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| 1 | Biomass-derived nitrogen-doped hierarchical porous carbon as efficient sulfur host for lithium–sulfur batteries显示文摘Lithium-sulfur(Li-S) battery is a potential energy storage technology with high energy density and low cost. However, the gap between theoretical expectation and practical performance limits its wide implementation. Herein, we report a nitrogen-doped porous carbon derived from biomass pomelo peel as sulfur host material for Li-S batteries. The hierarchical porous architecture and the polar surface introduced by N-doping render a favorable combination of physical and chemical sulfur confinements as well as an expedite electron/ion transfer, thus contributing to a facilitated and stabilized sulfur electrochemistry. As a result, the corresponding sulfur composite electrodes exhibit an ultrahigh initial capacity of 1534.6 mAh g^-1, high coulombic efficiency over 98% upon 300 cycles, and decent rate capability up to 2 C. This work provides an economical and effective strategy for the fabrication of advanced carbonaceous sulfur host material as well as the significant improvement of Li-S battery performance. | Qinghuiqiang Xiao Gaoran Li Minjie Li Ruiping Liu Haibo Li Pengfei Ren Yue Dong Ming Feng Zhongwei Chen | 2020 | Journal of Energy Chemistry2020，29，5： | 15 |
| 2 | Toxicity of the brominated flame retardant tris-(2,3-dibromopropyl) isocyanurate in zebrafish (Danio rerio)显示文摘Tris-(2,3-dibromopropyl) isocyanurate (TBC) is a heterocyclic brominated flame retardant that was recently detected in the environment in China.TBC is semi-volatile and can accumulate in the lipid of some species,but little is known about its effect on aquatic organisms.We exposed adult zebrafish to 0,0.25,1 and 4mg/L TBC for 28 d and measured the effect on survival,growth,histopathology,hormone levels,enzyme activity,and gene expression.TBC exposure had no effect on survival or growth.We observed significant damage to the liver and gill,including hepatocellular swelling and fatty degeneration in the liver as well as proliferation and edema of epithelial cells in the gills.In addition,exposure to 4mg/L TBC induced proliferation of goblet cells in the intestine of both sexes,acellular areas in the testis,and thinly scattered vitellogenic granules in vitellogenic oocytes.TBC exposure had no effect on the levels of thyroid hormones,testosterone,estradiol,liver superoxide dismutase activity,malondialdehyde content,and brain cholinesterase activity.By contrast,hepatic vitellogenin and cytochrome P4501A gene expression was significantly down-regulated in both male and female zebrafish in response to TBC exposure.Our results suggest that exposure to TBC causes a variety of potential reproductive and endocrine toxic effects. | ZHANG Xu LI Juan CHEN MinJie WU Le ZHANG Chi ZHANG Jie ZHOU QunFang LIANG Yong | 2011 | Chinese Science Bulletin2011，56，15： | 13 |
| 3 | Impact of dissolved organic matter on the photolysis of the ionizable antibiotic norfloxacin显示文摘Norfloxacin(NOR), an ionizable antibiotic frequently used in the aquaculture industry, has aroused public concern due to its persistence, bacterial resistance, and environmental ubiquity.Therefore, we investigated the photolysis of different species of NOR and the impact of a ubiquitous component of natural water — dissolved organic matter(DOM), which has a special photochemical activity and normally acts as a sensitizer or inhibiter in the photolysis of diverse organics; furthermore, scavenging experiments combined with electron paramagnetic resonance(EPR) were performed to evaluate the transformation of NOR in water. The results demonstated that NOR underwent direct photolysis and self-sensitized photolysis via hydroxyl radical(U OH) and singlet oxygen(1O2) based on the scavenging experiments. In addition, DOM was found to influence the photolysis of different NOR species, and its impact was related to the concentration of DOM and type of NOR species. Photolysis of cationic NOR was photosensitized by DOM at low concentration, while zwitterionic and anionic NOR were photoinhibited by DOM, where quenching of U OH predominated according to EPR experiments, accompanied by possible participation of excited triplet-state NOR and1O2. Photo-intermediate identification of different NOR species in solutions with/without DOM indicated that NOR underwent different photodegradation pathways including dechlorination, cleavage of the piperazine side chain and photooxidation, and DOM had little impact on the distribution but influenced the concentration evolution of photolysis intermediates. The results implied that for accurate ecological risk assessment of emerging ionizable pollutants, the impact of DOM on the environmental photochemical behavior of all dissociated species should not be ignored. | Chen Liang Huimin Zhao Minjie Deng Xie Quan Shuo Chen Hua Wang | 2015 | Journal of Environmental Sciences2015，27，1： | 11 |
| 4 | The Chinese Hα Solar Explorer(CHASE) mission: An overview显示文摘The Chinese Hα Solar Explorer(CHASE), dubbed “Xihe”—Goddess of the Sun, was launched on October 14, 2021 as the first solar space mission of China National Space Administration(CNSA). The CHASE mission is designed to test a newly developed satellite platform and to acquire the spectroscopic observations in the Hα waveband. The Hα Imaging Spectrograph(HIS)is the scientific payload of the CHASE satellite. It consists of two observational modes: raster scanning mode and continuum imaging mode. The raster scanning mode obtains full-Sun or region-of-interest spectral images from 6559.7 to 6565.9 ? and from 6567.8 to 6570.6 ? with 0.024 ? pixel spectral resolution and 1 min temporal resolution. The continuum imaging mode obtains photospheric images in continuum around 6689 ? with the full width at half maximum of 13.4 ?. The CHASE mission will advance our understanding of the dynamics of solar activity in the photosphere and chromosphere. In this paper, we present an overview of the CHASE mission including the scientific objectives, HIS instrument overview, data calibration flow, and first results of on-orbit observations. | Chuan Li Cheng Fang Zhen Li MingDe Ding PengFei Chen Ye Qiu Wei You Yuan Yuan MinJie An HongJiang Tao XianSheng Li Zhe Chen Qiang Liu Gui Mei Liang Yang Wei Zhang WeiQiang Cheng JianXin Chen ChangYa Chen Qiang Gu QingLong Huang MingXing Liu ChengShan Han HongWei Xin ChangZheng Chen YiWei Ni WenBo Wang ShiHao Rao HaiTang Li Xi Lu Wei Wang Jun Lin YiXian Jiang LingJie Meng Jian Zhao | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，8： | 7 |
| 5 | Sulfur nanoparticles encapsulated in reduced graphene oxide nanotubes for flexible lithium-sulfur batteries显示文摘灵活电子设备的快速的开发正在支持灵活精力存储设备的设计。锂硫(Li-S ) 电池为高精力密度精力存储设备被认为候选人同样有希望。因此,灵活 Li-S 电池被需要。在这研究,我们制作了独立减少的 graphene 氧化物 nanotubes 的合成电影由压 RGONTs@S 合成泡沫包了硫 nanoparticles (RGONTs@S ) ,它被把冷熄灭与 freeze-drying 和一个随后的减小过程相结合综合。这些 RGONTs@S 合成电影能是服务自食其力为没有另外的文件夹和传导性的代理人的 Li-S 电池的阴极。他们的互连的管状的结构允许在整个网络和帮助的容易的电子运输限制在控告 / 解除过程期间生产的 polysulfides。作为结果, RGONTs@S 合成电影展出了一个高起始的特定的能力,显著骑车稳定性,和优秀的率能力。更重要地, RGONTs@S 合成电影能在灵活 Li-S 电池用作电极。作为概念的一个证明,软包裹的 Li-S 电池用这些电极被装配,他们以不同弯曲状态显示了稳定的电气化学的性能。 | Kena Chen Jun Cao Qiongqiong Lu Qingrong Wang Minjie Yao Mingming Han Zhiqiang Niu Jun Chen | 2018 | Nano Research2018，11，3： | 6 |
| 6 | GATA family members as inducers for cellular reprogramming to pluripotency显示文摘GATA 蛋白质家庭的成员在系说明和 transdifferentiation 起重要作用。以前的报告证明 GATA 蛋白质家庭罐头的一些成员也由代替 Oct4 在体的房间导致 pluripotency,一个关键联系 pluripotency 的因素。然而,连接指定系的暗示的机制和 pluripotency 的激活留下逃犯。这里,我们报导所有 GATA 家庭成员能代替让 Oct4 导致 pluripotency。我们发现 GATA 家庭的所有成员能禁止 overrepresented ectodermal 系基因,它与以前的报告显示不同指定系的力量的平衡为 pluripotency 的恢复是重要的一致。一根保存锌手指在 C 终点的 DNA 有约束力的领域是批评的让 GATA 家庭导致 pluripotency。用 RNA-seq 和 ChIP-seq,我们决定 pluripotency 相关的基因 Sall4 在 reprogramming 期间是 GATA 家庭成员的一个直接目标并且用作连接指定系的 GATA 家庭到 pluripotency 电路的一座桥。因此, GATA 家庭是所有成员能作为 reprogramming 进程的 inducers 工作并且能代替 Oct4 的第一个蛋白质家庭。我们的结果建议在 reprogramming 的 GATA 家庭的角色被低估了并且 GATA 家庭可以担任房间命运变换的一个重要调停人。 | Jian Shu Ke Zhang Minjie Zhang Yao Sida Shao Fengxia Du Caiyun Yang Wenhan Chen Chen Wu Weifeng Yang Yingli Sun Hongkui Deng | 2015 | Cell Research2015，25，2： | 5 |
| 7 | Doped, conductive SiO_(2) nanoparticles for large microwave absorption显示文摘Although many materials have been studied for the purpose of microwave absorption,SiO_(2) has never been reported as a good candidate.In this study,we present for the first time that doped,microwave conductive SiO_(2) nanoparticles can possess an excellent microwave absorbing performance.A large microwave reflection loss(RL)of−55.09 dB can be obtained.The large microwave absorption originates mainly from electrical relaxation rather than the magnetic relaxation of the incoming microwave field.The electrical relaxation is attributed to a large electrical conductivity that is enabled by the incorporation of heterogeneous(N,C and Cl)atoms.The removal of the magnetic susceptibility only results in a negligible influence of the microwave absorption.In contrast,the removal of the heterogeneous atoms leads to a large decrease in the electrical conductivity and microwave absorption performance.Meanwhile,the microwave absorption characteristics can be largely adjusted with a change of the thickness,which provides large flexibility for various microwave absorption applications. | Michael Green Zhanqiang Liu Peng Xiang Yan Liu Minjie Zhou Xinyu Tan Fuqiang Huang Lei Liu Xiaobo Chen | 2018 | Light(Science & Applications)2018，7，1： | 4 |
| 8 | Cloning and Expression Analysis of Citrus Genes Cs GH3.1 and Cs GH3.6Responding to Xanthomonas axonopodis pv. citri Infection显示文摘To study the functions of the early auxin-responsive genes Cs GH3.1 and Cs GH3.6 in citrus resistance against canker disease, we cloned Cs GH3.1and Cs GH3.6 in ‘Newhall' Navel Orange(Citrus sinensis Osbeck). They are 1 797 bp and 1 887 bp and encode 598 and 629 amino acids, respectively. In vitro mature leaves from susceptible ‘Newhall' and resistant Calamondin(C. madurensis) were inoculated by a Xanthomonas axonopodis pv. citri(Xac) bacterial suspension, and expression of Cs GH3.1 and Cs GH3.6 in the two varieties were analyzed using quantitative real-time PCR(q RT-PCR). ‘Newhall' leaves were treated with different hormones for 3 days, inoculated by Xac bacterial suspension, and then the symptoms in these leaves were investigated. We used q RT-PCR to analyze the effect of different hormones on Cs GH3.1 and Cs GH3.6 expression in ‘Newhall'leaves. The expression levels of both Cs GH3.1 and Cs GH3.6 were significantly induced by Xac in ‘Newhall' leaves, compared with levels in Calamondin leaves. 1-naphthy acetic acid(NAA) increased the hypertrophy of infection sites in ‘Newhall' leaves, while naphthyl-phthalamic acid(NPA)had no visible effect on lesion development. NAA hormone greatly improved expression of Cs GH3.1 in ‘Newhall', but not Cs GH3.6. These results indicate that the auxin primary-response gene Cs GH3.1 plays an important role in citrus susceptibility to Xac. | CHEN Min HE Yongrui XU Lanzhen PENG Aihong LEI Tiangang YAO Lixiao LI Qiang ZHOU Pengfei BAI Xiaojing DUAN Minjie JIANG Xueyou JIA Ruirui ZOU Xiuping CHEN Shanchun | 2016 | Horticultural Plant Journal2016，2，4： | 4 |
| 9 | Reinforced polysulfide barrier by g-C_(3)N_(4)/CNT composite towards superior lithium-sulfur batteries显示文摘The notorious shuttle effect has long been obstructing lithium-sulfur(Li-S) batteries from yielding the expected high energy density and long lifespan.Herein,we develop a multifunctional polysulfide barrier reinforced by the graphitic carbon nitride/carbon nanotube(g-C_3 N_4/CNT) composite toward inhibited shuttling behavior and improved battery performance.The obtained g-C_3 N_4 delivers a unique spongelike architecture with massive ion transfer pathways and fully exposed active interfaces,while the abundant C-N heteroatomic structures impose strong chemical immobilization toward lithium polysulfides.Combined with the highly conductive agent,the g-C_3 N_4/CNT reinforced separator is endowed with great capability of confining and reutilizing the active sulfur within the cathode,thus contributing to an efficient and stable sulfur electrochemistry.Benefiting from these synergistic attributes,Li-S cells based on g-C_3 N_4/CNT separator exhibit an excellent cyclability with a minimum decay rate of 0.03% per cycle over 500 cycles and decent rate capability up to 2 C.Moreover,a high areal capacity of 7.69 mAh cm^(-2)can be achieved under a raised sulfur loading up to 10.1 mg cm^(-2).demonstrating a facile and efficient pathway toward superior Li-S batteries. | Xiangliang Wang Gaoran Li Minjie Li Ruiping Liu Haibo Li Tengyu Li Mingzhu Sun Yirui Deng Ming Feng Zhongwei Chen | 2021 | Journal of Energy Chemistry2021，30，2： | 4 |
| 10 | DICER1 regulates antibacterial function of epididymis by modulating transcription of p-defensins显示文摘DICER1 is a key enzyme responsible for the maturation of microRNAs. Recent evidences suggested that DICER1 and microRNAs expressed in epididymis were involved in the control of male fertility. However, the exact mechanism remains to be elucidated. Here, we created a mouse line by targeted disruption of Dicerl gene in the principal cells of distal caput epididymis. Our data indicated that a set of β-defensin genes were downregulated by DICER1 rather than by microRNAs. Moreover, DICER1 was significantly enriched in the promoter of β-defensin gene and controlled transcription. Besides, the antibacterial ability of the adult epididymis significantly declined upon Dicerl deletion both in vitro and in vivo. And a higher incidence of reproductive defect was observed in middle-aged Dicerl^-|- males. These results suggest that DICER1 plays an important role in transcription of β-defensin genes, which are associated with the natural antibacterial properties in a microRNA-independent manner, and further impacts the male fertility. | Chunhua Tang Minjie Ni Shengsong Xie Yao Zhang Chaobao Zhang Zimei Ni Chen Chu Ligang Wu Yuchuan Zhou Yonglian Zhang | 2019 | Journal of Molecular Cell Biology2019，11，5： | 3 |
| 11 | A male-ABCD algorithm for hepatocellular carcinoma risk prediction in HBs Ag carriers显示文摘Objective: Hepatocellular carcinoma(HCC) development among hepatitis B surface antigen(HBs Ag) carriers shows gender disparity, influenced by underlying liver diseases that display variations in laboratory tests. We aimed to construct a risk-stratified HCC prediction model for HBs Ag-positive male adults.Methods: HBs Ag-positive males of 35-69 years old(N=6,153) were included from a multi-center populationbased liver cancer screening study. Randomly, three centers were set as training, the other three centers as validation. Within 2 years since initiation, we administrated at least two rounds of HCC screening using Bultrasonography and α-fetoprotein(AFP). We used logistic regression models to determine potential risk factors,built and examined the operating characteristics of a point-based algorithm for HCC risk prediction.Results: With 2 years of follow-up, 302 HCC cases were diagnosed. A male-ABCD algorithm was constructed including participant's age, blood levels of GGT(γ-glutamyl-transpeptidase), counts of platelets, white cells,concentration of DCP(des-γ-carboxy-prothrombin) and AFP, with scores ranging from 0 to 18.3. The area under receiver operating characteristic was 0.91(0.90-0.93), larger than existing models. At 1.5 points of risk score,26.10% of the participants in training cohort and 14.94% in validation cohort were recognized at low risk, with sensitivity of identifying HCC remained 100%. At 2.5 points, 46.51% of the participants in training cohort and 33.68% in validation cohort were recognized at low risk with 99.06% and 97.78% of sensitivity, respectively. At 4.5 points, only 20.86% of participants in training cohort and 23.73% in validation cohort were recognized at high risk,with positive prediction value of 22.85% and 12.35%, respectively.Conclusions: Male-ABCD algorithm identified individual's risk for HCC occurrence within short term for their HCC precision surveillance. | Yuting Wang Minjie Wang He Li Kun Chen Hongmei Zeng Xinyu Bi Zheng Zhu Yuchen Jiao Yong Wang Jian Zhu Hui Zhao Xiang Liu Chunyun Dai Chunsun Fan Can Zhao Deyin Guo Hong Zhao Jianguo Zhou Dongmei Wang Zhiyuan Wu Xinming Zhao Wei Cui Xuehong Zhang Jianqiang Cai Wanqing Chen Chunfeng Qu | 2021 | Chinese Journal of Cancer Research2021，33，3： | 3 |
| 12 | Regulation of impedance matching feature and electronic structure of nitrogen-doped carbon nanotubes for high-performance electromagnetic wave absorption显示文摘In this study,we developed a facile method to fabricate three-dimensional(3D)structures composed of FeNi alloy nanoparticles encapsulated in N-doped carbon nanotubes that grafted on the SiO_(2) spheres(Fe_(x)Ni_(y)@NCNT@SiO_(2))for electromagnetic wave(EMW)absorption.The experimental results suggest that the impedance matching characteristic can be tuned by the introduction of SiO_(2) spheres in the 3D structure.Density functional theory(DFT)calculations showed that the introduction of Ni improved the polarization and conductive losses of the Fe_(x)Ni_(y)@NCNT@SiO_(2).As a result,the optimal 3D structure exhibits excellent EMW absorption property with a reflection loss and effective absorption bandwidth are-49.39 dB and 4.32 GHz,respectively,even though the matching thickness is only 1.6 mm,superior to most magnetic carbon-based composites.Thus,our current approach opens up an effective way to the development of low-cost,high-performance EMW absorbers. | Fenghui Cao Jia Xu Minjie Liu Feng Yan Qiuyun Ouyang Xitian Zhang Xiaoli Zhang Yujin Chen | 2022 | Journal of Materials Science & Technology2022，，13： | 3 |
| 13 | WiFi CSI Gesture Recognition Based on Parallel LSTM-FCN Deep Space-Time Neural Network显示文摘In this study,we developed a system based on deep space–time neural networks for gesture recognition.When users change or the number of gesture categories increases,the accuracy of gesture recognition decreases considerably because most gesture recognition systems cannot accommodate both user differentiation and gesture diversity.To overcome the limitations of existing methods,we designed a onedimensional parallel long short-term memory–fully convolutional network(LSTM–FCN)model to extract gesture features of different dimensions.LSTM can learn complex time dynamic information,whereas FCN can predict gestures efficiently by extracting the deep,abstract features of gestures in the spatial dimension.In the experiment,50 types of gestures of five users were collected and evaluated.The experimental results demonstrate the effectiveness of this system and robustness to various gestures and individual changes.Statistical analysis of the recognition results indicated that an average accuracy of approximately 98.9% was achieved. | Zhiling Tang Qianqian Liu Minjie Wu Wenjing Chen Jingwen Huang | 2021 | China Communications2021，18，3： | 2 |
| 14 | Different self-assembly behaviors of mono-modified β-cyclodextrin substituted by benzoic acid derivatives显示文摘The mono-modified β-cyclodextrin derivative,6-O-(4-aminobenzoyl)-β-cyclodextrin(1) ,was synthesized and characterized. We compared its self-assembling behavior with structurally related β-cyclodextrin derivative,6-O-(4-hydroxybenzoyl)-βcyclodextrin(2) ,in aqueous solution and in the solid state using NMR spectroscopy and single crystal X-ray structure analysis. The two complexes displayed different self-assembling behaviors.Complex 1 formed a head-to-tail helical columnar superstructure in which the substituent group penetrated deeply into the hydrophobic cavity of the adjacent β-cyclodextrin from the second side and aligned along the screw axis,whereas 2 exhibited a channel superstructure with a tail-to-tail dimer as the repeating motif.Further NMR studies in aqueous solution supported the result of the solid state.The influence of substituent groups on the self-assembly behavior was examined in mono-modified β-cyclodextrins by means of substituting an amino group for a hydroxyl group,which indicates that the weak intermolecular interaction is a critical factor in determining the self-assembling behavior. | Zhi Fan MinJie Guo Bin Dong ChunHua Diao ZuoLiang Jing Xin Chen | 2010 | Science China Chemistry2010，53，5： | 2 |
| 15 | A facile self-catalyzed CVD method to synthesize Fe3C/N-doped carbon nanofibers as lithium storage anode with improved rate capability and cyclability显示文摘Uniform Fe3 C/N-doped carbon nanofibers were successfully synthesized through a facile self-catalyzed CVD method by using acetylene as carbon source and Fe3O4 as iron source and autocatalytic template for the reaction under moderate preparation conditions. The experimental and theoretical calculation results demonstrate that Fe3 C can improve the lithium storage performance of carbon nanofibers. Besides, the addition of PPy can not only control the growth rate of carbon fibers but also help to form uniform carbon fibers. As a result, the obtained Fe3 C/N-doped carbon nanofiber composites display favorable electrochemical performance as an anode for lithium-ion batteries, which including satisfactory rate performance of 402 m A h g-1 under 1.2 Ag-1, and good cycling stability of 502.3 m A h g-1 under 200 m Ag-1 over 400 cycles. The introduction of Fe3 C species and the uniform carbon fiber morphology are responsible for the long-cycling and high rate performance of materials. | Liang Chen Zhi Li Gangyong Li Minjie Zhou Binhong He Jie Ouyang Wenyuan Xu Wei Wang Zhaohui Hou | 2020 | Journal of Materials Science & Technology2020，44，9： | 2 |
| 16 | Efficient oxidation of ethylbenzene catalyzed by cobalt zeolitic imidazolate framework ZIF-67 and NHPI显示文摘Efficient catalytic oxidation of ethylbenzene to acetophenone was realized using the catalytic system of cobalt zeolitic imidazolate framework ZIF-67/N-hydroxyphthalimide(NHPI) under mild conditions. 95.2% conversion of ethylbenzene with 90.3% selectivity to acetophenone could be obtained at 373 K under 0.3 MPa O2 for 9 h. The results show that there exists synergetic effect between ZIF-67 and NHPI. 1-Phenylethyl hydroperoxide(PEHP) was generated via a radical process involving the hydrogen abstraction from ethylbenzene by phthalimide N-oxyl, and subsequently effectively decomposed to acetophenone by ZIF-67. | Hongyan Li Hong Ma Xinhong Wang Jin Gao Chen Chen Song Shi Minjie Qu Na Feng Jie Xu | 2014 | Journal of Energy Chemistry2014，23，6： | 2 |
| 17 | Activated carbon felts with exfoliated graphene nanosheets for flexible all-solid-state supercapacitors显示文摘The recent development of portable electronics promotes the growing demand for flexible energy storage devices. Supercapacitors are promising candidates due to their high power density. Therefore, flexible supercapacitors are desired. Here, the porous activated carbon felts(ACFs) with exfoliated graphene nanosheets and rich oxygen-containing groups were fabricated by a facile thermal treatment strategy.Such ACFs can act as the flexible electrodes of all-solid-state supercapacitors directly without the use of binder and conductive materials. They exhibit excellent electrochemical properties, such as high specific areal capacitance, superior rate ability and long-term cycling stability. Moreover, the fabricated flexible all-solid-state supercapacitors based on ACFs deliver stable electrochemical performance under different bending states. | Zifang Zhao Xiaojun Wang Minjie Yao Lili Liu Zhiqiang Niu Jun Chen | 2019 | Chinese Chemical Letters2019，30，4： | 2 |
| 18 | Factors Affecting Kyphotic Angle Reduction in Osteoporotic Vertebral Compression Fractures with Kyphoplasty显示文摘 | Shen Minjie Wang Heng Chen Guangdong Gan Minfeng Yuan Quan Wang Zhidong Liu Ling Yang Huilin | 2013 | Orthopedics (Online)2013，，4： | 2 |
| 19 | Rice SPL10 positively regulates trichome development through expression of HL6 and auxin-related genes显示文摘Trichomes function in plant defenses against biotic and abiotic stresses;examination of glabrous lines,which lack trichomes,has revealed key aspects of trichome development and function.Tests of allelism in 51 glabrous rice(Oryza sativa)accessions collected worldwide identified OsSPL10 and OsWOX3B as regulators of trichome development in rice.Here,we report that OsSPL10 acts as a transcriptional regulator controlling trichome development.Haplotype and transient expression analyses revealed that variation in the approximately 700-bp OsSPL10 promoter region is the primary cause of the glabrous phenotype in the indica cultivar WD-17993.Disruption of OsSPL10 by genome editing decreased leaf trichome density and length in the NIL-HL6 background.Plants with genotype OsSPL10^(WD-17993)/HL6 generated by crossing WD-17993 with NIL-HL6 also had fewer trichomes in the glumes.HAIRY LEAF6(HL6)encodes another transcription factor that regulates trichome initiation and elongation,and OsSPL10 directly binds to the HL6 promoter to regulate its expression.Moreover,the transcript levels of auxin-related genes,such as OsYUCCA5 and OsPIN-FORMED1b,were altered in OsSPL10 overexpression and RNAi transgenic lines.Feeding tests using locusts(Locusta migratoria)demonstrated that non-glandular trichomes affect feeding by this herbivore.Our findings provide a molecular framework for trichome development and an ecological perspective on trichome functions. | Jinjie Li Bo Tang Yingxiu Li Chenguang Li Minjie Guo Haiyang Chen Shichen Han Jin Li Qijin Lou Wenqiang Sun Peng Wang Haifeng Guo Wei Ye Zhanying Zhang Hongliang Zhang Sibin Yu Long Zhang Zichao Li | 2021 | Journal of Integrative Plant Biology2021，63，8： | 2 |
| 20 | Rho-Associated Kinase Inhibitors Promote Microglial Uptake Via the ERK Signaling Pathway显示文摘Microglia are immunocompetent cells in the central nervous system that take up tissue debris and pathogens.Rho-associated kinase(ROCK) has been identified as an important regulator of uptake, proliferation, secretion, and differentiation in a number of cell types. Although ROCK plays critical roles in the microglial secretion of inflammatory factors,migration, and morphology, its effects on microglial uptake activity have not been well characterized. In the present study,we found that treatment of BV2 microglia and primary microglia with the ROCK inhibitors Y27632 and fasudil increased uptake activity and was associated with morphological changes. Furthermore, western blots showed that this increase in uptake activity was mediated through the extracellular-signal-regulated kinase(ERK) signaling cascade, indicating the importance of ROCK in regulating microglial uptake activity. | Peicai Fu Ronghua Tang Zhiyuan Yu Caihong Li Xue Chen Minjie Xie Wei Wang Xiang Luo | 2016 | Neuroscience Bulletin2016，32，1： | 2 |
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