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| 1 | Effect of Chaihushugan San on expression of the Raf/mitogen-activated protein kinase/extracellular signal-regulated kinase pathway in the hippocampi of perimenopausal rats induced by immobilization stress显示文摘OBJECTIVE: We wished to study the impact of Chaihushugan San(CSS) on the behavior of perimenopausal rats with liver-Qi stagnation(LQS) and to investigate the effect of CSS on signal transduction of the Raf/mitogen-activated protein kinase(MEK)/extracellular signal-regulated kinase(ERK) cascade in the hippocampi of rats induced by immobilization.METHODS: Twenty 52-week-old female rats were divided into two groups by the random number table method: model control group(MCG) and CSS group(CSSG), with 10 rats in each group.Ten-week-old female rats were used as the normal control group(NCG). CSS effects were assessed using rats exposed to immobilization stress by measuring body weight and sucrose consumption, serum hormone levels, and observing performance in the open field test(OFT). Molecular mechanisms were examined by measuring the effect of CSS on expression of Raf1, MEK1/2 and ERK1/2 m RNA in hippocampi using quantitative real-time polymerase chain reaction and by measuring levels of these proteins and related phospho-proteins using Western blotting.RESULTS: Perimenopausal rats with LQS had decreased locomotor activity; reduced sucrose consumption; and increased serum levels of corticotropin releasing hormone(CRH) and corticosterone(CORT). Activation of hippocampal Raf/MEK/ERK cascade was suppressed significantly in the MCG,and activation was increased after 21 days of CSS treatment.CONCLUSION: CSS has significant effects upon relief of the symptoms of LQS in immobilization-induced rats. The mechanism underlying this action might(at least in part) be mediated by reversal of disruption of the Raf/MEK/ERK pathway. | Li Shengqiang Liang Wenna Li Yachan Chen Yunlong Chen Shujiao Li Candong | 2015 | Journal of Traditional Chinese Medicine2015，35，4： | 3 |
| 2 | Novel Donor-Acceptor Copolymers Based on Dithienosilole and Ketone Modified Thieno[3,4-b]thiophene for Photovoltaic Application显示文摘二新奇施主领受人( D-A )共聚物包含 dithienosilole ( DTS )施主单位和酉同类修改了 thieno [ 3,4-b ] thiophene ( TT )领受人单位,也就是 poly {4,4二度( 2-ethylhexyl ) dithieno [ 3,2-b:2,3-d ]silole-5,5-diyl-alt-1-( thieno [ 3,4-b ] thiophen-2-yl )-2-ethylhexan-1-one}( PDTSTT )并且 poly {4,4二度( 2-ethylhexyl ) dithieno [ 3,2-b:2,3-d ]silole-5,5-diyl-alt-1-(4,6二度( 4-ethylhexylthien-2-yl ) thieno [ 3,4-b ] thiophen-2-yl )-2-ethylhexan-1-one}( PDTSDTTT ),在聚合物太阳能电池为申请被综合( PS 聚合物 PDTSTT 和 PDTSDTTT 分别地有 1.54 和 2.02 eV 的电气化学的 bandgaps,和 5.47 和 5.37 eV 的低人精力层次。分子的几何学模拟结果证明与 PDTSTT 相比,在 PDTSDTTT 的 thiophene 桥牌的插入能很好减轻在 TT 和 DTS 单位之间的位的阻碍者,作为由在 DTS 和 DTTT 单位之间的减少的二面的角度证实了。在 AM 1.5G 的照明下面, 100 mW/cm2, PSC 基于 PDTSDTTT/PC61BM (1:1, w:w ) 证明 1.0% 的力量变换效率,它是显著地基于 PDTSTT/PC61BM 与设备比较改善了(1:2, w:w ) 在一样的试验性的条件下面。这是因为提高的 planarity 和在 PDTSDTTT 的主要的链的增加的有效变化形式为费用交通支持更有利的形态学,尽管 PDTSTT 比 PDTSDTTT 拥有更宽广的吸收乐队。 | Lie Chen Shujiao Cai Xianbo Wang Yiwang Chen | 2013 | Chinese Journal of Chemistry2013，31，11： | 1 |
| 3 | Chaetarthria chenjuni Jia & Yang, sp. nov.(Coleoptera: Hydrophilidae), a new species from China and additional faunistic records显示文摘A new species of Chaetarthria Stephens,1835,is described from China,namely Chaetarthria chenjuni Jia&Yang,sp.nov.from Hainan,Guangdong and Guangxi Provinces,China.It is unique in the C.indica group by having the distinct punctures,as strong as those of puncture series,on the elytra.The broad median lobe of aedeagus has a round apex,which can be used to separate it easily from other known species occurring in the Oriental Region. | Fenglong Jia Zhenming Yang Lu Jiang Kai Chen Shujiao Jiang | 2020 | Zoological Systematics2020，45，2： | 0 |
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