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| 1 | The Tea Tree Genome Provides Insights into Tea Flavor and Independent Evolution of Caffeine Biosynthesis显示文摘茶是世界有巨大的经济、药用、文化的重要性的最旧、很流行的包含咖啡因的饮料。这里,我们在场第一个高质量的核苷酸序列充满重复(80.9%) ,栽培的茶树山茶 sinensis 的 3.02-Gb 染色体。我们证明茶树的一种非常地大的染色体尺寸从一些 LTR retrotransposon 家庭的慢、稳定、长期的扩大被结果。除了一个最近的整个染色体的复制事件,基因的系特定的扩大把新陈代谢的生合成与 flavonoid 联系了被发现,它提高 catechin 生产,萜烯酶激活,和应力公差,为茶风味和改编的重要特征。我们相对可可子和咖啡表明一个独立人士和茶咖啡因合成小径的快速的进化。在 25 山茶种类之中的比较研究表明那更高的表情大多数 flavonoid- 和咖啡因铺平 -- 然而并非 theanine 相关的基因贡献 catechins 和咖啡因的增加的生产并且因此提高处理茶的适用性和茶质量。这些新奇调查结果为进一步的 metabolomic 和典型生合成小径的功能的 genomic 精炼铺平道路并且将帮助开发将最后满足并且吸引世界范围的更多的茶喝酒者的茶风味的一个更多样化的集合。 | En-Hua Xia Hai-Bin Zhang Jun Sheng Kui Li Qun-Jie Zhang Changhoon Kim Yun Zhang Yuan Liu Ting Zhu Wei Li Hui Huang Yan Tong Hong Nan Cong Shi Chao Shi Jian-Jun Jiang Shu-Yan Mao Jun-Ying Jiao Dan Zhang Yuan Zhao You-Jie Zhao Li-Ping Zhang Yun-Long Liu Ben-Ying Liu Yue Yu Sheng-Fu Shao De-Jiang Ni Evan E. Eichler Li-Zhi Gao | 2017 | Molecular Plant2017，10，6： | 113 |
| 2 | The Chromosome-Based Rubber Tree Genome Provides New Insights into Spurge Genome Evolution and Rubber Biosynthesis显示文摘The rubber tree,Hevea brasiliensis,produces natural rubber that serves as an essential industrial raw material.Here,we present a high-quality reference genome for a rubber tree cultivar GT1 using single-molecule real-time sequencing(SMRT)and Hi-C technologies to anchor the~1.47-Gb genome assembly into 18 pseudochromosomes.The chromosome-based genome analysis enabled us to establish a model of spurge chromosome evolution,since the common paleopolyploid event occurred before the split of Hevea and Manihot.We show recent and rapid bursts of the three Hevea-specific LTR-retrotransposon families during the last 10 million years,leading to the massive expansion by~65.88%(~970 Mbp)of the whole rubber tree genome since the divergence from Manihot.We identify large-scale expansion of genes associated with whole rubber biosynthesis processes,such as basal metabolic processes,ethylene biosynthesis,and the activation of polysaccharide and glycoprotein lectin,which are important properties for latex production.A map of genomic variation between the cultivated and wild rubber trees was obtained,which contains~15.7 million high-quality single-nucleotide polymorphisms.We identified hundreds of candidate domestication genes with drastically lowered genomic diversity in the cultivated but not wild rubber trees despite a relatively short domestication history of rubber tree,some of which are involved in rubber biosynthesis.This genome assembly represents key resources for future rubber tree research and breeding,providing novel targets for improving plant biotic and abiotic tolerance and rubber production. | Jin Liu Cong Shi Cheng-Cheng Shi Wei Li Qun-Jie Zhang Yun Zhang Kui Li Hui-Fang Lu Chao Shi Si-Tao Zhu Zai-Yun Xiao Hong Nan Yao Yue Xun-Ge Zhu Yu Wu Xiao-Ning Hong Guang-Yi Fan Yan Tong Dan Zhang Chang-Li Mao Yun-Long Liu Shi-Jie Hao Wei-Qing Liu Mei-Qi Lv Hai-Bin Zhang Yuan Liu Ge-Ran Hu-tang Jin-Peng Wang Jia-Hao Wang Ying-Huai Sun Shu-Bang Ni Wen-Bin Chen Xing-Cai Zhang Yuan-Nian Jiao Evan E.Eichler Guo-Hua Li Xin Liu Li-Zhi Gao | 2020 | Molecular Plant2020，13，2： | 15 |
| 3 | An important role of the hepcidin-ferroportin signaling in affecting tumor growth and metastasis显示文摘 | Wenli Guo Shuping Zhang Yue Chen Daoqiang Zhang Lin Yuan Haibo Cong Sijin Liu | 2015 | Acta Biochimica et Biophysica Sinica2015，47，9： | 14 |
| 4 | Liquid-liquid phase separation in biology: mechanisms,physiological functions and human diseases显示文摘Cells are compartmentalized by numerous membrane-enclosed organelles and membraneless compartments to ensure that a wide variety of cellular activities occur in a spatially and temporally controlled manner. The molecular mechanisms underlying the dynamics of membrane-bound organelles, such as their fusion and fission, vesicle-mediated trafficking and membrane contactmediated inter-organelle interactions, have been extensively characterized. However, the molecular details of the assembly and functions of membraneless compartments remain elusive. Mounting evidence has emerged recently that a large number of membraneless compartments, collectively called biomacromolecular condensates, are assembled via liquid-liquid phase separation(LLPS). Phase-separated condensates participate in various biological activities, including higher-order chromatin organization,gene expression, triage of misfolded or unwanted proteins for autophagic degradation, assembly of signaling clusters and actin-and microtubule-based cytoskeletal networks, asymmetric segregations of cell fate determinants and formation of pre-and post-synaptic density signaling assemblies. Biomacromolecular condensates can transition into different material states such as gel-like structures and solid aggregates. The material properties of condensates are crucial for fulfilment of their distinct functions, such as biochemical reaction centers, signaling hubs and supporting architectures. Cells have evolved multiple mechanisms to ensure that biomacromolecular condensates are assembled and disassembled in a tightly controlled manner. Aberrant phase separation and transition are causatively associated with a variety of human diseases such as neurodegenerative diseases and cancers. This review summarizes recent major progress in elucidating the roles of LLPS in various biological pathways and diseases. | Hong Zhang Xiong Ji Pilong Li Cong Liu Jizhong Lou Zheng Wang Wenyu Wen Yue Xiao Mingjie Zhang Xueliang Zhu | 2020 | Science China(Life Sciences)2020，63，7： | 11 |
| 5 | Microwave ablation of primary breast cancer inhibits metastatic progression in model mice via activation of natural killer cells显示文摘Surgery is essential for controlling the symptoms and complications of stage IV breast cancer.However,locoregional treatment of primary tumors often results in distant progression,including lung metastasis,the most common type of visceral metastasis.As a minimally invasive thermal therapy,microwave ablation(MWA)has been attempted in the treatment of breast cancer,but the innate immune response after MWA has not yet been reported.Using two murine models of stage IV breast cancer,we found that MWA of primary breast cancer inhibited the progression of lung metastasis and improved survival.NK cells were activated after MWA of the primary tumor and exhibited enhanced cytotoxic functions,and the cytotoxic pathways of NK cells were activated.Depletion experiments showed that NK cells but not CD4+or CD8+T cells played a pivotal role in prolonging survival.Then,we found that compared with surgery or control treatment,MWA of the primary tumor induced completely different NK-cell-related cytokine profiles.Macrophages were activated after MWA of the primary tumor and produced IL-15 that activated NK cells to inhibit the progression of metastasis.In addition,MWA of human breast cancer stimulated an autologous NK-cell response.These results demonstrate that MWA of the primary tumor in metastatic breast cancer inhibits metastatic progression via the macrophage/IL-15/NK-cell axis.MWA of the primary tumor may be a promising treatment strategy for de novo stage IV breast cancer,although further substantiation is essential for clinical testing. | Muxin Yu Hong Pan Nan Che Li Li Cong Wang Yue Wang Ge Ma Mengjia Qian Jiawei Liu Mingjie Zheng Hui Xie Lijun Ling Yi Zhao Xiaoxiang Guan Qiang Ding Wenbin Zhou Shui Wang | 2021 | Cellular & Molecular Immunology2021，18，9： | 5 |
| 6 | DBU-based CO2 absorption-mineralization system: Reaction process,feasibility and process intensification显示文摘Amine-based carbon dioxide(CO2)capture is still limited by high desorption energy consumption.Fixing CO2 into carbonate is a safer and more permanent method.In this work,calcium oxide(CaO)is introduced to perform chemical desorption instead of thermal desorption on 1,8-diazabicyclo[5.4.0]undec-7-ene(DBU)aqueous solution after CO2 absorption.The X-ray diffraction(XRD)patterns of solid products show the formation of calcite calcium carbonate(CaCO3),which prove the feasibility of this method.The effects of reaction temperature,reaction time and Ca2+/CO32-molar ratios on the related reactions in CO2 absorption-mineralization process and CaCO3 precipitation are discussed,and purer CaCO3 is obtained by ultrasonic treatment.The CaCO3 content can be increased to 95.8%and the CO2 desorption ratio can achieve 80%by 30 min ultrasonic dispersion treatment under the conditions(40℃,180 min,Ca2+/CO32-molar ratio=1.0).After five cycles,DBU aqueous solution shows stable CO2 absorption and mineralization ability.Fourier transform infrared spectroscopy(FT-IR)spectra of the reaction process also indicate the regeneration of the solvent.Compared with thermal desorption,this process is exothermic,almost without no additional heat. | Cong Luo Kejing Wu Hairong Yue Yingying Liu Yingming Zhu Wei Jiang Houfang Lu Bin Liang | 2020 | Chinese Journal of Chemical Engineering2020，28，4： | 4 |
| 7 | Identification of in vitro and in vivo metabolites of 12β-hydroxylveratroylzygadenine associated with neurotoxicity by using HPLC–MS/MS显示文摘Metabolism study was carried out on 12b-hydroxylveratroylzygadenine(VOG) that is a cevine-type alkaloid existing in Veratrum nigrum L. and a neurotoxic component. In order to better understand the potential mechanism of neurotoxicity of VOG, this study measured VOG-induced DNA damage in the cerebellum and cerebral cortex of mice after 7 days repetitive oral dose by using single-cell gel electrophoresis(Comet assay). High performance liquid chromatography-tandem mass spectrometry(LC–MS/MS) was developed and applied to separate and identify in vitro and in vivo metabolites of VOG for investing the possible relationship of metabolism and neurotoxicity. In vitro experiment was carried out using rat liver microsomes, while the in vivo study was conducted on rats. The obtained results indicated that VOG might cause DNA damage in cerebellum and cerebral cortex of mice in a dosedependent manner. Hydrolysis of ester bond and O-demethylation were proposed to be the main in vivo metabolic pathways of VOG, while the major in vitro metabolic pathways were proposed as methyl oxidation to aldehyde, dehydrogenation, hydrolysis of ester bond, hydrolysis of ester bond together with acetylation, and methoxylation. O-Demethylation reaction was likely to be associated with reactive oxygen species production, leading to the DNA damage. | Yue Cong Jing-Gong Guo Zhi Tang Qing-Chun Zhang Zong-Wei Cai | 2014 | Chinese Chemical Letters2014，25，8： | 3 |
| 8 | Orbital-angular-momentum-based reconfigurable optical switching and routing显示文摘Orbital angular momentum(OAM) has gained interest due to its potential to increase capacity in optical communication systems as well as an additional domain for reconfigurable networks. This is due to the following:(i) coaxially propagated OAM beams with different charges are mutually orthogonal,(ii) OAM beams can be efficiently multiplexed and demultiplexed, and(iii) OAM charges can be efficiently manipulated. Therefore, multiple data-carrying OAM beams could have the potential capability for reconfigurable optical switching and routing. In this paper, we discuss work involving reconfigurable OAM-based optical add/drop multiplexing, space switching,polarization switching, channel hopping, and multicasting. | Alan E.Willner Long Li Guodong Xie Yongxiong Ren Hao Huang Yang Yue Nisar Ahmed Moshe J.Willner Asher J.Willner Yan Yan Zhe Zhao Zhe Wang Cong Liu Moshe Tur Solyman Ashrafi | 2016 | Photonics Research2016，4，5： | 2 |
| 9 | Synthesis and characterization of conjugated polymer containing azobenzene and oxadiazole units显示文摘包含偶氮苯和 oxadiazole 单位的新奇结合的聚合物通过多步合成被综合。单体和聚合物的结构和性质与红外被描绘并且评估, 1 H NMR,紫外, TGA 和 GPC 分别地。有 alkoxy 的长方面链的聚合物显示出好溶解度,热稳定性和相片异构化性质。 | Yue Zhang Shi Jun Yu Lu Wang Cong Li | 2009 | Chinese Chemical Letters2009，20，2： | 2 |
| 10 | Visible-light stimulated synaptic plasticity in amorphous indium−gallium−zinc oxide enabled by monocrystalline double perovskite for high-performance neuromorphic applications显示文摘Photoelectric synaptic devices have been considered as one of the key components in artificial neuromorphic systems due to their excellent capability to emulate the functions of visual neurons,such as light perception and image processing.Herein,we demonstrate an optically-stimulated artificial synapse with a clear photoresponse from ultraviolet to visible light,which is established on a novel heterostructure consisting of monocrystalline Cs2AgBiBr6 perovskite and indium–gallium–zinc oxide(IGZO)thin film.As compared with pure IGZO,the heterostructure significantly enhances the photoresponse and corresponding synaptic plasticity of the devices,which originate from the superior visible absorption of single-crystal Cs2AgBiBr6 and effective interfacial charge transfer from Cs2AgBiBr6 to IGZO.A variety of synaptic behaviors are realized on the fabricated thin-film transistors,including excitatory postsynaptic current,paired pulse facilitation,short-term,and long-term plasticity.Furthermore,an artificial neural network is simulated based on the photonic potentiation and electrical depression effects of synaptic devices,and an accuracy rate up to 83.8%±1.2%for pattern recognition is achieved.This finding promises a simple and efficient way to construct photoelectric synaptic devices with tunable spectrum for future neuromorphic applications. | Fu Huang Feier Fang Yue Zheng Qi You Henan Li Shaofan Fang Xiangna Cong Ke Jiang Ye Wang Cheng Han Wei Chen Yumeng Shi | 2023 | Nano Research2023，16，1： | 2 |
| 11 | Porcine Parvovirus Inducing Autophagy to Benefit Its Replication显示文摘Porcine parvovirus(PPV) is one of the major causes of reproductive failure in pigs, which poses a great threat to the pig breeding industry and results in tremendous economic losses worldwide. Autophagy is the biological process of cell self-defense and self-protection. Despite many viruses can cause cell autophagy, when they enter cell or copied, the relationship between autophagy and PPV infection has not been reported. In this study, impact of autophagy after swine testicular(ST) cells infected by PPV was studied. Autophagy was demonstrated by the effective replication of PPV through transmission electron microscopy, immunofluorescence and western blot analysis. Moreover, autophagy was confirmed to benefit PPV replication by real-time fluorescence quantitative PCR and determination of median tissue culture infective dose(TCID_(50)). For the first time, the complex interaction between PPV infection and autophagy was explored in this study. It indicated that PPV could induce autophagy in ST cells, which in turn facilitated its own replication, which might be one of the mechanisms of the virus infection. These findings could facilitate the study of the pathogenesis of PPV infection and provide new insight into the development of effective therapeutic strategies. | Zhang Yue Li Xiao-xue Zhong Ming Chen Hui-jie Huang Xiao-dan Bai Yun-yun Cong Ying-ying Zhang Rui-li Li Guang-xing | 2018 | Journal of Northeast Agricultural University(English Edition)2018，25，4： | 2 |
| 12 | Inverted U-Shaped Associations between Glycemic Indices and Serum Uric Acid Levels in the General Chinese Population:Findings from the China Cardiometabolic Disease and Cancer Cohort(4C)Study显示文摘Objective The relationship between serum uric acid(SUA)levels and glycemic indices,including plasma glucose(FPG),2-hour postload glucose(2 h-PG),and glycated hemoglobin(HbA1 c),remains inconclusive.We aimed to explore the associations between glycemic indices and SUA levels in the general Chinese population.Methods The current study was a cross-sectional analysis using the first follow-up survey data from The China Cardiometabolic Disease and Cancer Cohort Study.A total of 105,922 community-dwelling adults aged≥40 years underwent the oral glucose tolerance test and uric acid assessment.The nonlinear relationships between glycemic indices and SUA levels were explored using generalized additive models.Results A total of 30,941 men and 62,361 women were eligible for the current analysis.Generalized additive models verified the inverted U-shaped association between glycemic indices and SUA levels,but with different inflection points in men and women.The thresholds for FPG,2 h-PG,and HbA1 c for men and women were 6.5/8.0 mmol/L,11.0/14.0 mmol/L,and 6.1/6.5,respectively(SUA levels increased with increasing glycemic indices before the inflection points and then eventually decreased with further increases in the glycemic indices).Conclusion An inverted U-shaped association was observed between major glycemic indices and uric acid levels in both sexes,while the inflection points were reached earlier in men than in women. | ZHU Yuan Yue ZHENG Rui Zhi WANG Gui Xia CHEN Li SHI Li Xin SU Qing XU Min XU Yu CHEN Yu Hong YU Xue Feng YAN Li WANG Tian Ge ZHAO Zhi Yun QIN Gui Jun WAN Qin CHEN Gang GAO Zheng Nan SHEN Fei Xia LUO Zuo Jie QIN Ying Fen HUO Ya Nan LI Qiang YE Zhen ZHANG Yin Fei LIU Chao WANG You Min WU Sheng Li YANG Tao DENG Hua Cong ZHAO Jia Jun CHEN Lu Lu MU Yi Ming TANG Xu Lei HU Ru Ying WANG Wei Qing NING Guang LI Mian LU Jie Li BI Yu Fang | 2021 | Biomedical and Environmental Sciences2021，34，1： | 2 |
| 13 | Progress, challenge and significance of building a carbon industry system in the context of carbon neutrality strategy显示文摘Carbon dioxide storage and utilization has become an inevitable trend and choice for sustainable development under the background of global climate change and carbon neutrality.Carbon industry which is dominated by CO_(2) capture,utilization and storage/CO_(2) capture and storage(CCUS/CCS)is becoming a new strategic industry under the goal of carbon neutrality.The sustainable development of carbon industry needs to learn from the experiences of global oil and gas industry development.There are three types of“carbon”in the earth system.Black carbon is the CO_(2) that has not been sequestered or used and remains in the atmosphere for a long time;grey carbon is the CO_(2) that has been fixed or permanently sequestered in the geological body,and blue carbon is the CO_(2) that could be converted into products for human use through biological,physical,chemical and other ways.The carbon industry system covers carbon generation,carbon capture,carbon transportation,carbon utilization,carbon sequestration,carbon products,carbon finance,and other businesses.It is a revolutionary industrial field to completely eliminate“black carbon”.The development of carbon industry technical system takes carbon emission reduction,zero carbon,negative carbon and carbon economy as the connotation,and the construction of a low-cost and energy-efficient carbon industry system based on CCUS/CCS are strategic measures to achieve the goal of carbon neutrality and clean energy utilization globally.This will promote the“four 80%s”transformation of China's energy supply,namely,to 2060,the percentage of zero-carbon new energy in the energy consumption will be over 80%and the CO_(2) emission will be decreased by 80%to ensure the carbon emission reduction of total 80×10^(8) t from the percentage of carbon-based fossil energy in the energy consumption of over 80%,and the percentage of CO_(2) emission from energy of over 80%in 2021.The carbon industry in China is facing three challenges,large CO_(2) emissions,high percentage of coal in energy consumption,and poor innovative system.Three strategic measures are proposed accordingly,including:(1)unswervingly develop carbon industrial system and ensure the achievement of carbon neutrality as scheduled by 2060;(2)vigorously develop new energy sources and promote a revolutionary transformation of China’s energy production and consumption structure;(3)accelerate the establishment of scientific and technological innovation system of the whole CO_(2) industry.It is of great significance for continuously optimization of ecological environment and construction of green earth and ecological earth to develop the carbon industry system,utilize clean energy,and achieve the strategic goal of global carbon neutrality. | ZOU Caineng WU Songtao YANG Zhi PAN Songqi WANG Guofeng JIANG Xiaohua GUAN Modi YU Cong YU Zhichao SHEN Yue | 2023 | Petroleum Exploration and Development2023，50，1： | 1 |
| 14 | The draftgenome of a diploid cotton gossypium raimondii 显示文摘 | Kunbo Wang Zhiwen Wang Fuguang Li Wuwei Ye Junyi Wang Guoli Song Zhen Yue Lin Cong Haihong Shang Shilin Zhu Changsong Zou Qin Li Youlu Yuan Cairui Lu Hengling Wei Caiyun Gou Zequn Zheng Ye Yin Xueyan Zhang Kun Liu Bo Wang Chi Song Nan Shi Russell J Kohel Richard G Percy John Z Yu Yu-xian Zhu Jun Wang Shuxun Yu | 2012 | Nat Genet2012，，44： | 1 |
| 15 | Event-Related Potentials Measurement of Perception to 3D Motion in Depth显示文摘An approach to the direct measure of stereoscopic(3D) videos with different accelerations was presented,using electroencephalography(EEG).In the study,subjects viewed 1-sec-long video clips with a stone approaching straightforward and were required to perceive whether they were able to catch the outline of stone.Peak amplitude of each part was extracted from P03 electrode located at the occipital region corresponding visual processing and cognition.Three components were conspicuously observed in the periods:650-800 ms,800-900 ms and 1150-1250 ms,which were called N310,N480 and N810 in this paper.N310 related to the perception to the initial stage of movement.Movement indepth could be immediately perceived when initial speed was not less than 3 m/s.N480 related to the perception to acceleration/deceleration.N810 related to the perception to the point a movement was about to vanish.Subjects couldn't perceive the outline with the final speed more than 3 m/s.For 3 m/s,subjects were in a dilemma to judge with the detecting rate 54%.Together,component analysis combined with behavioral results,it was supposed that 3 m/s to be the threshold to completely perceive the outline. | SHEN Lili DU Weirong WANG Cong YUE Guanghui | 2015 | China Communications2015，12，5： | 1 |
| 16 | Investigating of fracture features of steel plates with ceramic coating at dynamic three-point bending显示文摘 | Chen Ke Xu Yue Cong Meihua | 2002 | Physical Mesomechanics2002，5，4： | 1 |
| 17 | An efficient approach to representing and mining knowledge from Qing court medical records显示文摘在 Qing 法庭上研究医药记录(RQCMR ) 是被第六合作者 Keji,陈和他的同事编辑并且注解的一本大卷的书,并且由帝国家庭的所有医药记录和 Qing 王朝的贵族组成。为了揭示并且利用他们的高度,在繁体中文药研究和现代临床的实践珍视两个,我们开发了转变 Qing 场的一个方法医药记录(QCMR ) 进一个机器可读的、结构化的代表,以便统计分析和数据采矿能精确地被执行。方法由框架本体论组成基于的医药语言,叫了 MedL 代表 QCMR,为编 MedL 框架进一个数据库的一个分析器,和一个探险模式采矿技术。与这个方法,全部 RQCMR 体积被转变成一个数据库,医药模式可以是从数据库的 mined。 | Weimin WANG Jingchun ZHANG Cong CAO Tao HOU Yue LIU Keji CHEN | 2011 | Frontiers of Computer Science2011，5，4： | 1 |
| 18 | The eurichment and identification of methyl alkanones from thermally soluble Sheng!i !ignite显示文摘 | ZHOUJ ZONG Z M CHEN B YANG Z S LI P LU Y YUE XM CONG X S WEI Y B WANG Y G FAN X ZHAO Y P WEI X Y | 2013 | Energy Sources Part A2013，35，23： | 1 |
| 19 | Selenium-enriched Cardamine violifolia protects against sepsis-induced intestinal injury by regulating mitochondrial fusion in weaned pigs显示文摘Sepsis is a life-threatening organ dysfunction caused by the dysregulated response of the host to an infection, and treatments are limited. Recently, a novel selenium source, selenium-enriched Cardamine violifolia(SEC) has attracted much attention due to its anti-inflammatory and antioxidant properties, but little is known about its role in the treatment of sepsis. Here, we found that SEC alleviated LPS-induced intestinal damage, as indicated by improved intestinal morphology, and increased disaccharidase activity and tight junction protein expression. Moreover, SEC ameliorated the LPS-induced release of pro-inflammatory cytokines, as indicated by decreased IL-6 level in the plasma and jejunum. Moreover, SEC improved intestinal antioxidant functions by regulating oxidative stress indicators and selenoproteins. In vitro, TNF-α-challenged IPEC-1 cells were examined and showed that selenium-enriched peptides, which are the main functional components extracted from Cardamine violifolia(CSP), increased cell viability, decreased lactate dehydrogenase activity and improved cell barrier function. Mechanistically, SEC ameliorated LPS/TNF-α-induced perturbations in mitochondrial dynamics in the jejunum and IPEC-1 cells. Moreover, CSPmediated cell barrier function is primarily dependent on the mitochondrial fusion protein MFN2 but not MFN1. Taken together,these results indicate that SEC mitigates sepsis-induced intestinal injury, which is associated with modulating mitochondrial fusion. | Dan Wang Yanling Kuang Qingqing Lv Wenshuai Xie Xiao Xu Huiling Zhu Yue Zhang Xin Cong Shuiyuan Cheng Yulan Liu | 2023 | Science China(Life Sciences)2023，66，9： | 1 |
| 20 | Distance sets with diameter graph being cycle显示文摘 | WEI Xianglin LI Guogang CONG Yue | 2014 | Taiwanese Journal of Mathematics2014，18，6： | 1 |
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