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| 1 | Chinese consensus guidelines for diagnosis and management of gastrointestinal stromal tumor显示文摘In order to further promote the standardization of diagnosis and treatment of gastrointestinal stromal tumor(GIST) in China, the members of Chinese Society of Clinical Oncology(CSCO) Expert Committee on GIST thoroughly discussed the key contents of the consensus guidelines, and voted on the controversial issue. In final, the Chinese consensus guidelines for the diagnosis and management of GIST(2017 edition) was formed on the basis of 2013 edition consensus guidelines, which is hereby announced. The consensus included the pathological diagnosis,recurrence risk classification evaluation, targeted agent therapy, surgery and principles of surveillance of GIST. | jian li yingjiang ye jian wang bo zhang shukui qin yingqiang shi yulong he xiaobo liang xiufeng liu ye zhou xin wu xinhua zhang ming wang zhidong gao tianlong lin hui cao lin shen | 2017 | Chinese Journal of Cancer Research2017，29，4： | 104 |
| 2 | A new solution for topology optimization problems with multiple loads:The guide-weight method显示文摘The guide-weight method is introduced to solve two kinds of topology optimization problems with multiple loads in this paper.The guide-weight method and its Lagrange multipliers' solution methods are presented first,and the Lagrange multipliers' soution method of problems with multiple constraints is improved by the dual method.Then the iterative formulas of the guide-weight method for topology optimization problems of minimum compliance and minimum weight are derived and coresponding numerical examples are calculated.The results of the examples exhibits that when the guide-weight method is used to solve topology optimization problems with multiple loads,it works very well with simple iterative formulas,and has fast convergence and good solution.After comparison with the results calculated by the SCP method in Ansys,one can conclude that the guide-weight method is an effective method and it provides a new way for solving topology optimization problems. | LIU XinJun LI ZhiDong CHEN Xiang | 2011 | Science China(Technological Sciences)2011，54，6： | 22 |
| 3 | Stage-progressive distribution pattern of the Lungmachi black graptolitic shales from Guizhou to Chongqing, Central China显示文摘The Lungmachi Formation is widely distributed in Guizhou, Chongqing and the adjacent area. It is important for the study of Silurian biostratigraphy and shale-gas investigation. Based on those biostratigraphically well-studied sections from Guiyang to Huayingshan, we reveal the stage-progressive distribution pattern of the Lungmachi black shales. The distribution of the Lungmachi black shales in the studying area can be subdivided into four geographic belts from the south to the north,reflecting the joint effect of regional and global environmental changes. The graptolite depth zonation model was adopted herein to infer the water depth of major graptolite assemblages from the black shales. The changes in the water depth indicate two major stages. The first stage is named the transgressive distribution stage which ranged from the Persculptograptus persculptus Biozone(LM1, upper Hirnantian) to the Coronograptus cyphus Biozone(LM5, upper Rhuddanian), an interval mostly controlled by global sea-level rise. The second stage, ranging from the Demirastrites triangulatus Biozone(LM6, lower Aeronian) to the Spirograptus guerichi Biozone(LM9, lower Telychian), is named the regressive shrinking stage, during which the black shales were gradually replaced by mixed-facies or carbonate sediments from the south to the north, representing the effects of the persistent uplifting of the Central Guizhou Oldland. | CHEN Xu FAN JunXuan WANG WenHui WANG HongYan NIE HaiKuan SHI XueWen WEN ZhiDong CHEN DongYang LI WenJie | 2017 | Science China Earth Sciences2017，60，6： | 23 |
| 4 | 叶尔羌灌区冬小麦生育期 SPAC 水热传输的模拟研究显示文摘本文应用土壤水动力学、微气象学和能量平衡原理,建立了作物生育期土壤植物大气连续体(SPAC)的水热迁移和转化模型,并采用全隐式有限差分方法进行离散,通过自动调节计算步长和反复迭代等方法设计了数值模拟程序.运用本模型对新疆叶尔羌河流域地下水均衡场1995年3月~6月冬小麦返青至成熟期的田间水热状况进行了模拟.结果证明,该模型较真实地反映了非冻结期作物生长过程中土壤中的水热状况以及地表和作物蒸散发的动态变化过程,可用于墒情预报以及农田蒸散发的研究. | Mao Xiaomin Yang Shixiu Lei Zhidong (Tsinghua University) | 1998 | 水利学报1998，29，7： | 21 |
| 5 | Identification of coastal wetlands of international importance for waterbirds:a review of China Coastal Waterbird Surveys 2005–2013显示文摘Background:China's coastal wetlands belong to some of the most threatened ecosystems worldwide.The loss and degradation of these wetlands seriously threaten waterbirds that depend on wetlands.Methods:The China Coastal Waterbird Census was organized by volunteer birdwatchers in China's coastal region.Waterbirds were surveyed synchronously once every month at 14 sites,as well as irregularly at a further 18 sites,between September 2005 and December 2013.Results:A total of 75 species of waterbirds met the 1 % population level Ramsar listing criterion at least once at one site.The number of birds of the following species accounted for over 20 % of the total flyway populations at a single site:Mute Swan(Cygnus olor),Siberia Crane(Grus leucogeranus),Far Eastern Oystercatcher(Haematopus osculans),Bar-tailed Godwit(Limosa lapponica),Spotted Greenshank(Tringa guttifer),Great Knot(Calidris tenuirostris),Spoon-billed Sandpiper(Calidris pygmeus),Saunders' s Gull(Larus saundersi),Relict Gull(Larus relictus),Great Cormorant(Phalacrocorax carbo),Eurasian Spoonbill(Platalea leucorodia),Black-faced Spoonbill(Platalea minor) and Dalmatian Pelican(Pelecanus crispus).A total of 26 sites supported at least one species of which their number met the1 % criterion.Forty-two species met the 1 % criterion in the Yellow River Delta,Shandong;29 at the Cangzhou coast,Hebei and 26 species at the Lianyungang coast,Jiangsu.Conclusions:The results highlight the international importance of China's coastal wetlands for waterbirds.This study also demonstrates that participation of local birdwatchers in waterbird surveys results in data that are invaluable not only for understanding the current status of waterbirds in China's coastal regions but also for waterbird conservation and management. | Qingquan Bai Jianzhong Chen Zhihong Chen Guotai Dong Jiangtian Dong Wenxiao Dong Vivian Wing Kan Fu Yongxiang Han Gang Lu Jing Li Yang Liu Zhi Lin Derong Meng Jonathan Martinez Guanghui Ni Kai Shan Renjie Sun Suixing Tian Fengqin Wang Zhiwei Xu Yat-tung Yu Jin Yang Zhidong Yang Lin Zhang Ming Zhang Xiangwu Zeng | 2015 | Chinese Birds2015，，3： | 20 |
| 6 | Sodium humate accelerates cutaneous wound healing by activating TGF-β/Smads signaling pathway in rats显示文摘Sodium humate(HA-Na) has been topically used as a wound healing and anti-inflammatory agent in folk medicine. In the present study, HA-Na was investigated for cutaneous wound healing in Sprague–Dawley rats. HA-Na solution(1.0%, w/v) was topically administered to rats undergoing excision wound models. Healing was assessed with a recombinant bovine basic fibroblast growth factor for external use as positive control. Wound healing rates were calculated on Day 3, 6, 9, 14 and 21 after injury, and tissues were also harvested after the same intervals for histological analysis. In addition, tissue hydroxyproline levels were measured. Furthermore, m RNA levels and protein expressions of transforming growth factor-β1, 2, 3(TGF-β1, 2, 3) were determined by RT-PCR and western blot. Protein expression levels of Smad-2,-3,-4 and-7 were also detected by western blot. Our study demonstrates that HA-Na has the capacity to promote wound healing in rats via accelerated wound contraction and increased hydroxyproline content. More importantly, these wound healing effects of HA-Na might be mediated through the TGF-β/Smad signaling pathway. HA-Na may be an effective agent for enhanced wound healing. | Yuanyuan Ji Aijun Zhang Xiaobin Chen Xiaoxia Che Kai Zhou Zhidong Wang | 2016 | Acta Pharmaceutica Sinica B2016，6，2： | 17 |
| 7 | Coinfection with influenza A virus enhances SARS-CoV-2 infectivity显示文摘The upcoming flu season in the Northern Hemisphere merging with the current COVID-19 pandemic raises a potentially severe threat to public health.Through experimental coinfection with influenza A virus(IAV)and either pseudotyped or live SARS-CoV-2 virus,we found that IAV preinfection significantly promoted the infectivity of SARS-CoV-2 in a broad range of cell types.Remarkably,in vivo,increased SARS-CoV-2 viral load and more severe lung damage were observed in mice coinfected with IAV.Moreover,such enhancement of SARS-CoV-2 infectivity was not observed with several other respiratory viruses,likely due to a unique feature of IAV to elevate ACE2 expression.This study illustrates that IAV has a unique ability to aggravate SARS-CoV-2 infection,and thus,prevention of IAV infection is of great significance during the COVID-19 pandemic. | Lei Bai Yongliang Zhao Jiazhen Dong Simeng Liang Ming Guo Xinjin Liu Xin Wang Zhixiang Huang Xiaoyi Sun Zhen Zhang Lianghui Dong Qianyun Liu Yucheng Zheng Danping Niu Min Xiang Kun Song Jiajie Ye Wenchao Zheng Zhidong Tang Mingliang Tang Yu Zhou Chao Shen Li Zhou Yu Chen Huan Yan Ke Lan Ke Xu | 2021 | Cell Research2021，31，4： | 16 |
| 8 | Necessity and feasibility of improving the residual resistance factor of polymer flooding in heavy oil reservoirs显示文摘The efficiency of water flooding in heavy oil reservoirs would be improved by increasing the viscosity of the displacing phase, but the sweep efficiency is not of significance due to the low mobility of the vicious oil. On the basis of mobility control theory, increasing the residual resistance factor not only reduces the water-oil mobility ratio but also decreases the requirement for viscosity enhancement of the polymer solution. The residual resistance factor caused by hydrophobic associating polymer solution is higher than that caused by polyacrylamide solution in brine containing high concentrations of calcium and magnesium ions. The results of numerical simulations show that the polymer flooding efficiency improved by increasing the residual resistance factor is far better than that by only increasing solution viscosity. The recovery factor of heavy oil reservoirs (70 mPa·s) can be enhanced by hydrophobic associating polymer solution of high residual resistance factor (more than 3) and high effective viscosity (24 mPa·s). Therefore, increasing the residual resistance factor of the polymer solution not only decreases the requirement for the viscosity of polymer solution injected into heavy oil reservoirs but also is favorable to enhanced oil recovery during polymer flooding. | Shi Leiting Ye Zhongbin Zhang Zhuo Zhou Changjiang Zhu Shanshan Guo Zhidong | 2010 | Petroleum Science2010，7，2： | 16 |
| 9 | The discovery of Neoproterozoic extensional structures and its significance for gas exploration in the Central Sichuan Block, Sichuan Basin, South China显示文摘The Central Sichuan Block(CSB) is the hardest block between the deep faults of Pujiang-Bazhong and Huaying Mountain in the central part of Sichuan Basin, which lies in the northwestern part of the upper Yangtze Craton. The CSB has long been considered as the oldest and most stable core area of Yangtze Craton, with the uniform basement and high level of hardening. Here we present a detailed interpretation of deep structures in the CSB by integrating high-resolution seismic data(approx. 50000 km2) with large-scale aeromagnetic data. Results show that eight Neoproterozoic extensional structures of different scales are nearly EW-, NEE-, and NW-trending in the CSB. Discovery of these extensional structures changes previous understanding of the CSB as a unified block. The extensional structures experienced one or two stages of extension in the longitudinal section, and filled with 3000–5000-m-thick weakly magnetic materials. Development of basal A-type granite in Weiyuan, Sichuan Basin and bimodal volcanic rocks of the Suxiong Formation, Western Sichuan confirms the CSB's Neoproterozoic extensional tectonic setting. The newly discovered Neoproterozoic extensional structures are of great significance for source rock and favorable sedimentary facies distribution, reservoir development, and gas accumulation. | GU ZhiDong WANG ZeCheng | 2014 | Science China Earth Sciences2014，57，11： | 16 |
| 10 | COVID-19: Challenges to GIS with Big Data显示文摘The outbreak of the 2019 novel coronavirus disease(COVID-19)has caused more than 100,000 people infected and thousands of deaths.Currently,the number of infections and deaths is still increasing rapidly.COVID-19 seriously threatens human health,production,life,social functioning and international relations.In the fight against COVID-19,Geographic Information Systems(GIS)and big data technologies have played an important role in many aspects,including the rapid aggregation of multi-source big data,rapid visualization of epidemic information,spatial tracking of confirmed cases,prediction of regional transmission,spatial segmentation of the epidemic risk and prevention level,balancing and management of the supply and demand of material resources,and socialemotional guidance and panic elimination,which provided solid spatial information support for decision-making,measures formulation,and effectiveness assessment of COVID-19 prevention and control.GIS has developed and matured relatively quickly and has a complete technological route for data preparation,platform construction,model construction,and map production.However,for the struggle against the widespread epidemic,the main challenge is finding strategies to adjust traditional technical methods and improve speed and accuracy of information provision for social management.At the data level,in the era of big data,data no longer come mainly from the government but are gathered from more diverse enterprises.As a result,the use of GIS faces difficulties in data acquisition and the integration of heterogeneous data,which requires governments,businesses,and academic institutions to jointly promote the formulation of relevant policies.At the technical level,spatial analysis methods for big data are in the ascendancy.Currently and for a long time in the future,the development of GIS should be strengthened to form a data-driven system for rapid knowledge acquisition,which signifies ts that GIS should be used to reinforce the social operation parameterization of models and methods,especially when providing support for social management. | Chenghu Zhou Fenzhen Su Tao Pei An Zhang Yunyan Du Bin Luo Zhidong Cao Juanle Wang Wen Yuan Yunqiang Zhu Ci Song Jie Chen Jun Xu Fujia Li Ting Ma Lili Jiang Fengqin Yan Jiawei Yi Yunfeng Hu Yilan Liao Han Xiao | 2020 | Geography and Sustainability2020，1，1： | 13 |
| 11 | An epidemiological analysis of the Beijing 2008 Hand-Foot-Mouth epidemic显示文摘This paper presents an empirical analysis of the epidemiological data concerning the 18445 HFMD-infected cases in Beijing in 2008.The main findings are as follows.(i) Seasonal variations in incidence were observed,with a peak observed during the summer season,especially in May.Male patients outnumber female patients by 1.57:1.(ii) Most cases occurred in children 4 years old or younger.Outperforming Weibull distribution and Gamma distribution as to model fitness when analyzing patient ages,log-normal distribution indicates that the estimated mean age is 3.4 years.(iii) The age distribution seems to indicate cyclic peaks with roughly one-year intervals.(iv) Correlation analyses (ρ=0.9864) show that time of birth in different months has an impact on the chance of being infected by HFMD.Birth month seems to present a high risk factor on infants and young children.(v) The morbidity rate is 132.7/100000 during the HFMD epidemic in Beijing in 2008.The morbidity map shows that the risks of HFMD infection in areas close to the city center and suburbans are much lower than those in the urban-rural transition zones.Spatial risks inferred from the morbidity map demonstrate a clear circular pattern.(vi) The prevention and control measures taken by the public health departments seem to be effective during the summer season,resulting in the early ending of the epidemic (one month earlier than the natural season) and reduced outbreak size. | CAO ZhiDong ZENG DaJun WANG QuanYi ZHENG XiaoLong WANG FeiYue | 2010 | Chinese Science Bulletin2010，55，12： | 12 |
| 12 | Piglets cloned from induced pluripotent stem cells显示文摘 | Nana Fan Jijun Chen Zhouchun Shang Hongwei Dou Guangzhen Ji Qingjian Zou Lu Wu Lixiazi He Fang Wang Kai Liu Na Liu Jianyong Han Qi Zhou Dengke Pan Dongshan Yang Bentian Zhao Zhen Ouyang Zhaoming Liu Yu Zhao Lin Lin Chongming Zhong Quanlei Wang Shouqi Wang Ying Xu Jing Luan Yu Liang Zhenzhen Yang Jing Li Chunxia Lu Gabor Vajta Ziyi Li Hongsheng Ouyang Huayan Wang Yong Wang Yang Yang Zhonghua Liu Hong Wei Zhidong Luan Miguel A Esteban Hongkui Deng Huanming Yang Duanqing Pei Ning Li Gang Pei Lin Liu Yutao Du Lei Xiao Liangxue Lai | 2013 | Cell Research2013，23，1： | 12 |
| 13 | A nano-cocrystal strategy to improve the dissolution rate and oral bioavailability of baicalein显示文摘Baicalein(BE) is one of the main active flavonoids representing the variety of pharmacological effects including anticancer, anti-inflammatory and cardiovascular protective activities, but it's very low solubility, dissolution rate and poor oral absorption limit the therapeutic applications. In this work, a nano-cocrystal strategy was successfully applied to improve the dissolution rate and bioavailability of BE. Baicalein-nicotinamide(BE-NCT) nanococrystals were prepared by high pressure homogenization and evaluated both in vitro and in vivo. Physical characterization results including scanning electron microscopy, dynamic light scattering, powder X-ray diffraction and differential scanning calorimetry demonstrated that BE-NCT nano-cocrystals were changed into amorphous state with mean particle size of 251.53 nm. In the dissolution test, the BE-NCT nano-cocrystals performed 2.17-fold and 2.54-fold enhancement than BE coarse powder in FaSSIF-V2 and FaSSGF. Upon oral administration, the integrated AUC0-t of BE-NCT nano-cocrystals(6.02-fold) was significantly higher than BE coarse powder(1-fold), BE-NCT cocrystals(2.87-fold) and BE nanocrystals(3.32-fold). Compared with BE coarse powder, BE-NCT cocrystals and BE nanocrystals, BENCT nano-cocrystals possessed excellent performance both in vitro and in vivo evaluations.Thus, it can be seen that nano-cocrystal is an appropriate novel strategy for improving dissolution rate and bioavailability of poor soluble natural products such as BE. | Jiaxin Pi Shuya Wang Wen Li Dereje Kebebe Ying Zhang Bing Zhang Dongli Qi Pan Guo Nan Li Zhidong Liu | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，2： | 12 |
| 14 | CUTTING REGULARITY AND DISCHARGE CHARACTERISTICS BY USING COMPOSITE COOLING LIQUID IN WIRE CUT ELECTRICAL DISCHARGE MACHINE WITH HIGH WIRE TRAVELING SPEED显示文摘The analysis of cutting regularity is provided through using and comparing two typical cooling liquids.It is proved that cutting regularity is greatly affected by cooling liquid's washing ability.Discharge characteristics and theoretic analysis between two electrodes are also discussed based on discharge waveform By using composite cooling liquid which has strong washing ability, the efficiency in the first stable cutting phase has reached more than 200 mm^2/min,and the roughness of the surface has reached R_a<0.8μm after the fourth cutting with more than 50 mm^2/min average cutting efficiency.It is pointed out that cutting situation of the wire cut electrical discharge machine with high wire traveling speed(HSWEDM)is better than the wire cut electrical discharge machine with low wire traveling speed(LSWEDM)in the condition of improving the cooling liquid washing ability.The machining indices of HSWEDM will be increased remarkably by using the composite cooling liquid. | LIU Zhidong | 2008 | Chinese Journal of Mechanical Engineering2008，21，5： | 11 |
| 15 | Absolute calibration of the Chang'E-1 IIM camera and its preliminary application显示文摘The interference imaging spectroradiometer (IIM) onboard the first lunar satellite of China 'Chang'E-1' can now provide approximately global high spectral and spatial resolution reflectance spectra of the Moon. It is the essential instrument with which to accomplish one of the four missions of the first lunar satellite of China. As the current data provided by the Lunar Exploration Program Center and National Astronomical Observatories (NAOC) are not reflectance and the sensor response is inhomogeneous in the line direction,users can not use the current data directly. Moreover,due to the narrow band range,IIM data cannot cover the absorption peak of the mafic minerals of the Moon completely,which limits its ability for identifying minerals. The main objective of this study is to describe the methods for absolute calibration,correction and acquiring the absorption center of minerals for IIM data. The results from our study show that in the space domain the sensor response decreases toward the left,and in the spectral domain the response of the longer bands is more inhomogeneous than that of the shorter bands. After the calibration and correction,the reflectance of IIM matches the earth-based telescopic spectra well,which suggests the possible use of the processed data in the geological research. A high correlation was found between the absorption center and the wavelength at which the first derivative equals 0,i.e.,the so-called Stagnation Point in the mathematical sense. In the end,we show a preliminary applied study of the two craters with diameter larger than 35 km using the calibrated data. The spectra of IIM data show that the lunar crust has compositional diversity within the km scale. Pure anorthosite may be found on the wall and floor of the Aristarchus crater with the map of absorption center,which indicates that anorthosite is ubiquitously present within the lunar crust. IIM,with its capacity to acquire lunar composition at the regional and global scale,will contribute to the research of lunar origin and evolution. | WU YunZhao XU XiSheng XIE ZhiDong TANG ZeSheng | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，12： | 11 |
| 16 | Adaptive inverse control of random vibration based on the filtered-X LMS algorithm显示文摘随机的颤动控制针对复制力量光谱在指定控制的密度(PSD ) 指。古典频率光谱均等算法需要计算多重频率反应函数(FRF ) 的一般水准,它变长在均等进程的控制循环时间。同样,反馈控制算法让很慢的集中由于反馈获得参数的小价值评价保证系统的稳定性。克服这些限制,随机的颤动的适应反的控制基于 filtered-X 最不吝啬平方(LMS ) 算法被建议。根据描述和频率领域的随机的颤动测试的重复特征,而且,频率领域 LMS 算法被采用精制 FRF 的反的特征而不是传统的时间领域 LMS 算法。这个反的特征,在控制下面被称为系统的阻抗函数,被用来直接更新驱动器 PSD。测试结果显示除了成功地避免发生在重复过程期间的不稳定性问题,适应控制策略最小化需要获得一个短控制环并且完成均等的时间的数量。关键词随机的颤动 - 力量光谱密度 - 频率反应功能 - 适应反的控制 - filtered-X LMS 算法旁边支持了:不在资助下面在大学里为新世纪优秀才能编程序。 | Yang Zhidong,Huang Qitao~(++),Han Junwei~§and Li Hongren~§National Key Laboratory of Robots Technique and System,Harbin Institute of Technology,Harbin 150080,China PhD Candidate ~++ PhD ~§Professor | 2010 | Earthquake Engineering and Engineering Vibration2010，9，1： | 10 |
| 17 | Preparation,characterization of Mo,Ag-loaded BiVO_4 and comparison of their degradation of methylene blue显示文摘Two types of metal-loaded visible-light-driven photocatalysts,Mo-BiVO4and Ag-BiVO4,were synthesized by wet impregnation method.Material poperties were characterized by UV-vis diffuse reflectance spectroscopy,X-ray diffraction,field emission scanning electron microscopy,X-ray photoelectron spectroscopy and low temperature nitrogen adsorption-desorption.Photocatalytic activity of the obtained materials was investigated through degrading methylene blue(MB) solution under visible-light irradiation.The results reveal that both metal loaded-BiVO4catalysts have monoclinic scheelite structure.Mo and Ag exist as oxides on the surface of the particles.The changes of absorption in visible-light region,band gap(E g) and specific surface area(A BET) caused by loading Ag are more obvious than those caused by loading Mo.But the isoelectric point of Ag-BiVO4decreases less than that of Mo-BiVO4does.Both catalysts show higher photocatalytic activity than pure BiVO4,resulting in the significantly improved efficiency of degradation of MB.And the degradation efficiency of these two metal-loaded BiVO4photocatalysts is similar to each other.However,mechanisms of such enhancement are different.The decrease of isoelectric point helps Mo-BiVO4improve the degradation efficiency.As for Ag-BiVO4,the augmentation of absorption in visible-light region as well as the abatement of E g plays more important roles. | LIU KunJie CHANG ZhiDong LI WenJun CHE Ping ZHOU HuaLei | 2012 | Science China Chemistry2012，55，9： | 10 |
| 18 | Effect of alkalis on deacetylation of konjac glucomannan in mechano-chemical treatment显示文摘This paper presents experimental results on the effect of alkalis such as NaOH,KOH and Ca(OH) 2 on deacetylation of a konjac glucomannan(KGM) powder under mechano-chemical(MC) treatment. The results show that the alkalinity of modiers is a dominant factor for deacetylation of KGM. In addition,characteristics,such as swelling property,viscous stability and thermal behavior of the deacetylated KGM are analyzed. | Zhidong Pan Junjie Meng Yanmin Wang | 2011 | Particuology2011，9，3： | 10 |
| 19 | A two-step weighted least-squares method for joint estimation of source and sensor locations: A general framework显示文摘It is well known that the Two-step Weighted Least-Squares(TWLS) is a widely used method for source localization and sensor position refinement. For this reason, we propose a unified framework of the TWLS method for joint estimation of multiple disjoint sources and sensor locations in this paper. Unlike some existing works, the presented method is based on more general measurement model, and therefore it can be applied to many different localization scenarios.Besides, it does not have the initialization and local convergence problem. The closed-form expression for the covariance matrix of the proposed TWLS estimator is also derived by exploiting the first-order perturbation analysis. Moreover, the estimation accuracy of the TWLS method is shown analytically to achieve the Cramér-Rao Bound(CRB) before the threshold effect takes place. The theoretical analysis is also performed in a common mathematical framework, rather than aiming at some specific signal metrics. Finally, two numerical experiments are performed to support the theoretical development in this paper. | Ding WANG Jiexin YIN Tao TANG Ruirui LIU Zhidong WU | 2019 | Chinese Journal of Aeronautics2019，32，2： | 8 |
| 20 | Gene expression profiles of ERCC1, TYMS, RRM1, TUBB3 and EGFR in tumor tissue from non-small cell lung cancer patients显示文摘 | Yu Daping Li Jie Han Yi Liu Shuku Xiao Ning Li Yunsong Sun Xiaojun Liu Zhidong | 2014 | Chinese Medical Journal2014，，8： | 7 |
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