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| 1 | Risk of colon cancer in hereditary non-polyposis colorectal cancer patients as predicted by fuzzy modeling:Influence of smoking显示文摘瞄准:为了调查一个模糊逻辑模型是否能预言肤色,表面的癌症(CRC ) 风险由在世袭 non-polyposis 肤色吸表面的癌症(HNPCC ) 病人产生了。方法:从 Creighton 大学世袭癌症研究所登记的 340 个 HNPCC 失配修理(MMR ) 变化搬运人为当模特儿被选择。年龄依赖者曲线被产生阐明开发 CRC 的概率上的在基因变化(hMLH1 或 hMSH2 ) 之间的联合效果,性,和吸烟地位。结果:在男 hMSH2 变化搬运人的吸烟显著地增加的 CRC 风险(P <
0.05 ) 。hMLH1 变化为男性相对 hMSH2 变化搬运人扩充了 CRC 风险(P <
0.05 ) 。男性们非为 hMLH1 比女性有 CRC 的显著地更高的风险吸烟者(P <
0.05 ) , hMLH1 吸烟者(P <
0.1 ) 并且 hMSH2 吸烟者(P <
0.1 ) 。以在在男性的 hMSH2 的一种剂量依赖者方式的吸烟支持的 CRC (P <
0.05 ) 。有 hMSH2 变化的女性和与 hMLH1 组一起的两性仅仅在广泛的吸烟历史以后表明了吸烟效果(P <
0.05 ) 。结论:由在 HNPCC 病人吸烟的 CRC 提升依赖于基因变化,性和年龄。这些数据证明模糊建模可以启用临床的风险分数的明确的表达,从而允许 CRC 预防策略的 individualization。 | Rhonda M Brand David D Jones Henry T Lynch Randall E Brand Patrice Watson Ramesh Ashwathnayaran Hemant K Roy | 2006 | World Journal of Gastroenterology2006，12，28： | 5 |
| 2 | Neurofibromatosis diagnosed on CT with MR correlation显示文摘 | Arazi-Kleinmann T YM Brand N | 2002 | Eur J Radiol2002，42，1： | 1 |
| 3 | Particle migration after transurethral injection of carbon coated beads for stress urinary incontinence显示文摘 | Pannek J Brands FH Senge T | 2001 | J Urol2001，166，： | 1 |
| 4 | Pigment production by Monascus purpureus in grape waste using {hctorial design 显示文摘 | Silverira S T Daroit D J Brandeli A | 2008 | LWT - Food Science and Technology2008，41，1： | 1 |
| 5 | Pelvic muscle and acetabular contact forces during gait 显示文摘 | PEDERSEN D R BRAND R A DAVY D T | 1997 | J giomech1997，30，9： | 1 |
| 6 | Enzymatic isolation of cells from neonatal calvaria using two purified purified enzymes from clostridium histolyticum显示文摘 | Hefley T J Stern Ph Brand JS | | EXP Cell Res0，149，： | 1 |
| 7 | IL -28A and IL -29 mediateantiproliferative and antiviral signals in intestinal epithelial cellsand murine CMV infection increases colonic IL - 28A expression显示文摘 | Brand S Beigel F 0]szak T | 2005 | Am J Physiol Gastrointest Liver Physiol2005，289，5： | 1 |
| 8 | Hematocrit and the risk of cardiovascular disease-The Framingham Study : a 34-year follow-up 显示文摘 | Gagnon D Zhang T Brand F | 1994 | Am Heart J1994，127，3： | 1 |
| 9 | Two Dimension Photoic- Bandgap Structure Operating at Near Infrared Wavelengths显示文摘 | Krauss T F Rue D L RM Brand S | 1996 | Nature1996，383，： | 1 |
| 10 | Thrombolytic therapy of acute basilar artery occlusion : Variables affecting recanalization and outcome显示文摘 | Brand T Von Kummer R Muller-Kuppers M | 1996 | Stroke1996，27，5： | 1 |
| 11 | Grazing behaviour and diet selection by Dorper sheep显示文摘 | Brand T S | 2000 | Small Ruminant Research2000，36，： | 1 |
| 12 | IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression显示文摘 | Brand S Beigel F Olszak T | 2005 | Am J Physiol Gastrointest Liver Physiol2005，289，5： | 1 |
| 13 | Epidemicacute haemorrhagic conjunctivitis due to Coxsackie virusA24variant in Ghana显示文摘 | Brandful J A Yoshii T Addy E T | 1990 | East Afr Med J1990，67，12： | 1 |
| 14 | The TGF-superfamiiy in myocar- dium: iigand, receptors, transduction and function 显示文摘 | Brand T Schneider M D | 1995 | J Moi Ceii Cardioi1995，27，1： | 1 |
| 15 | Tandemly repeated DNA sequences and centromeric chromosomal regions of Arabidopsis species 显示文摘 | Heslop-Harrison J S Brandes A Schwarzacher T | 2003 | Chrom Res2003，11，3： | 1 |
| 16 | Cancer DNA methylation: molecular mechanisms and clinical implications显示文摘 | McCabe M T Brandes J C Vertino P M | 2009 | Clin Cancer Res2009，15，12： | 1 |
| 17 | Psychological stress as a determinant of protein levels and salivary-induced aggregation of Streptococcus gordonii in human whole saliva 显示文摘 | Bosch J A Brand H S Ligtenberg T J | 1996 | Psychosomatic Medicine1996，58，4： | 1 |
| 18 | The TGF - β superfamily in myocardium, ligands, receptors, transduction and function显示文摘 | Brand T Schneider MD | 1995 | J Mol Cell Cardiol1995，27，1： | 1 |
| 19 | Transforming growth factor - β aignaltransduction显示文摘 | Brand T Schneider MD | 1996 | Circ Res1996，78，2： | 1 |
| 20 | Proto-oncogene expression in porcine myocardium subjected to ischemia and reperfusion显示文摘 | BRAND T SHARMA H S FLEISCHMANN K E | 1992 | Circ Res1992，71，6： | 1 |
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