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| 1 | Current status of severe fever with thrombocytopenia syndrome in China显示文摘Severe fever with thrombocytopenia syndrome(SFTS) is an emerging infectious disease caused by SFTS virus(SFTSV). SFTSV is associated with a high mortality rate and has been reported in China, South Korea and Japan. SFTSV undergoes rapid changes owing to evolution, gene mutations, and reassortment between different strains of SFTSV. In this review, we summarize the recent cases and general properties of SFTS, focusing on the epidemiology, genetic diversity,clinical features, and diagnostics of SFTSV in China. From 2010 to October 2016, SFTS cases were reported in 23 provinces of China, with increased numbers yearly. Infection and death cases are mainly found in central China, where the Haemaphysalis longicornis ticks are spread. The national average mortality rate of SFTS infection was 5.3%, with higher risk to elder people. The main epidemic period was from May to July, with a peak in May. Thus, SFTS reminds a significant public health problem, and development of prophylactic vaccines and effective antiviral drugs will be highly needed. | Jianbo Zhan Qin Wang Jing Cheng Bing Hu Jing Li Faxian Zhan Yi Song Deyin Guo | 2017 | Virologica Sinica2017，32，1： | 71 |
| 2 | Therapeutic potential of siRNA-mediated combined knockdown of the lAP genes (Livin, XIAP, and Survivin) on human bladder cancer T24 cells显示文摘Livin, apoptosis (XIAP ) 的 X 连接禁止者,和 Survivin 几乎是 apoptosis 的三个著名禁止者在癌症房间只过去表示并且为癌症治疗被认为有势力目标。在现在的学习,我们发现 Livin, XIAP,和 Survivin 同时在膀胱癌症房间被表示。我们推测了那 Livin, XIAP,和 Survivin 可能在房间生长和 apoptosis 上有 synergistic 效果。我们的结果证实了联合那所有这三基因击倒能 synergistically 禁止增长和高级膀胱癌症 T24 房间的转变能力并且把房间 apoptotic 敏感提升到化疗。而且,联合了 Livin, XIAP,和 Survivin 罐头击倒显著地增加许多活跃 caspase-3,活跃 caspase-7,活跃 caspase-9,和 cytosolic Smac。我们的调查结果暗示 Livin, XIAP,和 Survivin 的那联合 silencing 可以是一个有势力为膀胱癌症的多指向的基因治疗。 | Deyong Yang Xishuang Song Jianing Zhang Lin Ye Shujing Wang Xiangyu Che Jianbo Wang Zhiwei Zhang Lina Wang Wei Shi | 2010 | Acta Biochimica et Biophysica Sinica2010，42，2： | 29 |
| 3 | Temperature effect and thermal impact in lithium-ion batteries: A review显示文摘Lithium-ion batteries, with high energy density(up to 705 Wh/L) and power density(up to 10,000 W/L), exhibit high capacity and great working performance. As rechargeable batteries, lithium-ion batteries serve as power sources in various application systems. Temperature, as a critical factor, significantly impacts on the performance of lithium-ion batteries and also limits the application of lithium-ion batteries. Moreover, different temperature conditions result in different adverse effects. Accurate measurement of temperature inside lithiumion batteries and understanding the temperature effects are important for the proper battery management. In this review, we discuss the effects of temperature to lithium-ion batteries at both low and high temperature ranges.The current approaches in monitoring the internal temperature of lithium-ion batteries via both contact and contactless processes are also discussed in the review. | Shuai Ma Modi Jiang Peng Tao Chengyi Song Jianbo Wu Jun Wang Tao Deng Wen Shang | 2018 | Progress in Natural Science:Materials International2018，28，6： | 27 |
| 4 | Fission-track-age records of the Mesozoic tectonic-events in the southwest margin of the Ordos Basin, China显示文摘Based on the analysis of apatite and zircon fission track (FT), the FT age distribution and the peck-ages of the Mesozoic tectonic events in the southwest margin of the Ordos Basin (OB) were discussed. (1) The early event mainly occurred at 213-194 Ma with a peck-age of 205 Ma, and corresponded to the tectonic uplift and the mega-clastic deposit in the southwest OB during the Late Triassic. (2) The middle event included at least two episodes. One was at 165-141 Ma with a peck-age of 150 Ma, and the other was at 115-113 Ma with a peck-age of 114 Ma, corresponding to the over-thrusting and the mega- clastic deposits in the southwest OB during the Late Jurassic to the Early Cretaceous. (3) The late event mainly demonstrated the regional uplifting and included at least two episodes. One was at 100-81 Ma with a peck-age of 90 Ma, and the other was at 66-59 Ma with a peck-age of 63 Ma. Additionally, the relationship analysis of the tectonic event and the mineralizing chronology revealed that the extreme environment of the peck-age event and the subsequent moderate activity could be the key factors of the multiple resources coupling and coexistence in the OB. | CHEN Gang SUN JianBo ZHOU LiFa ZHANG HuiRuo LI XiangPing WANG ZhiWei | 2007 | Science China Earth Sciences2007，50，z2： | 19 |
| 5 | An overview of the use of plastic-film mulching in China to increase crop yield and water-use efficiency显示文摘Since 1990,crop yields have stagnated in many parts of the world,posing a significant challenge to global food security[1].As such;innovative solutions are needed to increase the resource-use efficiency of cropping systems to produce more grains per unit area. | Dongbao Sun Haigang Li Enli Wang Wenqing He Weiping Hao Changrong Yan Yuzhong Li Xurong Mei Yanqing Zhang Zhanxiang Sun Zhikuan Jia Huaiping Zhou Tinglu Fan Xucheng Zhang Qin Liu Fengju Wang Chaochun Zhang Jianbo Shen Qingsuo Wang Fusuo Zhang | 2020 | National Science Review2020，7，10： | 19 |
| 6 | Hydraulic fracture initiation theory for a horizontal well in a coal seam显示文摘A series of experiments were performed to determine rock mechanical parameters related to hydraulic fracturing of coal.The effect of confining pressure and pore pressure on the strength of coal was studied.Experimental results show that the coal seam in the study areas has a relatively low elastic modulus,high Poisson's ratio,high fragility and is easily broken and compressed.The coal seam is considered as a transversely isotropic medium,since the physical properties in the direction of bedding plane and orthogonal to the bedding plane vary markedly.Based on the generalized plane strain model,stress distribution for an arbitrarily orientated wellbore in the coal seam was determined.In a horizontal well,hydraulic fracturing was found to initiate in the coal seam mass due to tensile failure,or from cleats due to shear or tensile failure.For those coal seams with abundant natural cleats,hydraulic fracture initiation can be induced by any of these mechanisms.In this study,hydraulic fracture initiation criteria for a horizontal well in a coal seam were established. | Hou Bing Chen Mian Wang Zheng Yuan Jianbo Liu Ming | 2013 | Petroleum Science2013，10，2： | 18 |
| 7 | Agriculture Green Development: a model for China and the world显示文摘Realizing sustainable development has become a global priority.This holds,in particular,for agriculture.Recently,the United Nations launched the Sustainable Development Goals(SDGs),and the Nineteenth National People’s Congress has delivered a national strategy for sustainable development in China—realizing green development.The overall objective of Agriculture Green Development(AGD)is to coordinate'green'with'development'to realize the transformation of current agriculture with high resource consumption and high environmental costs into a green agriculture and countryside with high productivity,high resource use efficiency and low environmental impact.This is a formidable task,requiring joint efforts of government,farmers,industry,educators and researchers.The innovative concept for AGD will focus on reconstructing the whole crop-animal production and food production-consumption system,with the emphasis on high thresholds for environmental standards and food quality as well as enhanced human well-being.This paper addresses the significance,challenges,framework,pathways and potential solutions for realizing AGD in China,and highlights the potential changes that will lead to a more sustainable agriculture in the future.Proposals include interdisciplinary innovations,whole food chain improvement and regional solutions.The implementation of AGD in China will provide important implications for the countries in developmental transition,and contribute to global sustainable development. | Jianbo SHEN Qichao ZHU Xiaoqiang JIAO Hao YING Hongliang WANG Xin WEN Wen XU Tingyu LI Wenfeng CONG Xuejun LIU Yong HOU Zhenling CUI Oene OENEMA William JDAVIES Fusuo ZHANG | 2020 | Frontiers of Agricultural Science and Engineering2020，7，1： | 18 |
| 8 | An advanced carbon dioxide retrieval algorithm for satellite measurements and its application to GOSAT observations显示文摘An advanced carbon dioxide retrieval algorithm for satellite observations has been developed at the Institute of Atmospheric Physics, Chinese Academy of Sciences. The algorithm is tested using Greenhouse gases Observing SATellite(GOSAT) L1 B data and validated using the Total Column Carbon Observing Network(TCCON) measurements. The retrieved XCO2 agrees well with TCCON measurements in a low bias of 0.15 ppmv and RMSE of 1.48 ppmv, and captured the seasonal variation and increasing of XCO2 in Northern and Southern Hemisphere, respectively, as other measurements. | Dongxu Yang Yi Liu Zhaonan Cai Jianbo Deng Jing Wang Xi Chen | 2015 | Science Bulletin2015，60，23： | 12 |
| 9 | Strain and kinematic vorticity analysis of the Louzidian low-angle ductile shear detachment zone in Chifeng,Inner Mongolia,China显示文摘The Louzidian low-angle ductile shear detachment zone at the south of Chifeng is a SE-dipping, low-angle normal fault system. It is composed mainly of ductile shear zone, ductile-brittle shear zone and brittle fault zone. The ductile shear zone consists of, from bottom to top, mylonitic rocks, protomylonites and mylonites. Finite strain measurement of feldspar strain markers from those rocks using the Rf /φ method shows that strain intensities (Es) of the mylonite at core of the ductile shear zone (Es=0.65-0.96) are higher than those of the mylonitic rocks close to the granite intrusions (Es=0.59-0.62) and of the protomylonites at top of the ductile shear zone (Es= 0.47-0.70), and the strain types of the protomylonites and mylonties are elongate strain and plane-flattening strain, respectively. The kinematic vorticity values (Wk) estimated by the Polar Mohr diagram and the Rigid Grain Net range from 0.81 to 0.90 with an average of 0.85 for the protomylonites, and from 0.53 to 0.80 with 0.66 on average for the mylonites; Wk values of the extensional crenulation cleavage, i.e., C′, estimated by C′ method range from 0.63 to 0.37 with an average of 0.50. The angles between the maximum principal stress and shearing direction determined using the Maximum effective moment criterion evolved from 61° to 69° and to 75°, and finally normal to shearing direction. The results of strain and kinematic vorticity measurements suggest that high strain corresponds to low kinematic vorticity. Kinematic vorticity measurements show that the Louzidian low-angle ductile shear detachment zone is a result of a combination of simple-dominated general shearing at the early stage and pure-dominated general shearing at the late stage. All these, together with isotope geochronology and regional tectonic background, suggest that the Louzidian ductile shear detachment zone resulted from a combination of crust extension and magma intrusion. The model of simple shear at the early stage and pure shear at the late stage in the formation of metamorphic core complex has probably general significance. | LI JianBo WANG Tao OUYANG ZhiXia | 2010 | Science China Earth Sciences2010，53，11： | 12 |
| 10 | Analysis of threshed rice mixture separation through vibration screen using discrete element method显示文摘The discrete element method was utilized to construct three-dimensional discrete element models for the rice mixture,and their motions were analyzed numerically on a planar vibration screening device.The results showed that,after falling onto the vibrating screen surface,the mixture undergoes a reciprocating motion within the same cycle.During the screening process,the mixture undergoes segregation,slides along the screen surface,passes through the screen and then falls.In comparing the movement of grains and shriveled grains,it can be seen that the velocity of shriveled grains experiences cyclical changes,which is consistent with the grains’motion cycle.The impact on grains is shown to be greater than that on shriveled grains,and the average speeds of shriveled grains and grains converge.The curve shows that the screening of repetitive movements has a significant effect on the average velocity of shriveled grains,but also the velocity of shriveled grains and the vibration parameters can be well represented by a fitting equation.It is beneficial for the separation of grains from shriveled grains to choose a greater vibration frequency and screen surface inclination in the range of commonly used. | Li Hua Wang Jinshuang Yuan Jianbo Yin Wenqing Wang Zhiming Qian Youzhang | 2017 | International Journal of Agricultural and Biological Engineering2017，10，6： | 10 |
| 11 | Application of improved active disturbance rejection control algorithm in tilt quad rotor显示文摘The Tilt Quad Rotor(TQR) has complex dynamics characteristics, especially in conversion mode. It is difficult to build the dynamic model of the TQR and the environmental factors have a great influence on it. To solve the problem of control in conversion mode of TQR, this paper carries out the design of the controller based on improved Active Disturbance Rejection Control(ADRC). According to the characteristics of flight in conversion mode, Tracking Differentiator(TD) with explicit model is used to solve the problem of multiple integrals when the system is high-order system. Extended State Observer(ESO) with Radial Basis Function(RBF) neural network is used to estimate and compensate for internal and external uncertainties, and the adaptive sliding mode control in Nonlinear State Error Feedback(NLSEF) is used to improve the response speed of the controller and reduce the parameters which should be tuned. Through the flight control simulation of the TQR, the validity and rationality of the control system are verified. | Zhigang WANG Hong ZHAO Dengyan DUAN Yuanyang JIAO Jianbo LI | 2020 | Chinese Journal of Aeronautics2020，33，6： | 10 |
| 12 | A highly conductive and stretchable wearable liquid metal electronic skin for long-term conformable health monitoring显示文摘Conventional rigid electronics are usually unconformable with soft skins and tend to fail in accurate physiological monitoring and precise treatment. Electronic skins(e-Skins) made by conductive and stretchable materials offer mechanical compliance for fabricating flexible and conformable wearables. Compared to common organic or inorganic conductive materials, gallium-based liquid metals alone own superior conductivity and compliance. Here, we demonstrate a highly conductive and stretchable electronic skin with liquid metal circuits(LMCs) embedded in silicone rubber film, which are functionalized for physiological signals monitoring. Through the designs of serpentine structure, LMCs maintained good electrical conductivity and functionality under over 100% strain. Also, a wearable electrocardiogram(ECG) recording device was fabricated and tested. The device was able to acquire steady signals during real-time measurement of physical activities. The proposed liquid metal e-Skin can be further extended to conformable bio-integrated healthcare devices and intelligent health monitoring networks. | GUO Rui WANG XueLin YU WenZhuo TANG JianBo LIU Jing | 2018 | Science China(Technological Sciences)2018，61，7： | 10 |
| 13 | Anelasticity of twinned CuO nanowires显示文摘CuO nanowires (NW ) 的机械行为被调查由在 situ 传播电子显微镜学。在压缩期间, NW 展出了与高机械的应力联系的高弯曲的能力。有趣地,滞弹性一致地在压力版本以后被观察。进一步的调查显示滞弹性对 CuO NW 内在,尽管 electronbeam 照耀加速形状恢复被证明有能力。机制基于联系双胞胎的原子的合作运动被建议说明这现象。结果提供卓见进 CuO NW 的机械性质,它是为抑制系统的 nanoscale 的有希望的材料。 | Huaping Sheng He Zheng Fan Cao Shujing Wu Lei Li Chun Liu Dongshan Zhao Jianbo Wang | 2015 | Nano Research2015，8，11： | 9 |
| 14 | Fluorescent nanoparticles for chemical and biological sensing显示文摘Fluorescent nanoparticles (NPs), including quantum dots (QDs), dye-doped NPs, and rare earth-based NPs, etc., have been a major focus of research and development during the past decade. The impetus behind such endeavors can be attributed to their unique chemical and optical properties, such as bright fluorescence, high photostability, large Stocks shift and flexible processability. The introduction of fluorescent NPs into analytical chemistry has opened up new venues for fluorescent analysis. In this review, we focus on the developments and analytical applications of fluorescent NPs in the chemical and biological sensing of pH, ions, organic compounds, small biological molecules, nucleic acids, proteins, virus and bacteria. The review also points out the in vitro and in vivo imaging application of fluorescent NPs at the cell and body levels. Meanwhile, the ad- vantages of NPs brought field of sensing and signal transductions are also discussed. | LIU JianBo, YANG XiaoHai, HE XiaoXiao, WANG KeMin, WANG Qing, GUO QiuPing, SHI Hui, HUANG Jin & HUO XiQin State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering, Institute of Biology, Hunan University Key Laboratory for Bio-Nanotechnology and Molecule Engineering of Hunan Province, Changsha 410082, China | 2011 | Science China Chemistry2011，54，8： | 9 |
| 15 | Effect on platelet aggregation activity: extracts from 31 Traditional Chinese Medicines with the property of activating blood and resolving stasis显示文摘OBJECTIVE: To evaluate the anti-platelet aggregation effects of extracts from 31 Traditional Chinese Medicines(TCM) with the property of activating blood and resolving stasis in terms of TCM theory.METHODS: The 31 TCMs extracts were prepared using water, 90% ethanol and ethyl acetate., and the effects on anti-platelet aggregation were tested on a platelet aggregation analyzer in vitro with adenosine 5'-diphosphate, bovine thrombin and arachi-donic acid(AA) as aggregation inducers, respectively. Aspirin was the positive control.RESULTS: Lots of the tested TCMs had inhibitory effects with concentration-dependent manner on platelet aggregations induced by various agonists.Especially, some of the TCMs such as Chuanxiong(Rhizoma Chuanxiong), Yanhusuo(Rhizoma Corydalis Yanhusuo) and Danshen(Radix Salviae Miltiorrhizae) showed good anti-platelet aggregation effect similar or higher than that in positive control group.CONCLUSION: The study provided scientific references that several TCMs such as Chuanxiong(Rhizoma Chuanxiong), Yanhusuo(Rhizoma Corydalis Yanhusuo) and Danshen(Radix Salviae Miltiorrhizae),possess the property of anti-platelet aggregation. | Chen Cen Wang Fengqin Xiao Wen Xia Zhining Hu Guang Wan Jianbo Yang Fengqing | 2017 | Journal of Traditional Chinese Medicine2017，37，1： | 7 |
| 16 | Ginsenoside Rg1 ameliorates bloodebrain barrier disruption and traumatic brain injury via attenuating macrophages derived exosomes miR-21 release显示文摘During the traumatic brain injury(TBI),improved expression of circulatory miR-21 serves as a diagnostic feature.Low levels of exosome-miR-21 in the brain can effectively improve neuroinflammation and bloodebrain barrier(BBB)permeability,reduce nerve apoptosis,restore neural function and ameliorate TBI.We evaluated the role of macrophage derived exosomes-miR-21(M-Exos-miR-21)in disrupting BBB,deteriorating TBI,and Rg1 interventions.IL-1β-induced macrophages(ⅡA)-Exos-miR-21 can activate NF-kB signaling pathway and induce the expressions of MMP-1,-3 and-9 and downregulate the levels of tight junction proteins(TJPs)deteriorating the BBB.Rg1 reduced miR-21-5 p content in ⅡA-Exos(RⅡA-Exos).The interaction of NMIIAe HSP90 controlled the release of Exos-miR-21,this interaction was restricted by Rg1.Rg1 could inhibit the Exos-miR-21 release in peripheral blood flow to brain,enhancing TIMP3 protein expression,MMPs proteolysis,and restricting TJPs degradation thus protected the BBB integrity.Conclusively,Rg1 can improve the cerebrovascular endothelial injury and hold the therapeutic potential against TBI disease. | Kefeng Zhai Hong Duan Wei Wang Siyu Zhao Ghulam Jilany Khan Mengting Wang Yuhan Zhang Kiran Thakur Xuemei Fang Chao Wu Jianbo Xiao Zhaojun Wei | 2021 | Acta Pharmaceutica Sinica B2021，11，11： | 6 |
| 17 | Arsenic trioxide encapsulated liposomes prepared via copper acetate gradient loading method and its antitumor efficiency显示文摘In this study, arsenic trioxide(ATO) was encapsulated in liposomes via copper acetate(Cu(OAc)2) gradients and high entrapment efficiency of over 80% was obtained. The average particle size and the zeta-potential of the liposomes were detected to be 115.1 ± 29.1 nm and-21.97 ± 0.6 m V, respectively. The TEM images showed rod-like precipitates in the inner aqueous phase, which was supposed be due to the formation of insoluble ATO–Cu complex.The in vitro drug release of ATO–Cu liposomes exhibited a sustained release over 72 h, and the release rates decreased with the increase of the p H of release media. Pharmacokinetic and tissue distribution studies of ATO liposomes showed significantly reduced plasma clearance rate, increased AUC0–12h and T1/2, and improved tumor distribution of As compared to iv administration of ATO solution. The anti-tumor effect of ATO loaded liposomes to S180 tumor-bearing mice was significantly improved with a tumor inhibition rate of 61.2%,meanwhile the toxicity of encapsulated ATO was greatly decreased. In conclusion, ATO can be effectively encapsulated into liposomes by remote loading method via Cu(OAc)2 gradients;the co-administration of ATO and Cu(Ⅱ) via liposomal formulation may find wide applications in the treatment of various tumors. | Shaoning Wang Chunxiu Liu Cunyang Wang Jia Ma Hui Xu Jianbo Guo Yihui Deng | 2020 | Asian Journal of Pharmaceutical Sciences2020，15，3： | 6 |
| 18 | Preparation of luminescent CdTe quantum dots doped core-shell nanoparticles and their application in cell recognition显示文摘Based on the reverse microemulsion technique, luminescent quantum dots doped core-shell nanoparticles have been prepared by employing silica as the shell and CdTe quantum dots as the core of the nanoparticles, which have an excellent solubility and dispersibility, especially amine and phosphonate groups have been modified on their surface synchronously. In comparison with CdTe quantum dots, these nanoparticles show superiority in chemical and photo-chemical stability. The quantum dots doped core-shell nanoparticles were successfully linked with lactobionic acid by amine group on it, which was used to recognize living liver cells. | LI Zhaohui WANG Kemin TAN Weihong LI Jun FU Zhiying WANG Yilin LIU Jianbo YANG Xiaohai | 2005 | Chinese Science Bulletin2005，50，16： | 5 |
| 19 | Multilevel profiling and identification of Dalbergia odorifera and Dalbergia stevensonii by FTIR,NMR and GC/MS显示文摘As a rare and valuable wood and herbal material, Dalbergia odorifera is often counterfeited by Dalbergia stevensonii in the market. For the confident chemical identification of D. odorifera and D. stevensonii, the ethanol-benzene extractives are characterized by multiple metabolomics tools, including Fourier transform infrared(FTIR) spectroscopy, nuclear magnetic resonance(NMR), and gas chromatographymass spectrometry(GC/MS). Conventional FTIR spectroscopy, second derivative infrared(SD-IR)spectroscopy and two-dimensional correlation infrared(2D-IR) spectroscopy are combined to interpret the functional groups of the ethanol-benzene extractives. Fingerprint-like characteristics make FTIR a rapid and accurate method to distinguish D. odorifera from D. stevensonii. Chemical differences of the extractives revealed by FTIR methods can be further confirmed by ~1H NMR and ^(13)C NMR. Meanwhile, the volatile compounds in the extractives can be identified by GC/MS. The combination of FTIR, NMR and GC/MS makes it possible to obtain the multiple profiles of the ethanol-benzene extractives, which is essential for the confident chemical identification of D. odorifera and D. stevensonii. | Fang Wang Anmin Huang Xiaoqian Yin Wenshu Wang Jianbo Chen | 2018 | Chinese Chemical Letters2018，29，9： | 5 |
| 20 | Atomistic insight into ordered defect superstructures at novel grain boundaries in CuO nanosheets: From structures to electronic properties显示文摘Determining atomistic structures of grain boundaries (GBs) is essential to understand structure--property interplay in oxides.Here,different GB superstructures in CuO nanosheets,including (111) and (114) twinning boundaries (TBs) and (002)/(223) GB,are investigated.Unlike the lower-energy stoichiometric (111) TB,both experimental and first-principles investigations reveal a severe segregation of Cu and O vacancies and a nonstoichiometric property at (114) TB,which may facilitate ionic transportation and provide space for elemental segregation.More importantly,the calculated electronic structures have shown the increased conductivity as well as the unanticipated magnetism in both (114) TB and (002)/(223) GB.These findings could contribute to the race towards the property-directing structural design by GB engineering. | Lulu Zhao Lei Li Huaping Sheng He Zheng Shuangfeng Jia Weiwei Meng Huihui Liu Fan Cao Huayu Peng Jianbo Wang | 2019 | Nano Research2019，12，5： | 5 |
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