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| 1 | Video capsule endoscopy vs double-balloon enteroscopy in the diagnosis of small bowel bleeding:A systematic review and metaanalysis显示文摘AIM To compare the diagnostic accuracy of video capsule endoscopy(VCE) and double-balloon enteroscopy(DBE) in cases of obscure gastrointestinal bleeding(OGIB) of vascular origin.METHODS MEDLINE(via PubMed), LILACS(via BVS) and Cochrane/CENTRAL virtual databases were searched for studies dated before 2017. We identified prospective and retrospective studies, including observational, cohort, single-blinded and multicenter studies, comparing VCE and DBE for the diagnosis of OGIB, and data of all the vascular sources of bleeding were collected. All patients were subjected to the same gold standard method. Relevant data were then extracted from each included study using a standardized extraction form. We calculated study variables(sensitivity, specificity, prevalence, positive and negative predictive values and accuracy) and performed a meta-analysis using Meta-Disc software.RESULTS In the per-patient analysis, 17 studies(1477 lesions) were included. We identified3150 exams(1722 VCE and 1428 DBE) in 2043 patients and identified 2248 sources of bleeding, 1467 of which were from vascular lesions. Of these lesions, 864(58.5%) were diagnosed by VCE, and 613(41.5%) were diagnosed by DBE. The pretest probability for bleeding of vascular origin was 54.34%. The sensitivity of DBE was 84%(95%CI: 0.82-0.86; heterogeneity: 78.00%), and the specificity was92%(95%CI: 0.89-0.94; heterogeneity: 92.0%). For DBE, the positive likelihood ratio was 11.29(95%CI: 4.83-26.40; heterogeneity: 91.6%), and the negative likelihood ratio was 0.20(95%CI: 0.15-0.27; heterogeneity: 67.3%). Performing DBE after CE increased the diagnostic yield of vascular lesion by 7%, from 83% to90%.CONCLUSION The diagnostic accuracy of detecting small bowel bleeding from a vascular source is increased with the use of an isolated video capsule endoscope compared with isolated DBE. However, concomitant use increases the detection rate of the bleeding source. | Hélcio Pedrosa Brito Igor Braga Ribeiro Diogo Turiani Hourneaux de Moura Wanderley Marques Bernardo Dalton Marques Chaves Rogério Kuga Ethan Dwane Maahs Robson Kiyoshi Ishida Eduardo Turiani Hourneaux de Moura Eduardo Guimaraes Hourneaux de Moura | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，12： | 10 |
| 2 | Effects of environmental factors, age and genotype on sperm production and semen quality in Bos indicus and Bos taurus AI bulls in Brazil显示文摘 | Brito L F Silva A E Rodriques L H | 2002 | Animal Reproduction Science2002，70，34： | 1 |
| 3 | Ultrasonic Doppler Velocimetry in Liquid Gallium 显示文摘 | Brito D Natal H C Cardin P | 2001 | Experiments in Fluids2001，31，6： | 1 |
| 4 | The luminescent behavior of the steamed EuY zeolite incorporated with vanadium and rare earth passivators显示文摘 | Baugis G Brito H De O | 2001 | Mieroporous and mesoporous materials2001，49，： | 1 |
| 5 | Zero-dimensional model for preliminary design of ablative pulsed plasma Teflon thrusters 显示文摘 | Brito C M Elaskar S A Brito H H | 2004 | Journal of Propulsion and Power2004，20，6： | 1 |
| 6 | Effect of the gamma radiation dose rate on psychrotrophic bacteria, thiobarbituric acid reactive substances, and sensory characteristics of mechanically deboned chicken meat 显示文摘 | Brito P P Azevedo H Cipolli K M Fukuma H T Moutao G B Roque C V Miya N T Pereira J L | 2011 | Journal of Food Science2011，76，2： | 1 |
| 7 | Specification of exception flow in software architecture显示文摘 | Castor F F Brito P H Rubira C M | 2006 | The Journal of System & Software2006，79，10： | 1 |
| 8 | A STR mutation in a heteropaternal twin case 显示文摘 | Geada H Ribeiro T Brito RM | 2001 | Forensic Sci Int2001，123，23： | 1 |
| 9 | Bacterial biodiversity from anthropogenic extreme environments: a hyper-alkaline and hyper- saline industrial residue contaminated by chromium and iron显示文摘 | Brito E M Pion-Castillo H A Guyoneaud R | 2013 | Applied microbiology and biotechnology2013，97，1： | 1 |
| 10 | Sintering and Crystallite Growth of Nanocrystalline Copper Doped Tin Oxide显示文摘 | SANTILLI C V PULCINELLI S H BRITO G E S | 1999 | J Phys Chem B1999，103，14： | 1 |
| 11 | Effects of environmental factors, age and genotype on sperm production and semen quality in Bos indicus and Bos Taurus AI bulls in Brzail 显示文摘 | Brito L F Silva A E Rodrigues L H | 2002 | Anita Reprod Sci2002，70，34： | 1 |
| 12 | Acceptability of male circumcision for the prevention of HIV/AIDS in the Dominican Republic 显示文摘 | Brito MO Caso LM Balbuena H | 2009 | PLoS One2009，4，11： | 1 |
| 13 | Femtosec- ond photon echoes from band to band transitions in GaAs 显示文摘 | Becker P C Fragnito H L Brito Cruz C H | 1988 | Physical Review Letters1988，61，14： | 1 |
| 14 | Emission quantum yield of europium (Ⅲ) mixed complexes with thenoyhriiluoroacetonate and some aromatic ligands 显示文摘 | Silva F R G E Menezes J F S Rocha G B Rocha G B Alves S Brito H F Longo R L Malta O L | 2000 | Journal of Alloys and Compounds2000，303，304： | 1 |
| 15 | 显示文摘 | Kodaia C A Brito H F Malta O L | 2003 | J Lumin2003，101，： | 1 |
| 16 | Zero-dimensional model for preliminary design of ablative pulsed plasma teflon thrusters显示文摘 | Brito C M Elaskar S A Brito H H | 2004 | Journal of Propulsion and Power2004，20，6： | 1 |
| 17 | Effects of environmental factors, age and genotype on sperm production and semen quality in Bos indicus and Bos taurus AI bulls in Brazil显示文摘 | Brito L F C Silva A E D F Rodrigues L H | 2002 | Anita Reprod Sci2002，70，： | 1 |
| 18 | Intestinal barrier function and weight gain in malnourished children taking glutamine supplemented enteral formula显示文摘 | LIMA A A BRITO L F RIBEIRO H B | 2005 | J Pediatr Gastroenterol Nutr2005，40，： | 1 |
| 19 | Photolumineseence Behavior of the Sm3 + and Tb3 + ions Doped into the Gd2 ( WO4 ) 3 Matrix Prepared by the Pechini and Ceramic Methods 显示文摘 | Kodaira C A Brito H F Teotonio E E S | 2004 | Journal of the Brazilian Chemical Society2004，15，6： | 1 |
| 20 | Gastroprotective effect of the ethanolic extract and fractions obtained from Syngonanthus bisulcatus Rul显示文摘 | Batista LM de Almeida ABA de Morais Lima R de Sousa Falc(a)o H Ferreira AL de Pietro Magri L Coelho RG Calvo TR Vilegas W Monteiro Souza Brito AR | | 0，，1： | 1 |
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