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| 1 | The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters显示文摘最近的研究在众多的生物过程增加了我们长 noncoding RNA (lncRNAs ) 的理解,但是很少在体的房间 reprogramming 检验了他们的角色。通过表示介绍并且功能的屏蔽,我们鉴别了大 intergenic noncoding RNA p21 (lincRNA-p21 ) 损害 reprogramming。尤其是, lincRNA-p21 被 p53 导致,但是不在 reprogramming 支持 apoptosis 或房间老朽。相反, lincRNA-p21 与 H3K9 methyltransferase SETDB1 和维护 DNA methyltransferase DNMT1 联系,它被 RNA 有约束力的蛋白质 HNRNPK 便于。因而, lincRNA-p21 由在 pluripotency 基因倡导者支撑 H3K9me3 或 CpG methylation 阻止 reprogramming。我们的结果在 reprogramming 提供卓见进 lncRNAs 的角色并且建立在 p53 和 heterochromatin 规定之间的一个新奇连接。 | Xichen Bao Haitao Wu Xihua Zhu Xiangpeng Guo Andrew P Hutchins Zhiwei Luo Hong Song Yongqiang Chen Keyu Lai Menghui Yin Lingxiao Xu Liang Zhou Jiekai Chen Dongye Wang Baoming Qin Jon Frampton Hung-Fat Tse Duanqing Pei Huating Wang Biliang Zhang Miguel A Esteban | 2015 | Cell Research2015，25，1： | 21 |
| 2 | Farmers'Exit from Land Operation in Rural China:Does the Price of Agricultural Mechanization Services Matter?显示文摘This study uses data covering 3,914 farm households,collected from Henan province in China,to investigate the links between the price of agricultural mechanization services and farmers'exit from land operation.The results indicate that the increasing price of agricultural mechanization services leads tofarmers leaving land operation,especially when the high sunk costs and the long-term breakeven period of self-owned machinery are considered.This effect is intensified by the rapid rural-urban migration in China.Further analysis reveals that the surge in service prices reduced land renting-in and encouraged non-grain production.Our analysis suggests that the agricultural mechanization service market in China tends to work against the survival of smallholder farmers.However,the price of agricultural mechanization services is conducive to eliminating less-productive farmers and cultivating new agricultural operators. | Tongwei Qiu S.T.Boris Choy Yifei Li Biliang Luo Jing Li | 2021 | China & World Economy2021，29，2： | 9 |
| 3 | 5-Ethynyl-2′-deoxyuridine as a molecular probe of cell proliferation for high-content siRNA screening assay by “click” chemistry显示文摘Labelling and identification of proliferating cells is important for the study of physiological or pathological processes in high-content screening (HCS) assays. Here we describe ethynyl deoxyuridine (EdU) as a biomarker for the assessment of cell proliferation and clearly demonstrate the feasibility of the EdU-labelling method for use in HCS assays. EdU detection is highly robust, reproducible, technically simple, and well suited for automated segmentation, which provides an excellent al- ternative for setting up multiplexed HCS assays of siRNA, miRNA and small-molecule libraries. | CHEN MiaoJuan QU DeZhong CHI WeiLin WANG Wei REN XiaoShuai CONG ShuJie LIANG PeiZhou FENG ShiPeng ZHANG BiLiang | 2011 | Science China Chemistry2011，54，11： | 6 |
| 4 | Does Land Rent between Acquaintances Deviate from the Reference Point?Evidence from Rural China显示文摘This paper theoretically and empirically investigates whether acquaintance networks influence the deviation of land rent from the reference point advanced by Hart and Moore.The cofficient of variahce and the range of land rent are used to represent the degree of deviation from the reference point.Based on village-level data from the 2015 China Household Finance Survey,the estimated results indicate that land rent between acquaintances is more likely to significantly deviate from the reference point.Although rental transactions are conducted between acquaintances,larger deviations from the reference are also associated with a longer time to close deals.Our analysis using household-level data fiurther supports our findings,indicating that land rental markets embedded in the acquaintance networks of rural China are in a transition period and have characteristics of both relational and market orientation.The policy makers should introduce more outer village lesses or other market ingredients to increase the voluntary marketization of land rentals inside acquaintance networks. | Tongwei Qiu Biliang Luo Qinying He | 2020 | China & World Economy2020，28，3： | 5 |
| 5 | The Impact of the US Interest Rate Hike on Emerging Market Economies and the Belt and Road Initiative显示文摘Since the end of 2015,the US Federal Reserve has raised its benchmark interest rate nine times.This has led to capital outflows and asset depreciation in many emerging market economies.The present paper examines the factors that determine the financial volatility of emerging markets in the face of external shocks.By calculating the capital flows of 30 emerging markets from 1990 to 2018 and conducting panel regression,this paper finds that countries with good infrastructure facilities,a sound banking system and high economic growth have significantly lower cross-border financial risks.An implication from the empirical analysis is that emerging countries would benefit greatly by actively taking part in the Belt and Road Initiative.The framework of the Belt and Road Initiative allows emerging countries better access to China s massive consumer market to promote trade and long-term growth.Their quality of infrastructure can be improved through cooperation with China in infrastructure investment.They can also jointly establish a cooperative financial framework to enhance regional financial stability.These strategies will reduce systematic financial risks and counteract the negative impacts of US interest rate hikes. | Shuyu Wu Biliang Hu Qingzhong Pan | 2019 | China & World Economy2019，27，3： | 3 |
| 6 | RNA therapeutics:updates and future potential显示文摘Recent advancements in the production,modification,and cellular delivery of RNA molecules facilitated the expansion of RNAbased therapeutics.The increasing understanding of RNA biology initiated a corresponding growth in RNA therapeutics.In this review,the general concepts of five classes of RNA-based therapeutics,including RNA interference-based therapies,antisense oligonucleotides,small activating RNA therapies,circular RNA therapies,and messenger RNA-based therapeutics,will be discussed.Moreover,we also provide an overview of RNA-based therapeutics that have already received regulatory approval or are currently being evaluated in clinical trials,along with challenges faced by these technologies.RNA-based drugs demonstrated positive clinical trial results and have the ability to address previously“undruggable”targets,which delivers great promise as a disruptive therapeutic technology to fulfill its full clinical potentiality. | Caroline Zhang Biliang Zhang | 2023 | Science China(Life Sciences)2023，66，1： | 2 |
| 7 | People's Mobility and Guanxi Networks:A Case Study显示文摘人从的运动的增加对城市的区域农村后来, mid-1980s 代表曾经在中国经验丰富的最大的劳动迁居。因为移植是选择的进程,决定选择的主要动力学被学习,是必要的。帮助他们从农村区域认识到他们的活动性到城市的区域的候鸟的批评特征是什么?当教育成就,性,年龄,婚姻状况和个人技巧是在选择进程的重要变量时,现在的纸检验社会网络(guanxi 连接) 怎么在中国在移植选择的进程起一个重要作用。来自在农村中国的北村庄之一的案例研究被用来探索社会网络怎么塑造了并且给意思到移植。现在的纸在人的社会活动性怎么与一致与上详细描述并且由人的物理活动性增强了。 | Biliang Hu | 2008 | China & World Economy2008，16，5： | 1 |
| 8 | Cholesterol recognition and binding by cyclodextrin dimers显示文摘 | Ronald B Biliang Z | 1996 | JAm Chem Soc1996，118，： | 1 |
| 9 | Developing Social Citizenship? A Case Study of Education and Health Services in Yantian Village of Guangdong Province显示文摘社会政策是统治的一个不可缺少的元素,中国的当前的领导移动了政策到更多包括系统基于公民资格的一个观点。社会福利预备的延期在 Yantian 的华南村庄里通过教育和护理的案例研究被检验。Yantian 躺在珍珠河三角洲的核心,它在生产和生产的全球重组成为了一个关键连接。因而村庄在家到补充 3000 个登记居民的大约 80 000 个候鸟工人。教育和保健预备的研究以公平揭示那,登记村民在寻求福利资源享受重要优点。尽管住在一样的村庄,二个组住在不同世界。然而,预备选择,成为了更多包括。现在的研究建议社会公民资格将先于政治公民资格。 | Biliang Hu Tony Saich | 2012 | China & World Economy2012，20，3： | 1 |
| 10 | A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts显示文摘 | Ronghui Li Jialiang Liang Su Ni Ting Zhou Xiaobing Qing Huapeng Li Wenzhi He Jiekai Chen Feng Li Qiang Zhuang Baoming Qin Jianyong Xu Wen Li Jiayin Yang Yi Gan Dajiang Qin Shipeng Feng Hong Song Dongshan Yang Biliang Zhang Lingwen Zeng Liangxue Lai Miguel | 2010 | Cell Stem Cell2010，，1： | 1 |
| 11 | A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts显示文摘 | Ronghui Li Jialiang Liang Su Ni Ting Zhou Xiaobing Qing Huapeng Li Wenzhi He Jiekai Chen Feng Li Qiang Zhuang Baoming Qin Jianyong Xu Wen Li Jiayin Yang Yi Gan Dajiang Qin Shipeng Feng Hong Song Dongshan Yang Biliang Zhang Lingwen Zeng Liangxue Lai Miguel | 2010 | Cell Stem Cell2010，，1： | 1 |
| 12 | The characteristics and failure mechanism of the largest landslide triggered by the Wenchuan earthquake, May 12, 2008, China显示文摘 | Runqiu Huang Xiangjun Pei Xuanmei Fan Weifeng Zhang Shigui Li Biliang Li | 2012 | Landslides2012，，1： | 1 |
| 13 | KPNB1 , XPO7 and IPO8 Mediate the Translocation of NF‐κB /p65 into the Nucleus显示文摘 | Peizhou Liang Haiyan Zhang Guoxin Wang Suping Li Shujie Cong Yingyun Luo Biliang Zhang | 2013 | Traffic2013，，11： | 1 |
| 14 | RNAi screen to identify protein phosphatases that regulate the NF-kappaB signaling显示文摘NF-kappaB plays a critical role in cell survival,apoptosis,and inflammatory responses.Serine/threoninespecific phosphatases(PPs)represent the second major class of enzymes that catalyze the dephosphorylation of proteins.The roles of PPs regulating NF-kappaB activities are poorly understood.Here we describe an RNAi-based screen to identify the PPs that involve in regulating NFkappaB signaling.Thirty-four candidate PPs siRNAs were synthesized and primarily screened by NF-kappaB reporter gene assay in HeLa cells.PHLPP,one of the protein phosphatase type 2C family members(PP2C),was identified as a positive regulator of NF-kappaB signaling.Knock-down of PHLPP dramatically attenuated TNFα-stimulated NF-kappaB transcriptional activation.Knockdown of PHLPP led to enhancement of NF-kappaB/p65 nuclear import and retention,but decreased TNFα-induced phosphorylation at Ser276 on p65.This critical phosphorylation was also drastically reduced by knock-down of PKCalpha and Akt1,two important serine/threonine kinases dephosphorylated by PHLPP.The results together suggest that PHLPP-Akt-PKC may represent an important signaling loop that activates NF-kappaB/p65 signaling through critical serine phosphorylation. | Guoxin WANG Suping LI Feifei WANG Shufang HUANG Xian LI Wei XIONG Biliang ZHANG | 2010 | Frontiers in Biology2010，5，3： | 0 |
| 15 | Commitment to Globalization显示文摘Today, globalization is poisedat a crossroads. With thegrowth of the volume of worldtrade, foreign investment iswidespread and the numberof transnational corporationscontinues growing, yet theworld economy is facing severestability challenges that havecreated widespread worry anddoubt. However, globalization remains an irreversible trend,and the tide of economic, tradeand technological cooperationhas not reversed. | Hu Biliang | 2019 | China Report ASEAN2019，4，12： | 0 |
| 16 | China’s Key to Success显示文摘Forty years of reform and opening-up have brought about sweeping changes in China.Bolstering the nation’s rise is political stability underpinned by the centralized,unified leadership of the Communist Party of China(CPC)and economic vigor sustained by advances in infrastructure,manufacturing and foreign investment.While pursuing market-oriented reform,China puts its back into international economic cooperation resulting in mutual benefits. | HU BILIANG | 2018 | China Today2018，67，1： | 0 |
| 17 | FRUITFUL EXPLORATION显示文摘Forty years ago,China entered a new development stage when the country launched the reform and opening-up drive.Since then,it has made tremendous achievements and gained valuable experience, a review of which will illuminate the future. | Hu Biliang | 2018 | Beijing Review2018，61，52： | 0 |
| 18 | The Key to Success显示文摘At the end of 1976,China was,by and large,an agricultural country with a hefty 82.6 percent of its population living in the countryside,the majority in absolute poverty.After a decade of the'cultural revolution'(1966-76)that concluded in October that year,the Chinese economy had come to the verge of collapse,and its political system was in disarray.It was in these circumstances that the Chinese people | Hu Biliang | 2018 | Beijing Review2018，61，1： | 0 |
| 19 | Recovery Through Collaboration显示文摘Closer China-Africa cooperation can minimize the impact of pandemic on AfricaAlthough the number of confirmed COVID-19 patients in Africa is not large and accounts for only a small proportion of confirmed cases in the world so far,the pandemic has dealt a heavy blow to the African economy and the negative impact is likely to continue for a period of time and even exacerbate.Therefore,e ective measures need to be taken to alleviate the impact of the pan-demic on the African economy as soon as possible.Strengthening China-Africa cooperation should be one of the measures. | Hu Biliang | 2020 | ChinAfrica2020，12，6： | 0 |
| 20 | Advancing Development Sustainable Belt and Road cooperation benefits all participants显示文摘Since the Belt and Road Initiative was proposed in 2013,China’s total non-financial direct investment in countries along the Belt and Roadroutes has reached$104.72 billion,according to the Ministry of Commerce. | Hu Biliang | 2021 | ChinAfrica2021，13，4： | 0 |
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