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| 1 | A complete sequence and comparative analysis of a SARS-associated virus(Isolate BJ01)显示文摘The genome sequence of the Severe Acute Respiratory Syndrome (SARS)-associated virus provides essential information for the identification of pathogen(s), exploration of etiology and evolution, interpretation of transmission and pathogenesis, development of diagnostics, prevention by future vaccination, and treatment by developing new drugs. We report the complete genome sequence and comparative analysis of an isolate (BJ01) of the coronavirus that has been recognized as a pathogen for SARS. The genome is 29725 nt in size and has 11 ORFs (Open Reading Frames). It is composed of a stable region encoding an RNA-dependent RNA polymerase (composed of 2 ORFs) and a variable region representing 4 CDSs (coding sequences) for viral structural genes (the S, E, M, N proteins) and 5 PUPs (putative uncharacterized proteins). Its gene order is identical to that of other known coronaviruses. The sequence alignment with all known RNA viruses places this virus as a member in the family of Coronaviridae. Thirty putative substitutions have been identified by comparative analysis of the 5 SARS- associated virus genome sequences in GenBank. Fifteen of them lead to possible amino acid changes (non-synonymous mutations) in the proteins. Three amino acid changes, with predicted alteration of physical and chemical features, have been detected in the S protein that is postulated to beinvolved in the immunoreactions between the virus and its host. Two amino acid changes have been detected in the Mprotein, which could be related to viral envelope formation. Phylogenetic analysis suggests the possibility of non-human origin of the SARS-associated viruses but provides noevidence that they are man-made. Further efforts should focus on identifying the etiology of the SARS-associated virus and ruling out conclusively the existence of otherpossible SARS-related pathogen(s). | QIN E'de ZHU Qingyu YU Man FAN Baochang CHANG Guohui SI Bingyin YANG Bao PENG Wenming JIANG Tao LIU Bohua DENG Yongqiang LIU Hong ZHANG Yu WANG Cui LI Yuquan GAN Yonghua LI Xiaoyu L Fushuang TAN Gang CAO Wuchun, YANG Ruifu Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China WANG Jian, LI Wei, XU Zuyuan, LI Yan, WU Qingfa, LIN Wei, CHEN Weijun, TANG Lin, DENG Yajun, HAN Yujun, LI Changfeng, LEI Meng, LI Guoqing, LI Wenjie, L Hong, SHI Jianping, TONG Zongzhong, ZHANG Feng, LI Songgang, LIU Bin, LIU Siqi, DONG Wei, WANG Jun, Gane K-S Wong, YU Jun & YANG Huanming* Beijing Genomics Institute, Chinese Academy of Sciences, Beijing 101300 National Center for Genome Information, Beijing 101300, China | 2003 | Chinese Science Bulletin2003，48，10： | 121 |
| 2 | Preliminary Scientific Results of Chang'E-1 Lunar Orbiter:Based on Payloads Detection Data in the First Phase显示文摘Chang'E-1 lunar Orbiter was launched by Long March 3A rocket from Xichang Satel-lite Launch Center at 18:05BT(Beijing Time) Oct.24,2007.It is the first step of its ambitious three-stage moon program,a new milestone in the Chinese space exploration history.The primary science objectives of Chang'E-1 lunar orbiter are to obtain three-Dimension(3D) stereo images of the lunar surface,to analyze the distribution and abundance of elements on the surface,to investigate the thickness of lunar soil,evaluate helium-3 resources and other characteristics,and to detect the space environment around the moon.To achieve the above four mission objectives,eight sets of scientific instruments are chosen as the payloads of the lunar orbiter,including a CCD stereo camera(CCD),a Sagnac-based interferometer spectrometer(ⅡM),a Laser Altimeter(LAM),a Microwave Radiometer(MRM),a Gamma-Ray Spectrometer(GRS),an X-ray spectrometer(XRS),a High-Energy Particle Detector(HPD),and two Solar Wind Ion Detectors(SWID).The detected data of the payloads show that all payloads work well.This paper introduces the status of payloads in the first phase and preliminary scientific results. | OUYANG Ziyuan JIANG Jingshan LI Chunlai SUN Huixian ZOU Yongliao LIU Jianzhong LIU Jianjun ZHAO Baochang REN Xin YANG Jianfeng ZHANG Wenxi WANG Jianyu MOU Lingli CHANG Jin ZHANG Liyan WANG Huanyu LI Yongquan ZHANG Xiaohui ZHENG Yongchun WANG Shijin BIAN Wei | 2008 | 空间科学学报2008，28，5： | 24 |
| 3 | Multi-block SSD based on small object detection for UAV railway scene surveillance显示文摘A method of multi-block Single Shot Multi Box Detector(SSD)based on small object detection is proposed to the railway scene of unmanned aerial vehicle surveillance.To address the limitation of small object detection,a multi-block SSD mechanism,which consists of three steps,is designed.First,the original input images are segmented into several overlapped patches.Second,each patch is separately fed into an SSD to detect the objects.Third,the patches are merged together through two stages.In the first stage,the truncated object of the sub-layer detection result is spliced.In the second stage,a sub-layer suppression and filtering algorithm applying the concept of non-maximum suppression is utilized to remove the overlapped boxes of sub-layers.The boxes that are not detected in the main-layer are retained.In addition,no sufficient labeled training samples of railway circumstance are available,thereby hindering the deployment of SSD.A two-stage training strategy leveraging to transfer learning is adopted to solve this issue.The deep learning model is preliminarily trained using labeled data of numerous auxiliaries,and then it is refined using only a few samples of railway scene.A railway spot in China,which is easily damaged by landslides,is investigated as a case study.Experimental results show that the proposed multi-block SSD method produces an overall accuracy of 96.6%and obtains an improvement of up to 9.2%compared with the traditional SSD. | Yundong LI Han DONG Hongguang LI Xueyan ZHANG Baochang ZHANG Zhifeng XIAO | 2020 | Chinese Journal of Aeronautics2020，33，6： | 19 |
| 4 | A retrospective comparison of the modified tension band technique and the parallel titanium cannulated lag screw technique in transverse patella fracture显示文摘 | Wang Chengxue Tan Lei Qi Baochang Hou Xiangfeng Huang Yulong Zhang Haipeng Yu Tiecheng | 2014 | Chinese Journal of Traumatology2014，17，4： | 14 |
| 5 | Chang'E-1 Lunar Mission:An Overview and Primary Science Results显示文摘Chang'E-1 is the first lunar mission in China,which was successfully launched on Oct.24th,2007.It was guided to crash on the Moon on March 1,2009,at 52.36°E,1.50°S,in the north of Mare Fecunditatis.The total mission lasted 495 days,exceeding the designed life-span about four months.1.37Terabytes raw data was received from Chang'E-1.It was then processed into 4Terabytes science data at different levels.A series of science results have been achieved by analyzing and applicating these data,especially 'global image of the Moon of China's first lunar exploration mission'.Four scientific goals of Chang'E-1 have been achieved.It provides abundant materials for the research of lunar sciences and cosmochemistry.Meanwhile these results will serve for China's future lunar missions. | Ouyang Ziyuan Li Chunlai Lu Chang Liu Jianzhong Zou Yongliao Zhang Hongbo Jianjun Zuo Wei Su Yah Wen Weibin Bian Wei Zhao Baochang Wang Jianyu Yang Jianfeng Chang Jin Wang Huanyu Zhang Xiaohui Wang Shijin Wang Min Ren Xin Mu Lingli Kong Deqing Wang Xiaoqian Wang Fang Geng Liang Zhang Zhoubin Zheng Lei Zhu Xinying Zheng Yongchun Li Junduo Zou Xiaoduan Xu Chun Shi Shuobiao Gao Yifei Gao Guannan | 2010 | 空间科学学报2010，30，5： | 11 |
| 6 | Effects of sediment physical properties on the phosphorus release in aquatic environment显示文摘Particle size, porosity, and the initial phosphorus concentration in sediments are the main factors affecting phosphorus release flux through the sediment-water interface. Sediments can be physically divided to muddy and sandy matters, and the adsorption-desorption capacity of sediment with phosphorus depends on particle size. According to phosphorus adsorption-desorption experiments, phosphorus sorption capacity of the sediment decreases with the increase of particle dimension. But among the size-similar particles, sediment with a bigger particle size has the larger initial phosphorus release rate. In terms of muddy and sandy sediments, there are inversely proportional relationships between the release rate and the flux. Due to the contact of surface sediment and the overlying water, the release flux from the sediment is either from direct desorption of surface sediment layer or from the diffusion of pore water in the sediment layer, which is mainly determined by sediment particle size and porosity. Generally, static phosphorus release process may include two stages: the first is the initial release. As for coarse particles, phosphorus is desorbed from surface sediment. And for fine particles, phosphorus concentration in water often decreases, mainly from pore water by the molecular diffusion. During the second stage, pore water flows faster in coarse sediment, and phosphorus is easy to desorb from the surface of the particles as diffusion dominates. For the smaller liquid-solid ratio of fine particles and the larger amount of phosphorus adsorption, the release flux from pore water due to diffusion is very small with longer sorption duration. | ZHU HongWei WANG DaoZeng CHENG PengDa FAN JingYu ZHONG BaoChang | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，2： | 8 |
| 7 | Overall scheme and on-orbit images of Chang’E-2 lunar satellite CCD stereo camera显示文摘The goals of engineering and scientific missions for Chang’E-2 lunar satellite require high detection sensitivity and large im-aging dynamic range for the onboard CCD cameras.The TDI CCD image sensor was adopted for the two linear CCD stereo cameras for the first time in the lunar reconnaissance of the world.The design argumentation is described in this paper.The analysis shows that the imagers meet the mission requirements.The satellite was launched on 1 October 2010 at zero window.The cameras obtained images of 7 m resolution on the 100 km orbit for the first time on 24 October 2010,and operated once again on 27 October 2010 to take stereo images of the Sinus Iridum with the resolution better than 1.5 m.On the near-moon-arc of 15 km×100 km elliptical orbit,the images are very clear and rich of grey scales,indicating successful com-pletion of the Chang’E-2 engineering mission.At the present the cameras are acquiring the full lunar surface stereo images with 7 m resolution on the 100 km circular orbit to complete their scientific mission. | ZHAO BaoChang YANG JianFeng WEN DeSheng GAO Wei CHANG LingYing SONG ZongXi XUE Bin ZHAO Wei | 2011 | Science China(Technological Sciences)2011，54，9： | 7 |
| 8 | Stable high-level expression of truncated human papillomavirus type 16 L1 protein in Drosophila Schneider-2 cells显示文摘为了改进存在人的乳头状瘤病毒,打 16 (HPV16 ) 像病毒的粒子(VLP ) 准备,果蝇 inducible/secreted 表示系统,一个高度有效的、节俭的方法,被用来生产 HPV16 VLP。果蝇 Schneider-2 房间是有包含没有原子核本地化顺序和选择向量 pCoHygro plasmids,在 4:1 的比率编码 HPV16L1 蛋白质的目标基因的 pMT/BiP/V5-His 表示向量的 cotransfected。stabled hygromycin 抵抗的房间线 1 个月以后被获得,并且蛋白质表示被铜硫酸盐导致。表示 HPV16L1 蛋白质的分子的团是 66 kDa,作为由 SDS 页揭示了,并且由西方的污点分析证实了。HPV16L1 蛋白质的收益每 1 湩攠灸敲獳潩 ? 敬敶是 0.554 mg 吗? | Jin Zheng Xiaofeng Yang Ying Sun Baochang Lai Yili Wang | 2008 | Acta Biochimica et Biophysica Sinica2008，40，5： | 6 |
| 9 | Parameter estimation of moving targets in the SAR system with a low PRF sampling rate显示文摘In the synthetic aperture radar(SAR)system with low pulse repetition frequency(PRF)sampling,it is difficult for the motion parameters estimation of the moving targets,because of the Doppler spectrum ambiguity and Doppler centroid frequency ambiguity of the echo signals.Considering that moving targets are sparsely distributed in the observed scene,their positions and velocities can be reconstructed by using the compressed sensing(CS)technique.In this paper,the range-walk correction are implemented by the Keystone transform and the sparse range-walk correction(SRWC),then the CS technique is proposed to reconstruct motion parameters by processing the azimuth signals of the moving targets.Experiments using the simulated and real data are performed,and the results confirm the validity of the proposed method. | LIU Yan WU QiSong SUN GuangCai XING MengDao LIU BaoChang BAO Zheng | 2012 | Science China(Information Sciences)2012，55，2： | 5 |
| 10 | Polycrystalline diamond compact with enhanced thermal stability显示文摘Polycrystalline diamond compacts(PDC), which are composed of diamond and WC/Co substrate, and synthesized at high pressure and high temperature(HPHT), are widely applied as the tooth of drilling bit. However, the thermal stability of PDC will be reduced when diamond transforms into graphite due to cobalt in PDC acting as a catalyst during the drilling work. In this study, a new three-layer structured PDC with enhanced thermal stability has been successfully synthesized at pressures of 5.5–7.0 GPa and temperatures of 1650–1750?C. In this structure, the diamond-Si C composite acts as the working layer,and the diamond-Si C-Co composite and WC/Co cements are as the intermediate layer and substrate,respectively. It is found that the initial oxidizing temperature of the three-layered PDC is enhanced up to820?C, which is significantly higher than that(~780?C) of the conventional PDC counterpart. | Shiqi Liu Lei Han Yongtao Zou Pinwen Zhu Baochang Liu | 2017 | Journal of Materials Science & Technology2017，33，11： | 5 |
| 11 | Application of digital pattern-less molding technology to produce art casting显示文摘Compared with the conventional casting process, digital pattern-less casting technology has many advantages such as good machining accuracy, a short processing cycle, and low production cost. It is a new rapid manufacturing technology for castings, integrated with CAD/CAM, casting, CNC machining and many other advanced technologies. With this digital casting technology, no pattern is needed for making molds; it is precise, f lexible, and green. Usually, art castings have complex structures and are made in small batches or even made in a single-piece, especially for large-sized art castings. So it has the shortcomings of high cost, low eff iciency and long time for making a pattern to produce art castings with the conventional casting processes. However, the digital pattern-less casting technology can be applied to fabricate art castings, since it can greatly shorten the manufacturing cycle and lower the production cost, thus having a very good prospect. In this study, based on the digital pattern-less casting technology, a plaque casting with artistic Chinese characters(a Chinese poem) was designed and manufactured, and the production process was demonstrated in detail. | Chen Li Zhang Wei Wu Chenhong Jia Baochang Xiang Qingchun Qiu Keqiang Li Rongde | 2014 | China Foundry2014，11，6： | 5 |
| 12 | Influence of Voids on the Tensile Performance of Carbon/epoxy Fabric Laminates显示文摘This paper aims at investigating the effect of voids on the tensile properties of [(±45)4/(0,90)/(±45)2] S and [(±45)/0 4/(±45)(0,90)] S composites.Specimens with void contents in the range of 0.4% to 9.0% were fabricated from carbon/epoxy fabric.The void content was determined by ultrasonic attenuation and optical image analysis,and microscopic inspection was also used to analyze the shape and size of the voids.The influence of voids on the tensile strength and modulus of both stacking sequence is compared in terms of the size and the shape of the voids.The effect of voids on the initiation and propagation of tensile failure of both stacking sequence composite was investigated. | Hongyan Zhu Baochang Wu Dihong Li Dongxing Zhang Yuyong Chen | 2011 | Journal of Materials Science & Technology2011，27，1： | 5 |
| 13 | The mechanisms of contaminants release due to incipient motion at sediment-water interface显示文摘Sediments in many rivers and lakes are subjected to resuspension due to a combination of hydrodynamics.However,the roles of contaminant-contained dissolved and particulate sediments during the resuspension release are rarely studied.This study focuses on the release quantity of contaminants in both water phase and solid phase.Conservative tracer(NaCl)and reactive tracer(Phosphorus)were respectively added to cohesive fine-grained sediments and non-cohesive coarse-grained sediments.A range of typical shear stress was conducted to characterize the time-depended release of contaminants in a laboratory flume.When the sediment started to move,the concentration of contaminant in the overlying water increased with the bed shear stress,but the dissolved contaminants responded faster than the particulate ones.The observed contaminant release process can be divided into three main stages:the initial two hours fast mixing:the release contribution of pore water could reach up to 75%;the middle 4–6 h adsorption:the partitioning coefficient of contaminant between water phase and solid phase decreased over the time,and the adsorption of contaminates from resuspended sediment dominated the negative release;the last equilibrium stage:the desorption and adsorption reached equilibrium,and the reactive contaminant made an impact on the water quality in the solid phase.The existing formulas to evaluate the release flux are far from practice meaning as the sediment contaminants undergo a very complex release process. | ZHU HongWei CHENG PengDa ZHONG BaoChang WANG DaoZeng | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，8： | 4 |
| 14 | Auto-compensation of velocity-height ratio for Chang’E-2 satellite CCD stereo camera显示文摘The TDI-CCD imaging method using auto-compensation of velocity-height ratio (VHR) was applied to Chang’E-2 satellite CCD stereo camera.Factors that influence the image quality of the camera were discussed,among which the mismatch error in VHR was found to be the main cause.An auto-compensation scheme for VHR was developed.The validity and effectiveness were proved by the on-orbit high quality images. | XUE Bin ZHAO BaoChang YANG JianFeng GAO Weit QIAO WeiDong MA XiaoLong ZHANG Bo LIU JiaHang ZHAO Wei JING Juan Juan | 2011 | Science China(Technological Sciences)2011，54，9： | 4 |
| 15 | Introduction to the Payloads and the Initial Observation Results of Chang'E-1显示文摘Chang'E-1,the orbiter circling the moon 200km above the moon surface,is the first Chinese Lunar exploration satellite.The satellite was successfully launched on 24th October 2007.There are 8 kinds of scientific payloads onboard,including the stereo camera,the laser altimeter,the Sagnac-based interferometer image spectrometer,the Gamma ray spectrometer,the X-ray spectrom-eter,the microwave radiometer,the high energy particle detector,the solar wind plasma detector and a supporting payload data management system.Chang'E-1 opened her eyes to look at the moon and took the first batch of lunar pictures after her stereo camera was switched on in 20th November 2007.Henceforth all the instruments are successfully switched on one by one.After a period of parameter adjustment and initial check out,all scientific instruments are now in their normal operating phase.In this paper,the payloads and the initial observation results are introduced. | SUN Huixian WU Ji DAI Shuwu ZHAO Baochang SHU Rong CHANG Jin WANG Huanyu ZHANG Xiaohui REN Qiongying CHEN Xiaomin OUYANG Ziyuan ZOU Yongliao | 2008 | 空间科学学报2008，28，5： | 4 |
| 16 | Identification and differentiation of major components in three different “Sheng-ma” crude drug species by UPLC/Q-TOF-MS显示文摘Cimicifugae Rhizoma(Sheng ma) is a Ranunculaceae herb belonging to a composite family and well known in China,has been widely used in traditional Chinese medicine.The Pharmacopoeia of the People's Republic of China contains three varieties(Cimicifuga dahurica(Turcz.),Cimicifuga foetida L.and Cimicifuga heracleifolia Kom.) which have been used clinically as 'Sheng-ma'.However,the chemical constituents of three components of 'Sheng-ma' have never been documented.In this study,a rapid method for the analysis of the main components of 'Sheng-ma' was developed using ultra-high performance liquid chromatography with quadrupole-time-of-flight mass spectrometry(UPLC/Q-TOF-MS).The present study reveals the major common and distinct chemical constituents of C.dahurica,C.foetida and C.heracleifolia and also reports principal component and statistical analyses of these results.The components were identified by comparing the retention time,accurate mass,mass spectrometric fragmentation characteristic ions and matching empirical molecular formula with that of the published compounds.A total of 32 common components and 8 markers for different 'Sheng-ma' components were identified.These findings provide an important basis for the further study and clinical utilities of the three 'Sheng-ma' varieties. | Mengxue Fan Kunming Qin Fei Ding Yuting Huang Xiaoli Wang Baochang Cai | 2017 | Acta Pharmaceutica Sinica B2017，7，2： | 4 |
| 17 | Transport mechanisms of contaminants released from fine sediment in rivers显示文摘Contaminants released from sediment into rivers are one of the main problems to study in environmental hydrodynamics. For contaminants released into the overlying water under different hydrodynamic conditions, the mechanical mechanisms involved can be roughly divided into convective diffusion, molecular diffusion, and adsorption/desorption. Because of the obvious environmental influence of fine sediment( D90 = 0.06 mm), non-cohesive fine sediment, and cohesive fine sediment are researched in this paper, and phosphorus is chosen for a typical adsorption of a contaminant. Through theoretical analysis of the contaminant release process, according to different hydraulic conditions, the contaminant release coupling mathematical model can be established by the N–S equation, the Darcy equation,the solute transport equation, and the adsorption/desorption equation. Then, the experiments are completed in an open water flume. The simulation results and experimental results show that convective diffusion dominates the contaminant release both in non-cohesive and cohesive fine sediment after their suspension, and that they contribute more than 90 % of the total release. Molecular diffusion and desorption have more of a contribution for contaminant release from unsuspended sediment. In unsuspension sediment, convective diffusion is about 10–50 times larger than molecular diffusion during the initial stages under high velocity; it is close to molecular diffusion in the later stages. Convective diffusion is about 6 times larger than molecular diffusion during theinitial stages under low velocity, it is about a quarter of molecular diffusion in later stages, and has a similar level with desorption/adsorption. In unsuspended sediment, a seepage boundary layer exists below the water–sediment interface,and various release mechanisms in that layer mostly dominate the contaminant release process. In non-cohesive fine sediment, the depth of that layer increases linearly with shear stress. In cohesive fine sediment, the range seepage boundary is different from that in non-cohesive sediment, and that phenomenon is more obvious under a lower shear stress. | Pengda Cheng Hongwei Zhu Baochang Zhong Daozeng Wang | 2015 | Acta Mechanica Sinica2015，31，6： | 3 |
| 18 | Chemical Synthesis of Proteins Containing 300 Amino Acids显示文摘Chemical synthesis of proteins containing up to 300 amino acids may cover 30%—50%of all the proteins encountered in biomedical studies and may provide an alternate approach to the usually used recombinant expression teclmology,vastly expanding the chemical space of the latter.In the present review article,we tried to survey the recent progresses made for more rapid synthesis of increasingly long peptides and more efficient ligation of multiple peptide segments.The developments of seminal methods by many research groups have greatly contributed to the recent breakthroughs in the successful total synthesis of a number of functionally important proteins,such as oligoubiquitins,bacterial GroEL/ES chaperones,and mirror-image DNA polymerases.Through these studies,a potential bottleneck has also been recognized for the chemical synthesis of large proteins,namely,how to ensure that each peptide segment from a large protein avoids unfavorable aggregation when dissolved in aqueous solution.Many new methods,such as removable backbone modification(RBM)strategy have been developed to overcome this bottleneck,while more studies need to be carried out to develop more effective and less costly methods that ultimately,may lead to fully automatable chemical synthesis of customized proteins of 300 amino acids bearing any artificial designs. | ZHANG Baochang LI Yulei SHI Weiwei WANG Tongyue ZHANG Feng LIU Lei | 2020 | Chemical Research in Chinese Universities2020，36，5： | 3 |
| 19 | Simultaneous chromatographic fingerprinting and quantitative analysis of flavonoids in Pollen Typhae by high-performance capillary electrophoresis显示文摘To evaluate the quality of Pollen Typhae as used in traditional Chinese medicine,a high-performance capillary electrophoresis(HPCE)method has been developed,validated and applied to chromatographic fingerprinting and quantitation of its eight main bioactive flavonoids(naringenin,isorhamnetin 3-0-(2^(G)-α-L-rhamnosy)-rutinoside,rhamnetin 3-0-neohesperidoside,isorhamnetin,quercetin 3-0-(2^(G)-α-L-rhamnosyl)-rutinoside,quercetin 3-O-neohesperidoside,kaempferol and quer-cetin).Fingerprinting was based on the selection of nine characteristic chromatographic peaks.In quantitative analysis,the recovery of all eight compounds was in the range 98.5-102.2% with good linearity(r^(2)>0.9919)over a relatively wide concentration range.The assay was successfully applied to the analysis of the eight bioactive flavonoids in 14 different samples.The results indicate that the assay is reproducible and precise and can be used for convenient quality assessment of Pollen Typhae. | Le Han Xunhong Liu Nianyun Yang Junsong Li Baochang Cai Shi Cheng | 2012 | Acta Pharmaceutica Sinica B2012，2，6： | 3 |
| 20 | A novel incompressible finite-difference lattice Boltzmann equation for particle-laden flow显示文摘In this paper, we propose a novel incompressible finite-difference lattice Boltzmann Equation (FDLBE). Because source terms that reflect the interaction between phases can be accurately described, the new model is suitable for simulating two-way coupling incompressible multiphase flow.The 2-D particle-laden flow over a backward-facing step is chosen as a test case to validate the present method. Favorable results are obtained and the present scheme is shown to have good prospects in practical applications. | Sheng Chen Zhaohui Liu Baochang Shi Zhu He Chuguang Zheng | 2005 | Acta Mechanica Sinica2005，21，6： | 2 |
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