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| 1 | TGFβ inhibition enhances the generation of hematopoietic progenitors from human ES cell-derived hemogenic endothelial cells using a stepwise strategy显示文摘 | Chengyan Wang Xuming Tang Xiaomeng Sun Zhenchuan Miao Yaxin Lv Yanlei Yang Huidan Zhang Pengbo Zhang Yang Liu LiyingDu Yang Gao Ming Yin Mingxiao Ding Hongkui Deng | 2012 | Cell Research2012，22，1： | 17 |
| 2 | On the Response of the Global Subduction Rate to Global Warming in Coupled Climate Models显示文摘The response of the global subduction rate to global warming was assessed based on a set of Intergovernmental Panel on Climate Change(IPCC) Fourth Assessment Report(AR4) models. It was found that the subduction rate of the global ocean could be significantly reduced under a warming climate, as compared to a simulation of the present-day climate. The reduction in the subduction volume was quantitatively estimated at about 40 Sv and was found to be primarily induced by the decreasing of the lateral induction term due to a shallower winter mixed layer depth. The shrinking of the winter mixed layer would result from intensified stratification caused by increased heat input into the ocean under a warming climate. A reduction in subduction associated with the vertical pumping term was estimated at about 5 Sv. Further, in the Southern Ocean, a significant reduction in subduction was estimated at around 24 Sv, indicating a substantial contribution to the weakening of global subduction. | LIU Chengyan WANG Zhaomin | 2014 | Advances in Atmospheric Sciences2014，31，1： | 6 |
| 3 | On the Response of Subduction in the South Pacific to an Intensification of Westerlies and Heat Flux in an Eddy Permitting Ocean Model显示文摘Based on an eddy permitting ocean general circulation model, the response of water masses to two distinct climate scenarios in the South Pacific is assessed in this paper. Under annually repeating atmospheric forcing that is characterized by different westerlies and associated heat flux, the response of Subantarctic Mode Water(SAMW) and Antarctic Intermediate Water(AAIW) is quantitatively estimated. Both SAMW and AAIW are found to be warmer, saltier and denser under intensified westerlies and increased heat loss. The increase in the subduction volume of SAMW and AAIW is about 19.8 Sv(1 Sv =10~6m^3s^(-1)). The lateral induction term plays a dominant role in the changes in the subduction volume due to the deepening of the mixed layer depth(MLD). Furthermore, analysis of the buoyancy budget is used to quantitatively diagnose the reason for the changes in the MLD. The deepening of the MLD is found to be primarily caused by the strengthening of heat loss from the ocean to the atmosphere in the formation region of SAMW and AAIW. | Chengyan LIU Zhaomin WANG Bingrui LI Chen CHENG Ruibin XIA | 2017 | Advances in Atmospheric Sciences2017，34，4： | 5 |
| 4 | On the subtropical Northeast Pacific mixed layer depth and its influence on the subduction显示文摘The present climate simulations of the mixed layer depth(MLD) and the subduction rate in the subtropical Northeast Pacific are investigated based on nine of the CMIP5 models. Compared with the observation data,spatial patterns of the MLD and the subduction rate are well simulated in these models. The spatial pattern of the MLD is nonuniform, with a local maximum MLD(>140 m) region centered at(28°N, 135°W) in late winter. The nonuniform MLD pattern causes a strong MLD front on the south of the MLD maximum region, controls the lateral induction rate pattern, and then decides the nonuniform distribution of the subduction rate. Due to the inter-regional difference of the MLD, we divide this area into two regions. The relatively uniform Ekman pumping has little effect on the nonuniform subduction spatial pattern, though it is nearly equal to the lateral induction in values. In the south region, the northward warm Ekman advection(–1.75×10^(–7) K/s) controls the ocean horizontal temperature advection(–0.85×10^(–7) K/s), and prevents the deepening of the MLD. In the ensemble mean, the contribution of the ocean advection to the MLD is about –29.0 m/month, offsetting the sea surface net heat flux contribution(33.9 m/month). While in the north region, the southward cold advection deepens the MLD(21.4 m/month) as similar as the heat flux(30.4 m/month). In conclusion, the nonuniform MLD pattern is dominated by the nonuniform ocean horizontal temperature advection. This new finding indicates that the upper ocean current play an important role in the variability of the winter MLD and the subduction rate. | XIA Ruibin LIU Chengyan CHENG Chen | 2018 | Acta Oceanologica Sinica2018，37，3： | 4 |
| 5 | Optimal yield-related attributes of irrigated rice for high yield potential based on path analysis and stability analysis显示文摘Improvement of yield in rice(Oryza sativa L.) is vital for ensuring food security in China. Both rice breeders and growers need an improved understanding of the relationship between yield and yield-related traits. New indica cultivars(53 in 2007 and 48 in 2008) were grown in Taoyuan,Yunnan province, to identify important components contributing to yield. Additionally, two standard indica rice cultivars with similar yield potentials, II You 107(a large-panicle type) and Xieyou 107(a heavy-panicle type), were planted in Taoyuan, Yunnan province and Nanjing,Jiangsu province, from 2006 to 2008 to evaluate the stability of yield and yield-related attributes.Growth duration(GD), leaf area index(LAI), panicles per m2(PN), and spikelets per m2(SM) were significantly and positively correlated with grain yield(GY) over all years. Sequential path analysis identified PN and panicle weight(PW) as important first-order traits that influenced grain yield. All direct effects were significant, as indicated by bootstrap analysis. Yield potential varied greatly across locations but not across years. Plant height(PH), days from heading to maturity(HM), and grain weight(GW) were stable traits that showed little variation across sites or years, whereas GD(mainly the pre-heading period, PHP) and PN varied significantly across locations. To achieve a yield of 15 t ha-1, a cultivar should have a PH of 110–125 cm, a long GD with HM of approximately 40 days, a PN of 300–400 m-2, and a GW of 29–31 mg. | Ganghua Li Jun Zhang Congdang Yang Yunpan Song Chengyan Zheng Shaohua Wang Zhenghui Liu Yanfeng Ding | 2014 | The Crop Journal2014，2，4： | 4 |
| 6 | Guards at the gate: physiological and pathological roles of tissue-resident innate lymphoid cells in the lung显示文摘 | Hang Cheng Chengyan Jin Jing Wu Shan Zhu Yong-Jun Liu Jingtao Chen | 2017 | Protein & Cell2017，8，12： | 3 |
| 7 | Efficient recovery of valuable metals from waste printed circuit boards by microwave pyrolysis显示文摘The recycling of waste printed circuit board(WPCBs) is of great significance for saving resources and protecting the environment. In this study, the WPCBs were pyrolyzed by microwave and the contained valuable metals Cu, Sn and Pb were recovered from the pyrolyzed WPCBs. The effect of pyrolysis temperature and time on the recovery efficiency of valuable metals was investigated. Additionally, the characterization for morphology and surface elemental distribution of pyrolysis residues was carried out to investigate the pyrolysis mechanism. The plastic fiber boards turned into black carbides, and they can be easily separated from the metals by manual. The results indicate that 91.2%, 96.1% and 94.4% of Cu, Sn and Pb can be recovered after microwave pyrolysis at 700 °C for 60 minutes. After pyrolysis, about 79.8%(mass)solid products, 11.9%(mass) oil and 8.3%(mass) gas were produced. These gas and oil can be used as fuel and raw materials of organic chemicals, respectively. This process provides an efficient and energy-saving technology for recovering valuable metals from WPCBs. | Yubo Liu Jialiang Zhang Xu Yang Wenguang Yang Yongqiang Chen Chengyan Wang | 2021 | Chinese Journal of Chemical Engineering2021，34，12： | 2 |
| 8 | Evaluation of Arctic Sea Ice Drift and its Relationship with Near-surface Wind and Ocean Current in Nine CMIP6 Models from China显示文摘The simulated Arctic sea ice drift and its relationship with the near-surface wind and surface ocean current during 1979-2014 in nine models from China that participated in the sixth phase of the Coupled Model Intercomparison Project(CMIP6)are examined by comparison with observational and reanalysis datasets.Most of the models reasonably represent the Beaufort Gyre(BG)and Transpolar Drift Stream(TDS)in the spatial patterns of their long-term mean sea ice drift,while the detailed location,extent,and strength of the BG and TDS vary among the models.About two-thirds of the models agree with the observation/reanalysis in the sense that the sea ice drift pattern is consistent with the near-surface wind pattern.About the same proportion of models shows that the sea ice drift pattern is consistent with the surface ocean current pattern.In the observation/reanalysis,however,the sea ice drift pattern does not match well with the surface ocean current pattern.All nine models missed the observational widespread sea ice drift speed acceleration across the Arctic.For the Arctic basin-wide spatial average,five of the nine models overestimate the Arctic long-term(1979-2014)mean sea ice drift speed in all months.Only FGOALS-g3 captures a significant sea ice drift speed increase from 1979 to 2014 both in spring and autumn.The increases are weaker than those in the observation.This evaluation helps assess the performance of the Arctic sea ice drift simulations in these CMIP6 models from China. | Xiaoyong YU Chengyan LIU Xiaocun WANG Jian CAO Jihai DONG Yu LIU | 2022 | Advances in Atmospheric Sciences2022，39，6： | 2 |
| 9 | Multifunctional Fibroblasts Enhanced via Thermal and Freeze-Drying Post-treatments of Aligned Electrospun Nanofiber Membranes显示文摘Parallel fibrous scaffolds play a critical role in controlling the morphology of cells to be more natural and biologically inspired.Among popular tissue engineering materials,poly(2-hydroxyethyl methacrylate)(pHEMA)has been widely investigated in conventional forms due to its biocompatibility,low toxicity,and hydrophilicity.However,the swelling of pHEMA in water remains a major concern.To address this issue,randomly oriented and aligned as-spun pHEMA nanofibrous scaffolds were first fabricated at speeds of 300 and 2000 rpm in this study,which were then post-treated using either a thermal or a freeze-drying method.In cell assays,human dermal fibroblasts(HDFs)adhered to the freeze-drying treated substrates at a significantly faster rate,whereas they had a higher cell growth rate on thermally-treated substrates.Results indicated that the structural properties of pHEMA nanofibrous scaffolds and subsequent cellular behaviors were largely dependent on post-treatment methods.Moreover,this study suggests that aligned pHEMA nanofibrous substrates tended to induce regular fibroblast orientation and unidirectionally oriented actin cytoskeletons over random pHEMA nanofibrous substrates.Such information has predictive power and provides insights into promising post-treatment methods for improving the properties of aligned pHEMA scaffolds for numerous tissue engineering applications. | Ya Li Qian Shen Jing Shen Xinbo Ding Tao Liu Jihuan He Chengyan Zhu Ding Zhao Jiadeng Zhu | 2021 | Advanced Fiber Materials2021，3，1： | 2 |
| 10 | On the determination and simulation of seawater freezing point temperature under high pressure显示文摘At present,it is believed that the freezing point temperature of seawater is a function of salinity and pressure,and the freezing point is a key parameter in a coupled air-sea-ice system.Generally,empirical formulas or methods are used to calculate the freezing point of seawater.Especially in high-pressure situations,e.g.,under a thick ice sheet or ice shelf,the pressure term must be taken into account in the determination of seawater freezing point temperature.This study summarized various methods that have been used to calculate seawater freezing point with high pressure.The methods that were employed in two ocean-ice models were also assessed.We identified the disadvantages of these methods used in these two models and addressed the corresponding uncertainties of the freezing point temperature formulas.This study provides useful information on the calculation of the freezing point temperature in numerical modeling and indicates a need to investigate the sensitivity of numerical simulations to the uncertainties in the freezing point temperature in future. | YAN Liangjun WANG Zhaomin LIU Chengyan WU Yang | 2019 | Advances in Polar Science2019，30，4： | 2 |
| 11 | Impacts of High-Frequency Atmospheric Forcing on Southern OceanCirculation and Antarctic Sea Ice显示文摘The relative contributions of atmospheric fluctuations on 6 h?2 d,2?8 d,and 8 d?1 month time scales to the changes in the air?sea fluxes,the SO circulation,and Antarctic sea ice are investigated.It was found that the imposed forcing variability on the three time scales creates a significant increase in wind power input,and hence an increase of about 50%,97%,and 5%of eddy kinetic energy relative to the simulation driven by monthly forcing,respectively.Also,SO circulation and the strength of the upper cell of meridional overturning circulation become strengthened.These results indicate more dominant effects of atmospheric variability on the 2?8 d time scale on the SO circulation.Meanwhile,the 6 h?2 d(2?8 d)atmospheric variability causes an increase in the total sea-ice extent,area,and volume,by about 33%,30%,and 19%(17%,20%,and 25%),respectively,relative to those in the experiment forced by monthly atmospheric variables.Such significant sea-ice increases are caused by a cooler ocean surface and stronger sea-ice transports owing to the enhanced heat losses and air-ice stresses induced by the atmospheric variability at 6 h?2 d and 2?8 d,while the effects of the variability at 8 d?1 month are rather weak.The influences of atmospheric variability found here mainly result from wind fluctuations.Our findings in this study indicate the importance of properly resolving high-frequency atmospheric variability in modeling studies. | Yang WU Zhaomin WANG Chengyan LIU and Xia LIN | 2020 | Advances in Atmospheric Sciences2020，37，5： | 1 |
| 12 | Bisphenol A induces oxidative stress-associated DNA damage in INS-1 cells显示文摘 | Fei Xin Liping Jiang Xiaofang Liu Chengyan Geng Wenbin Wang Laifu Zhong Guang Yang Min Chen | 2014 | Mutation Research - Genetic Toxicology and Environmental Mutagenesis2014，，： | 1 |
| 13 | 99mTc-labeled RGD-BBN peptide for small-animal SPECT/CT of lung carcinoma显示文摘 | Liu Zhaofei Huang Jinming Dong Chengyan | 2012 | Molecular Pharma- ceutics2012，9，5： | 1 |
| 14 | Thermoelectric enhancement of p-type Si_(80)Ge_(20) alloy via co-compositing of dual oxides:Respective regulation for power factor and thermal conductivity byβ-Ga_(2)O_(3) and SiO_(2) aerogel powders显示文摘Si-based thermoelectric(TE)materials are exhibiting remarkable perspectives in self-energized applications with their special advantages.However,the relatively high total thermal conductivity(κ)prevents their TE enhancement.Here,a strategy of co-compositing dual oxides was implemented for enhancing the TE properties of p-type Si_(80)Ge_(20) bulks.Composited Ga2O_(3) was demonstrated to enhance the power factor(PF)due to the crystallization-induced effect of produced Ga by decomposition on SiGe matrix.Associating with compositing SiO_(2) aerogel(a-SiO_(2))powder,not only introduced the fine amorphous inclusions and decreased the grain size of host matrix,but also various nano morphologies were formed,i.e.,nano inclusions,precipitations,twin boundaries(TBs),and faults.Combining with the eutectic Ge,hierarchical scattering centers impeded the phonon transport comprehensively(decreasing the phonon group velocity(a v)and relaxation time)for reducing the lattice-induced thermal conductivity(lκ).As a result,a minimumκof 2.38 W·m^(−1)·K^(−1) was achieved,which is significantly dropped by 32.6%in contrast with that of the pristine counterpart.Ultimately,a maximal dimensionless figure of merit(ZT)of 0.9 was achieved at 600℃,which is better than those of most corresponding oxide-composited Si-based bulks. | Huajun LAI Ying PENG Mengfei WANG Runze SHI Junliang CHEN Chengyan LIU Yifeng WANG Lei MIAO Haiqiao WEI | 2023 | Journal of Advanced Ceramics2023，12，2： | 1 |
| 15 | An Integration Strategy to Develop Dual-State Luminophores with Tunable Spectra,Large Stokes Shift,and Activatable Fluorescence for High-Contrast Imaging显示文摘Developing dual-state luminophores(DSLs)with strong fluorescence in both the monomer and aggregate states is urgently needed but remains a huge challenge because most current luminophores are either aggregation-induced emission or aggregation-caused quenching molecules.Moreover,limited by the structural conservation of the few existing DSLs,there are not enough response sites that can be used to customize various activatable fluorescent probes for specific molecular imaging.Herein,we engineered a general integration strategy for the fabrication of such DSLs with excellent photophysical properties.The DSLs,with their tunable spectra,a large Stokes shift(>170 nm),and achievable near-infrared(NIR)emission,show great potential for high-contrast imaging.Importantly,DSLs can be used as a universal platform for probe customization due to their activatable fluorescence through protection-deprotection of the phenolic hydroxyl group.Based on this,an NIR fluorescent probe DSL-Gal was developed for sensing of β-galactosidase in solutions,senescent cells,and liver metastases with high contrast,further confirming the superiority and universal feasibility of DSLs in probe design.The integration strategy may provide a novel approach for the generation of other DSLs and have great potential applications in bioimaging. | Yongchao Liu Lili Teng Chengyan Xu Tian-Bing Ren Shuai Xu Xiaofeng Lou Lin Yuan Xiao-Bing Zhang | 2022 | CCS Chemistry2022，4，6： | 1 |
| 16 | Beneficial effects of neomangiferin on high fat diet-induced nonalcoholic fatty liver disease in rats显示文摘 | Chengyan Zhou Jingjing Zhou Na Han Zhihui Liu Bin Xiao Jun Yin | 2015 | International Immunopharmacology2015，，1： | 1 |
| 17 | Understanding the geometric and electronic factors of PtNi bimetallic surfaces for efficient and selective catalytic hydrogenation of biomass-derived oxygenates显示文摘Ni-base catalysts are promising candidate for the hydrogenation of furfural(FAL) to high-value chemicals.However,slow intermediate desorption and low selectivity limit its implementation.Identifying the catalytic performance of each active sites is vital to design hydrogenation catalyst,and tuning the geometrical sites at molecule level in PtNi could lead to the modification of electronic structure,and thus the selectity for the hydrogenation of FAL was modulated.Herein,PtNi hollow nanoframes(PtNi HNFs) with three dimensional(3 D) molecular accessibility were synthesized,EDX results suggested that Ni was evenly distributed inside of the hollow nanoframes,whereas Pt was relatively concentrated at the edges.DFT calculation demonstrated that PtNi significant decrease the desorption energy of the intermediates.This strategy could not only enhance the desorption of intermediates to improve the catalytic performance,but also transfer the adsorption mode of FAL on catalyst surface to selective hydrogenation of FAL to FOL or THFA.The PtNi HNFs catalyst afforded excellent catalytic performance for selective hydrogenation of a broad range of biomass-derived platform chemicals under mild conditions,especially of FAL to furfuryl alcohol(FOL),in quantitative FOL yields(99%) with a high TOF of 2.56 h^(-1).It is found that the superior performance of PtNi HNFs is attributed to its 3 D hierarchical structure and synergistic electronic effects between Pt and Ni.Besides,the kinetic study demonstrated that the activation energy for hydrogenation of FAL was as low as 54.95 kJ mol^(-1). | Jingcheng Wu Chuangwei Liu Yuting Zhu Xiangbo Song Chengyan Wen Xinghua Zhang Chenguang Wang Longlong Ma | 2021 | Journal of Energy Chemistry2021，30，9： | 1 |
| 18 | Realizing high thermoelectric performance for p-type SiGe in medium temperature region via TaC compositing显示文摘SiGe is recognised as an excellent thermoelectric material with superior mechanical properties and thermal stability in regions with high temperatures.This study explores a novel strategy for coregulating thermoelectric transport parameters to achieve high thermoelectric properties of p-type SiGe in the mid-temperature region by incorporating nano-TaC into SiGe combined ball milling with spark plasma sintering.By optimizing the amount of TaC in the SiGe matrix,the power factors were significantly increased due to the modulation doping effect based on the work function matching of SiGe with TaC.Simultaneously,the ensemble effect of the nanostructure leads to a significant decrease in thermal conductivity.Thus,a high ZT of 1.06 was accomplished at 873 K,which is 64%higher than that of typical radioisotope thermoelectric generator.Our research offers a novel strategy for expanding and enhancing the thermoelectric properties of SiGe materials in the medium temperature range. | Zheng Fan JiSheng Liang Jun-Liang Chen Ying Peng Huajun Lai Jian Nong Chengyan Liu Wangyang Ding Lei Miao | 2023 | Journal of Materiomics2023，9，5： | 1 |
| 19 | Carrier and microstructure tuning for improving the thermoelectric properties of Ag_(8)SnSe_(6)via introducing SnBr_(2)显示文摘The argyrodite compounds(2 A(12)/B X6 m n n^(m+)+--(Am+=Li^(+),Cu^(+),and Ag^(+);Bn^(+)=Ga^(3+),Si^(4+),Ge^(4+),Sn^(4+),P^(5+),and As^(5+);and X^(2−)=S^(2−),Se^(2−),or Te^(2−)))have attracted great attention as excellent thermoelectric(TE)materials due to their extremely low lattice thermal conductivity(κl).Among them,Ag_(8)SnSe_(6)-based TE materials have high potential for TE applications.However,the pristine Ag_(8)SnSe_(6)materials have low carrier concentration(<1017 cm^(−3)),resulting in low power factors.In this study,a hydrothermal method was used to synthesize Ag_(8)SnSe_(6)with high purity,and the introduction of SnBr_(2)into the pristine Ag_(8)SnSe_(6)powders has been used to simultaneously increase the power factor and decrease the thermal conductivity(κ).On the one hand,a portion of the Br−ions acted as electrons to increase the carrier concentration,increasing the power factor to a value of~698 mW·m^(−1)·K^(−2)at 736 K.On the other hand,some of the dislocations and nanoprecipitates(SnBr_(2))were generated,resulting in a decrease ofκl(~0.13 W·m^(−1)·K^(−1))at 578 K.As a result,the zT value reaches~1.42 at 735 K for the sample Ag8Sn1.03Se5.94Br0.06,nearly 30%enhancement in contrast with that of the pristine sample(~1.09).The strategy of synergistic manipulation of carrier concentration and microstructure by introducing halogen compounds could be applied to the argyrodite compounds to improve the TE properties. | Zhonghai YU Xiuxia WANG Chengyan LIU Yiran CHENG Zhongwei ZHANG Ruifan SI Xiaobo BAI Xiaokai HU Jie GAO Ying PENG Lei MIAO | 2022 | Journal of Advanced Ceramics2022，11，7： | 1 |
| 20 | Administration of Yeast Glucan on Immunity of Offspring in Turbot Scophthalmus maximus: A Trans-Generational Immune-Enhancing Effect显示文摘β-glucan has been shown to increase immunity and survival in various juvenile and adult fish both in freshwater and marine aquaculture species as well as in marine fish larvae. However, information about the trans-generational immune-enhancing effects of β-glucan remains rather limited. Here we clearly show that dietary intake of β-glucan enhanced the levels of C3, Bf and lysozyme in the serum of turbot as well as in their eggs released. We also show that yeast glucan induced a significant increase in lysozyme activity in both the serum and eggs. Moreover, the embryos derived from yeast glucan-treated turbot were more resistant to bacterial challenge than control embryos. By contrast, the administration of yeast glucan on female turbots had little influence on the egg development and embryonic development. Collectively, these data indicate that yeast glucan can be safely used to promote the non-specific trans-generational immunity in offspring of turbot. | JIANG Chengyan WANG Peng LIU Shousheng WANG Yanfeng LI Jun JI Guangdong | 2019 | Journal of Ocean University of China2019，18，4： | 1 |
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