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| 1 | Nonlinear quantum interferometry with Bose condensed atoms显示文摘在量 interferometry,为高精确的大小的成就控制并且利用非线性的相互作用是重要的。由于他们的长连贯时间和高可控制性,包括 Bose 的 ultracold 原子压缩了原子广泛地为量 interferometry 被使用了。这里,我们与 Bose 在量 interferometry 的理论研究考察最近的进步压缩原子。特别地,我们集中于原子原子相互作用导致的非线性的现象,并且怎么控制并且利用这些非线性的现象。与吝啬地的描述,由于原子原子相互作用,事波浪 solitons 出现在干扰模式,和宏观的量自我套住在 Bose-Josephson 连接存在。与许多身体描述,原子原子相互作用能产生非古典的纠纷,它能被利用在标准量限制以外完成高精确的大小。 | Chaohong Lee (1) Jiahao Huang (1) Haiming Deng (1) Hui Dai (1) Jun Xu (1) | 2012 | Frontiers of physics2012，7，1： | 6 |
| 2 | A multi-institutional retrospective study of hyperthermic plus intravesical chemotherapy versus intravesical chemotherapy treatment alone in intermediate and high risk nonmuscle-invasive bladder cancer显示文摘Objective:To compare the efficacy and safety of hyperthermic intravesical chemotherapy(HIVEC)and intravesical chemotherapy(IVEC)in patients with intermediate and high risk nonmuscle-invasive bladder cancer(NMIBC)after transurethral resection.Methods:We included 560 patients diagnosed with primary or recurrent NMIBC between April 2009 and December 2015 at 1 of 6 tertiary centers.We matched 364 intermediate or high risk cases and divided them into 2 groups:the HIVEC+IVEC group[chemohyperthermia(CHT)composed of 3 consecutive sessions followed by intravesical instillation without hyperthermia]and the IVEC group(intravesical instillation without hyperthermia).The data were recorded in the database.The primary endpoint was 2-year recurrence-free survival(RFS)in all NMIBC patients(n=364),whereas the secondary endpoints were the assessment of radical cystectomy(RC)and 5-year overall survival(OS).Results:There was a significant difference in the 2-year RFS between the two groups in all patients(n=364;HIVEC+IVEC:82.42%vs.IVEC:74.18%,P=0.038).Compared with the IVEC group,the HIVEC+IVEC group had a lower incidence of RC(P=0.0274).However,the 5-year OS was the same between the 2 groups(P=0.1434).Adverse events(AEs)occurred in 32.7%of all patients,but none of the events was serious(grades 3–4).No difference in the incidence or severity of AEs between each treatment modality was observed.Conclusions:This retrospective study showed that HIVEC+IVEC had a higher 2-year RFS and a lower incidence of RC than IVEC therapy in intermediate and high risk NMIBC patients.Both treatments were well-tolerated in a similar manner. | Qiang Ruan Degang Ding Bin Wang Chaohong He Xuequn Ren Zhenhua Feng Zhigang Pang Jin Wang Xiangliang Zhang Hongsheng Tang Jiahong Wang Qingjun He Ziying Lei Quanxing Liao Jiali Luo Shuzhong Cui | 2021 | Cancer Biology & Medicine2021，18，1： | 4 |
| 3 | Analysis of Aroma Volatile Compounds in Fuji Apple Using SPME with Different Fiber Coatings显示文摘The aroma volatile compounds in Fuji apple were isolated by solid-phase microextraction( SPME),and detected by gas chromatography-mass spectrometry( GC-MS). The results showed that the optimal retention time of the heating up of capillary columns was 5 min. Of the seven fibers used in this work,DVB/CAR/PDMS was found to be the most suitable to extract the aroma volatile compounds in Fuji apple. A total number of 43 volatile compounds were identified according to their retention time on capillary columns and their mass spectra,including eleven esters,ten alcohols,ten aldehydes,seven alkenes,two anhydrides,one ketone,one phenol and one ether. This detection method will provide a new foundation for analysis of volatile compounds in apple were identified. | Jie LI Jicheng HAN Haie ZHANG Chaohong ZHANG Minmin LI Yu WANG | 2020 | Agricultural Biotechnology2020，9，3： | 4 |
| 4 | Interaction of Caffeine with Bovine Serum Albumin: Determination of Binding Constants and the Binding Site by Spectroscopic Methods显示文摘 | Wu, Qiong Jiang, Fenglei Li, Chaohong Hu, Yanjun Liu, Yi | 2011 | Chinese Journal of Chemistry2011，29，3： | 3 |
| 5 | T cells expressing CD5/CD7 bispecific chimeric antigen receptors with fully human heavy-chain-only domains mitigate tumor antigen escape显示文摘Bispecific chimeric antigen receptor T-cell(CAR-T)therapies have shown promising results in clinical trials for advanced B-cell malignancies.However,it is challenging to broaden the success of bispecific CAR-T therapies to treat refractory/relapse(r/r)T-cell leukemia/lymphoma because targeting multiple T-cell-expressing antigens leads to exacerbated CAR-T cell fratricide and potential safety concerns.Fully human heavy chain variable(FHVH)antibodies that specifically target CD5 or CD7 were screened and constructed to CD5/CD7 bispecific CARs.A truncated Epidermal growth factor receptor were integrated into CAR constructs to address safety concerns.To tackle the fratricidal issue of CAR-T cells targeting T-cell-pan marker(s),CRISPR/Cas9-based CD5 and CD7 genes knockout were performed before lentiviral transduction of bispecific CARs.Functional comparison between different bispecific CAR structures:tandem CARs and dual CAR were performed in vitro and in vivo to determine the optimal construct suitable for addressing T-cell malignancy antigen escape in clinical setting.Knockout of CD5 and CD7 prevents fratricide of CD5/CD7 bispecific CAR-T cells,and FHVH-derived CD5/CD7 bispecific CAR-T cells demonstrate potent antitumor activity in vitro and in vivo.The fratricide-resistant FHVH-derived CD5/CD7 bispecific CAR-T cells have potent antitumor activity against T-cell malignancies,and tandem CARs are more effective than dual CAR in preventing tumor escape in heterogeneous leukemic cells.The meaningful clinical efficacy and safety of tandem CD5/CD7 CAR-T cells deserve to be explored urgently. | Zhenyu Dai Wei Mu Ya Zhao Jiali Cheng Haolong Lin Kedong Ouyang Xiangyin Jia Jianwei Liu Qiaoe Wei Meng Wang Chaohong Liu Taochao Tan Jianfeng Zhou | 2022 | Signal Transduction and Targeted Therapy2022，7，4： | 3 |
| 6 | Effects of design parameters on rooftop photovoltaic economics in the urban environment:A case study in Melbourne,Australia显示文摘Many researchers found high potential of adopting building photovoltaic(PV)systems in urban areas,especially on building rooftop,to improve the sustainability of urban environment.However,the optimal energy output performance and economic benefit of the PV system are affected by the usable roof area,PV array layout,and shading effect considering high city density.This study aims to understand the effects of these design parameters in the urban environment of rooftop PV's economic performance.This study carries out a case study in the urban area of Melbourne with 90 PV designs under three shading conditions to generate 270 scenarios.Through a lifecycle cost-benefit analysis,including net present value(NPV),NPV per kW,internal return rate(IRR),and payback year,the results can help in developing a comprehensive understanding of the economic performance of rooftop PV designs that cover most of the urban areas of Melbourne.The optimal PV design scenarios for the urban environment are identified,thereby providing investors and industry professionals with useful information on value-for-money PV design.Meanwhile,the maximum shading loss that makes the PV systems financially unfeasible is investigated,and design scenarios with greatest ability to sustain the shading effect are identified.This research can also support the policy makers'decision on the development and deployment of the roof PV systems in urban planning. | Hongying ZHAO Chaohong YANG W.M·Pabasara U.WIJERATNE Chengyang LIU Xiaolong XUE Nishara ABDEEN | 2019 | Frontiers of Engineering Management2019，6，3： | 2 |
| 7 | Trace Amounts of Triple-Functional Additives Enable Reversible Aqueous Zinc-Ion Batteries from a Comprehensive Perspective显示文摘Although their cost-effectiveness and intrinsic safety,aqueous zinc-ion batteries suffer from notorious side reactions including hydrogen evolution reaction,Zn corrosion and passivation,and Zn dendrite formation on the anode.Despite numerous strategies to alleviate these side reactions have been demonstrated,they can only provide limited performance improvement from a single aspect.Herein,a triple-functional additive with trace amounts,ammonium hydroxide,was demonstrated to comprehensively protect zinc anodes.The results show that the shift of electrolyte pH from 4.1 to 5.2 lowers the HER potential and encourages the in situ formation of a uniform ZHS-based solid electrolyte interphase on Zn anodes.Moreover,cationic NH^(4+)can preferentially adsorb on the Zn anode surface to shield the“tip effect”and homogenize the electric field.Benefitting from this comprehensive protection,dendrite-free Zn deposition and highly reversible Zn plating/stripping behaviors were realized.Besides,improved electrochemical performances can also be achieved in Zn//MnO_(2)full cells by taking the advantages of this triple-functional additive.This work provides a new strategy for stabilizing Zn anodes from a comprehensive perspective. | Ruwei Chen Wei Zhang Quanbo Huang Chaohong Guan Wei Zong Yuhang Dai Zijuan Du Zhenyu Zhang Jianwei Li Fei Guo Xuan Gao Haobo Dong Jiexin Zhu Xiaohui Wang Guanjie He | 2023 | Nano-Micro Letters2023，15，6： | 2 |
| 8 | Foil-like receptor agonists induce apoptosis in mouse 3-cell lymphoma cells by altering NF-κB activation显示文摘 | Nandini Arunkumar Chaohong Liu Haiying Hang Wenxia Song | 2013 | Cellular & Molecular Immunology2013，10，4： | 2 |
| 9 | Study of caffeine binding to human serum albumin using optical spectroscopic methods显示文摘The binding of caffeine to human serum albumin (HSA) under physiological conditions has been stud-ied by the methods of fluorescence,UV-vis absorbance and circular dichroism (CD) spectroscopy. The mechanism of quenching of HSA fluorescence by caffeine was shown to involve a dynamic quenching procedure. The number of binding sites n and apparent binding constant Kb were measured by the fluorescence quenching method and the thermodynamic parameters △H,△G,△S were calculated. The results indicate that the binding is mainly enthalpy-driven,with van der Waals interactions and hydrogen bonding playing major roles in the reaction. The distance r between donor (HSA) and acceptor (caffeine) was obtained according to the Frster theory of non-radiative energy transfer. Synchronous fluorescence,CD and three-dimensional fluorescence spectroscopy showed that the microenvironment and conformation of HSA were altered during the reaction. | WU Qiong LI ChaoHong HU YanJun LIU Yi | 2009 | Science China Chemistry2009，52，12： | 2 |
| 10 | VqMYB154 promotes polygene expression and enhances resistance to pathogens in Chinese wild grapevine显示文摘Resveratrol plays a crucial phytoalexin role in the grapevine and is beneficial to human health.However,the molecular mechanism of resveratrol accumulation in the enhancement of disease resistance is unclear.Here,we report that the transcription factor VqMYB154 from Vitis quinquangularis accession Danfeng-2 is strongly expressed under artificial inoculation with Uncinula necator and regulates resveratrol accumulation.Unlike its homolog,VqMYB154 has a pathogen-induced promoter and responds to stimulation by U.necator,Pseudomonas syringae,and other treatments.Yeast one-hybrid and GUS activity assays confirmed that VqMYB154 can activate the stilbene synthase genes VqSTS9,VqSTS32,and VqSTS42 by directly binding to their promoters.Overexpression of VqMYB154 in grape leaves resulted in activation of the stilbene pathway,upregulation of STS genes,and accumulation of stilbenoids.In addition,heterologous overexpression of VqMYB154 in Arabidopsis activated resistance-related genes and resulted in greater programmed cell death and accumulation of reactive oxygen species,which led to resistance against P.syringae.These results suggest that the transcription factor VqMYB154 from V.quinquangularis accession Danfeng-2 participates in the regulatory mechanism that improves the biosynthesis and accumulation of stilbenes and enhances resistance to disease in grapevine. | Changyue Jiang Dan Wang Jie Zhang Yan Xu Chaohong Zhang Jianxia Zhang Xiping Wang Yuejin Wang | 2021 | Horticulture Research2021，8，1： | 2 |
| 11 | α 1 -Adrenergic receptors mediate combined signals initiated by mechanical stretch stress and norepinephrine leading to accelerated mouse vein graft atherosclerosis显示文摘 | Shuying Liu Yuhuang Li Zhengyu Zhang Fukang Xie Qingbo Xu Xi Huang Jintao Huang Chaohong Li | 2013 | Journal of Vascular Surgery2013，，6： | 2 |
| 12 | Conceptual design of pressure relief systems显示文摘 | PAUL W H C YANG Shuanghua HE Chaohong | 2000 | Journal of Loss Prevention in the Process Industries2000，，13： | 1 |
| 13 | Coherent modulations 显示文摘 | Luo Xiaobing Huang Jiahao Lee Chaohong | 2011 | Phy Rew A2011，84，05： | 1 |
| 14 | 显示文摘 | FangHuachan(方华婵) ChenGenghua(陈庚华) ChaoHong(巢宏)eta1 | 2009 | 粉末冶金材料科学与工程2009，14，6： | 1 |
| 15 | Experimental demonstration of nonlinear quantum metrology with optimal quantum state显示文摘Nonlinear quantum metrology may exhibit better precision scalings. For example, the uncertainty of an estimated phase may scale as ??∝1/(N^2) under quadratic phase accumulation, which is 1/N times smaller than the linear counterpart, where N is probe number. Here, we experimentally demonstrate the nonlinear quantum metrology by using a spin-I(I > 1/2) nuclear magnetic resonance(NMR) ensemble that can be mapped into a system of N=2I spin-1/2 particles and the quadratic interaction can be utilized for the quadratic phase accumulation. Our experimental results show that the phase uncertainty can scale as ??∝1/(N^2-1)by optimizing the input states, when N is an odd number. In addition, the interferometric measurement with quadratic interaction provides a new way for estimating the quadrupolar coupling strength in an NMR system. Our system may be further extended to exotic nonlinear quantum metrology with higher order many-body interactions. | Xinfang Nie Jiahao Huang Zhaokai Li Wenqiang Zheng Chaohong Lee Xinhua Peng Jiangfeng Du | 2018 | Science Bulletin2018，63，8： | 1 |
| 16 | Analytic modeling of the P-doped cascaded Raman fiber lasers显示文摘 | Huang Chaohong Cai Zhiping Ye Chenehun | 2006 | Opt Fiber Teehnol2006，13，1： | 1 |
| 17 | 800 mW/1484 nm highly efficient two-cascaded phos- phosilicate Raman fiber laser pumped by Nd : YVO4 solid-state laser 显示文摘 | Luo Zhengqian Huang Chaohong Sun Guoyong | 2006 | Opt Commun2006，265，2： | 1 |
| 18 | Association of Myeloid-derived Suppressor Cells and Efficacy of Cytokine-induced Killer Cell Immunotherapy in Metastatic Renal Cell Carcinoma Patients显示文摘 | Zibing Wang Yong Zhang Yuqing Liu Li Wang Lingdi Zhao Tiejun Yang Chaohong He Yongping Song Quanli Gao | 2014 | Journal of Immunotherapy2014，，： | 1 |
| 19 | A highly active Au/Al2O3 catalyst for cyclohexane oxidation using molecular oxygen显示文摘 | Xu Lixin He Chaohong Zhu Mingqiao | 2007 | Catal Lett2007，114，34： | 1 |
| 20 | Preparation, Structure and Performances of Cross-Linked Regenerated Cellulose Fibers显示文摘Cross-linked regenerated cellulose fibers(CRCFs) were prepared by wet spinning firstly and then treated by high temperature curing. Cellulose dissolved in ionic liquid together with wrinkle proofing agent and cross-linking agent was employed as spinning solution. The properties and structure of CRCFs were investigated. Fourier transform infrared(FT-IR) spectroscopy and X-ray diffraction(XRD) analysis show that CRCFs were prepared successfully and the crystal form of the fibers remained the same before and after cross-linking. The results indicate that CRCFs prepared in this study possess more excellent wrinkle recovery ability and wash durability than those treated by finishing process. | LIU Jie WANG Huaifang ZHANG Lin SUI Shuying ZHANG Rui DONG Chaohong LIU Yun ZHU Ping | 2019 | Wuhan University Journal of Natural Sciences2019，24，1： | 1 |
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