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| 1 | Atomic-scale observation of a two-stage oxidation process in Cu2O显示文摘Cu 2 O nanocrystallines (NC ) 直接被观察由在 situ 高分辨率的传播电子显微镜学。一个二阶段的氧化过程被观察:(1 ) 起始的氧化阶段被 Cu 2 经由稳固固体的转变的 O NC,导致一个新中间的 CuO x 阶段的形成。CuO x 阶段的可能的水晶结构被讨论。(2 ) 随后, CuO x 被 layer-by-layer 氧化转变成 CuO。这些结果将在理解铜氧化物的氧化机制帮助并且为改进他们的结构的差异并且利用他们的潜在的工业应用铺平道路。 | Huihui Liu He Zheng Lei Li Huaping Sheng Shuangfeng Jia Fan Cao Xi Liu Boyun Chen Ru Xing Dongshan Zhao Jianbo Wang | 2017 | Nano Research2017，10，7： | 4 |
| 2 | Cholesterol homeostasis regulated by ABCA1 is critical for retinal ganglion cell survival显示文摘Genome-wide association studies have suggested a link between primary open-angle glaucoma and the function of ABCA1.ABCA1 is a key regulator of cholesterol efflux and the biogenesis of high-density lipoprotein(HDL) particles. Here, we showed that the POAG risk allele near ABCA1 attenuated ABCA1 expression in cultured cells. Consistently, POAG patients exhibited lower ABCA1 expression, reduced HDL, and higher cholesterol in white blood cells. Ablation of Abca1 in mice failed to form HDL, leading to elevated cholesterol levels in the retina. Counting retinal ganglion cells(RGCs) by using an artificial intelligence(AI) program revealed that Abca1-deficient mice progressively lost RGCs with age. Single-cell RNA sequencing(scRNA-seq) revealed aberrant oxidative phosphorylation in the Abca1-/-retina, as well as activation of the mTORC1 signaling pathway and suppression of autophagy. Treatment of Abca1-/-mice using atorvastatin reduced the cholesterol level in the retina,thereby improving metabolism and protecting RGCs from death. Collectively, we show that lower ABCA1 expression and lower HDL are risk factors for POAG. Accumulated cholesterol in the Abca1-/-retina causes profound aberrant metabolism, leading to a POAG-like phenotype that can be prevented by atorvastatin. Our findings establish statin use as a preventive treatment for POAG associated with lower ABCA1 expression. | Jialiang Yang Yuhong Chen Tongdan Zou Bai Xue Fang Yang Xiangzhou Wang Yibo Huo Boyun Yan Yuxia Xu Shiyu He Yi Yin Jing Wang Xiong Zhu Lin Zhang Yu Zhou Zhengfu Tai Ping Shuai Man Yu Qian Luo Yilian Cheng Bo Gong Xianjun Zhu Jing Zhang Xinghuai Sun Ying Lin Houbin Zhang Zhenglin Yang | 2023 | Science China(Life Sciences)2023，66，2： | 2 |
| 3 | Hierarchically porous Ni monolith@branch-structured NiCo_2O_4 for high energy density supercapacitors显示文摘A variety of NiCo_2O_4 nanostrucutures ranging from nanowire to nanoplate and branched structures were successfully prepared via a simple hydrothermal process. The experimental results show that NiCo_2O_4 with branched structures possesses the best overall electrochemical performance. The improvement of energy density was explored in terms of hierarchically three-dimensional(3D) metal substrates and a high specific area capacitance, and area energy density is obtained with hierarchically porous Ni monolith synthesized through a controlled combustion procedure. | Mengjie Xu Rongjun Xu Ying Zhao Libao Chen Boyun Huang Weifeng Wei | 2016 | Progress in Natural Science:Materials International2016，26，3： | 0 |
| 4 | Impact of coal mining on groundwater of Luohe Formation in Binchang mining area显示文摘Groundwater of Luohe Formation is the main water source for industrial and agricultural and residential use in Binchang mining area,which is one of the key elements to water conservation coal mining.However,few studies are available to document the enrichment characteristics and influence of underground coal mining on groundwater for the Luohe Formation.This study evaluates the changes of groundwater levels and spring flow caused by mining activities to explore the influence mechanism of coal mining on groundwater by comparatively analysing existing mining data and survey data combined with a series of mapping methods.The results show that the aquifer of Luohe Formation are gradually thinning south-eastwards,disappeared at the mining boundary.In the vertical direction,the lithological structure is distinct,due to alternative sedimentation of meandering river facies and braided river facies.According to the yielding property,the aquifer is divided into three sections,namely,strong water-rich section,medium water-rich section,and weak water-rich section,which are located in northwest and central part,southwest,and the rest part of the mining area,respectively.Mining of Tingnan Coal Mine since 2004 has caused a 3.16 to 194.87 meters drop in groundwater level of Luohe Formation.Until 2015,70.10%of the mining area undergoes a groundwater level drop larger than 10.00 meters.Another influence of underground mining is that the total flow from 34 springs in 8 southern coal mines of the area has decreased by 286.48 L/s with a rate of decrease at 46.95%from 2007 to 2017.The areas that groundwater level falls or spring flow declines are manly located in the mine gob areas.Results also indicate that the ratio of the height of water conducted fracture zone to the mining height in Binchang mining area is between 16.85 and 27.92.This may increase ground water flow in vertical direction,causing a water level in the aquifer system to drop and ultimately decreasing the flow from the springs.The research results will provide data and theoretical support for the protection of groundwater resources and water conservation coal mining of Luohe Formation in Binchang mining area. | Kui Sun Limin Fan Yucheng Xia Cheng Li Jianping Chen Shuai Gao Boyun Wu Jie Peng Yiwei Ji | 2021 | International Journal of Coal Science & Technology2021，8，1： | 0 |
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