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| 1 | Covert hepatic encephalopathy: Agreement and predictive validity of different indices显示文摘AIM:To investigate the agreement and prognosticvalue of different measures of covert hepatic encephalopathy(CHE).METHODS:One-hundred-and-thirty-two cirrhotic outpatients underwent electroencephalography(EEG),paper-and-pencil psychometry(PHES)and critical flicker frequency,scored on the original/modified(CFFo/CFFm)thresholds.Eighty-four patients underwent Dopplerultrasound to diagnose/exclude portal-systemic shunt.Seventy-nine were followed-up for 11±7 mo in relation to the occurrence of hepatic encephalopathy(HE)-related hospitalisations.RESULTS:On the day of study,36%had gradeⅠHE,42%abnormal EEG,33%abnormal PHES and 31/21%abnormal CFFo/CFFm.Significant associations were observed between combinations of test abnormalities;however,agreement was poor(Cohen’sκ<0.4).The prevalence of EEG,PHES and CFFo/CFFm abnormalities was significantly higher in patients with gradeⅠovert HE.The prevalence of EEG and CFFm abnormalities was higher in patients with shunt.The prevalence of EEG abnormalities was significantly higher in patients with a history of HE.During follow-up,10 patients died,10were transplanted and 29 had HE-related hospitalisations.GradeⅠHE(P=0.004),abnormal EEG(P=0.008)and abnormal PHES(P=0.04)at baseline all predicted the subsequent occurrence of HE;CFF did not.CONCLUSION:CHE diagnosis probably requires a combination of clinical,neurophysiological and neuropsychological indices. | Sara Montagnese Esmeralda Balistreri Sami Schiff Michele De Rui Paolo Angeli Giacomo Zanus Umberto Cillo Giancarlo Bombonato Massimo Bolognesi David Sacerdoti Angelo Gatta Carlo Merkel Piero Amodio | 2014 | World Journal of Gastroenterology2014，20，42： | 6 |
| 2 | Initial experience with partialleft ventriculectomy as a treatment for end-stage heart failure显示文摘 | Bombonato R Bestetti RB Sgarbieri R | 1996 | Arq BrasCardiol1996，66，： | 1 |
| 3 | Clinical coures of patients treatedwith partial left ventriculectomy显示文摘 | Bestetti RB Bombonato R Kato M | 1997 | Arq Bras cardiol1997，68，： | 1 |
| 4 | Arterioportal fistulas in patients with liver cirrhosis:usefulness of color Doppler US for screening显示文摘 | Bolognesi M Sacerdoti D Bombonato G | 2000 | Radiology2000，216，3： | 1 |
| 5 | Histometric analysis of rat alveolar wound healing 显示文摘 | Bombonato KF Brentegani LG | 1997 | Braz Dent J1997，8，1： | 1 |
| 6 | Arterioportal fistulas in patients with liver cirrhosis: usefulness of color Doppler US for screening显示文摘 | Bolognesi M Sacerdoti D Bombonato C | 2000 | Radiology2000，216，3： | 1 |
| 7 | Change in portal flow after liver transplantation:effect on hepatic arterial resistance indices and role os spleen size显示文摘 | Massimo bolognesi David sacerditi Giancarlo Bombonato at al | 2002 | Hepatology2002，，： | 1 |
| 8 | Arterioportal fistulas in patient with liver cirrhosis:usefulness of color Doppler US for screening显示文摘 | Bolognesi M Sacerdoti D Bombonato G | 2000 | Radiology2000，216，3： | 1 |
| 9 | Central Nervous System Alterations in Liver Cirrhosis: The Role of Portal-Systemic Shunt and Portal Hypoperfusion显示文摘 | Franco Del Piccolo David Sacerdoti Piero Amodio Giancarlo Bombonato Massimo Bolognesi Daniela Mapelli Angelo Gatta | 2003 | Metabolic Brain Disease2003，，1： | 1 |
| 10 | Change in portal flow after liver transplantation:effect on hepatic arterial resistance indices and role of spleen size显示文摘 | Bolognesi M Sacerdoti D Bombonato G | 2002 | Hepatology2002，35，3： | 1 |
| 11 | Change in portal flow after liver transplantation: effect on hepatic arterial resistance indices and role of spleen size显示文摘 | Bolognesi M Sacerdoti D Bombonato G | 2002 | Hepatology2002，35，3： | 1 |
| 12 | Cell therapy stimulates bone neoformation in calvaria defects in rats subjected to local irradiation显示文摘Background:The purpose of the study was to analyze the effect of cell therapy on the repair process in calvaria defects in rats subjected to irradiation.Methods:Bone marrow mesenchymal cells were characterized for osteoblastic phenotype.Calvariae of male Wistar rats were irradiated(20 Gy)and,after 4 weeks,osteoblastic cells were placed in surgically created defects in irradiated(IRC)and control animals(CC),paired with untreated irradiated(IR)and control(C)animals.After 30 days,histological and microtomographic evaluation was performed to establish significant(P<0.05)differences among the groups.Results:Higher alkaline phosphatase detection and activity,along with an increase in mineralized nodules,in the IRC,C and CC groups compared to the IR group,confirmed an osteoblastic phenotype.Histology showed impaired bone neoformation following irradiation,affecting bone marrow composition.Cell therapy in the IRC group improved bone neoformation compared to the IR group.Microtomography revealed increased bone volume,bone surface and trabecular number in IRC group compared to the IR group.Conclusion:Cell therapy may improve bone neoformation in defects created after irradiation. | Ana Luisa Riul Sorio Paula Katherine Vargas‐Sanchez Roger Rodrigo Fernandes Dimitrius Leonardo Pitol Luiz Gustavo de Sousa Adriano Luiz Balthazar Bianchini Geraldo Batista de Melo Selma Siessere Karina Fittipaldi Bombonato‐Prado | 2019 | Animal Models and Experimental Medicine2019，2，3： | 1 |
| 13 | Splenic impedance indices:a useful method to monitor patients after liver transplantation显示文摘 | Bolognesi M Sacerdoti D Bombonato G | | 0，，03： | 1 |
| 14 | Splenic impedance indices:Auseful method to monitor patients ofter liver transplantation显示文摘 | Boiognesi M Sacerdoti Bombonato D | 1998 | Hepatology1998，27，3： | 1 |
| 15 | Change in portal flow after liver transplantation: effect on hepatic arte- rial resistance indices and role of spleen size显示文摘 | Bolognesi M Sacerdoti D Bombonato G | 2002 | Hepatolo- gy2002，35，： | 1 |
| 16 | Change in portal flow after liver transplantation: effect on hepatic arterial resistance indices and role of spleen size 显示文摘 | Bolognesi M Sacerdoti D Bombonato G | 2002 | Hepatology2002，35，3： | 1 |
| 17 | Change in Portal flow after Liver Transplantation:effect on hepatical aterial resistance indice and role of spleen size显示文摘 | Bolognesi M Sacerdoti D Bombonato G | 2002 | Hepatology2002，35，3： | 1 |
| 18 | Arterioportal fistulas in patients with liver cirrhosis: usefulness of color Doppler US for screening 显示文摘 | Bolognesi M Sacerdoti D Bombonato G | 2000 | Radiology2000，216，3： | 1 |
| 19 | Change in portal flow after liver transplantation:effect on hepatic arterial resistance indices and role of spleen size显示文摘 | Bolognesi M Sacerdoti D Bombonato G | | 0，，03： | 1 |
| 20 | Arterioportal fistulas in patients with liver cirrhosis:usefulness of color Doppler US for screening显示文摘 | Bolognesi M Sacerdoti D Bombonato G | 2000 | Radiology2000，216，3： | 1 |
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