treated anaerobic digestion effluent of chicken manure was converted into biocrude oil through hydrothermal liquefaction(HTL).The potential of biocrude production from grown Chlorella sp.was studied through changing the operational conditions of HTL,i.e.,holding temperature(HT,250℃-330℃),retention time(RT,0.5-1.5 h),and total solid(TS)(15 wt%-25 wt%)of the feedstock.The highest biocrude oil yield was 32.9%at 330℃,1.5 h and 20 wt%TS.The single factor experiments of HT also suggested that the biocrude oil yield decreased when the temperature was higher than 330℃.There were no significant differences of elemental contents in biocrude samples.The maximum higher heating values(HHV)of Chlorella sp.biocrude was 40.04 MJ/kg at HT of 330℃,RT of 1 h and TS of 15 wt%.This study suggests the great potential for energy recovery from Chlorella sp.cultivated in UF membrane treated anaerobic digestion effluent via HTL. | Wang Meng Wang Xinfeng Zhu Zhangbing Lu Jianwen Yuanhui Zhang Li Baoming Lu Haifeng Duan Na Zhang Dongming Dong Taili Liu Zhidan | 2017 | International Journal of Agricultural and Biological Engineering2017，10，1： | 1 |
| 15 | Nitrogen and phosphorous adsorption from post-hydrothermal liquefaction wastewater using three types of zeolites显示文摘Hydrothermal liquefaction(HTL)has been studied as a promising technology for converting wet biomass into bio-crude oil and the nutrient-rich post-hydrothermal liquefaction wastewater(PHWW)could be reused for algae and bacteria production.However,the PHWW from HTL contains various types of contaminants that need to be removed before reuse.Too high nutrients(nitrogen and phosphorous)contents,such as ammonium,are inhibitive to algal growth and bacteria species in anaerobic process.It is desirable to reduce nutrients concentration in PHWW to an acceptable level using zeolite adsorption.This study investigated nitrogen and phosphorous adsorption efficiencies from PHWW using three types of zeolites:activated clinoptilolite,natural clinoptilolite and Na-modified zeolite.Effects of ions and pH in the adsorption process were also investigated.Results showed that three zeolite variables affecting ammonium adsorption process could be ranked as follows:zeolite dosage>type>particle size,via an orthogonal experiment design.Activated clinoptilolite,with a particle size of 0.18-0.30 mm and a dosage of 0.4 g/mL demonstrated the highest ammonium adsorption efficiency of 54.92%.Zeolite could also adsorb organic nitrogen and had a high adsorption efficiency of phosphorous(97.85%).This study showed that zeolite is effective to adsorb nutrients in PHWW.The adsorption treated PHWW can then be used for culturing algae or anaerobic treatment,and the adsorbed nutrients can be reused later. | Ran Xia Duan Na Yuanhui Zhang Li Baoming Liu Zhidan Lu Haifeng | 2015 | International Journal of Agricultural and Biological Engineering2015，8，5： | 1 |
| 16 | Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells显示文摘 | Miguel Angel Esteban Tao Wang Baoming Qin Jiayin Yang Dajiang Qin Jinglei Cai Wen Li Zhihui Weng Jiekai Chen Su Ni Keshi Chen Yuan Li Xiaopeng Liu Jianyong Xu Shiqiang Zhang Feng Li Wenzhi He Krystyna Labuda Yancheng Song Anja Peterbauer Susanne Wolbank H | 2010 | Cell Stem Cell2010，，1： | 1 |
| 17 | Modeling and simulation of passenger alighting and boarding movement in Beijing metro stations显示文摘 | Zhang Qi Han Baoming Li Dewei | 2008 | Transporta- tion Research Part C2008，，16： | 1 |
| 18 | Cucurmosin induces the apoptosis of human pancreatic cancer CFPAC-1 cells by inactivating the PDGFR-b signalling pathway显示文摘 | Jieming Xie Congfei Wang Baoming Zhang | 2013 | Pharmacological Reports2013，65，： | 1 |
| 19 | Delay adjust- ment method at transfer station of high - speed railway 显示文摘 | LI Xiaojuan HAN Baoming ZHANG Qi | 2013 | Advances in Mechanical Engineering2013，，5： | 1 |
| 20 | Simulation study of transverse flux linear switched reluctance drive显示文摘 | Ge Baoming Zhang Yihuang Yu Xuehai Nan Yonghui | 2005 | ICEMS20052005，1，： | 1 |
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