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| 1 | Artemisinin derivatives inhibit epithelial ovarian cancer cells via autophagy-mediated cell cycle arrest显示文摘Epithelial ovarian cancer (EOC)is the most fatal gynecologic malignancy due to its late diagnosis and lack of curative therapy.The antimalaria compound artemisinin and its derivatives,such as artesunate (ART)and dihydroartemisinin (DHA),have proven to be potent anticancer drugs and act through various anticancer mechanisms.To identify novel targets of artemisinin derivatives in EOC cells,we investigated the effects of ART and DHA on SKOV3 and primary EOC cell growth via CCK-8 assay.Both ART and DHA inhibited EOC cell growth.A cell cycle distribution analysis showed that ART and DHA caused G2/M cell cycle arrest.Moreover,ART and DHA induced autophagy in EOC cells,whereas autophagy inhibitors reversed the cell growth inhibition and cell cycle arrest induced by ART and DHA.Western blot analysis showed that ART and DHA also suppressed the cell cycle-related NF-κB-signaling pathway in EOC cells.These data suggest that artemisinin derivatives induce autophagy,block the cell cycle,and inhibit cell growth in EOC cells.Our research provides new targets for artemisinin derivatives for EOC treatment. | Boning Li Shixia Bu Junyan Sun Ying Guo Dongmei Lai | 2018 | Acta Biochimica et Biophysica Sinica2018，50，12： | 11 |
| 2 | Application of Wavelet Transform Modulus Maxima in Raman Distributed Temperature Sensors显示文摘我们建议了并且示威小浪变换模量降噪方法减少的最大值(WTMM ) 温度错误。在这个计划,作文规模被 WTMM 振幅变化在 30 摯汵瑡潩 ? 整档楮畱与分解规模的生长简单地决定吗? | Zongliang WANG Jun CHANG Sasa ZHANG Sha LUO Cuanwu JIA Boning SUN Shuo JIANG Yongning LIU Xiaohui LIU Guangping LV Zhi LIU | 2014 | Photonic Sensors2014，4，2： | 5 |
| 3 | A Method for Eliminating the Impact of Microwave Sweeper Power Fluctuation in BOTDA System显示文摘在 BOTDA 系统的微波 sweeper 电源变化的影响理论上被分析了并且试验性地测试了。并且把探查波浪电源的即时获得与一个新算法作比较为消除这影响认识到探查波浪电源正规化的一个新奇方法被建议。建议方法的原则理论上被描述。并且在我们的新方法和常规方法之间的对比测试被执行。实验结果显示温度精确性有效地被改进从 ? | Shuo Jiang Jun Chang Sasa Zhang Zongliang Wang Sha Luo Boning Sun Xiaohui Liu Yongning Liu Junqiang Tian Chuanwu Jia | 2014 | Photonic Sensors2014，4，1： | 2 |
| 4 | A Four-Element Sensor Array Consisting of Asymmetric Distributed-Feedback Fiber Lasers显示文摘在根据他们的斜坡效率登上顺序安排四不对称的分布式反馈的纤维激光(DFB-FL ) 形成的一个传感器数组系统被建议。产量平坦能有效地用不对称的 DFB-FLs 的申请被改进。尽管它获得了最小的泵力量,最后元素几乎与其它一起有一样的产量。相对紧张噪音(RIN ) 和传感器数组的松驰摆动频率也被分析。某个 DFB-FL 的松驰摆动频率与它在数组的相对位置相关,这被发现。并且某个 DFB-FL 的 RIN 被另外的元素总是在数组影响,它不大概他们的安排是依赖的。 | Pengpeng WANG Jun CHANG Cunguang ZHU Boning SUN Guangping LV Sasa ZHANG Yanjie ZHAO Zhihui SUN Xiaolei ZHANG Gangding PENG | 2014 | Photonic Sensors2014，4，2： | 2 |
| 5 | Analysis and Improvement of SNR in FBG Sensing System显示文摘到噪音比率(SNR ) 的信号的改进有重要意思到察觉到系统的纤维布拉格栅栏(FBG ) 。噪音以及察觉到系统的 FBG 的信号变细的来源被分析。光回来损失(ORL ) 引起的光噪音是在系统的噪音的主要来源,这被发现,并且 coupler 是信号的变细的主要来源。在光纤的元素的 ORL 的原因(例如跳线开关电报,接头和纤维结束) 被介绍。另外,优化纤维的建议光察觉到网络被介绍以便改进 SNR。压制噪音的方法由 FBG 的纤维结束接口引起了,用匹配索引的液体包括,把以在这份报纸提及的方法的纤维辫子弄弯并且劈开是 8 湩敧 ? 楷桴的纤维接口的观点角度吗? | Delong KONG Jun CHANG Peijun GONG Yongning LIU Boning SUN Xiangzhi LIU Pengpeng WANG Zongliang WANG Weijie WANG Yan ZHANG | 2012 | Photonic Sensors2012，2，2： | 2 |
| 6 | Central neurocytoma: a clinicopathological and neuroradiological study显示文摘 | Bo Zhang Boning Luo Zhongwei Zhang Gengxi Sun Jianming Wen | 2004 | Neuroradiology2004，，11： | 1 |
| 7 | Improved genetic distance-based spatial deployment can effectively minimize inbreeding in seed orchard显示文摘Background:Inbreeding in seed orchards is expected to increase with the advancement of breeding cycles,which results in the delivery of crops with suboptimal genetic gain,reduced genetic diversity,and lower seed set.Here,a genetic distance-dependent method for clonal spatial deployment in seed orchards was developed and demonstrated,which reduced the inbreeding levels.The method’s main evaluation parameter of inbreeding is the genetic distance among individuals and the deployment method used an improved adaptive parallel genetic algorithm(IAPGA)based on Python language.Using inbreeding-prone Chinese Mongolian pine breeding population material originating from a single natural population,the proposed method was compared to a traditional orchard design and a distance-based design;namely,complete randomized block(RCB)and optimum neighborhood(ONA)designs,respectively.Results:With the advancement of selective breeding cycles,group separation among orchard related individuals is expected to increase.Based on the genetic distance among individuals,the IAPGA design was superior in significantly reducing the inbreeding level as compared to the two existing designs,confirming its suitability to advanced-generation orchards where relatedness among parents is common.In the 1st,2nd,and mixed generations clonal deployment schemes,the IAPGA design produced lower inbreeding with 87.22%,81.49%,and 87.23%of RCB,and 92.78%,91.30%,and 91.67%of ONA designs,respectively.Conclusions:The IAPGA clonal deployment proposed in this study has the obvious advantage of controlling inbreeding,and it is expected to be used in clonal deployment in seed orchards on a large-scale.Further studies are needed to focus on the actual states of pollen dispersal and mating in seed orchards,and more assumptions should be taken into account for the optimized deployment method. | Boning Yang Haihong Sun Jiandong Qi Shihui Niu Yousry AEl-Kassaby Wei Li | 2020 | Forest Ecosystems2020，7，1： | 1 |
| 8 | Central neurocytoma: a clinicopathological and neuroradiological study显示文摘 | Bo Zhang Boning Luo Zhongwei Zhang Gengxi Sun Jianming Wen | 2004 | Neuroradiology2004，，11： | 1 |
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