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| 1 | Combined Applications of Nitrogen and Phosphorus Fertilizers with Manure Increase Maize Yield and Nutrient Uptake via Stimulating Root Growth in a Long-Term Experiment显示文摘Imbalanced application of nitrogen(N) and phosphorus(P) fertilizers can result in reduced crop yield,low nutrient use efficiency,and high loss of nutrients and soil nitrate nitrogen(NO_3^--N) accumulation decreases when N is applied with P and/or manure;however,the effect of applications of N with P and/or manure on root growth and distribution in the soil profile is not fully understood.The aim of this study was to investigate the combined effects of different N and P fertilizer application rates with or without manure on maize(Zea mays L.) yield,N uptake,root growth,apparent N surplus,Olsen-P concentration,and mineral N(N_(min)) accumulation in a fluvo-aquic calcareous soil from a long-term(28-year) experiment.The experiment comprised twelve combinations of chemical N and P fertilizers,either with or without chicken manure,as treatments in four replicates.The yield of maize grain was 82%higher,the N uptake 100%higher,and the N_(min) accumulation 39%lower in the treatments with combined N and P in comparison to N fertilizer only.The maize root length density in the 30-60 cm layer was three times greater in the treatments with N and P fertilizers than with N fertilizer only.Manure addition increased maize yield by 50%and N uptake by 43%,and reduced N_(min)(mostly NO_3^--N) accumulation in the soil by 46%.The long-term application of manure and P fertilizer resulted in significant increases in soil Olsen-P concentration when no N fertilizer was applied.Manure application reduced the apparent N surplus for all treatments.These results suggest that combined N and P fertilizer applications could enhance maize grain yield and nutrient uptake via stimulating root growth,leading to reduced accumulation of potentially leachable NO_3^--N in soil,and manure application was a practical way to improve degraded soils in China and the rest of the world. | WEN Zhihui SHEN Jianbo Martin BLACKWELL LI Haigang ZHAO Bingqiang YUAN Huimin | 2016 | Pedosphere2016，26，1： | 29 |
| 2 | Neighbor sum distinguishing total colorings of K4-minor free graphs显示文摘一个总数[k ] 图 G 的着色是印射:V (G) E (G){ 1, 2,, k } 以便在 V (G) E (G) 的任何二个邻近的元素收到不同颜色。让 f (v) 表示顶点 v 的颜色和 v 的所有事件边的颜色的和。一个总数[k ] G 的邻居和区分着色是一个总数[k ] G 的着色以便为每边 uv E (G) , f (u) f (v) 。由 nsd,我们在 G 的如此的着色表示最小的价值 k。Pilniak 和 Woniak 与最大的度(G) 为任何简单的图推测了 nsd (G)(G)+3。这推测为完全的图,周期,由两部组成的图,和 subcubic 图被证明了。在这份报纸,我们证明它也为 K 4 未成年者保持免费的图。而且,我们看那 G 是否是一个 K 4 未成年者有(G) 的免费的图 4,然后 gc nsd (G)(G)+ 2。2 突然地是的界限(G)+ 。 | Hualong LI Bingqiang LIU Guanghui WANG | 2013 | Frontiers of Mathematics in China2013，8，6： | 23 |
| 3 | Chromosome-scale genome assembly provides insights into the evolution and flavor synthesis of passion fruit (Passiflora edulis Sims)显示文摘Passion fruit(Passiflora edulis Sims)is an economically valuable fruit that is cultivated in tropical and subtropical regions of the world.Here,we report an~1341.7Mb chromosome-scale genome assembly of passion fruit,with 98.91%(~1327.18Mb)of the assembly assigned to nine pseudochromosomes.The genome includes 23,171 protein-coding genes,and most of the assembled sequences are repetitive sequences,with long-terminal repeats(LTRs)being the most abundant.Phylogenetic analysis revealed that passion fruit diverged after Brassicaceae and before Euphorbiaceae.Ks analysis showed that two whole-genome duplication events occurred in passion fruit at 65 MYA and 12 MYA,which may have contributed to its large genome size.An integrated analysis of genomic,transcriptomic,and metabolomic data showed that‘alpha-linolenic acid metabolism’,‘metabolic pathways’,and‘secondary metabolic pathways’were the main pathways involved in the synthesis of important volatile organic compounds(VOCs)in passion fruit,and this analysis identified some candidate genes,including GDP-fucose Transporter 1-like,Tetratricopeptide repeat protein 33,protein NETWORKED 4B isoform X1,and Golgin Subfamily A member 6-like protein 22.In addition,we identified 13 important gene families in fatty acid pathways and eight important gene families in terpene pathways.Gene family analysis showed that the ACX,ADH,ALDH,and HPL gene families,especially ACX13/14/15/20,ADH13/26/33,ALDH1/4/21,and HPL4/6,were the key genes for ester synthesis,while the TPS gene family,especially PeTPS2/3/4/24,was the key gene family for terpene synthesis.This work provides insights into genome evolution and flavor trait biology and offers valuable resources for the improved cultivation of passion fruit. | Zhiqiang Xia Dongmei Huang Shengkui Zhang Wenquan Wang Funing Ma Bin Wu Yi Xu Bingqiang Xu Di Chen Meiling Zou Huanyu Xu Xincheng Zhou Rulin Zhan Shun Song | 2021 | Horticulture Research2021，8，1： | 15 |
| 4 | Bevacizumab biosimilar LY01008 compared with bevacizumab(Avastin)as first-line treatment for Chinese patients with unresectable,metastatic,or recurrent non-squamous non-small-cell lung cancer:A multicenter,randomized,double-blinded,phase Ⅲ trial显示文摘Background:Previous studies have demonstrated the preclinical pharmacological and toxicological consistency,and clinical pharmacokinetic equivalence of bevacizumab biosimilar LY01008 with reference bevacizumab(Avastin).This randomized controlled trial aimed to compare the efficacy and safety of LY01008 with Avastin in first-line treatment of Chinese patients with advanced or recurrent non-squamous non-small cell lung cancer(NSCLC).Methods:StageⅢB-ⅣNSCLC patients with evaluable lesions,good physical status,and adequate organ functions from 67 centers across China were randomized in a ratio of 1:1 to receive LY01008 or Avastin 15 mg/kg intravenously in combination with paclitaxel/carboplatin(combined treatment)for 4-6 cycles,followed by maintenance monotherapy with LY01008 until disease progression,intolerable toxicity,or death.The primary endpoint was objective response rate(ORR)in accordance with Response Evaluation Criteria in Solid Tumors(RECIST)version 1.1 confirmed by independent radiological review committees(IRRC).Secondary endpoints included disease control rate(DCR),duration of response(DoR),progression-free survival(PFS),overall survival(OS),and safety.This study was registered in Clinical Trials.gov(NCT03533127).Results:Between December 15^(th),2017,and May 15^(th),2019,a total of 649 patients were randomized to the LY01008(n=324)or Avastin(n=325)group.As of September 25th,2019 for primary endpoint analysis,589 patients received ORR evaluation,with a median number of combined treatment cycles of 5(range 1-6)andmedian duration of treatment of 3.0(range 0.0-5.1)months.ORRof responseevaluable patients in the LY01008 and Avastin groups were 48.5% and 53.0%,respectively.The stratified ORR ratio was 0.91(90%CI 0.80-1.04,within the prespecified equivalence margin of 0.75-1.33).Up to May 15^(th),2020,with a median follow-up of 13.6(range 0.8-28.4)months,no notable differences in DCR,median DoR,median PFS,median OS,and 1-year OS rate were observed between the LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,or recurrent non-squamous NSCLC patients in the first-line setting. | Yuankai Shi Kaijian Lei Yuming Jia Bingqiang Ni Zhiyong He Minghong Bi Xicheng Wang Jianhua Shi Ming Zhou Qian Sun Guolei Wang Dongji Chen Yongqian Shu Lianke Liu Zhongliang Guo Yong Liu Junquan Yang Ke Wang Ke Xiao LinWu Tienan Yi Debin Sun Mafei Kang Tianjiang Ma Yimin Mao Jinsheng Shi Tiegang Tang Yan Wang Puyuan Xing Dongqing Lv Wangjun Liao Zhiguo Luo Bin Wang Xiaohong Wu Xiaoli Zhu Shuhua Han Qisen Guo Rongyu Liu Zhiwei Lu Jianyong Zhang Jian Fang Changlu Hu Yinghua Ji Guolong Liu Hong Lu Dedong Wu Junhong Zhang Shuyang Zhu Zheng Liu Wensheng Qiu Feng Ye Yan Yu Yanqiu Zhao Qinhong Zheng Jun Chen Zhanyu Pan Yiping Zhang Wenjuan Lian Bo Jiang Bo Qiu Guojun Zhang Hua Zhang Yanju Chen Yuan Chen Hongbing Duan Manxiang Li Shengming Liu Lijun Ma Hongming Pan Xia Yuan Xueli Yuan Yulong Zheng Emei Gao Li Zhao Shumin Wang Can Wu | 2021 | Cancer Communications2021，41，9： | 5 |
| 5 | A critical survey of technologies of large offshore wind farm integration: summary, advances, and perspectives显示文摘Offshore wind farms(OWFs)have received widespread attention for their abundant unexploited wind energy poten-tial and convenient locations conditions.They are rapidly developing towards having large capacity and being located further away from shore.It is thus necessary to explore effective power transmission technologies to connect large OWFs to onshore grids.At present,three types of power transmission technologies have been proposed for large OWF integration.They are:high voltage alternating current(HVAC)transmission,high voltage direct current(HVDC)transmission,and low-frequency alternating current(LFAC)or fractional frequency alternating current transmission.This work undertakes a comprehensive review of grid connection technologies for large OWF integration.Compared with previous reviews,a more exhaustive summary is provided to elaborate HVAC,LFAC,and five HVDC topologies,consisting of line-commutated converter HVDC,voltage source converter HVDC,hybrid-HVDC,diode rectifier-based HVDC,and all DC transmission systems.The fault ride-through technologies of the grid connection schemes are also presented in detail to provide research references and guidelines for researchers.In addition,a comprehensive evalu-ation of the seven grid connection technologies for large OWFs is proposed based on eight specific indicators.Finally,eight conclusions and six perspectives are outlined for future research in integrating large OWFs. | Bo Yang Bingqiang Liu Hongyu Zhou Jingbo Wang Wei Yao Shaocong Wu Hongchun Shu Yaxing Ren | 2022 | Protection and Control of Modern Power Systems2022，7，1： | 4 |
| 6 | Nitrogen release characteristics of polyethylene-coated controlled-release fertilizers and their dependence on membrane pore structure显示文摘 | Xiangdong Yang Rongfeng Jiang Yangzheng Lin Yanting Li Juan Li Bingqiang Zhao | 2018 | Particuology2018，16，1： | 4 |
| 7 | A predicted NEDD8 conjugating enzyme gene identified as a Capsicum candidate Rf gene using bulk segregant RNA sequencing显示文摘Cytoplasmic male sterility(CMS)is an important tool for producing F1 hybrids,which can exhibit heterosis.The companion system,restorer-of-fertility(Rf),is poorly understood at the molecular level and would be valuable in producing restorer lines for hybrid seed production.The identity of the Rf gene in Capsicum(pepper)is currently unclear.In this study,using bulked segregant RNA sequencing(BSR-seq),a strong candidate Rf gene,Capana06g002866,which is annotated as a NEDD8 conjugating enzyme E2,was identified.Capana06g002866 has an ORF of 555 bp in length encoding 184 amino acids;it can be cloned from F1 plants from the hybridization of the CMS line 8A and restorer line R1 but is not found in CMS line 8A.With qRT-PCR validation,Capana06g002866 was found to be upregulated in restorer accessions compared to sterile accessions.The relative expression in flower buds increased with the developmental stage in F1 plants,while the expression was very low in all flower bud stages of the CMS lines.These results provide new insights into the Rf gene in pepper and will be useful for other crops utilizing the CMS system. | Bingqiang Wei Paul W.Bosland Zhenghai Zhang Yongfu Wang Gaoyuan Zhang Lanlan Wang Jihua Yu | 2020 | Horticulture Research2020，7，1： | 3 |
| 8 | SOCS3 Attenuates GM-CSF/IFN-γ-Mediated Inflammation During Spontaneous Spinal Cord Regeneration显示文摘SOCS3,a feedback inhibitor of the JAK/STAT signal pathway,negatively regulates axonal regrowth and inflammation in the central nervous system(CNS).Here,we demonstrated a distinct role of SOCS3 in the injured spinal cord of the gecko following tail amputation.Severing the gecko spinal cord did not evoke an inflammatory cascade except for an injury-stimulated elevation of the granulocyte/macrophage colony-stimulating factor(GM-CSF) and interferon gamma(IFN-γ) cytokines.Simultaneously,the expression of SOCS3 was upregulated in microglia,and unexpectedly not in neurons.Enforced expression of SOCS3 was sufficient to suppress the GMCSF/IFN-γ-driven inflammatory responses through its KIR domain by attenuating the activities of JAK1 and JAK2.SOCS3 was also linked to GM-CSF/IFN-y-induced crosstolerance.Transfection of adenovirus overexpressing SOCS3 in the injured cord resulted in a significant decrease of inflammatory cytokines.These results reveal a distinct role of SOCS3 in the regenerating spinal cord,and provide new hints for CNS repair in mammals. | Xuejie Zhang Bingqiang He Hui Li Yingjie Wang Yue Zhou Wenjuan Wang Tiancheng Song Nan Du Xingxing Gu Yi Luo Yongjun Wang | 2020 | Neuroscience Bulletin2020，36，7： | 3 |
| 9 | Distribution of Helium Resources in Weihe Basin,Central China:Insight from 3D Magnetic Inversion显示文摘There is promising indication of helium-rich natural gas in Weihe Basin.However,the lack of a detailed investigation on the origin and the spatial distribution of helium source rocks(mainly Yanshanian granites)limits the helium potentiality evaluation in Weihe Basin(WB).We performed three-dimensional(3 D)inversions of magnetic data in Weihe Basin and its adjacent areas to figure out the crustal thermal structure and the temporal-spatial distribution of deep granite in the basin.Based on this,we have proposed a geological model of helium accumulation and predicted the potential area of helium distribution.The results of 3 D magnetic inversion indicate that the granites in the deep Weihe Basin are mostly located at the central and southern parts of the basin,which are connected spatially with the granites in the North Qinling Orogenic Belt.These granites were all derived from largescale intra-continental orogeny in the Qinling area during the mid-Mesozoic,providing a good material basis for crust-derived helium in the basin.The local uplift of the Curie surface makes the thermal fluid more actively,which contributes to helium accumulation.The faults developed in the WB are the migration pathway of crust-derived helium and the upward migration of the mantle-derived helium.The wells with high percentage helium are mostly located near the Weihe fault and the areas on the south of it.The Wugong-Xi’an-Lantian area in the central and the Lintong-Weinan-Tongguan area in the eastern Weihe Basin are the most promising helium distribution areas.Furthermore,the region from the north of Taibai Mountain to Baoji City in the western Weihe Basin may also be another potential area of Helium resource. | Xuliang Feng Bingqiang Yuan Yuhong Li Chunguan Zhang Lijun Song | 2022 | Journal of Earth Science2022，33，4： | 3 |
| 10 | A waveform modification method for testing dynamic properties of rock under high temperature显示文摘In this study,a waveform modification method was proposed using a self-designed heating device combined with the split Hopkinson pressure bar(SHPB)technique for determination of dynamic behaviors of rock at high temperature.Firstly,the temperature gradient distribution on the incident bar was measured according to the variation of elastic modulus of the bar with temperature,and the relationship between the longitudinal wave velocity and temperature of the bar was obtained based on onedimensional stress wave theory.The incident bar with a temperature gradient was divided into a series of microelements,and then the transmission coefficient of the whole incident bar was obtained.Finally,the stress wave was modified by the transmission coefficient from 25℃ to 600℃.This method was used to study the dynamic properties of rock at high temperature,which not only preserves a classical SHPB device,but also effectively ensures the accuracy of the experimental results.A dynamic Brazilian disc experiment was carried out to explore the influences of loading rate and temperature on dynamic tensile strength of sandstone at high temperature using the proposed waveform modification method. | Tubing Yin Chao Wang You Wu Bingqiang Wu | 2021 | Journal of Rock Mechanics and Geotechnical Engineering2021，13，4： | 2 |
| 11 | Microwave-assisted hydrothermal synthesis and gas sensitivity of nanostructured SnO_2显示文摘Precursors for nanostructured SnO_2 were synthesized via a microwave-assisted hydrothermal method under different conditions,using SnCl_2·2H_2O,urea and citric acid as reactants.After calcination of the precursors at 700℃for 2 h,nanostructured SnO_2 with different morphologies were obtained,and were then characterized using X-ray powder diffraction(XRD),and field-emission scanning electron microscopy(FESEM).The results show that synthesis temperature and time play an important role in the formation of the 3D hierarchical morphology of the nanostructured SnO_2.Gas sensing experiments demonstrate that the synthesized SnO_2 materials,especially those with a 3D network structure,exhibit superb sensitivity to alcohol vapors at 240℃. | Liying Man Jun Zhang Jieqiang Wang Hongyan Xu Bingqiang Cao | 2013 | Particuology2013，11，2： | 2 |
| 12 | Prospect of Functional Salivary Gland Enhancement with Biomedical Strategies for Head and Neck Cancers显示文摘Xerostomia is the main complication inflicting head and neck cancer patients treated with radiotherapy.Conventional treatment is not very effective in alleviating this morbidity.Biomedical strategies such as gene transfer and tissue engineering have made substantial progress that will potentially lead to successful new treatment options for this condition.This report reviews the process of radiation damage to the salivary glands and the advances in functional salivary gland enhancement with these two brand-new technologies. | Suyu Zhu Bingqiang Hu Xiao Zhou | 2008 | Chinese Journal of Clinical Oncology2008，5，5： | 2 |
| 13 | GTB-PPI:Predict Protein-protein Interactions Based on L1-regularized Logistic Regression and Gradient Tree Boosting显示文摘Protein-protein interactions(PPIs)are of great importance to understand genetic mechanisms,delineate disease pathogenesis,and guide drug design.With the increase of PPI data and development of machine learning technologies,prediction and identification of PPIs have become a research hotspot in proteomics.In this study,we propose a new prediction pipeline for PPIs based on gradient tree boosting(GTB).First,the initial feature vector is extracted by fusing pseudo amino acid composition(Pse AAC),pseudo position-specific scoring matrix(Pse PSSM),reduced sequence and index-vectors(RSIV),and autocorrelation descriptor(AD).Second,to remove redundancy and noise,we employ L1-regularized logistic regression(L1-RLR)to select an optimal feature subset.Finally,GTB-PPI model is constructed.Five-fold cross-validation showed that GTB-PPI achieved the accuracies of 95.15% and 90.47% on Saccharomyces cerevisiae and Helicobacter pylori datasets,respectively.In addition,GTB-PPI could be applied to predict the independent test datasets for Caenorhabditis elegans,Escherichia coli,Homo sapiens,and Mus musculus,the one-core PPI network for CD9,and the crossover PPI network for the Wnt-related signaling pathways.The results show that GTB-PPI can significantly improve accuracy of PPI prediction.The code and datasets of GTB-PPI can be downloaded from https://github.com/QUST-AIBBDRC/GTB-PPI/. | Bin Yu Cheng Chen Hongyan Zhou Bingqiang Liu Qin Ma | 2020 | Genomics, Proteomics & Bioinformatics2020，18，5： | 2 |
| 14 | Adaptive adjustment of iterative learning control gain matrix in harsh noise environment显示文摘For the robustness problem of open-loop P-type iterative learning control under the influence of measurement noise which is inevitable in actual systems,an adaptive adjustment algorithm of iterative learning nonlinear gain matrix based on error amplitude is proposed and two nonlinear gain functions are given. Then with the help of Bellman-Gronwall lemma,the robustness proof is derived.At last,an example is simulated and analyzed. The results show that when there exists measurement noise,the proposed learning law adjusts the learning gain matrix on line based on error amplitude,thus can make a compromise between learning convergence rate and convergence accuracy to some extent:the fast convergence rate is achieved with high gain in initial learning stage,the strong robustness and high convergence accuracy are achieved at the same time with small gain in the end learning stage,thus better learning results are obtained. | Bingqiang Li Hui Lin Hualing Xing | 2013 | Journal of Systems Engineering and Electronics2013，24，1： | 2 |
| 15 | An improved YOLOv3-tiny algorithm for vehicle detection in natural scenes显示文摘YOLO(You Only Look Once),as a target detection algorithm with good speed and precision,is widely used in the industry.In the process of driving,the vehicle image captured by the driving camera is detected and it extracts the license plate and the front part of the vehicle.Compared with the network structure of YOLOv3-tiny algorithm,the acquisition method of anchor box is improved by combining the Birch algorithm.In order to improve the real-time performance,the original two-scale detection is added to the multi-scale prediction of three-scale detection to ensure its accuracy.Finally,the experimental results show that the improved YOLOv3-tiny network structure proposed in this study can improve the performance of mean-average-precision,intersection over union and speed by 5.99%,17.52%and 48.4%,respectively,and the algorithm has certain robustness. | Bingqiang Huang Haiping Lin Zejun Hu Xinjian Xiang Jiana Yao | 2021 | IET Cyber-Systems and Robotics2021，3，3： | 2 |
| 16 | Effects of no-tillagemanagement on soil biochemical characteristics in Northern China显示文摘 | Liu Enke Zhao Bingqiang Mei Xurong | 2010 | Agric Sci Camb2010，148，2： | 1 |
| 17 | Preparation of β-SiC/AI2O3 composite from kaolinite gangue by carbthermal reduction显示文摘 | HAN Bingqiang LI Nan | 2005 | Ceram In2005，31，2： | 1 |
| 18 | Hierarchical Co3O4 Nanowires as Binder Free Electrodes for Reversible Lithium Storage显示文摘 | Zichao Zhang Li Li Quan Ren Qi Xu Bingqiang Cao | 2016 | Chinese Journal of Chemistry2016，34，6： | 1 |
| 19 | A new strategy for the fabrication of the phosphor polyoxomolybdate modified electrode from ionic liquid solutions and its electrocatalytic activities显示文摘 | Huang Bingqiang Wang Li Shi Kang | 2008 | Journal of Electroanalytical Chemistry2008，165，1： | 1 |
| 20 | An efficient all-zero-block detection method for general orthogonal transformations显示文摘 | Zhu Bingqiang Tong Xin An Da | | 0，，04： | 1 |
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